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Select item 96543921.

Upregulation of Na_v1.6 Mediated by the p38 MAPK Pathway in the Dorsal Root Ganglia Contributes to Cancer-Induced Bone Pain in Rats

Mingxue Lin, Xiaohui Chen, Shuyan Wu, Pinzhong Chen, Haiyang Wan, Simeng Ma, Na Lin, Yanling Liao, Ting Zheng, Jundan Jiang, Xiaochun Zheng

Cells. 2022 Nov; 11(21): 3375. Published online 2022 Oct 26. doi: 10.3390/cells11213375

PMCID:: PMC9654392

Abstract Article PDF–3.8M

Select item 67297062.

Fibroblast Growth Factor Homologous Factor 2B: Association with Na_v1.6 and Selective Colocalization at Nodes of Ranvier of Dorsal Root Axons

Ellen K. Wittmack, Anthony M. Rush, Matthew J. Craner, Mitchell Goldfarb, Stephen G. Waxman, Sulayman D. Dib-Hajj

J Neurosci. 2004 Jul 28; 24(30): 6765–6775. doi: 10.1523/JNEUROSCI.1628-04.2004

PMCID:: PMC6729706

Abstract Article PDF–607K

Select item 67254173.

Voltage-Gated Sodium Channel Na_v1.6 Is Modulated by p38 Mitogen-Activated Protein Kinase

Ellen K. Wittmack, Anthony M. Rush, Andy Hudmon, Stephen G. Waxman, Sulayman D. Dib-Hajj

J Neurosci. 2005 Jul 13; 25(28): 6621–6630. doi: 10.1523/JNEUROSCI.0541-05.2005

PMCID:: PMC6725417

Abstract Article PDF–475K

Select item 67248244.

Sodium Currents in Medullary Neurons Isolated from the Pre-Bötzinger Complex Region

Krzysztof Ptak, Greer G. Zummo, George F. Alheid, Tatiana Tkatch, D. James Surmeier, Donald R. McCrimmon

J Neurosci. 2005 May 25; 25(21): 5159–5170. doi: 10.1523/JNEUROSCI.4238-04.2005

PMCID:: PMC6724824

Abstract Article PDF–496K

Select item 66728495.

Reduced Sodium Current in Purkinje Neurons from Na_V1.1 Mutant Mice: Implications for Ataxia in Severe Myoclonic Epilepsy in Infancy

Franck Kalume, Frank H. Yu, Ruth E. Westenbroek, Todd Scheuer, William A. Catterall

J Neurosci. 2007 Oct 10; 27(41): 11065–11074. doi: 10.1523/JNEUROSCI.2162-07.2007

PMCID:: PMC6672849

Abstract Article PDF–941K

Select item 66722416.

Na_v1.1 Localizes to Axons of Parvalbumin-Positive Inhibitory Interneurons: A Circuit Basis for Epileptic Seizures in Mice Carrying an Scn1a Gene Mutation

Ikuo Ogiwara, Hiroyuki Miyamoto, Noriyuki Morita, Nafiseh Atapour, Emi Mazaki, Ikuyo Inoue, Tamaki Takeuchi, Shigeyoshi Itohara, Yuchio Yanagawa, Kunihiko Obata, Teiichi Furuichi, Takao K. Hensch, Kazuhiro Yamakawa

J Neurosci. 2007 May 30; 27(22): 5903–5914. doi: 10.1523/JNEUROSCI.5270-06.2007

PMCID:: PMC6672241

Abstract Article PDF–1.0M

Select item 65782327.

A novel, abundant sodium channel expressed in neurons and glia

KL Schaller, DM Krzemien, PJ Yarowsky, BK Krueger, JH Caldwell

J Neurosci. 1995 May 1; 15(5): 3231–3242. doi: 10.1523/JNEUROSCI.15-05-03231.1995

PMCID:: PMC6578232

Abstract PDF–5.1M

Select item 64418418.

Role of Na_V1.6 and Na_Vβ4 sodium channel subunits in a rat model of low back pain induced by compression of the dorsal root ganglia

Wenrui Xie, Jingdong Zhang, Judith A. Strong, Jun-Ming Zhang

Neuroscience. Author manuscript; available in PMC 2020 Mar 15.

Published in final edited form as: Neuroscience. 2019 Mar 15; 402: 51–65. Published online 2019 Jan 27. doi: 10.1016/j.neuroscience.2019.01.012

PMCID:: PMC6441841

Abstract Article PDF–1.9M

Select item 60524979.

