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Items: 1 to 20 of 30

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Discoveries of GPR39 as an evolutionarily conserved receptor for bile acids and of its involvement in biliary acute pancreatitis
Zhentao Zi, Yi Rao
Sci Adv. 2024 Feb 2; 10(5): eadj0146. Published online 2024 Feb 2. doi: 10.1126/sciadv.adj0146
PMCID:
PMC10836733
AbstractArticlePDF–2.2M
3.
GPR39 regulated spinal glycinergic inhibition and mechanical inflammatory pain
Hu-Hu Bai, Kang-Li Wang, Xiang-Ru Zeng, Jing Li, Yuan Li, Jia-Yu Xu, Yue Zhang, Hai-Feng Jiang, Xian Yang, Zhan-Wei Suo, Xiao-Dong Hu
Sci Adv. 2024 Feb 2; 10(5): eadj3808. Published online 2024 Feb 2. doi: 10.1126/sciadv.adj3808
PMCID:
PMC10836721
AbstractArticlePDF–8.3M
4.
GPR39 Knockout Worsens Microcirculatory Response to Experimental Stroke in a Sex-Dependent Manner
Yifan Xu, Wenri H. Zhang, Elyse M. Allen, Lev M. Fedorov, Anthony P. Barnes, Zu Yuan Qian, Thierno Madjou Bah, Yuandong Li, Ruikang K. Wang, Robert E. Shangraw, Nabil J. Alkayed
Transl Stroke Res. Author manuscript; available in PMC 2024 Oct 1.
Published in final edited form as: Transl Stroke Res. 2023 Oct; 14(5): 766–775. Published online 2022 Oct 1. doi: 10.1007/s12975-022-01093-6
PMCID:
PMC10065946
AbstractArticlePDF–734K
5.
Inhibition of GPR39 restores defects in endothelial cell–mediated neovascularization under the duress of chronic hyperglycemia: Evidence for regulatory roles of the sonic hedgehog signaling axis
Sai Pranathi Meda Venkata, Hainan Li, Liping Xu, Jia Yi Koh, Huong Nguyen, Morgan Minjares, Chunying Li, Anjaneyulu Kowluru, Graeme Milligan, Jie-Mei Wang
Proc Natl Acad Sci U S A. 2023 Jan 3; 120(1): e2208541120. Published online 2022 Dec 27. doi: 10.1073/pnas.2208541120
PMCID:
PMC9910611
AbstractArticlePDF–8.3M
6.
GPR39 Deficiency Impairs Memory and Alters Oxylipins and Inflammatory Cytokines Without Affecting Cerebral Blood Flow in a High-Fat Diet Mouse Model of Cognitive Impairment
Thierno M. Bah, Elyse M. Allen, Manuel Garcia-Jaramillo, Ruby Perez, Yalda Zarnegarnia, Catherine M. Davis, Madeline B. Bloom, Armando A. Magana, Jaewoo Choi, Gerd Bobe, Martin M. Pike, Jacob Raber, Claudia S. Maier, Nabil J. Alkayed
Front Cell Neurosci. 2022; 16: 893030. Published online 2022 Jul 6. doi: 10.3389/fncel.2022.893030
PMCID:
PMC9298837
AbstractArticlePDF–9.1M
7.
Control of coronary vascular resistance by eicosanoids via a novel GPCR
Nabil J. Alkayed, Zhiping Cao, Zu Yuan Qian, Shanthi Nagarajan, Xuehong Liu, Jonathan W. Nelson, Fuchun Xie, Bingbing Li, Wei Fan, Lijuan Liu, Marjorie R. Grafe, Catherine M. Davis, Xiangshu Xiao, Anthony P. Barnes, Sanjiv Kaul
Am J Physiol Cell Physiol. 2022 May 1; 322(5): C1011–C1021. Published online 2022 Apr 6. doi: 10.1152/ajpcell.00454.2021
Correction in:
Am J Physiol Cell Physiol. 2022 Jun 1; 322(6): C1270.
