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Select item 109600371.

Rab4A-directed endosome traffic shapes pro-inflammatory mitochondrial metabolism in T cells via mitophagy, CD98 expression, and kynurenine-sensitive mTOR activation

Nick Huang, Thomas Winans, Brandon Wyman, Zachary Oaks, Tamas Faludi, Gourav Choudhary, Zhi-Wei Lai, Joshua Lewis, Miguel Beckford, Manuel Duarte, Daniel Krakko, Akshay Patel, Joy Park, Tiffany Caza, Mahsa Sadeghzadeh, Laurence Morel, Mark Haas, Frank Middleton, Katalin Banki, Andras Perl

Nat Commun. 2024; 15: 2598. Published online 2024 Mar 22. doi: 10.1038/s41467-024-46441-2

PMCID:: PMC10960037

Abstract Article PDF–5.9M

Select item 107693502.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 106702913.

ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment

Jiawen Xiang, Anthony J. Pompetti, Adam P. Faranda, Yan Wang, Samuel G. Novo, David Wan-Cheng Li, Melinda K. Duncan

Cells. 2023 Nov; 12(22): 2636. Published online 2023 Nov 16. doi: 10.3390/cells12222636

PMCID:: PMC10670291

Abstract Article PDF–9.2M

Select item 105266764.

Metabolite Neu5Ac triggers SLC3A2 degradation promoting vascular endothelial ferroptosis and aggravates atherosclerosis progression in ApoE^-/-mice

Peng Xiang, Qingqiu Chen, Le Chen, Jin Lei, Zhiyi Yuan, Hui Hu, Yining Lu, Xianmin Wang, Tingting Wang, Ruihong Yu, Wanping Zhang, Jun Zhang, Chao Yu, Limei Ma

Theranostics. 2023; 13(14): 4993–5016. Published online 2023 Sep 4. doi: 10.7150/thno.87968

PMCID:: PMC10526676

Abstract Article PDF–13M

Select item 103078525.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Abstract Article PDF–8.8M

Select item 99382166.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Abstract Article PDF–5.3M

Select item 98492997.

Protein Expression of Amino Acid Transporters Is Altered in Isolated Cerebral Microvessels of 5xFAD Mouse Model of Alzheimer’s Disease

Elena Puris, Liudmila Saveleva, Izaque de Sousa Maciel, Katja M. Kanninen, Seppo Auriola, Gert Fricker

Mol Neurobiol. 2023; 60(2): 732–748. Published online 2022 Nov 11. doi: 10.1007/s12035-022-03111-y

PMCID:: PMC9849299

Abstract Article PDF–2.3M

Select item 97945548.

SLC3A2 and SLC7A2 Mediate the Exogenous Putrescine-Induced Adipocyte Differentiation

Jin Eom, Juhyun Choi, Sung-Suk Suh, Jong Bae Seo

Mol Cells. 2022 Dec 31; 45(12): 963–975. Published online 2022 Dec 21. doi: 10.14348/molcells.2022.0123

PMCID:: PMC9794554

Abstract Article PDF–1.4M

Select item 96038609.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 948193310.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 934144711.

Screening of ferroptosis-related genes in sepsis-induced liver failure and analysis of immune correlation

Qingli Chen, Luxiang Liu, Shuangling Ni

PeerJ. 2022; 10: e13757. Published online 2022 Jul 29. doi: 10.7717/peerj.13757

PMCID:: PMC9341447

Abstract Article PDF–4.2M

Select item 932773712.

Placental structure, function, and mitochondrial phenotype relate to fetal size in each fetal sex in mice

Esteban Salazar-Petres, Daniela Pereira-Carvalho, Jorge Lopez-Tello, Amanda Nancy Sferruzzi-Perri

Biol Reprod. 2022 Jun; 106(6): 1292–1311. Published online 2022 Mar 16. doi: 10.1093/biolre/ioac056

PMCID:: PMC9327737

Abstract Article PDF–3.0M

Select item 877208613.

SLC3A2 inhibits ferroptosis in laryngeal carcinoma via mTOR pathway

Fangxing Wu, Gaoyun Xiong, Zejun Chen, Chenyang Lei, Qianqian Liu, Yundan Bai

Hereditas. 2022; 159: 6. Published online 2022 Jan 20. doi: 10.1186/s41065-022-00225-0

PMCID:: PMC8772086

Abstract Article PDF–5.2M

Select item 863296514.

CD98-induced CD147 signaling stabilizes the Foxp3 protein to maintain tissue homeostasis

JieJie Geng, Ruo Chen, Feng-fan Yang, Peng Lin, Yu-meng Zhu, Xianghui Fu, Ke Wang, Zhuan Feng, Jiao Wu, Hai Zhang, Qi-jing Li, Zhi-Nan Chen, Ping Zhu

Cell Mol Immunol. 2021 Dec; 18(12): 2618–2631. Published online 2021 Nov 10. doi: 10.1038/s41423-021-00785-7

PMCID:: PMC8632965

Abstract Article PDF–6.4M

Select item 862978515.

Identification by proximity labeling of novel lipidic and proteinaceous potential partners of the dopamine transporter

Dolores Piniella, Elena Martínez-Blanco, David Bartolomé-Martín, Ana B. Sanz-Martos, Francisco Zafra

Cell Mol Life Sci. 2021 Dec; 78(23): 7733–7756. Published online 2021 Oct 28. doi: 10.1007/s00018-021-03998-1

PMCID:: PMC8629785

Abstract Article PDF–10M

Select item 807939016.

Metabolic adaptations to hypoxia in the neonatal mouse forebrain can occur independently of the transporters SLC7A5 and SLC3A2

Eamon Fitzgerald, Jennie Roberts, Daniel A. Tennant, James P. Boardman, Amanda J. Drake

Sci Rep. 2021; 11: 9092. Published online 2021 Apr 27. doi: 10.1038/s41598-021-88757-9

PMCID:: PMC8079390

Abstract Article PDF–2.2M

Select item 793877017.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 790021918.

Activation of amino acid metabolic program in cardiac HIF1-alpha-deficient mice

Ivan Menendez-Montes, Beatriz Escobar, Manuel J. Gomez, Teresa Albendea-Gomez, Beatriz Palacios, Elena Bonzon-Kulichenko, Jose Luis Izquierdo-Garcia, Ana Vanessa Alonso, Alessia Ferrarini, Luis Jesus Jimenez-Borreguero, Jesus Ruiz-Cabello, Jesus Vázquez, Silvia Martin-Puig

iScience. 2021 Feb 19; 24(2): 102124. Published online 2021 Feb 3. doi: 10.1016/j.isci.2021.102124

PMCID:: PMC7900219

Abstract Article PDF–6.0M

Select item 741599119.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 708076120.

Loss of the branched-chain amino acid transporter CD98hc alters the development of colonic macrophages in mice

Philipp Wuggenig, Berna Kaya, Hassan Melhem, C. Korcan Ayata, Swiss IBD Cohort Investigators, Petr Hruz, A. Emre Sayan, Hideki Tsumura, Morihiro Ito, Julien Roux, Jan Hendrik Niess

Commun Biol. 2020; 3: 130. Published online 2020 Mar 18. doi: 10.1038/s42003-020-0842-3

PMCID:: PMC7080761

Abstract Article PDF–26M

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