PMC Links for GEO Profiles (Select 8478519) - PMC

Select item 102532011.

CRISPR/Cas9 Knock-Out in Primary Neonatal and Adult Cardiomyocytes Reveals Distinct cAMP Dynamics Regulation by Various PDE2A and PDE3A Isoforms

Egor B. Skryabin, Kirstie A. De Jong, Hariharan Subramanian, Nadja I. Bork, Alexander Froese, Boris V. Skryabin, Viacheslav O. Nikolaev

Cells. 2023 Jun; 12(11): 1543. Published online 2023 Jun 4. doi: 10.3390/cells12111543

PMCID:: PMC10253201

Abstract Article PDF–2.1M

Select item 75788332.

Phosphodiesterase 2A2 regulates mitochondria clearance through Parkin-dependent mitophagy

Miguel J. Lobo, Laia Reverte-Salisa, Ying-Chi Chao, Andreas Koschinski, Frank Gesellchen, Gunasekaran Subramaniam, He Jiang, Samuel Pace, Natasha Larcom, Ester Paolocci, Alexander Pfeifer, Sara Zanivan, Manuela Zaccolo

Commun Biol. 2020; 3: 596. Published online 2020 Oct 21. doi: 10.1038/s42003-020-01311-7

PMCID:: PMC7578833

Abstract Article PDF–4.3M

Select item 63742103.

Structural Analysis of Hippocampal Kinase Signal Transduction

Daniel B. McClatchy, Nam-Kyung Yu, Salvador Martínez-Bartolomé, Reesha Patel, Alexander R. Pelletier, Mathieu Lavalle-Adam, Susan B. Powell, Marissa Roberto, John R. Yates

ACS Chem Neurosci. Author manuscript; available in PMC 2019 Apr 17.

Published in final edited form as: ACS Chem Neurosci. 2018 Dec 19; 9(12): 3072–3085. Published online 2018 Aug 13. doi: 10.1021/acschemneuro.8b00284

PMCID:: PMC6374210

Abstract Article PDF–1.4M

Select item 54237674.

PDE2A2 regulates mitochondria morphology and apoptotic cell death via local modulation of cAMP/PKA signalling

Stefania Monterisi, Miguel J Lobo, Craig Livie, John C Castle, Michael Weinberger, George Baillie, Nicoletta C Surdo, Nshunge Musheshe, Alessandra Stangherlin, Eyal Gottlieb, Rory Maizels, Mario Bortolozzi, Massimo Micaroni, Manuela Zaccolo

eLife. 2017; 6: e21374. Published online 2017 May 2. doi: 10.7554/eLife.21374

PMCID:: PMC5423767

Abstract Article PDF–4.1M

Select item 49353615.

PDE2 activity differs in right and left rat ventricular myocardium and differentially regulates β₂ adrenoceptor-mediated effects

Fernando Soler, Francisco Fernández-Belda, Joaquín Pérez-Schindler, Christoph Handschin, Teodomiro Fuente, Jesús Hernandez-Cascales

Exp Biol Med (Maywood) 2015 Sep; 240(9): 1205–1213. doi: 10.1177/1535370214560969

PMCID:: PMC4935361

Abstract Article PDF–380K

Select item 46175406.

Global genetic analysis in mice unveils central role for cilia in congenital heart disease

You Li, Nikolai T. Klena, George C Gabriel, Xiaoqin Liu, Andrew J. Kim, Kristi Lemke, Yu Chen, Bishwanath Chatterjee, William Devine, Rama Rao Damerla, Chien-fu Chang, Hisato Yagi, Jovenal T. San Agustin, Mohamed Thahir, Shane Anderton, Caroline Lawhead, Anita Vescovi, Herbert Pratt, Judy Morgan, Leslie Haynes, Cynthia L. Smith, Janan T. Eppig, Laura Reinholdt, Richard Francis, Linda Leatherbury, Madhavi K. Ganapathiraju, Kimimasa Tobita, Gregory J. Pazour, Cecilia W. Lo

Nature. Author manuscript; available in PMC 2015 Nov 28.

Published in final edited form as: Nature. 2015 May 28; 521(7553): 520–524. Published online 2015 Mar 25. doi: 10.1038/nature14269

PMCID:: PMC4617540

Abstract Article PDF–518K

Select item 44878317.

Efficacy of B-Type Natriuretic Peptide Is Coupled to Phosphodiesterase 2A in Cardiac Sympathetic Neurons

Dan Li, Chieh-Ju Lu, Guoliang Hao, Hannah Wright, Lavinia Woodward, Kun Liu, Elisa Vergari, Nicoletta C. Surdo, Neil Herring, Manuela Zaccolo, David J. Paterson

Hypertension. Author manuscript; available in PMC 2015 Jul 1.