PMCID:
PMC9255704
AbstractArticle
8.
Activation of the zinc-sensing receptor GPR39 promotes T-cell reconstitution after hematopoietic cell transplant in mice
Lorenzo Iovino, Kirsten Cooper, Paul deRoos, Sinéad Kinsella, Cindy Evandy, Tamas Ugrai, Francesco Mazziotta, Kathleen S. Ensbey, David Granadier, Kayla Hopwo, Colton Smith, Alex Gagnon, Sara Galimberti, Mario Petrini, Geoffrey R. Hill, Jarrod A. Dudakov
Blood. 2022 Jun 23; 139(25): 3655–3666. doi: 10.1182/blood.2021013950
PMCID:
PMC9227099
AbstractArticle
9.
G protein-coupled receptor 39 activation alleviates oxidized low-density lipoprotein-induced macrophage inflammatory response, lipid accumulation and apoptosis by inducing A20 expression
Lu Chen, Zhengdong Fang, Xiaotian Wang, Xiaojie Sun, Xinbao Ge, Can Cheng, Hejie Hu
Bioengineered. 2021; 12(1): 4070–4080. Published online 2021 Jul 21. doi: 10.1080/21655979.2021.1952917
PMCID:
PMC8806696
AbstractArticlePDF–2.5M
10.
Selective release of gastrointestinal hormones induced by an orally active GPR39 agonist
Kaare V. Grunddal, Thi A. Diep, Natalia Petersen, Iain R. Tough, Louise J. Skov, Lingzhi Liu, Jesse A. Buijink, Franziska Mende, Chunyu Jin, Sara L. Jepsen, Louis M.E. Sørensen, Michael P. Achiam, Rune B. Strandby, Anders Bach, Bolette Hartmann, Thomas M. Frimurer, Siv A. Hjorth, Michel Bouvier, Helen Cox, Birgitte Holst
Mol Metab. 2021 Jul; 49: 101207. Published online 2021 Mar 9. doi: 10.1016/j.molmet.2021.101207
PMCID:
PMC8042403
AbstractArticlePDF–1.8M
11.
Mast cells play role in wound healing through the ZnT2/GPR39/IL-6 axis
Keigo Nishida, Aiko Hasegawa, Satoru Yamasaki, Ryota Uchida, Wakana Ohashi, Yosuke Kurashima, Jun Kunisawa, Shunsuke Kimura, Toshihiko Iwanaga, Hiroshi Watarai, Koji Hase, Hideki Ogura, Manabu Nakayama, Jun-ichi Kashiwakura, Yoshimichi Okayama, Masato Kubo, Osamu Ohara, Hiroshi Kiyono, Haruhiko Koseki, Masaaki Murakami, Toshio Hirano
Sci Rep. 2019; 9: 10842. Published online 2019 Jul 25. doi: 10.1038/s41598-019-47132-5
PMCID:
PMC6658492
AbstractArticlePDF–1.9M
12.
The Zn2+-sensing receptor, ZnR/GPR39, upregulates colonocytic Cl− absorption, via basolateral KCC1, and reduces fluid loss
Laxmi Sunuwar, Hila Asraf, Mark Donowitz, Israel Sekler, Michal Hershfinkel
Biochim Biophys Acta. Author manuscript; available in PMC 2017 Aug 15.
Published in final edited form as: Biochim Biophys Acta. 2017 Apr; 1863(4): 947–960. Published online 2017 Jan 16. doi: 10.1016/j.bbadis.2017.01.009
PMCID:
PMC5557417
AbstractArticlePDF–2.8M
13.
Obestatin Induction of Early-Response Gene Expression in Gastrointestinal and Adipose Tissues and the Mediatory Role of G Protein-Coupled Receptor, GPR39
Jian V. Zhang, Holger Jahr, Chin-Wei Luo, Cynthia Klein, Kristof Van Kolen, Luc Ver Donck, Ananya De, Esther Baart, Jing Li, Dieder Moechars, Aaron J. W. Hsueh
Mol Endocrinol. June 1, 2008; 22(6): 1464–1475. doi: 10.1210/me.2007-0569
PMCID:
PMC5419543
AbstractArticle
14.
