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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 97772882.

KLK6/PAR1 Axis Promotes Tumor Growth and Metastasis by Regulating Cross-Talk between Tumor Cells and Macrophages

Yo Sep Hwang, Hee Jun Cho, Eun Sun Park, Jeewon Lim, Hyang Ran Yoon, Jong-Tae Kim, Suk Ran Yoon, Haiyoung Jung, Yong-Kyung Choe, Yong-Hoon Kim, Chul-Ho Lee, Yong Tae Kwon, Bo Yeon Kim, Hee Gu Lee

Cells. 2022 Dec; 11(24): 4101. Published online 2022 Dec 16. doi: 10.3390/cells11244101

PMCID:: PMC9777288

Abstract Article PDF–3.6M

Select item 87323033.

Blocking Kallikrein 6 Promotes Developmental Myelination

Hyesook Yoon, Erin M. Triplet, Whitney L. Simon, Chan-Il Choi, Laurel S. Kleppe, Elena De Vita, Aubry K. Miller, Isobel A. Scarisbrick

Glia. Author manuscript; available in PMC 2023 Mar 1.

Published in final edited form as: Glia. 2022 Mar; 70(3): 430–450. Published online 2021 Oct 9. doi: 10.1002/glia.24100

PMCID:: PMC8732303

Abstract Article PDF–3.9M

Select item 72600324.

KLK6 expression in skin induces PAR1-mediated psoriasiform dermatitis and inflammatory joint disease

Allison C. Billi, Jessica E. Ludwig, Yi Fritz, Richard Rozic, William R. Swindell, Lam C. Tsoi, Dennis Gruzska, Shahla Abdollahi-Roodsaz, Xianying Xing, Doina Diaconu, Ranjitha Uppala, Maya I. Camhi, Philip A. Klenotic, Mrinal K. Sarkar, M. Elaine Husni, Jose U. Scher, Christine McDonald, J. Michelle Kahlenberg, Ronald J. Midura, Johann E. Gudjonsson, Nicole L. Ward

J Clin Invest. 2020 Jun 1; 130(6): 3151–3157. Published online 2020 May 11. doi: 10.1172/JCI133159

PMCID:: PMC7260032

Abstract Article PDF–12M

Select item 64595105.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 60922056.

Hyesook Yoon, Maja Radulovic, Isobel A. Scarisbrick

Biol Chem. Author manuscript; available in PMC 2018 Sep 25.

Published in final edited form as: Biol Chem. 2018 Sep 25; 399(9): 1041–1052. doi: 10.1515/hsz-2018-0122

PMCID:: PMC6092205

Abstract Article PDF–879K

Select item 54536677.

Hyesook Yoon, Isobel A. Scarisbrick

Biol Chem. Author manuscript; available in PMC 2017 Dec 1.

Published in final edited form as: Biol Chem. 2016 Dec 1; 397(12): 1277–1286. doi: 10.1515/hsz-2016-0239

PMCID:: PMC5453667

Abstract Article PDF–1.0M

Select item 53624218.

KLK6 proteolysis is implicated in the turnover and uptake of extracellular alpha-synuclein species

Georgios Pampalakis, Vasia-Samantha Sykioti, Methodios Ximerakis, Ioanna Stefanakou-Kalakou, Ronald Melki, Kostas Vekrellis, Georgia Sotiropoulou

Oncotarget. 2017 Feb 28; 8(9): 14502–14515. Published online 2016 Nov 10. doi: 10.18632/oncotarget.13264

PMCID:: PMC5362421

Abstract Article PDF–12M

Select item 53424929.

Important role of kallikrein 6 for the development of keratinocyte proliferative resistance to topical glucocorticoids

Mari Kishibe, Gleb Baida, Pankaj Bhalla, Robert M. Lavker, Bethanee Schlosser, Sin Iinuma, Shigetaka Yoshida, Joel T. Dudley, Irina Budunova

Oncotarget. 2016 Oct 25; 7(43): 69479–69488. Published online 2016 Jun 8. doi: 10.18632/oncotarget.9926

PMCID:: PMC5342492

Abstract Article PDF–9.4M

Select item 467427310.

