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Items: 1 to 20 of 29

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
3.
Deletion of Specific Sphingolipids in Distinct Neurons Improves Spatial Memory in a Mouse Model of Alzheimer’s Disease
Silke Herzer, Cassidy Hagan, Johanna von Gerichten, Vanessa Dieterle, Bogdan Munteanu, Roger Sandhoff, Carsten Hopf, Viola Nordström
Front Mol Neurosci. 2018; 11: 206. Published online 2018 Jun 20. doi: 10.3389/fnmol.2018.00206
PMCID:
PMC6019486
AbstractArticlePDF–4.5M
4.
Inhibition of hepatocellular carcinoma growth by blockade of glycosphingolipid synthesis
Richard Jennemann, Giuseppina Federico, Daniel Mathow, Mariona Rabionet, Francesca Rampoldi, Zoran V. Popovic, Martina Volz, Thomas Hielscher, Roger Sandhoff, Hermann-Josef Gröne
Oncotarget. 2017 Dec 12; 8(65): 109201–109216. Published online 2017 Nov 24. doi: 10.18632/oncotarget.22648
PMCID:
PMC5752514
AbstractArticlePDF–15M
5.
Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development
Shan Li, Amy Teegarden, Emily M. Bauer, Jaewoo Choi, Nadia Messaddeq, David A. Hendrix, Gitali Ganguli-Indra, Mark Leid, Arup K. Indra
Sci Rep. 2017; 7: 13427. Published online 2017 Oct 18. doi: 10.1038/s41598-017-13347-7
PMCID:
PMC5647389
AbstractArticlePDF–5.2M
6.
Diastereomer-specific quantification of bioactive hexosylceramides from bacteria and mammals
Johanna von Gerichten, Kerstin Schlosser, Dominic Lamprecht, Ivan Morace, Matthias Eckhardt, Dagmar Wachten, Richard Jennemann, Hermann-Josef Gröne, Matthias Mack, Roger Sandhoff
J Lipid Res. 2017 Jun; 58(6): 1247–1258. Published online 2017 Apr 3. doi: 10.1194/jlr.D076190
PMCID:
PMC5454501
AbstractArticlePDF–1.4M
7.
Efficacy of Enzyme and Substrate Reduction Therapy with a Novel Antagonist of Glucosylceramide Synthase for Fabry Disease
Karen M Ashe, Eva Budman, Dinesh S Bangari, Craig S Siegel, Jennifer B Nietupski, Bing Wang, Robert J Desnick, Ronald K Scheule, John P Leonard, Seng H Cheng, John Marshall
Mol Med. 2015; 21(1): 389–399. Prepublished online 2015 Apr 30. Published online 2015 Apr 30. doi: 10.2119/molmed.2015.00088
PMCID:
PMC4559530
AbstractArticlePDF–1.6M
8.
Direct acute tubular damage contributes to Shigatoxin-mediated kidney failure
Stefan Porubsky, Giuseppina Federico, Johannes Müthing, Richard Jennemann, Norbert Gretz, Stefan Büttner, Nicholas Obermüller, Oliver Jung, Ingeborg A Hauser, Elisabeth Gröne, Helmut Geiger, Hermann-Josef Gröne, Christoph Betz
J Pathol. 2014 Sep; 234(1): 120–133. Published online 2014 Jul 25. doi: 10.1002/path.4388
PMCID:
PMC4282478
AbstractArticlePDF–4.2M
9.
Ceramides and Glucosylceramides Are Independent Antagonists of Insulin Signaling
Jose A. Chavez, M. Mobin Siddique, Siew Tein Wang, Jianhong Ching, James A. Shayman, Scott A. Summers
J Biol Chem. 2014 Jan 10; 289(2): 723–734. Published online 2013 Nov 8. doi: 10.1074/jbc.M113.522847
PMCID:
PMC3887200
AbstractArticlePDF–1.6M
10.
Sulfatides are required for renal adaptation to chronic metabolic acidosis
Paula Stettner, Soline Bourgeois, Christian Marsching, Milena Traykova-Brauch, Stefan Porubsky, Viola Nordström, Carsten Hopf, Robert Koesters, Roger Sandhoff, Herbert Wiegandt, Carsten A. Wagner, Hermann-Josef Gröne, Richard Jennemann
Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24): 9998–10003. Published online 2013 May 28. doi: 10.1073/pnas.1217775110
Correction in:
Proc Natl Acad Sci U S A. 2013 Sep 3; 110(36): 14813.
