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Items: 1 to 20 of 31

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
BOK controls ER proteostasis and physiological ER stress responses in neurons
Franziska Walter, Beatrice D’Orsi, Anagha Jagannathan, Heiko Dussmann, Jochen H. M. Prehn
Front Cell Dev Biol. 2022; 10: 915065. Published online 2022 Aug 15. doi: 10.3389/fcell.2022.915065
PMCID:
PMC9434404
AbstractArticlePDF–3.1M
3.
Some mice lacking intrinsic, as well as death receptor induced apoptosis and necroptosis, can survive to adulthood
Francine F. S. Ke, Kerstin Brinkmann, Anne K. Voss, Andreas Strasser
Cell Death Dis. 2022 Apr; 13(4): 317. Published online 2022 Apr 7. doi: 10.1038/s41419-022-04731-x
PMCID:
PMC8991225
AbstractArticlePDF–1.1M
4.
Loss of BOK Has a Minor Impact on Acetaminophen Overdose-Induced Liver Damage in Mice
Samara Naim, Yuniel Fernandez-Marrero, Simone de Brot, Daniel Bachmann, Thomas Kaufmann
Int J Mol Sci. 2021 Mar; 22(6): 3281. Published online 2021 Mar 23. doi: 10.3390/ijms22063281
PMCID:
PMC8004760
AbstractArticlePDF–2.9M
5.
BOK controls apoptosis by Ca2+ transfer through ER-mitochondrial contact sites
Marcos A. Carpio, Robert E. Means, Allison L. Brill, Alva Sainz, Barbara E. Ehrlich, Samuel G. Katz
Cell Rep. Author manuscript; available in PMC 2021 Mar 26.
Published in final edited form as: Cell Rep. 2021 Mar 9; 34(10): 108827. doi: 10.1016/j.celrep.2021.108827
PMCID:
PMC7995216
AbstractArticlePDF–2.3M
6.
Bok regulates mitochondrial fusion and morphology
Jacqualyn J. Schulman, Laura M. Szczesniak, Eric N. Bunker, Heather A. Nelson, Michael W. Roe, Larry E. Wagner, II, David I. Yule, Richard J. H. Wojcikiewicz
Cell Death Differ. 2019 Dec; 26(12): 2682–2694. Published online 2019 Apr 11. doi: 10.1038/s41418-019-0327-4
PMCID:
PMC7224202
AbstractArticlePDF–4.0M
7.
NMDA Receptor in Vasopressin 1b Neurons Is Not Required for Short-Term Social Memory, Object Memory or Aggression
Sarah K. Williams Avram, Heon-Jin Lee, Jarrett Fastman, Adi Cymerblit-Sabba, Adam Smith, Matthew Vincent, June Song, Michael C. Granovetter, Su-Hyun Lee, Nicholas I. Cilz, Michelle Stackmann, Rahul Chaturvedi, W. Scott Young
Front Behav Neurosci. 2019; 13: 218. Published online 2019 Nov 8. doi: 10.3389/fnbeh.2019.00218
PMCID:
PMC6856057
AbstractArticlePDF–12M
8.
BOK Promotes Erythropoiesis in a Mouse Model of Myelodysplastic Syndrome
Seong-Ho Kang, Oscar Perales, Michael Michuad, Samuel G. Katz
Ann Hematol. Author manuscript; available in PMC 2020 Sep 1.
Published in final edited form as: Ann Hematol. 2019 Sep; 98(9): 2089–2096. Published online 2019 Jun 16. doi: 10.1007/s00277-019-03726-7
PMCID:
PMC6702064
AbstractArticlePDF–1.3M
9.
BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals
Rahul Srivastava, Zhipeng Cao, Christina Nedeva, Samara Naim, Daniel Bachmann, Tatiana Rabachini, Lahiru Gangoda, Sanjay Shahi, Jason Glab, Joseph Menassa, Laura Osellame, Tao Nelson, Yuniel Fernandez-Marrero, Fiona Brown, Andrew Wei, Francine Ke, Lorraine O’Reilly, Marcel Doerflinger, Cody Allison, Andrew Kueh, Rob Ramsay, Brian J. Smith, Suresh Mathivanan, Thomas Kaufmann, Hamsa Puthalakath
Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15469–15474. Published online 2019 Jul 16. doi: 10.1073/pnas.1904523116
PMCID:
PMC6681708
AbstractArticlePDF–1.4M
10.
Bok Is Not Pro-Apoptotic But Suppresses Poly ADP-Ribose Polymerase-Dependent Cell Death Pathways and Protects against Excitotoxic and Seizure-Induced Neuronal Injury
Beatrice D'Orsi, Tobias Engel, Shona Pfeiffer, Saheli Nandi, Thomas Kaufmann, David C. Henshall, Jochen H. M. Prehn
J Neurosci. 2016 Apr 20; 36(16): 4564–4578. doi: 10.1523/JNEUROSCI.3780-15.2016
PMCID:
PMC6601822
AbstractArticlePDF–2.9M
11.
