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Items: 1 to 20 of 29

1.
Thymidine Phosphorylase Deficiency or Inhibition Preserves Cardiac Function in Mice With Acute Myocardial Infarction
Lili Du, Hong Yue, Boyd R. Rorabaugh, Oliver Q. Y. Li, Autumn R. DeHart, Gretel Toloza‐Alvarez, Liang Hong, James Denvir, Ellen Thompson, Wei Li
J Am Heart Assoc. 2023 Apr 4; 12(7): e028023. Published online 2023 Mar 28. doi: 10.1161/JAHA.122.028023
PMCID:
PMC10122909
AbstractArticlePDF–11M
2.
Targeting Thymidine Phosphorylase with Tipiracil Hydrochloride Attenuates Thrombosis without Increasing Risk of Bleeding in Mice
Adam Belcher, Abu Hasanat Md Zulfiker, Oliver Qiyue Li, Hong Yue, Anirban Sen Gupta, Wei Li
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2022 Feb 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2021 Feb; 41(2): 668–682. Published online 2020 Dec 10. doi: 10.1161/ATVBAHA.120.315109
PMCID:
PMC8105268
AbstractArticlePDF–3.1M
3.
Paracrine stimulation of endothelial cell motility and angiogenesis by platelet-derived deoxyribose-1-phosphate: Platelets stimulate endothelial cell migration
Giordano Pula, Elena Garonna, Warwick B Dunn, Michio Hirano, Giuseppe Pizzorno, Michelangelo Campanella, Edward L Schwartz, Mahmoud H el Kouni, Caroline PD Wheeler-Jones
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2010 Dec; 30(12): 2631–2638. Published online 2010 Sep 30. doi: 10.1161/ATVBAHA.110.215855
PMCID:
PMC7528120
AbstractArticlePDF–1.4M
4.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
5.
Administration of deoxyribonucleosides or inhibition of their catabolism as a pharmacological approach for mitochondrial DNA depletion syndrome
Yolanda Cámara, Emiliano González-Vioque, Mauro Scarpelli, Javier Torres-Torronteras, Andrea Caballero, Michio Hirano, Ramon Martí
Hum Mol Genet. 2014 May 1; 23(9): 2459–2467. Published online 2013 Dec 20. doi: 10.1093/hmg/ddt641
PMCID:
PMC6281351
AbstractArticlePDF–464K
6.
Sco2 Deficient Mice Develop Increased Adiposity and Insulin Resistance
Shauna Hill, Sathyaseelan S Deepa, Kavithalakshmi Sataranatarajan, Pavithra Premkumar, Daniel Pulliam, Yuhong Liu, Vanessa Y. Soto, Kathleen E. Fischer, Holly Van Remmen
Mol Cell Endocrinol. Author manuscript; available in PMC 2018 Nov 5.
Published in final edited form as: Mol Cell Endocrinol. 2017 Nov 5; 455: 103–114. Published online 2017 Apr 18. doi: 10.1016/j.mce.2017.03.019
PMCID:
PMC5592144
AbstractArticlePDF–3.7M
7.
SCO2 mediates oxidative stress-induced glycolysis to OXPHOS switch in hematopoietic stem cells
Wei Du, Surya Amarachintha, Andrew F. Wilson, Qishen Pang
Stem Cells. Author manuscript; available in PMC 2017 Apr 1.
Published in final edited form as: Stem Cells. 2016 Apr; 34(4): 960–971. Published online 2015 Dec 31. doi: 10.1002/stem.2260
PMCID:
PMC4838537
AbstractArticlePDF–1.7M
8.
Mitochondrial iron chelation ameliorates cigarette-smoke induced bronchitis and emphysema in mice
Suzanne M. Cloonan, Kimberly Glass, Maria E. Laucho-Contreras, Abhiram R. Bhashyam, Morgan Cervo, Maria A. Pabón, Csaba Konrad, Francesca Polverino, Ilias I. Siempos, Elizabeth Perez, Kenji Mizumura, Manik C. Ghosh, Harikrishnan Parameswaran, Niamh C. Williams, Kristen T. Rooney, Zhi-Hua Chen, Monica P. Goldklang, Guo-Cheng Yuan, Stephen C. Moore, Dawn L. Demeo, Tracey A. Rouault, Jeanine M. D’Armiento, Eric A. Schon, Giovanni Manfredi, John Quackenbush, Ashfaq Mahmood, Edwin K. Silverman, Caroline A. Owen, Augustine M.K. Choi
Nat Med. Author manuscript; available in PMC 2016 Aug 1.
Published in final edited form as: Nat Med. 2016 Feb; 22(2): 163–174. Published online 2016 Jan 11. doi: 10.1038/nm.4021
PMCID:
PMC4742374
AbstractArticlePDF–1.1M
9.
Astrocytic TYMP and VEGFA drive blood–brain barrier opening in inflammatory central nervous system lesions
Candice Chapouly, Azeb Tadesse Argaw, Sam Horng, Kamilah Castro, Jingya Zhang, Linnea Asp, Hannah Loo, Benjamin M. Laitman, John N. Mariani, Rebecca Straus Farber, Elena Zaslavsky, German Nudelman, Cedric S. Raine, Gareth R. John
Brain. 2015 Jun; 138(6): 1548–1567. Published online 2015 Mar 22. doi: 10.1093/brain/awv077
PMCID:
PMC4614128
AbstractArticlePDF–2.8M
10.