The zinc sensing receptor, ZnR/GPR39, triggers metabotropic calcium signalling in colonocytes and regulates occludin recovery in experimental colitis
Laxmi Sunuwar, Michal Medini, Limor Cohen, Israel Sekler, Michal Hershfinkel
Philos Trans R Soc Lond B Biol Sci. 2016 Aug 5; 371(1700): 20150420. doi: 10.1098/rstb.2015.0420
Correction in:
Philos Trans R Soc Lond B Biol Sci. 2016 Sep 19; 371(1703): 20160331.
PMCID:
PMC4938021
AbstractArticlePDF–1.4M
15.
The zinc sensing receptor, ZnR/GPR39, controls proliferation and differentiation of colonocytes and thereby tight junction formation in the colon
L Cohen, I Sekler, M Hershfinkel
Cell Death Dis. 2014 Jun; 5(6): e1307. Published online 2014 Jun 26. doi: 10.1038/cddis.2014.262
PMCID:
PMC4611734
AbstractArticlePDF–1.8M
16.
HOMEOSTATIC REGULATION OF KCC2 ACTIVITY BY THE ZINC RECEPTOR mZnR/GPR39 DURING SEIZURES
David Gilad, Sharon Shorer, Maya Ketzef, Alon Friedman, Israel Sekler, Elias Aizenman, Michal Hershfinkel
Neurobiol Dis. Author manuscript; available in PMC 2016 Sep 1.
Published in final edited form as: Neurobiol Dis. 2015 Sep; 81: 4–13. Published online 2015 Jan 3. doi: 10.1016/j.nbd.2014.12.020
PMCID:
PMC4490144
AbstractArticlePDF–1.4M
17.
GPR39 (Zinc Receptor) Knockout Mice Exhibit Depression-Like Behavior and CREB/BDNF Down-Regulation in the Hippocampus
Katarzyna Młyniec, Bogusława Budziszewska, Birgitte Holst, Beata Ostachowicz, Gabriel Nowak
Int J Neuropsychopharmacol. 2015 Feb; 18(3): pyu002. Published online 2015 Jan 17. doi: 10.1093/ijnp/pyu002
PMCID:
PMC4360246
AbstractArticlePDF–767K
18.
GPR39 marks specific cells within the sebaceous gland and contributes to skin wound healing
Huashan Zhao, Jingqiao Qiao, Shoubing Zhang, Huishan Zhang, Xiaohua Lei, Xinyue Wang, Zhili Deng, Lina Ning, Yujing Cao, Yong Guo, Shuang Liu, Enkui Duan
Sci Rep. 2015; 5: 7913. Published online 2015 Jan 21. doi: 10.1038/srep07913
PMCID:
PMC4300488
AbstractArticlePDF–13M
19.
GPR39 Is Coupled to TMEM16A in Intestinal Fibroblast-Like Cells
Fanning Zeng, Nicholas Wind, Conor Mcclenaghan, J. Martin Verkuyl, Robert P. Watson, Mark S. Nash
PLoS One. 2012; 7(10): e47686. Published online 2012 Oct 25. doi: 10.1371/journal.pone.0047686
PMCID:
PMC3485058
AbstractArticlePDF–3.2M
20.
SNARE-dependent upregulation of KCC2 activity following metabotropic zinc receptor (mZnR/GPR39) activation in rat cortical neurons in vitro
Robert A. Saadi, Kai He, Karen A. Hartnett, Karl Kandler, Michal Hershfinkel, Elias Aizenman
Neuroscience. Author manuscript; available in PMC 2013 May 17.
Published in final edited form as: Neuroscience. 2012 May 17; 210: 38–46. Published online 2012 Mar 7. doi: 10.1016/j.neuroscience.2012.03.001
PMCID:
PMC3358579
AbstractArticlePDF–1.5M

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