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Select item 114029101.

Collagen IV deficiency causes hypertrophic remodeling and endothelium-dependent hyperpolarization in small vessel disease with intracerebral hemorrhage

Sarah McNeilly, Cameron R. Thomson, Laura Gonzalez-Trueba, Yuan Yan Sin, Alessandra Granata, Graham Hamilton, Michelle Lee, Erin Boland, John D. McClure, Cristina Lumbreras-Perales, Alisha Aman, Apoorva A. Kumar, Marco Cantini, Caglar Gök, Delyth Graham, Yasuko Tomono, Christopher D. Anderson, Yinhui Lu, Colin Smith, Hugh S. Markus, Marc Abramowicz, Catheline Vilain, Rustam Al-Shahi Salman, Manuel Salmeron-Sanchez, Atticus H. Hainsworth, William Fuller, Karl E. Kadler, Neil J. Bulleid, Tom Van Agtmael

eBioMedicine. 2024 Sep; 107: 105315. Published online 2024 Aug 30. doi: 10.1016/j.ebiom.2024.105315

PMCID:: PMC11402910

Abstract Article PDF–2.3M

Select item 112969142.

DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples

Fenglong Jiao, Clinton Yu, Andrew Wheat, Lijun Chen, Tung-Shing Mamie Lih, Hui Zhang, Lan Huang

J Proteome Res. Author manuscript; available in PMC 2024 Aug 3.

Published in final edited form as: J Proteome Res. 2024 Aug 2; 23(8): 3269–3279. Published online 2024 Feb 9. doi: 10.1021/acs.jproteome.3c00832

PMCID:: PMC11296914

Abstract Article PDF–1.7M

Select item 110247743.

An AluYa5 Insertion in the 3′UTR of COL4A1 and Cerebral Small Vessel Disease

Chaker Aloui, Lisa Neumann, Françoise Bergametti, Eric Sartori, Marc Herbreteau, Arnaud Maillard, Thibault Coste, Hélène Morel, Dominique Hervé, Hugues Chabriat, Serge Timsit, Irina Viakhireva, Yves Denoyer, Rémi Allibert, Florence Demurger, Cedric Gollion, Patrick Vermersch, Florence Marchelli, Corinne Blugeon, Sophie Lemoine, Claire Tourtier-Bellosta, Alexis Brouazin, Anne-Louise Leutenegger, Eva Pipiras, Elisabeth Tournier-Lasserve

JAMA Netw Open. 2024 Apr; 7(4): e247034. Published online 2024 Apr 17. doi: 10.1001/jamanetworkopen.2024.7034

PMCID:: PMC11024774

Abstract Article

Select item 109064704.

Collagen IV and Podocyte-Related Gene Variants in Patients with Concurrent IgA Nephropathy and Thin Basement Membrane Nephropathy

Hua Xu, XueWen Yu, Yun Li, ZhongHua Huang, Lu Zhang, QinQin Min, JiaXin Bi, ZhenGuo Li, LingYun Liu, YingYing Liang, ZhouWen Xu, HuiLi Sun, ShuDong Yang, MuMin Shao

Nephron Clin Pract. 2023 May; 147(5): 301–310. Published online 2022 Nov 8. doi: 10.1159/000526971

PMCID:: PMC10906470

Abstract Article

Select item 108515915.

Collagen type IV alpha 1 chain (COL4A1) expression in the developing human lung

Laszlo Markasz, Hamid Mobini-Far, Richard Sindelar

BMC Pulm Med. 2024; 24: 75. Published online 2024 Feb 8. doi: 10.1186/s12890-024-02875-4

PMCID:: PMC10851591

Abstract Article PDF–3.8M

Select item 105658766.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 98231317.

Flotillin-2 regulates epidermal growth factor receptor activation, degradation by Cbl-mediated ubiquitination, and cancer growth

David J. Wisniewski, Mariya S. Liyasova, Soumya Korrapati, Xu Zhang, Shashikala Ratnayake, Qingrong Chen, Samuel F. Gilbert, Alexis Catalano, Donna Voeller, Daoud Meerzaman, Udayan Guha, Natalie Porat-Shliom, Christina M. Annunziata, Stanley Lipkowitz

J Biol Chem. 2023 Jan; 299(1): 102766. Published online 2022 Dec 5. doi: 10.1016/j.jbc.2022.102766

PMCID:: PMC9823131

Abstract Article PDF–2.5M

Select item 97613838.

Lysyl hydroxylase 3–mediated post-translational modifications are required for proper biosynthesis of collagen α1α1α2(IV)

Yoshihiro Ishikawa, Yuki Taga, Thibault Coste, Sara F. Tufa, Douglas R. Keene, Kazunori Mizuno, Elisabeth Tournier-Lasserve, Douglas B. Gould

J Biol Chem. 2022 Dec; 298(12): 102713. Published online 2022 Nov 17. doi: 10.1016/j.jbc.2022.102713

PMCID:: PMC9761383

Abstract Article PDF–2.6M

Select item 92316239.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 916191510.

Collagen type IV alpha 1 (COL4A1) silence hampers the invasion, migration and epithelial–mesenchymal transition (EMT) of gastric cancer cells through blocking Hedgehog signaling pathway

Xijuan Cui, Tao Shan, Lina Qiao

Bioengineered. 2022; 13(4): 8972–8981. Published online 2022 Mar 29. doi: 10.1080/21655979.2022.2053799

PMCID:: PMC9161915

Abstract Article PDF–3.3M

Select item 891845311.

