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Items: 1 to 20 of 32

1.
Lipid-associated macrophages’ promotion of fibrosis resolution during MASH regression requires TREM2
Souradipta Ganguly, Sara Brin Rosenthal, Kei Ishizuka, Ty D. Troutman, Theresa V. Rohm, Naser Khader, German Aleman-Muench, Yasuyo Sano, Sebastiano Archilei, Pejman Soroosh, Jerrold M. Olefsky, Ariel E. Feldstein, Tatiana Kisseleva, Rohit Loomba, Christopher K. Glass, David A. Brenner, Debanjan Dhar
Proc Natl Acad Sci U S A. 2024 Aug 27; 121(35): e2405746121. Published online 2024 Aug 22. doi: 10.1073/pnas.2405746121
PMCID:
PMC11363294
AbstractArticlePDF–2.8M
2.
Female Alms1-deficient mice develop echocardiographic features of adult but not infantile Alström syndrome cardiomyopathy
Eleanor J. McKay, Ineke Luijten, Sophie Broadway-Stringer, Adrian Thomson, Xiong Weng, Katya Gehmlich, Gillian A. Gray, Robert K. Semple
Dis Model Mech. 2024 Jun 1; 17(6): dmm050561. Published online 2024 Jun 28. doi: 10.1242/dmm.050561
PMCID:
PMC11225586
AbstractArticle
3.
Mesenchymal-specific Alms1 knockout in mice recapitulates metabolic features of Alström syndrome
Eleanor J. McKay, Ineke Luijten, Xiong Weng, Pablo B. Martinez de Morentin, Elvira De Frutos González, Zhanguo Gao, Mikhail G. Kolonin, Lora K. Heisler, Robert K. Semple
Mol Metab. 2024 Jun; 84: 101933. Published online 2024 Apr 6. doi: 10.1016/j.molmet.2024.101933
PMCID:
PMC11047791
AbstractArticlePDF–2.2M
4.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
5.
Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models
Yunlu Xue, Xiaomei Sun, Sean K. Wang, Gayle B. Collin, Vladimir J. Kefalov, Constance L. Cepko
Proc Natl Acad Sci U S A. 2023 Jun 6; 120(23): e2217885120. Published online 2023 May 30. doi: 10.1073/pnas.2217885120
PMCID:
PMC10266038
AbstractArticlePDF–5.5M
6.
Nonalcoholic Steatohepatitis and HCC in a Hyperphagic Mouse Accelerated by Western Diet
Souradipta Ganguly, German Aleman Muench, Linshan Shang, Sara Brin Rosenthal, Gibraan Rahman, Ruoyu Wang, Yanhan Wang, Hyeok Choon Kwon, Anthony M. Diomino, Tatiana Kisseleva, Pejman Soorosh, Mojgan Hosseini, Rob Knight, Bernd Schnabl, David A. Brenner, Debanjan Dhar
Cell Mol Gastroenterol Hepatol. 2021; 12(3): 891–920. Published online 2021 May 29. doi: 10.1016/j.jcmgh.2021.05.010
PMCID:
PMC8342972
AbstractArticlePDF–9.5M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
Relative Adipose Tissue Failure in Alström Syndrome Drives Obesity-Induced Insulin Resistance
Tarekegn Geberhiwot, Shanat Baig, Cathy Obringer, Dorothée Girard, Charlotte Dawson, Konstantinos Manolopoulos, Nadia Messaddeq, Pierre Bel Lassen, Karine Clement, Jeremy W. Tomlinson, Richard P. Steeds, Hélène Dollfus, Nikolai Petrovsky, Vincent Marion
Diabetes. 2021 Feb; 70(2): 364–376. Published online 2020 Sep 29. doi: 10.2337/db20-0647
PMCID:
PMC7881858
AbstractArticlePDF–1.8M
9.
Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss
Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs
Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931
PMCID:
PMC7227028
AbstractArticlePDF–5.4M
10.
Bone marrow‐derived macrophage contributes to fibrosing steatohepatitis through activating hepatic stellate cells
Juqiang Han, Xiang Zhang, Jennie K‐C Lau, Kaili Fu, Harry CH Lau, Weiqi Xu, Eagle SH Chu, Huiyao Lan, Jun Yu
J Pathol. 2019 Aug; 248(4): 488–500. Published online 2019 May 7. doi: 10.1002/path.5275
PMCID:
PMC6767065
AbstractArticlePDF–5.7M
11.
CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice
Jin Li, Su-Ping Deng, Gang Wei, Peng Yu
Database (Oxford) 2018; 2018: bay012. Published online 2018 Mar 23. doi: 10.1093/database/bay012
PMCID:
PMC5868181
AbstractArticlePDF–653K
12.
Mouse models of human ocular disease for translational research
Mark P. Krebs, Gayle B. Collin, Wanda L. Hicks, Minzhong Yu, Jeremy R. Charette, Lan Ying Shi, Jieping Wang, Jürgen K. Naggert, Neal S. Peachey, Patsy M. Nishina
PLoS One. 2017; 12(8): e0183837. Published online 2017 Aug 31. doi: 10.1371/journal.pone.0183837
PMCID:
PMC5578669
AbstractArticlePDF–26M
13.
Disruption of SorCS2 reveals differences in the regulation of stereociliary bundle formation between hair cell types in the inner ear
Andrew Forge, Ruth R. Taylor, Sally J. Dawson, Michael Lovett, Daniel J. Jagger
PLoS Genet. 2017 Mar; 13(3): e1006692. Published online 2017 Mar 27. doi: 10.1371/journal.pgen.1006692
PMCID:
PMC5386298
AbstractArticlePDF–6.5M
14.
Animal models of non‐alcoholic fatty liver disease: current perspectives and recent advances
Jennie Ka Ching Lau, Xiang Zhang, Jun Yu
J Pathol. 2017 Jan; 241(1): 36–44. Published online 2016 Nov 22. doi: 10.1002/path.4829
PMCID:
PMC5215469
AbstractArticlePDF–5.8M
15.
The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway
Zakia A. Abdelhamed, Subaashini Natarajan, Gabrielle Wheway, Christopher F. Inglehearn, Carmel Toomes, Colin A. Johnson, Daniel J. Jagger
Dis Model Mech. 2015 Jun 1; 8(6): 527–541. doi: 10.1242/dmm.019083
PMCID:
PMC4457033
AbstractArticle
16.
GLUT4 Defects in Adipose Tissue Are Early Signs of Metabolic Alterations in Alms1GT/GT, a Mouse Model for Obesity and Insulin Resistance
Francesca Favaretto, Gabriella Milan, Gayle B. Collin, Jan D. Marshall, Fabio Stasi, Pietro Maffei, Roberto Vettor, Jürgen K. Naggert
PLoS One. 2014; 9(10): e109540. Published online 2014 Oct 9. doi: 10.1371/journal.pone.0109540
PMCID:
PMC4192353
AbstractArticlePDF–1.1M
17.
Mutations in Alström Protein Impair Terminal Differentiation of Cardiomyocytes
Lincoln T. Shenje, Peter Andersen, Marc K. Halushka, Cecillia Lui, Laviel Fernandez, Gayle B. Collin, Nuria Amat-Alarcon, Wendy Meschino, Ernest Cutz, Kenneth Chang, Raluca Yonescu, Denise A. S. Batista, Yan Chen, Stephen Chelko, Jane E. Crosson, Janet Scheel, Luca Vricella, Brian D. Craig, Beth A. Marosy, David W. Mohr, Kurt N. Hetrick, Jane M. Romm, Alan F. Scott, David Valle, Jürgen K. Naggert, Chulan Kwon, Kimberly F. Doheny, Daniel P. Judge
Nat Commun. Author manuscript; available in PMC 2014 Sep 4.
Published in final edited form as: Nat Commun. 2014; 5: 3416. Published online 2014 Mar 4. doi: 10.1038/ncomms4416
PMCID:
PMC3992616
AbstractArticlePDF–3.2M
18.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
19.
The Alström Syndrome Protein, ALMS1, Interacts with α-Actinin and Components of the Endosome Recycling Pathway
Gayle B. Collin, Jan D. Marshall, Benjamin L. King, Gabriella Milan, Pietro Maffei, Daniel J. Jagger, Jürgen K. Naggert
PLoS One. 2012; 7(5): e37925. Published online 2012 May 31. doi: 10.1371/journal.pone.0037925
PMCID:
PMC3365098
AbstractArticlePDF–1.8M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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