Nonmuscle myosin II isoforms interact with sodium channel alpha subunits

Bhagirathi Dash, Chongyang Han, Stephen G Waxman, Sulayman D Dib-Hajj

Mol Pain. 2018; 14: 1744806918788638. Published online 2018 Jul 18. doi: 10.1177/1744806918788638

PMCID:: PMC6052497

Abstract Article PDF–818K

Select item 513148810.

Remarkable alterations of Nav1.6 in reactive astrogliosis during epileptogenesis

Hongyan Zhu, Yuxiao Zhao, Hao Wu, Nan Jiang, Ziyi Wang, Weide Lin, Jiahui Jin, Yonghua Ji

Sci Rep. 2016; 6: 38108. Published online 2016 Dec 1. doi: 10.1038/srep38108

PMCID:: PMC5131488

Abstract Article PDF–2.3M

Select item 503471711.

Single-Molecule Imaging of Na_v1.6 on the Surface of Hippocampal Neurons Reveals Somatic Nanoclusters

Elizabeth J. Akin, Laura Solé, Ben Johnson, Mohamed el Beheiry, Jean-Baptiste Masson, Diego Krapf, Michael M. Tamkun

Biophys J. 2016 Sep 20; 111(6): 1235–1247. Published online 2016 Sep 20. doi: 10.1016/j.bpj.2016.08.016

PMCID:: PMC5034717

Abstract Article PDF–2.2M

Select item 449018512.

Characterization of a de novo SCN8A mutation in a patient with epileptic encephalopathy

Carolien G.F. de Kovel, Miriam H. Meisler, Eva H. Brilstra, Frederique M.C. van Berkestijn, Ruben van ‘t Slot, Stef van Lieshout, Isaac J Nijman, Janelle E. O'Brien, Michael F. Hammer, Mark Estacion, Stephen G. Waxman, Sulayman D. Dib-Hajj, Bobby P.C. Koeleman

Epilepsy Res. Author manuscript; available in PMC 2015 Jul 3.

Published in final edited form as: Epilepsy Res. 2014 Nov; 108(9): 1511–1518. Published online 2014 Sep 4. doi: 10.1016/j.eplepsyres.2014.08.020

PMCID:: PMC4490185

Abstract Article PDF–1.0M

Select item 441374313.

De novo gain-of-function and loss-of-function mutations of SCN8A in patients with intellectual disabilities and epilepsy

Maxime G Blanchard, Marjolein H Willemsen, Jaclyn B Walker, Sulayman D Dib-Hajj, Stephen G Waxman, Marjolijn CJ Jongmans, Tjitske Kleefstra, Bart P van de Warrenburg, Peter Praamstra, Joost Nicolai, Helger G Yntema, René JM Bindels, Miriam H Meisler, Erik-Jan Kamsteeg

J Med Genet. 2015 May; 52(5): 330–337. Published online 2015 Feb 27. doi: 10.1136/jmedgenet-2014-102813

PMCID:: PMC4413743

Abstract Article PDF–1.3M

Select item 439842314.

Preferential Targeting of Na_v1.6 Voltage-Gated Na⁺ Channels to the Axon Initial Segment during Development

Elizabeth J. Akin, Laura Solé, Sulayman D. Dib-Hajj, Stephen G. Waxman, Michael M. Tamkun

PLoS One. 2015; 10(4): e0124397. Published online 2015 Apr 15. doi: 10.1371/journal.pone.0124397

PMCID:: PMC4398423

Abstract Article PDF–1.4M

Select item 436944715.

Local knockdown of the Na_V1.6 sodium channel reduces pain behaviors, sensory neuron excitability, and sympathetic sprouting in rat models of neuropathic pain

Wenrui Xie, Judith A. Strong, Jun-Ming Zhang

Neuroscience. Author manuscript; available in PMC 2016 Apr 16.

Published in final edited form as: Neuroscience. 2015 Apr 16; 291: 317–330. Published online 2015 Feb 14. doi: 10.1016/j.neuroscience.2015.02.010

PMCID:: PMC4369447

Abstract Article PDF–1.7M

Select item 370764216.

The Fibroblast Growth Factor 14·Voltage-gated Sodium Channel Complex Is a New Target of Glycogen Synthase Kinase 3 (GSK3)

Alexander S. Shavkunov, Norelle C. Wildburger, Miroslav N. Nenov, Thomas F. James, Tetyana P. Buzhdygan, Neli I. Panova-Elektronova, Thomas A. Green, Ronald L. Veselenak, Nigel Bourne, Fernanda Laezza

J Biol Chem. 2013 Jul 5; 288(27): 19370–19385. Published online 2013 May 2. doi: 10.1074/jbc.M112.445924