A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity

Vinod Kumar, Jamal-Eddine Bouameur, Janina Bär, Robert H. Rice, Hue-Tran Hornig-Do, Dennis R. Roop, Nicole Schwarz, Susanne Brodesser, Sören Thiering, Rudolf E. Leube, Rudolf J. Wiesner, Preethi Vijayaraj, Christina B. Brazel, Sandra Heller, Hans Binder, Henry Löffler-Wirth, Peter Seibel, Thomas M. Magin

J Cell Biol. 2015 Dec 7; 211(5): 1057–1075. doi: 10.1083/jcb.201404147

Correction in:: J Cell Biol. 2016 Mar 28; 212(7): 877.

PMCID:: PMC4674273

Abstract Article PDF–4.4M

Select item 409718611.

Kallikrein 6 Signals through PAR1 and PAR2 to Promote Neuron Injury and Exacerbate Glutamate Neurotoxicity

Hyesook Yoon, Maja Radulovic, Jianmin Wu, Sachiko I. Blaber, Michael Blaber, Michael G. Fehlings, Isobel A. Scarisbrick

J Neurochem. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: J Neurochem. 2013 Oct; 127(2): 283–298. Published online 2013 May 27. doi: 10.1111/jnc.12293

PMCID:: PMC4097186

Abstract Article PDF–1.5M

Select item 357241012.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 353832513.

Lentivirus Mediated Delivery of Neurosin Promotes Clearance of Wild-type α-Synuclein and Reduces the Pathology in an α-Synuclein Model of LBD

Brian Spencer, Sarah Michael, Jay Shen, Kori Kosberg, Edward Rockenstein, Christina Patrick, Anthony Adame, Eliezer Masliah

Mol Ther. 2013 Jan; 21(1): 31–41. Published online 2012 Apr 17. doi: 10.1038/mt.2012.66

PMCID:: PMC3538325

Abstract Article PDF–1.7M

Select item 333574714.

Kallikrein 6 is a Novel Molecular Trigger of Reactive Astrogliosis

Isobel A. Scarisbrick, Maja Radulovic, Joshua Burda, Nadya Larson, Sachiko I. Blaber, Caterina Giannini, Michael Blaber, Alexander G. Vandell

Biol Chem. Author manuscript; available in PMC 2012 Apr 24.

Published in final edited form as: Biol Chem. 2012 Apr 1; 393(5): 355–367. doi: 10.1515/hsz-2011-0241

PMCID:: PMC3335747

Abstract Article PDF–2.4M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 306547716.

Functional Role of Kallikrein 6 in Regulating Immune Cell Survival

Isobel A. Scarisbrick, Benjamin Epstein, Beth A. Cloud, Hyesook Yoon, Jianmin Wu, Danielle N. Renner, Sachiko I. Blaber, Michael Blaber, Alexander G. Vandell, Alexandra L. Bryson

PLoS One. 2011; 6(3): e18376. Published online 2011 Mar 28. doi: 10.1371/journal.pone.0018376

PMCID:: PMC3065477

Abstract Article PDF–1.4M

Select item 302253417.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 281759918.

ERRγ Regulates Cardiac, Gastric, and Renal Potassium Homeostasis

William A. Alaynick, James M. Way, Stephanie A. Wilson, William G. Benson, Liming Pei, Michael Downes, Ruth Yu, Johan W. Jonker, Jason A. Holt, Deepak K. Rajpal, Hao Li, Joan Stuart, Ruth McPherson, Katja S. Remlinger, Ching-Yi Chang, Donald P. McDonnell, Ronald M. Evans, Andrew N. Billin

Mol Endocrinol. 2010 Feb; 24(2): 299–309. Published online 2009 Dec 4. doi: 10.1210/me.2009-0114

PMCID:: PMC2817599

Abstract Article

Select item 141356819.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086

PMCID:: PMC1413568

Article PDF–99K

Select item 55332320.

Barx2 functions through distinct corepressor classes to regulate hair follicle remodeling

Lorin E. Olson, Jie Zhang, Havilah Taylor, David W. Rose, Michael G. Rosenfeld

Proc Natl Acad Sci U S A. 2005 Mar 8; 102(10): 3708–3713. Published online 2005 Feb 22. doi: 10.1073/pnas.0500519102

PMCID:: PMC553323

Abstract Article PDF–510K

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