Published in final edited form as: Hypertension. 2015 Jul; 66(1): 190–198. Published online 2015 Apr 27. doi: 10.1161/HYPERTENSIONAHA.114.05054

PMCID:: PMC4487831

Abstract Article PDF–1.6M

Select item 44099818.

The Distribution of Phosphodiesterase 2a in the Rat Brain

D. T. Stephenson, T. M. Coskran, M. P. Kelly, R. J. Kleiman, D. Morton, S. M. O'neill, C. J. Schmidt, R. J. Weinberg, F. S. Menniti

Neuroscience. Author manuscript; available in PMC 2015 Apr 26.

Published in final edited form as: Neuroscience. 2012 Dec 13; 226: 145–155. Published online 2012 Sep 19. doi: 10.1016/j.neuroscience.2012.09.011

PMCID:: PMC4409981

Abstract Article PDF–1.2M

Select item 31780599.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 316240210.

A Phosphodiesterase 2A Isoform Localized to Mitochondria Regulates Respiration

Rebeca Acin-Perez, Michael Russwurm, Kathrin Günnewig, Melanie Gertz, Georg Zoidl, Lavoisier Ramos, Jochen Buck, Lonny R. Levin, Joachim Rassow, Giovanni Manfredi, Clemens Steegborn

J Biol Chem. 2011 Sep 2; 286(35): 30423–30432. Published online 2011 Jul 1. doi: 10.1074/jbc.M111.266379

PMCID:: PMC3162402

Abstract Article PDF–2.4M

Select item 315462811.

Knockdown of lung phosphodiesterase 2A attenuates alveolar inflammation and protein leak in a two-hit mouse model of acute lung injury

Otgonchimeg Rentsendorj, Mahendra Damarla, Neil R. Aggarwal, Ji-Young Choi, Laura Johnston, Franco R. D'Alessio, Michael T. Crow, David B. Pearse

Am J Physiol Lung Cell Mol Physiol. 2011 Aug; 301(2): L161–L170. Published online 2011 May 13. doi: 10.1152/ajplung.00073.2011

PMCID:: PMC3154628

Abstract Article

Select item 285342012.

Intrinsic sex-specific differences in microvascular endothelial cell phosphodiesterases

Jianjie Wang, Susan Bingaman, Virginia H. Huxley

Am J Physiol Heart Circ Physiol. 2010 Apr; 298(4): H1146–H1154. Published online 2010 Feb 5. doi: 10.1152/ajpheart.00252.2009

PMCID:: PMC2853420

Abstract Article

Select item 277532913.

Mechanism for the allosteric regulation of phosphodiesterase 2A deduced from the X-ray structure of a near full-length construct

Jayvardhan Pandit, Michael D. Forman, Kimberly F. Fennell, Keith S. Dillman, Frank S. Menniti

Proc Natl Acad Sci U S A. 2009 Oct 27; 106(43): 18225–18230. Published online 2009 Oct 14. doi: 10.1073/pnas.0907635106

PMCID:: PMC2775329

Abstract Article PDF–1.7M

Select item 275798014.

Dual Acylation of PDE2A Splice Variant 3: TARGETING TO SYNAPTIC MEMBRANES

Corina Russwurm, Georg Zoidl, Doris Koesling, Michael Russwurm

J Biol Chem. 2009 Sep 18; 284(38): 25782–25790. Published online 2009 Jul 24. doi: 10.1074/jbc.M109.017194

PMCID:: PMC2757980

Abstract Article PDF–1.3M

Select item 274672715.

Immunohistochemical Localization of Phosphodiesterase 2A in Multiple Mammalian Species

Diane T. Stephenson, Tim M. Coskran, Margaret B. Wilhelms, Wendy O. Adamowicz, Michele M. O'Donnell, Kathleen B. Muravnick, Frank S. Menniti, Robin J. Kleiman, Daniel Morton

J Histochem Cytochem. 2009 Oct; 57(10): 933–949. doi: 10.1369/jhc.2009.953471

PMCID:: PMC2746727

Abstract Article PDF–4.3M

Select item 268534416.

Iloprost- and isoproterenol-induced increases in cAMP are regulated by different phosphodiesterases in erythrocytes of both rabbits and humans

Shaquria P. Adderley, Eileen A. Dufaux, Meera Sridharan, Elizabeth A. Bowles, Madelyn S. Hanson, Alan H. Stephenson, Mary L. Ellsworth, Randy S. Sprague

Am J Physiol Heart Circ Physiol. 2009 May; 296(5): H1617–H1624. Published online 2009 Feb 27. doi: 10.1152/ajpheart.01226.2008