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Select item 114766471.

Nrf2/Keap1/ARE regulation by plant secondary metabolites: a new horizon in brain tumor management

Saikat Dewanjee, Hiranmoy Bhattacharya, Chiranjib Bhattacharyya, Pratik Chakraborty, Joshua Fleishman, Athanasios Alexiou, Marios Papadakis, Saurabh Kumar Jha

Cell Commun Signal. 2024; 22: 497. Published online 2024 Oct 15. doi: 10.1186/s12964-024-01878-2

PMCID:: PMC11476647

Abstract Article PDF–3.3M

Select item 113691742.

Proteome-scale characterisation of motif-based interactome rewiring by disease mutations

Johanna Kliche, Leandro Simonetti, Izabella Krystkowiak, Hanna Kuss, Marcel Diallo, Emma Rask, Jakob Nilsson, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2024 Sep; 20(9): 1025–1048. Published online 2024 Jul 15. doi: 10.1038/s44320-024-00055-4

PMCID:: PMC11369174

Abstract Article PDF–2.7M

Select item 113028753.

NRF2-HIF2α Signaling Attenuates Endothelial Cell Senescence and Maintains Intercellular Junctions in Diabetes

Jian Shen, Yifan Lai, Yaner Lu, Yabin Liu, Jinlong Zhang, Yan Wu, Yunan Pan, Haibo Chen, Qiyue Gao, Qucheng Wei, Yuwen Chen, Jian Ye, Yinuo Lin, Bingchen Liu, Jun Jiang, Jinliang Nan

Int J Biol Sci. 2024; 20(10): 4055–4073. Published online 2024 Jul 22. doi: 10.7150/ijbs.96719

PMCID:: PMC11302875

Abstract Article PDF–11M

Select item 112620004.

Metabolic targeting of NRF2 potentiates the efficacy of the TRAP1 inhibitor G-TPP through reduction of ROS detoxification in colorectal cancer

Hong-Yuan Tsai, Mary P Bronner, Jordon K March, John F Valentine, Noah Freeman Shroyer, Lisa A Lai, Teresa A Brentnall, Sheng Pan, Ru Chen

Cancer Lett. Author manuscript; available in PMC 2024 Jul 22.

Published in final edited form as: Cancer Lett. 2022 Nov 28; 549: 215915. Published online 2022 Sep 13. doi: 10.1016/j.canlet.2022.215915

PMCID:: PMC11262000

Abstract Article PDF–3.7M

Select item 112528155.

NRF2 is a spatiotemporal metabolic hub essential for the polyfunctionality of Th2 cells

Garam Choi, Hye-Yeon Ju, Jahyun Bok, Jungseo Choi, Jae Woo Shin, Hansol Oh, Yeojin Jeon, Jiyeon Kim, Daehong Kim, Heesu Moon, Jeong-Eun Lee, Young-Sam Keum, You-Me Kim, Hye Young Kim, Sung Ho Park, Mi-Ryung Han, Yeonseok Chung

Proc Natl Acad Sci U S A. 2024 Jul 9; 121(28): e2319994121. Published online 2024 Jul 3. doi: 10.1073/pnas.2319994121

PMCID:: PMC11252815

Abstract Article PDF–13M

Select item 112397546.

Correlation of PD‐L1 expression with CD8+ T cells and oxidative stress‐related molecules NRF2 and NQO1 in esophageal squamous cell carcinoma

Xin Zhang, Yanan Yang, Hongying Zhao, Zhongqiu Tian, Qing Cao, Yunlong Li, Yajuan Gu, Qinfei Song, Xiumei Hu, Mulan Jin, Xingran Jiang

J Pathol Clin Res. 2024 Jul; 10(4): e12390. Published online 2024 Jul 11. doi: 10.1002/2056-4538.12390

PMCID:: PMC11239754

Abstract Article PDF–20M

Select item 112099357.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111863658.

CPEB1 Controls NRF2 Proteostasis and Ferroptosis Susceptibility in Pancreatic Cancer

Shuxia Zhang, Jingnan Huang, Zhangzhang Lan, Yanlin Xiao, Youyou Liao, Shiva Basnet, Piying Huang, Yunze Li, Jingyu Yan, Yuling Sheng, Wenwen Zhou, Qi Liu, Haoyuan Tan, Yi Tan, Leyong Yuan, Lisheng Wang, Lingyun Dai, Wenyong Zhang, Changzheng Du

Int J Biol Sci. 2024; 20(8): 3156–3172. Published online 2024 Jun 3. doi: 10.7150/ijbs.95962

PMCID:: PMC11186365

Abstract Article PDF–19M

Select item 111532709.

CK2 activity is crucial for proper glucagon expression

Emmanuel Ampofo, Mandy Pack, Selina Wrublewsky, Anne S. Boewe, Aliya F. Spigelman, Hanna Koch, Patrick E. MacDonald, Matthias W. Laschke, Mathias Montenarh, Claudia Götz

Diabetologia. 2024; 67(7): 1368–1385. Published online 2024 Mar 20. doi: 10.1007/s00125-024-06128-1

PMCID:: PMC11153270

Abstract Article PDF–2.0M

Select item 1114802010.