Cardiac deficiency of single cytochrome oxidase assembly factor scox induces p53-dependent apoptosis in a Drosophila cardiomyopathy model
Leticia Martínez-Morentin, Lidia Martínez, Sarah Piloto, Hua Yang, Eric A. Schon, Rafael Garesse, Rolf Bodmer, Karen Ocorr, Margarita Cervera, Juan J. Arredondo
Hum Mol Genet. 2015 Jul 1; 24(13): 3608–3622. Published online 2015 Mar 19. doi: 10.1093/hmg/ddv106
PMCID:
PMC4459388
AbstractArticlePDF–1.5M
11.
Thymidine Phosphorylase Participates in Platelet Signaling and Promotes Thrombosis
Wei Li, Alba Gigante, Maria-Jesus Perez-Perez, Hong Yue, Michio Hirano, Thomas McIntyre, Roy L Silverstein
Circ Res. Author manuscript; available in PMC 2015 Dec 5.
Published in final edited form as: Circ Res. 2014 Dec 5; 115(12): 997–1006. Published online 2014 Oct 6. doi: 10.1161/CIRCRESAHA.115.304591
PMCID:
PMC4258140
AbstractArticlePDF–2.2M
12.
NAD+-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease
Raffaele Cerutti, Eija Pirinen, Costanza Lamperti, Silvia Marchet, Anthony A. Sauve, Wei Li, Valerio Leoni, Eric A. Schon, Françoise Dantzer, Johan Auwerx, Carlo Viscomi, Massimo Zeviani
Cell Metab. 2014 Jun 3; 19(6): 1042–1049. doi: 10.1016/j.cmet.2014.04.001
PMCID:
PMC4051987
AbstractArticle
13.
A novel structural mechanism for redox regulation of uridine phosphorylase 2 activity
Tarmo P. Roosild, Samantha Castronovo, Adelbert Villoso, Amy Ziemba, Giuseppe Pizzorno
J Struct Biol. Author manuscript; available in PMC 2012 Nov 1.
Published in final edited form as: J Struct Biol. 2011 Nov; 176(2): 229–237. Published online 2011 Aug 10. doi: 10.1016/j.jsb.2011.08.002
PMCID:
PMC3190963
AbstractArticlePDF–1.0M
14.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
15.
Physical Exercise Regulates p53 Activity Targeting SCO2 and Increases Mitochondrial COX Biogenesis in Cardiac Muscle with Age
Zhengtang Qi, Jie He, Yuhui Su, Qiang He, Jingxia Liu, Lu Yu, Omar Al-Attas, Tajamul Hussain, Shuzhe Ding, Liu Ji, Min Qian
PLoS One. 2011; 6(7): e21140. Published online 2011 Jul 7. doi: 10.1371/journal.pone.0021140
PMCID:
PMC3131270
AbstractArticlePDF–825K
16.
In Vivo Correction of COX Deficiency by Activation of the AMPK/PGC-1α Axis
Carlo Viscomi, Emanuela Bottani, Gabriele Civiletto, Raffaele Cerutti, Maurizio Moggio, Gigliola Fagiolari, Eric A. Schon, Costanza Lamperti, Massimo Zeviani
Cell Metab. 2011 Jul 6; 14(1): 80–90. doi: 10.1016/j.cmet.2011.04.011
PMCID:
PMC3130927
AbstractArticle
17.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
18.
Unexpected Vascular Enrichment of SCO1 over SCO2 in Mammalian Tissues : Implications for Human Mitochondrial Disease
Sonja Brosel, Hua Yang, Kurenai Tanji, Eduardo Bonilla, Eric A. Schon
Am J Pathol. 2010 Nov; 177(5): 2541–2548. doi: 10.2353/ajpath.2010.100229
PMCID:
PMC2966810
AbstractArticlePDF–2.4M
19.
Analysis of mouse models of cytochrome c oxidase deficiency owing to mutations in Sco2
Hua Yang, Sonja Brosel, Rebeca Acin-Perez, Vesna Slavkovich, Ichizo Nishino, Raffay Khan, Ira J. Goldberg, Joseph Graziano, Giovanni Manfredi, Eric A. Schon
Hum Mol Genet. 2010 Jan 1; 19(1): 170–180. Published online 2009 Oct 16. doi: 10.1093/hmg/ddp477
PMCID:
PMC2792155
AbstractArticlePDF–498K
20.
Unbalanced deoxynucleotide pools cause mitochondrial DNA instability in thymidine phosphorylase-deficient mice
Luis C. López, Hasan O. Akman, Ángeles García-Cazorla, Beatriz Dorado, Ramón Martí, Ichizo Nishino, Saba Tadesse, Giuseppe Pizzorno, Dikoma Shungu, Eduardo Bonilla, Kurenai Tanji, Michio Hirano
Hum Mol Genet. 2009 Feb 15; 18(4): 714–722. Published online 2008 Nov 21. doi: 10.1093/hmg/ddn401
PMCID:
PMC2638828
AbstractArticlePDF–290K

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