PMCID:
PMC3683795
AbstractArticlePDF–675K
11.
Use of a Glycolipid Inhibitor to Ameliorate Renal Cancer in a Mouse Model
Subroto Chatterjee, Nezar Alsaeedi, Jennifer Hou, Veera Venkata Ratnam Bandaru, Lan Wu, Marc K. Halushka, Roberto Pili, Georges Ndikuyeze, Norman J. Haughey
PLoS One. 2013; 8(5): e63726. Published online 2013 May 9. doi: 10.1371/journal.pone.0063726
PMCID:
PMC3650082
AbstractArticlePDF–1.3M
12.
Neuronal Expression of Glucosylceramide Synthase in Central Nervous System Regulates Body Weight and Energy Homeostasis
Viola Nordström, Monja Willershäuser, Silke Herzer, Jan Rozman, Oliver von Bohlen und Halbach, Sascha Meldner, Ulrike Rothermel, Sylvia Kaden, Fabian C. Roth, Clemens Waldeck, Norbert Gretz, Martin Hrabě de Angelis, Andreas Draguhn, Martin Klingenspor, Hermann-Josef Gröne, Richard Jennemann
PLoS Biol. 2013 Mar; 11(3): e1001506. Published online 2013 Mar 12. doi: 10.1371/journal.pbio.1001506
PMCID:
PMC3595213
AbstractArticlePDF–1.7M
13.
Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development
Zhixing Wang, Jay S. Kirkwood, Alan W. Taylor, Jan F. Stevens, Mark Leid, Gitali Ganguli-Indra, Arup K. Indra
J Invest Dermatol. Author manuscript; available in PMC 2013 Sep 1.
Published in final edited form as: J Invest Dermatol. 2013 Mar; 133(3): 668–676. Published online 2012 Oct 25. doi: 10.1038/jid.2012.358
PMCID:
PMC3556343
AbstractArticlePDF–608K
14.
Glycosphingolipids Are Essential for Intestinal Endocytic Function
Richard Jennemann, Sylvia Kaden, Roger Sandhoff, Viola Nordström, Shijun Wang, Martina Volz, Sylvie Robine, Nicole Amen, Ulrike Rothermel, Herbert Wiegandt, Hermann-Josef Gröne
J Biol Chem. 2012 Sep 21; 287(39): 32598–32616. Published online 2012 Jul 31. doi: 10.1074/jbc.M112.371005
PMCID:
PMC3463339
AbstractArticlePDF–12M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
Diverse Endogenous Antigens for Mouse Natural Killer T Cells: Self-Antigens That Are Not Glycosphingolipids
Bo Pei, Anneliese O Speak, Dawn Shepherd, Terry Butters, Vincenzo Cerundolo, Frances M Platt, Mitchell Kronenberg
J Immunol. Author manuscript; available in PMC 2012 Feb 1.
Published in final edited form as: J Immunol. 2011 Feb 1; 186(3): 1348–1360. Published online 2010 Dec 29. doi: 10.4049/jimmunol.1001008
PMCID:
PMC3166644
AbstractArticlePDF–857K
17.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
18.
ABSENCE OF OLIGODENDROGLIAL GLUCOSYLCERAMIDE SYNTHESIS DOES NOT RESULT IN CNS MYELIN ABNORMALITIES OR ALTER THE DYSMYELINATING PHENOTYPE OF CGT-DEFICIENT MICE
Laleh Saadat, Jeffrey L. Dupree, John Kilkus, Xianlin Han, Maria Traka, Richard L. Proia, Glyn Dawson, Brian Popko
Glia. Author manuscript; available in PMC 2011 Mar 1.
Published in final edited form as: Glia. 2010 Mar; 58(4): 391–398. doi: 10.1002/glia.20930
PMCID:
PMC2807477
AbstractArticlePDF–541K
19.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
20.
Cell-specific deletion of glucosylceramide synthase in brain leads to severe neural defects after birth
Richard Jennemann, Roger Sandhoff, Shijun Wang, Eva Kiss, Norbert Gretz, Cecilia Zuliani, Ana Martin-Villalba, Richard Jäger, Hubert Schorle, Marc Kenzelmann, Mahnaz Bonrouhi, Herbert Wiegandt, Hermann-Josef Gröne
Proc Natl Acad Sci U S A. 2005 Aug 30; 102(35): 12459–12464. Published online 2005 Aug 18. doi: 10.1073/pnas.0500893102
PMCID:
PMC1194904
AbstractArticlePDF–553K

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