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Select item 112885041.

p53 governs an AT1 differentiation programme in lung cancer suppression

Alyssa M. Kaiser, Alberto Gatto, Kathryn J. Hanson, Richard L. Zhao, Nitin Raj, Michael G. Ozawa, José A. Seoane, Kathryn T. Bieging-Rolett, Mengxiong Wang, Irene Li, Winston L. Trope, Douglas Z. Liou, Joseph B. Shrager, Sylvia K. Plevritis, Aaron M. Newman, Capucine Van Rechem, Laura D. Attardi

Nature. Author manuscript; available in PMC 2024 Jul 30.

Published in final edited form as: Nature. 2023 Jul; 619(7971): 851–859. Published online 2023 Jul 19. doi: 10.1038/s41586-023-06253-8

PMCID:: PMC11288504

Abstract Article PDF–7.4M

Select item 112665632.

Prenatal exposure to Benzo[a]pyrene affects maternal–fetal outcomes via placental apoptosis

Nan Zhao, Jun Chu, Jieying Liu, Liangkun Ma, Ning Ma, Wei Song, Tianshu Sun

Sci Rep. 2024; 14: 17002. Published online 2024 Jul 24. doi: 10.1038/s41598-024-68029-y

PMCID:: PMC11266563

Abstract Article PDF–2.8M

Select item 112339223.

Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication

Shengli Ming, Shijun Zhang, Jiayou Xing, Guoyu Yang, Lei Zeng, Jiang Wang, Beibei Chu

iScience. 2024 Jul 19; 27(7): 110144. Published online 2024 Jun 4. doi: 10.1016/j.isci.2024.110144

PMCID:: PMC11233922

Abstract Article PDF–7.4M

Select item 112168954.

CRACD Loss Induces Neuroendocrine Cell Plasticity of Lung Adenocarcinoma

Bongjun Kim, Shengzhe Zhang, Yuanjian Huang, Kyung-Pil Ko, Youn-Sang Jung, Jinho Jang, Gengyi Zou, Jie Zhang, Sohee Jun, Kee-Beom Kim, Kwon-Sik Park, Jae-Il Park

Cell Rep. Author manuscript; available in PMC 2024 Jul 2.

Published in final edited form as: Cell Rep. 2024 Jun 25; 43(6): 114286. Published online 2024 May 25. doi: 10.1016/j.celrep.2024.114286

PMCID:: PMC11216895

Abstract Article PDF–2.9M

Select item 111940145.

The Janus kinase 1 is critical for pancreatic cancer initiation and progression

Hridaya Shrestha, Patrick D. Rädler, Rayane Dennaoui, Madison N. Wicker, Nirakar Rajbhandari, Yunguang Sun, Amy R. Peck, Kerry Vistisen, Aleata A. Triplett, Rafic Beydoun, Esta Sterneck, Dieter Saur, Hallgeir Rui, Kay-Uwe Wagner

Cell Rep. Author manuscript; available in PMC 2024 Jun 23.

Published in final edited form as: Cell Rep. 2024 May 28; 43(5): 114202. Published online 2024 May 10. doi: 10.1016/j.celrep.2024.114202

PMCID:: PMC11194014

Abstract Article PDF–3.3M

Select item 111899116.

Differential extracellular vesicle concentration and their biomarker expression of integrin α_v/β₅, EpCAM, and glypican-1 in pancreatic cancer models

Reed Jacobson, Sangdeuk Ha, Sakurako Tani, Shrinwanti Ghosh, Yagna P. R. Jarajapu, Randall E. Brand, Jiha Kim, Yongki Choi

Sci Rep. 2024; 14: 14273. Published online 2024 Jun 20. doi: 10.1038/s41598-024-65209-8

PMCID:: PMC11189911

Abstract Article PDF–1.2M

Select item 111892337.