A Novel Mutation in COL4A1 Gene in a Chinese Family with Pontine Autosomal Dominant Microangiopathy and Leukoencephalopathy

Qing Li, Chengfeng Wang, Wei Li, Zaiqiang Zhang, Shanshan Wang, Autongsha Wupuer, Xiao Hu, Kalibinuer Wumaier, Yi Zhu, Hongyan Li, Wengui Yu

Transl Stroke Res. 2022; 13(2): 238–244. Published online 2021 Aug 20. doi: 10.1007/s12975-021-00926-0

PMCID:: PMC8918453

Abstract Article PDF–1.0M

Select item 882249812.

Material-driven fibronectin assembly rescues matrix defects due to mutations in collagen IV in fibroblasts

Elie Ngandu Mpoyi, Marco Cantini, Yuan Yan Sin, Lauren Fleming, Dennis W. Zhou, Mercedes Costell, Yinhui Lu, Karl Kadler, Andrés J. García, Tom Van Agtmael, Manuel Salmeron-Sanchez

Biomaterials. Author manuscript; available in PMC 2022 Feb 8.

Published in final edited form as: Biomaterials. 2020 Sep; 252: 120090. Published online 2020 May 3. doi: 10.1016/j.biomaterials.2020.120090

PMCID:: PMC8822498

Abstract Article PDF–2.4M

Select item 852860113.

Collagen Family Genes Associated with Risk of Recurrence after Radiation Therapy for Vestibular Schwannoma and Pan-Cancer Analysis

Qingyuan Shi, Xiaojun Yan, Jiyun Wang, Xiangbao Zhang

Dis Markers. 2021; 2021: 7897994. Published online 2021 Oct 13. doi: 10.1155/2021/7897994

PMCID:: PMC8528601

Abstract Article PDF–1.5M

Select item 833668714.

Replication of top loci from COL4A1/2 associated with white matter hyperintensity burden in ischemic stroke patients

Jiang Li, Vida Abedi, Regeneron Genetic Center, Ramin Zand, Christoph J. Griessenauer

Stroke. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Stroke. 2020 Dec; 51(12): 3751–3755. Published online 2020 Nov 5. doi: 10.1161/STROKEAHA.120.030260

PMCID:: PMC8336687

Abstract Article PDF–741K

Select item 819174215.

Comprehensive proteomic characterization of stem cell-derived extracellular matrices

Héloïse Ragelle, Alexandra Naba, Benjamin L. Larson, Fangheng Zhou, Miralem Prijic, Charles A. Whittaker, Amanda Del Rosario, Robert Langer, Richard O. Hynes, Daniel G. Anderson

Biomaterials. Author manuscript; available in PMC 2021 Jun 10.

Published in final edited form as: Biomaterials. 2017 Jun; 128: 147–159. Published online 2017 Mar 7. doi: 10.1016/j.biomaterials.2017.03.008

PMCID:: PMC8191742

Abstract Article PDF–1.5M

Select item 816503016.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 811526917.

Whole-exome sequencing of Finnish patients with vascular cognitive impairment

Saana Mönkäre, Liina Kuuluvainen, Celia Kun-Rodrigues, Susana Carmona, Johanna Schleutker, Jose Bras, Minna Pöyhönen, Rita Guerreiro, Liisa Myllykangas

Eur J Hum Genet. 2021 Apr; 29(4): 663–671. Published online 2020 Dec 2. doi: 10.1038/s41431-020-00775-9

PMCID:: PMC8115269

Abstract Article PDF–594K

Select item 807872818.

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics

Alexandra Naba, Oliver M. T. Pearce, Amanda Del Rosario, Duanduan Ma, Huiming Ding, Vinothini Rajeeve, Pedro R. Cutillas, Frances R. Balkwill, Richard O. Hynes

J Proteome Res. Author manuscript; available in PMC 2021 Apr 27.

Published in final edited form as: J Proteome Res. 2017 Aug 4; 16(8): 3083–3091. Published online 2017 Jul 19. doi: 10.1021/acs.jproteome.7b00191

PMCID:: PMC8078728

Abstract Article PDF–2.1M

Select item 783943619.

Intracerebral hemorrhage in a neonate with an intragenic COL4A2 duplication

Saskia Koene, Cacha M. P. C. D. Peeters‐Scholte, Jeroen Knijnenburg, Linda S. de Vries, Phebe N. Adama van Scheltema, Marije E. Meuwissen, Sylke J. Steggerda, Gijs W. E. Santen

Am J Med Genet A. 2021 Feb; 185(2): 571–574. Published online 2020 Nov 28. doi: 10.1002/ajmg.a.61988

PMCID:: PMC7839436

Abstract Article PDF–1.5M

Select item 739807720.

COL4A1 promotes the growth and metastasis of hepatocellular carcinoma cells by activating FAK-Src signaling

Ting Wang, Haojie Jin, Jingying Hu, Xi Li, Haoyu Ruan, Huili Xu, Lin Wei, Weihua Dong, Fei Teng, Jianren Gu, Wenxin Qin, Xiaoying Luo, Yujun Hao

J Exp Clin Cancer Res. 2020; 39: 148. Published online 2020 Aug 3. doi: 10.1186/s13046-020-01650-7

PMCID:: PMC7398077

Abstract Article PDF–6.7M

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