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Select item 108855181.

Identifying functional dysregulation of NOD2 variant Q902K in patients with Yao syndrome

Jingyuan Zhang, Yi Luo, Bingxuan Wu, Xin Huang, Mengzhu Zhao, Na Wu, Junke Miao, Ji Li, Lei Zhu, Di Wu, Min Shen

Arthritis Res Ther. 2024; 26: 58. Published online 2024 Feb 23. doi: 10.1186/s13075-024-03286-w

PMCID:: PMC10885518

Abstract Article PDF–5.7M

Select item 108594682.

The expanding clinical spectrum of autoinflammatory diseases with NOD2 variants: a case series and literature review

Anastasios Karamanakos, Olga Vougiouka, Evdoxia Sapountzi, Aliki I. Venetsanopoulou, Maria G. Tektonidou, Anastasios E. Germenis, Petros P. Sfikakis, Katerina Laskari

Front Immunol. 2024; 15: 1342668. Published online 2024 Jan 29. doi: 10.3389/fimmu.2024.1342668

PMCID:: PMC10859468

Abstract Article PDF–1.5M

Select item 104337293.

The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling

Mena Abdel-Nour, Leticia A. M. Carneiro, Jeffrey Downey, Jessica Tsalikis, Ahmed Outlioua, Dave Prescott, Leandro Silva Da Costa, Elise S. Hovingh, Armin Farahvash, Ryan G. Gaudet, Raphael Molinaro, Rob van Dalen, Charles C. Y. Lau, Farshad C. Azimi, Nichole K. Escalante, Aaron Trotman-Grant, Jeffrey E. Lee, Scott D. Gray-Owen, Maziar Divangahi, Jane-Jane Chen, Dana J. Philpott, Damien Arnoult, Stephen E. Girardin

Science. Author manuscript; available in PMC 2023 Aug 17.

Published in final edited form as: Science. 2019 Jul 5; 365(6448): eaaw4144. doi: 10.1126/science.aaw4144

PMCID:: PMC10433729

Abstract Article PDF–2.2M

Select item 102907554.

Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries

Zhanju Liu, Ruize Liu, Han Gao, Seulgi Jung, Xiang Gao, Ruicong Sun, Xiaoming Liu, Yongjae Kim, Ho-Su Lee, Yosuke Kawai, Masao Nagasaki, Junji Umeno, Katsushi Tokunaga, Yoshitaka Kinouchi, Atsushi Masamune, Wenzhao Shi, Chengguo Shen, Zhenglin Guo, Kai Yuan, Finn Gen, International Inflammatory Bowel Disease Genetics Consortium, Chinese Inflammatory Bowel Disease Genetics Consortium, Shu Zhu, Dalin Li, Jianjun Liu, Tian Ge, Judy Cho, Mark J. Daly, Dermot P. B. McGovern, Byong Duk Ye, Kyuyoung Song, Yoichi Kakuta, Mingsong Li, Hailiang Huang

Nat Genet. Author manuscript; available in PMC 2023 Nov 8.

Published in final edited form as: Nat Genet. 2023 May; 55(5): 796–806. Published online 2023 May 8. doi: 10.1038/s41588-023-01384-0

PMCID:: PMC10290755

Abstract Article PDF–1.9M

Select item 102682745.

FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA

Yusuke Kasuga, Ryota Ouda, Masashi Watanabe, Xin Sun, Miki Kimura, Shigetsugu Hatakeyama, Koichi S. Kobayashi

Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2218955120. Published online 2023 Jun 6. doi: 10.1073/pnas.2218955120

PMCID:: PMC10268274

Abstract Article PDF–2.3M

Select item 102582856.

Genetic Polymorphisms of NOD2 and ATG16L1 in Different Types of Digestive Tract Inflammation

Mushtaq Hashim Al-Bderee N, Faaz Nassir Al-Saad N, Jawad Al-Imari M, Mudhaher Habbeb S, Mizal Azoz A

Arch Razi Inst. 2023 Feb; 78(1): 493–498. Published online 2023 Feb 28. doi: 10.22092/ARI.2022.359754.2473

PMCID:: PMC10258285

Abstract Article PDF–381K

Select item 100792337.