Revisiting the NPcis mouse model: A new tool to model plexiform neurofibroma

Camille Plante, Teddy Mohamad, Dhanushka Hewa Bostanthirige, Michel Renaud, Harsimran Sidhu, Michel ElChoueiry, Jean-Paul Sabo Vatasescu, Mikael Poirier, Sameh Geha, Jean-Philippe Brosseau

PLoS One. 2024; 19(6): e0301040. Published online 2024 Jun 20. doi: 10.1371/journal.pone.0301040

PMCID:: PMC11189233

Abstract Article PDF–3.5M

Select item 111765778.

Trefoil factor 1 suppresses stemness and enhances chemosensitivity of pancreatic cancer

Junpei Yamaguchi, Toshio Kokuryo, Yukihiro Yokoyama, Shunsuke Oishi, Masaki Sunagawa, Takashi Mizuno, Shunsuke Onoe, Nobuyuki Watanabe, Atsushi Ogura, Tomoki Ebata

Cancer Med. 2024 Jun; 13(11): e7395. Published online 2024 Jun 13. doi: 10.1002/cam4.7395

PMCID:: PMC11176577

Abstract Article PDF–17M

Select item 111666589.

iPS cell generation-associated point mutations include many C > T substitutions via different cytosine modification mechanisms

Ryoko Araki, Tomo Suga, Yuko Hoki, Kaori Imadome, Misato Sunayama, Satoshi Kamimura, Mayumi Fujita, Masumi Abe

Nat Commun. 2024; 15: 4946. Published online 2024 Jun 11. doi: 10.1038/s41467-024-49335-5

PMCID:: PMC11166658

Abstract Article PDF–1.8M

Select item 1116639710.

A NOVEL P53-DEPENDENT APOPTOSIS FUNCTION OF TARSH IN TUMOR DEVELOPMENT

TAKESHI WAKOH, MASATAKA SUGIMOTO, KUNIHIKO TERAUCHI, JUN-ICHI SHIMADA, MITSUO MARUYAMA

Nagoya J Med Sci. 2009 Aug; 71(3-4): 109–114.

PMCID:: PMC11166397

Abstract Article PDF–1.0M

Select item 1116000511.

In vitro differentiation of Runx3^−/–p53^−/– gastric epithelial cells into intestinal type cells

Hiroshi Fukamachi, Ayako Mimata, Issei Tanaka, Kosei Ito, Yoshiaki Ito, Yasuhito Yuasa

Cancer Sci. 2008 Apr; 99(4): 671–676. Published online 2008 Mar 3. doi: 10.1111/j.1349-7006.2008.00732.x

PMCID:: PMC11160005

Abstract Article PDF–1.8M

Select item 1115526412.

Lineage-specific intolerance to oncogenic drivers restricts histological transformation

Eric E. Gardner, Ethan M. Earlie, Kate Li, Jerin Thomas, Melissa J. Hubisz, Benjamin D. Stein, Chen Zhang, Lewis C. Cantley, Ashley M. Laughney, Harold Varmus

Science. Author manuscript; available in PMC 2024 Jun 6.

Published in final edited form as: Science. 2024 Feb 9; 383(6683): eadj1415. Published online 2024 Feb 9. doi: 10.1126/science.adj1415

PMCID:: PMC11155264

Abstract Article PDF–2.7M

Select item 1114880013.

Age-specific induction of mutant p53 drives clonal hematopoiesis and acute myeloid leukemia in adult mice

Rasoul Pourebrahim, Rafael Heinz Montoya, Hiroki Akiyama, Lauren Ostermann, Shayuan Khazaei, Muharrem Muftuoglu, Natalia Baran, Ran Zhao, Tom Lesluyes, Bin Liu, Joseph D. Khoury, Mihai Gagea, Peter Van Loo, Michael Andreeff

Cell Rep Med. 2024 May 21; 5(5): 101558. Published online 2024 May 10. doi: 10.1016/j.xcrm.2024.101558

PMCID:: PMC11148800

Abstract Article PDF–9.3M

Select item 1114686414.