PPIA dictates NRF2 stability to promote lung cancer progression

Weiqiang Lu, Jiayan Cui, Wanyan Wang, Qian Hu, Yun Xue, Xi Liu, Ting Gong, Yiping Lu, Hui Ma, Xinyu Yang, Bo Feng, Qi Wang, Naixia Zhang, Yechun Xu, Mingyao Liu, Ruth Nussinov, Feixiong Cheng, Hongbin Ji, Jin Huang

Nat Commun. 2024; 15: 4703. Published online 2024 Jun 3. doi: 10.1038/s41467-024-48364-4

PMCID:: PMC11148020

Abstract Article PDF–4.0M

Select item 1114610611.

Specific localization of the catalytic subunits of protein kinase CK2 at the centrosomes

M. Faust, J. Gänther, E. Morgenstern, M. Montenarh, C. Götz

Cell Mol Life Sci. 2002 Dec; 59(12): 2155–2164. doi: 10.1007/s000180200022

PMCID:: PMC11146106

Abstract Article PDF–348K

Select item 1113148712.

KIF5C: A new binding partner for protein kinase CK2 with a preference for the CK2α’ subunit

B. Schäfer, C. Götz, J. Dudek, A. Hessenauer, U. Matti, M. Montenarh

Cell Mol Life Sci. 2009 Jan; 66(2): 339–349. Published online 2008 Nov 18. doi: 10.1007/s00018-008-8478-3

PMCID:: PMC11131487

Abstract Article PDF–2.2M

Select item 1111577913.

Protein Kinase CK2 in Health and Disease: CK2: The kinase controlling the Hsp90 chaperone machinery

Y. Miyata

Cell Mol Life Sci. 2009 Jun; 66(11-12): 1840–1849. Published online 2009 Apr 24. doi: 10.1007/s00018-009-9152-0

PMCID:: PMC11115779

Abstract PDF–1.7M

Select item 1111562714.

Céline René, Estelle Lopez, Mireille Claustres, Magali Taulan, Marie-Catherine Romey-Chatelain

Cell Mol Life Sci. 2010 Jul; 67(13): 2297–2309. Published online 2010 Mar 23. doi: 10.1007/s00018-010-0336-4

PMCID:: PMC11115627

Abstract Article PDF–608K

Select item 1111556415.

Protein kinase CK2 and new binding partners during spermatogenesis

Nadja Mannowetz, Sabine Kartarius, Gunther Wennemuth, Mathias Montenarh

Cell Mol Life Sci. 2010 Nov; 67(22): 3905–3913. Published online 2010 Jun 4. doi: 10.1007/s00018-010-0412-9

PMCID:: PMC11115564

Abstract Article PDF–637K

Select item 1111407916.

A complex signaling network involving protein kinase CK2 is required for hepatitis C virus core protein-mediated modulation of the iron-regulatory hepcidin gene expression

Pelagia Foka, Alexios Dimitriadis, Eleni Kyratzopoulou, Dionysios A. Giannimaras, Stefania Sarno, George Simos, Urania Georgopoulou, Avgi Mamalaki

Cell Mol Life Sci. 2014 Nov; 71(21): 4243–4258. Published online 2014 Apr 10. doi: 10.1007/s00018-014-1621-4

PMCID:: PMC11114079

Abstract Article PDF–842K

Select item 1111348417.

Nrf2 and Nrf1 signaling and ER stress crosstalk: implication for proteasomal degradation and autophagy

Hadi Digaleh, Mahmoud Kiaei, Fariba Khodagholi

Cell Mol Life Sci. 2013 Dec; 70(24): 4681–4694. Published online 2013 Jun 26. doi: 10.1007/s00018-013-1409-y

PMCID:: PMC11113484

Abstract Article PDF–490K

Select item 1110831418.

Hepatitis B virus inhibits insulin receptor signaling and impairs liver regeneration via intracellular retention of the insulin receptor

Sebastian Robert Barthel, Regina Medvedev, Thekla Heinrich, Sarah Manon Büchner, Nadja Kettern, Eberhard Hildt

Cell Mol Life Sci. 2016 Nov; 73(21): 4121–4140. Published online 2016 May 7. doi: 10.1007/s00018-016-2259-1

PMCID:: PMC11108314

Abstract Article PDF–12M

Select item 1108889619.

Nuclear factor erythroid 2-related factor 2 promotes radioresistance by regulating glutamate-cysteine ligase modifier subunit and its unique immunoinvasive pattern

Zhaoyuan Xue, Yiliyaer Nuerrula, Yilidana Sitiwaerdi, Mayinur Eli

Biomol Biomed. 2024 Jun 1; 24(3): 545–559. Published online 2024 Jun 1. doi: 10.17305/bb.2024.10184

PMCID:: PMC11088896

Abstract Article PDF–9.2M

Select item 1105939420.

Ceramide kinase-mediated C1P metabolism attenuates acute liver injury by inhibiting the interaction between KEAP1 and NRF2

Wei Dong, Qing Li, Xing Lu, Jianfeng Lan, Zhidong Qiu, Xuehong Wang, Junnan Wang, Xiaojiao Zheng, Sifan Chen, Chong Zhang, Junfei Jin

Exp Mol Med. 2024 Apr; 56(4): 946–958. Published online 2024 Apr 1. doi: 10.1038/s12276-024-01203-4

PMCID:: PMC11059394

Abstract Article PDF–7.4M

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