Allele-dependent interaction of LRRK2 and NOD2 in leprosy

Monica Dallmann-Sauer, Yong Zhong Xu, Ana Lúcia França da Costa, Shao Tao, Tiago Araujo Gomes, Rhana Berto da Silva Prata, Wilian Correa-Macedo, Jérémy Manry, Alexandre Alcaïs, Laurent Abel, Aurélie Cobat, Vinicius M. Fava, Roberta Olmo Pinheiro, Flavio Alves Lara, Christian M. Probst, Marcelo T. Mira, Erwin Schurr

PLoS Pathog. 2023 Mar; 19(3): e1011260. Published online 2023 Mar 27. doi: 10.1371/journal.ppat.1011260

PMCID:: PMC10079233

Abstract Article PDF–2.4M

Select item 99878208.

Association of the rs2111234, rs3135499, rs8057341 polymorphisms in the NOD2 gene with leprosy: A case-control study in the Norte de Santander, Colombia population

Mónica Alexandra Bustos, Luz Dary Castañeda-Castañeda, Carmen Rosa Acosta, Diana García, Diana Patricia Bohada, Raúl Rodríguez, Martha Inírida Guerrero

PLoS One. 2023; 18(3): e0281553. Published online 2023 Mar 6. doi: 10.1371/journal.pone.0281553

PMCID:: PMC9987820

Abstract Article PDF–682K

Select item 99343619.

Variants of NOD2 in Leishmania guyanensis-infected patients with cutaneous leishmaniasis and correlations with plasma circulating pro-inflammatory cytokines

Tirza Gabrielle Ramos de Mesquita, José do Espírito Santo Junior, Josué Lacerda de Souza, Lener Santos da Silva, Tuanny Arruda do Nascimento, Mara Lúcia Gomes de Souza, Marcus Vinitius de Farias Guerra, Rajendranath Ramasawmy

PLoS One. 2023; 18(2): e0281814. Published online 2023 Feb 16. doi: 10.1371/journal.pone.0281814

PMCID:: PMC9934361

Abstract Article PDF–781K

Select item 971371810.

Selective autophagy of RIPosomes maintains innate immune homeostasis during bacterial infection

Subhash Mehto, Kautilya Kumar Jena, Rina Yadav, Swatismita Priyadarsini, Pallavi Samal, Sivaram Krishna, Kollori Dhar, Ashish Jain, Nishant Ranjan Chauhan, Krushna C Murmu, Ramyasingh Bal, Rinku Sahu, Pundrik Jaiswal, Bhabani Sankar Sahoo, Srinivas Patnaik, Thomas A Kufer, Tor Erik Rusten, Swati Chauhan, Punit Prasad, Santosh Chauhan

EMBO J. 2022 Dec; 41(23): e111289. Published online 2022 Oct 11. doi: 10.15252/embj.2022111289

PMCID:: PMC9713718

Abstract Article PDF–14M

Select item 957717511.

Activation of NOD1 and NOD2 in the development of liver injury and cancer

Naoya Omaru, Tomohiro Watanabe, Ken Kamata, Kosuke Minaga, Masatoshi Kudo

Front Immunol. 2022; 13: 1004439. Published online 2022 Oct 4. doi: 10.3389/fimmu.2022.1004439

PMCID:: PMC9577175

Abstract Article PDF–1.5M

Select item 956944212.

NOD2 Signaling Circuitry during Allergen Sensitization Does Not Worsen Experimental Neutrophilic Asthma but Promotes a Th2/Th17 Profile in Asthma Patients but Not Healthy Subjects

Mélodie Bouté, Saliha Ait Yahia, Ying Fan, Daniel Alvarez-Simon, Han Vorng, Joanne Balsamelli, Julie Nanou, Patricia de Nadai, Cécile Chenivesse, Anne Tsicopoulos

Int J Mol Sci. 2022 Oct; 23(19): 11894. Published online 2022 Oct 6. doi: 10.3390/ijms231911894

PMCID:: PMC9569442

Abstract Article PDF–5.1M

Select item 952066813.