The role of p53 in tumour suppression: lessons from mouse models

L. D. Attardi, T. Jacks

Cell Mol Life Sci. 1999 Jan; 55(1): 48–63. Published online 2014 Feb 6. doi: 10.1007/s000180050269

PMCID:: PMC11146864

Abstract PDF–270K

Select item 1114679615.

p53 in embryonic development: maintaining a fine balance

J. Choi, L. A. Donehower

Cell Mol Life Sci. 1999 Jan; 55(1): 38–47. Published online 2014 Feb 6. doi: 10.1007/s000180050268

PMCID:: PMC11146796

Abstract PDF–162K

Select item 1114193516.

Blocking the angiopoietin-2–dependent integrin β-1 signaling axis abrogates small cell lung cancer invasion and metastasis

Lydia Meder, Charlotte Isabelle Orschel, Christoph Julius Otto, Mirjam Koker, Johannes Brägelmann, Meryem S. Ercanoglu, Sabrina Dähling, Anik Compes, Carolin Selenz, Marieke Nill, Felix Dietlein, Alexandra Florin, Marie-Lisa Eich, Sven Borchmann, Margarete Odenthal, Raquel Blazquez, Frank Hilberg, Florian Klein, Michael Hallek, Reinhard Büttner, H. Christian Reinhardt, Roland T. Ullrich

JCI Insight. 2024 May 22; 9(10): e166402. Published online 2024 May 22. doi: 10.1172/jci.insight.166402

PMCID:: PMC11141935

Abstract Article PDF–6.7M

Select item 1113989317.

Statin prevents cancer development in chronic inflammation by blocking interleukin 33 expression

Jong Ho Park, Mahsa Mortaja, Heehwa G. Son, Xutu Zhao, Lauren M. Sloat, Marjan Azin, Jun Wang, Michael R. Collier, Krishna S. Tummala, Anna Mandinova, Nabeel Bardeesy, Yevgeniy R. Semenov, Mari Mino-Kenudson, Shadmehr Demehri

Nat Commun. 2024; 15: 4099. Published online 2024 May 30. doi: 10.1038/s41467-024-48441-8

PMCID:: PMC11139893

Abstract Article PDF–2.6M

Select item 1113612818.

Retinoblastoma family proteins: insights gained through genetic manipulation of mice

K. A. Wikenheiser-Brokamp

Cell Mol Life Sci. 2006 Apr; 63(7-8): 767–780. Published online 2006 Feb 7. doi: 10.1007/s00018-005-5487-3

PMCID:: PMC11136128

Abstract Article PDF–227K

Select item 1111763419.

Palmitic Acid Exerts Anti-Tumorigenic Activities by Modulating Cellular Stress and Lipid Droplet Formation in Endometrial Cancer

Ziyi Zhao, Jiandong Wang, Weimin Kong, Meredith A. Newton, Wesley C. Burkett, Wenchuan Sun, Lindsey Buckingham, Jillian O’Donnell, Hongyan Suo, Boer Deng, Xiaochang Shen, Xin Zhang, Tianran Hao, Chunxiao Zhou, Victoria L. Bae-Jump

Biomolecules. 2024 May; 14(5): 601. Published online 2024 May 20. doi: 10.3390/biom14050601

PMCID:: PMC11117634

Abstract Article PDF–11M

Select item 1110056520.

Ketogenic diet induces p53-dependent cellular senescence in multiple organs

Sung-Jen Wei, Joseph R. Schell, E. Sandra Chocron, Mahboubeh Varmazyad, Guogang Xu, Wan Hsi Chen, Gloria M. Martinez, Felix F. Dong, Prethish Sreenivas, Rolando Trevino, Jr., Haiyan Jiang, Yan Du, Afaf Saliba, Wei Qian, Brandon Lorenzana, Alia Nazarullah, Jenny Chang, Kumar Sharma, Erin Munkácsy, Nobuo Horikoshi, David Gius

Sci Adv. 2024 May 17; 10(20): eado1463. Published online 2024 May 17. doi: 10.1126/sciadv.ado1463

PMCID:: PMC11100565

Abstract Article PDF–11M

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