BOK promotes chemical-induced hepatocarcinogenesis in mice
Tatiana Rabachini, Yuniel Fernandez-Marrero, Matteo Montani, Giulio Loforese, Valentina Sladky, Zhaoyue He, Daniel Bachmann, Simone Wicki, Andreas Villunger, Deborah Stroka, Thomas Kaufmann
Cell Death Differ. 2018 Apr; 25(4): 706–718. Published online 2017 Dec 11. doi: 10.1038/s41418-017-0008-0
PMCID:
PMC5864194
AbstractArticlePDF–3.1M
12.
Ceramide-induced BOK promotes mitochondrial fission in preeclampsia
Jonathan Ausman, Joelcio Abbade, Leonardo Ermini, Abby Farrell, Andrea Tagliaferro, Martin Post, Isabella Caniggia
Cell Death Dis. 2018 Mar; 9(3): 298. Published online 2018 Feb 20. doi: 10.1038/s41419-018-0360-0
PMCID:
PMC5833856
AbstractArticlePDF–3.3M
13.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
14.
BOK Is a Non-Canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation
Fabien Llambi, Yue-Ming Wang, Bernadette Victor, Mao Yang, Desiree M. Schneider, Sébastien Gingras, Melissa J. Parsons, Janet H. Zheng, Scott A. Brown, Stéphane Pelletier, Tudor Moldoveanu, Taosheng Chen, Douglas R. Green
Cell. Author manuscript; available in PMC 2017 Apr 7.
Published in final edited form as: Cell. 2016 Apr 7; 165(2): 421–433. Published online 2016 Mar 3. doi: 10.1016/j.cell.2016.02.026
PMCID:
PMC5018360
AbstractArticlePDF–1.6M
15.
The Stability and Expression Level of Bok Are Governed by Binding to Inositol 1,4,5-Trisphosphate Receptors
Jacqualyn J. Schulman, Forrest A. Wright, Xiaobing Han, Eric J. Zluhan, Laura M. Szczesniak, Richard J. H. Wojcikiewicz
J Biol Chem. 2016 May 27; 291(22): 11820–11828. Published online 2016 Apr 6. doi: 10.1074/jbc.M115.711242
PMCID:
PMC4882449
AbstractArticlePDF–1.8M
16.
BCL-2 family member BOK promotes apoptosis in response to endoplasmic reticulum stress
Marcos A. Carpio, Michael Michaud, Wenping Zhou, Jill K. Fisher, Loren D. Walensky, Samuel G. Katz
Proc Natl Acad Sci U S A. 2015 Jun 9; 112(23): 7201–7206. Published online 2015 May 26. doi: 10.1073/pnas.1421063112
PMCID:
PMC4466744
AbstractArticlePDF–2.0M
17.
Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-8 is required for inflammasome priming
Ramanjaneyulu Allam, Kate E Lawlor, Eric Chi-Wang Yu, Alison L Mildenhall, Donia M Moujalled, Rowena S Lewis, Francine Ke, Kylie D Mason, Michael J White, Katryn J Stacey, Andreas Strasser, Lorraine A O’Reilly, Warren Alexander, Benjamin T Kile, David L Vaux, James E Vince
EMBO Rep. 2014 Sep; 15(9): 982–990. Published online 2014 Jul 2. doi: 10.15252/embr.201438463
PMCID:
PMC4198042
AbstractArticlePDF–1.6M
18.
The Bcl-2 Protein Family Member Bok Binds to the Coupling Domain of Inositol 1,4,5-Trisphosphate Receptors and Protects Them from Proteolytic Cleavage
Jacqualyn J. Schulman, Forrest A. Wright, Thomas Kaufmann, Richard J. H. Wojcikiewicz
J Biol Chem. 2013 Aug 30; 288(35): 25340–25349. Published online 2013 Jul 24. doi: 10.1074/jbc.M113.496570
PMCID:
PMC3757198
AbstractArticlePDF–2.5M
19.
Consequences of the combined loss of BOK and BAK or BOK and BAX
F Ke, P Bouillet, T Kaufmann, A Strasser, J Kerr, A K Voss
Cell Death Dis. 2013 Jun; 4(6): e650. Published online 2013 Jun 6. doi: 10.1038/cddis.2013.176
PMCID:
PMC3698543
AbstractArticlePDF–2.5M
20.
Intracellular localization of the BCL-2 family member BOK and functional implications
N Echeverry, D Bachmann, F Ke, A Strasser, H U Simon, T Kaufmann
Cell Death Differ. 2013 Jun; 20(6): 785–799. Published online 2013 Feb 22. doi: 10.1038/cdd.2013.10
PMCID:
PMC3647236
AbstractArticlePDF–3.4M

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