Blau syndrome NOD2 mutations result in loss of NOD2 cross-regulatory function

Liming Mao, Atika Dhar, Guangxun Meng, Ivan Fuss, Kim Montgomery-Recht, Zhiqiong Yang, Qiuyun Xu, Atsushi Kitani, Warren Strober

Front Immunol. 2022; 13: 988862. Published online 2022 Sep 15. doi: 10.3389/fimmu.2022.988862

PMCID:: PMC9520668

Abstract Article PDF–15M

Select item 934612014.

Palmitoylation restricts SQSTM1/p62-mediated autophagic degradation of NOD2 to modulate inflammation

Lingli Zhou, Xing He, Liqiu Wang, Ping Wei, Zhe Cai, Song Zhang, Shouheng Jin, Huasong Zeng, Jun Cui

Cell Death Differ. 2022 Aug; 29(8): 1541–1551. Published online 2022 Jan 22. doi: 10.1038/s41418-022-00942-z

PMCID:: PMC9346120

Abstract Article PDF–4.6M

Select item 926261415.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 916555616.

Deleterious Genetic Variation Across the NOD Signaling Pathway Is Associated With Reduced NFKB Signaling Transcription and Upregulation of Alternative Inflammatory Transcripts in Pediatric Inflammatory Bowel Disease

James J Ashton, Konstantinos Boukas, Imogen S Stafford, Guo Cheng, Rachel Haggarty, Tracy A F Coelho, Akshay Batra, Nadeem A Afzal, Anthony P Williams, Marta E Polak, R Mark Beattie, Sarah Ennis

Inflamm Bowel Dis. 2022 Jun; 28(6): 912–922. Published online 2022 Jan 3. doi: 10.1093/ibd/izab318

PMCID:: PMC9165556

Abstract Article PDF–2.1M

Select item 905934117.

SARS-CoV-2/COVID-19 and its relationship with NOD2 and ubiquitination

Edgardo Guzman Rivera, Asha Patnaik, Joann Salvemini, Sanjeev Jain, Katherine Lee, Daniel Lozeau, Qingping Yao

Clin Immunol. 2022 May; 238: 109027. Published online 2022 May 2. doi: 10.1016/j.clim.2022.109027

PMCID:: PMC9059341

Abstract Article PDF–1.2M

Select item 897551318.

Are Pattern Recognition Receptors Associated with Hepatocellular Carcinoma?

Ramazan Dertli, Mehmet Asil, Murat Bıyık, Ahmet Karakarcayıldız, Muharrem Keskin, Yusuf Kayar, Müşerref Başdemirci, Hüseyin Ataseven

Turk J Gastroenterol. 2021 Jul; 32(7): 593–599. Published online 2021 Jul 1. doi: 10.5152/tjg.2021.20657

PMCID:: PMC8975513

Abstract Article PDF–1006K

Select item 892841619.

NOD1 and NOD2 in inflammatory and infectious diseases

Bruno C. Trindade, Grace Y. Chen

Immunol Rev. Author manuscript; available in PMC 2022 Mar 17.

Published in final edited form as: Immunol Rev. 2020 Sep; 297(1): 139–161. Published online 2020 Jul 17. doi: 10.1111/imr.12902

PMCID:: PMC8928416

Abstract Article PDF–1.8M

Select item 891369120.

Valosin-containing protein-regulated endoplasmic reticulum stress causes NOD2-dependent inflammatory responses

Maryam Ghalandary, Yue Li, Thomas Fröhlich, Thomas Magg, Yanshan Liu, Meino Rohlfs, Sebastian Hollizeck, Raffaele Conca, Tobias Schwerd, Holm H. Uhlig, Philip Bufler, Sibylle Koletzko, Aleixo M. Muise, Scott B. Snapper, Fabian Hauck, Christoph Klein, Daniel Kotlarz

Sci Rep. 2022; 12: 3906. Published online 2022 Mar 10. doi: 10.1038/s41598-022-07804-1

PMCID:: PMC8913691

Abstract Article PDF–1.5M

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