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Items: 1 to 20 of 58

1.
LIGHT/TNFSF14 promotes CAR-T cell trafficking and cytotoxicity through reversing immunosuppressive tumor microenvironment
Na Zhang, Xiaohong Liu, Juliang Qin, Yue Sun, Hao Xiong, Boxu Lin, Kexin Liu, Binghe Tan, Chenglin Zhang, Chenshen Huang, Shancheng Ren, Mingyao Liu, Bing Du
Mol Ther. 2023 Sep 6; 31(9): 2575–2590. Published online 2023 Jul 5. doi: 10.1016/j.ymthe.2023.06.015
PMCID:
PMC10491984
AbstractArticlePDF–7.2M
2.
LIGHT (TNFSF14) promotes the differentiation of human bone marrow-derived mesenchymal stem cells into functional hepatocyte-like cells
Sook-Kyoung Heo, Ho-Min Yu, Do Kyoung Kim, Hye Jin Seo, Yerang Shin, Sung Ah Kim, Minhui Kim, Youjin Kim, Yoo Jin Lee, Eui-Kyu Noh, Jae-Cheol Jo
PLoS One. 2023; 18(8): e0289798. Published online 2023 Aug 8. doi: 10.1371/journal.pone.0289798
PMCID:
PMC10411951
AbstractArticlePDF–2.9M
3.
High levels of LIGHT/TNFSF14 in patients with Prader–Willi syndrome
M. F. Faienza, G. Brunetti, D. Fintini, G. Grugni, M. G. Wasniewska, A. Crinò, G. D’Amato, L. Piacente, A. Oranger, M. Dicarlo, S. Colucci, M. Grano
J Endocrinol Invest. 2023; 46(9): 1901–1909. Published online 2023 Mar 14. doi: 10.1007/s40618-023-02050-2
PMCID:
PMC10371899
AbstractArticlePDF–640K
4.
HSF1 phosphorylation establishes an active chromatin state via the TRRAP–TIP60 complex and promotes tumorigenesis
Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I. Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai
Nat Commun. 2022; 13: 4355. Published online 2022 Jul 29. doi: 10.1038/s41467-022-32034-4
PMCID:
PMC9338313
AbstractArticlePDF–2.8M
5.
LIGHT controls distinct homeostatic and inflammatory gene expression profiles in esophageal fibroblasts via differential HVEM and LTβR-mediated mechanisms
Mario C. Manresa, Amanda Wu, Quan M. Nhu, Austin W. T. Chiang, Kevin Okamoto, Haruka Miki, Richard Kurten, Elaine Pham, Loan D. Duong, Nathan E. Lewis, Praveen Akuthota, Michael Croft, Seema S. Aceves
Mucosal Immunol. 2022; 15(2): 327–337. Published online 2021 Dec 13. doi: 10.1038/s41385-021-00472-w
PMCID:
PMC8866113
AbstractArticlePDF–13M
6.
HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160
Weifeng Liu, Ting-Fang Chou, Sarah C. Garrett-Thomson, Goo-Young Seo, Elena Fedorov, Udupi A. Ramagopal, Jeffrey B. Bonanno, Qingyang Wang, Kenneth Kim, Scott J. Garforth, Kiyokazu Kakugawa, Hilde Cheroutre, Mitchell Kronenberg, Steven C. Almo
J Exp Med. 2021 Dec 6; 218(12): e20211112. Published online 2021 Oct 28. doi: 10.1084/jem.20211112
PMCID:
PMC8558838
AbstractArticlePDF–7.0M
7.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
8.
LIGHT (TNFSF14) enhances osteogenesis of human bone marrow-derived mesenchymal stem cells
Sook-Kyoung Heo, Yunsuk Choi, Yoo Kyung Jeong, Lan Jeong Ju, Ho-Min Yu, Do Kyoung Kim, Hye Jin Seo, Yoo Jin Lee, Jaekyung Cheon, SuJin Koh, Young Joo Min, Eui-Kyu Noh, Jae-Cheol Jo
PLoS One. 2021; 16(2): e0247368. Published online 2021 Feb 19. doi: 10.1371/journal.pone.0247368
PMCID:
PMC7895395
AbstractArticlePDF–2.8M
9.
LIGHT/LTβR signaling regulates self-renewal and differentiation of hematopoietic and leukemia stem cells
S. S. Höpner, Ana Raykova, R. Radpour, M. A. Amrein, D. Koller, G. M. Baerlocher, C. Riether, A. F. Ochsenbein
Nat Commun. 2021; 12: 1065. Published online 2021 Feb 16. doi: 10.1038/s41467-021-21317-x
PMCID:
PMC7887212
AbstractArticlePDF–5.2M
10.
Plasma TNFSF13B and TNFSF14 Function as Inflammatory Indicators of Severe Adenovirus Pneumonia in Pediatric Patients
Huifeng Fan, Bingtai Lu, Can Cao, Hui Li, Diyuan Yang, Li Huang, Tao Ding, Minhao Wu, Gen Lu
Front Immunol. 2020; 11: 614781. Published online 2021 Jan 19. doi: 10.3389/fimmu.2020.614781
PMCID:
PMC7851050
AbstractArticlePDF–1.4M
11.
Tumor necrosis factor superfamily 14 is critical for the development of renal fibrosis
You Li, Ming Tang, Bo Han, Shun Wu, Shu-jing Li, Qian-hui He, Feng Xu, Gui-qing Li, Kun Zhang, Xu Cao, Quan-you Zheng, Jian Chen, Di Yang, Gui-lian Xu, Ke-qin Zhang
Aging (Albany NY) 2020 Dec 31; 12(24): 25469–25486. Published online 2020 Nov 24. doi: 10.18632/aging.104151
PMCID:
PMC7803499
AbstractArticlePDF–2.4M
12.
Increased Production of LIGHT by T Cells in Eosinophilic Esophagitis Promotes Differentiation of Esophageal Fibroblasts Toward an Inflammatory Phenotype
Mario C. Manresa, Austin W. T. Chiang, Richard C. Kurten, Ranjan Dohil, Howard Brickner, Lucas Dohil, Rana Herro, Praveen Akuthota, Nathan E. Lewis, Michael Croft, Seema S. Aceves
Gastroenterology. Author manuscript; available in PMC 2021 Nov 1.
Published in final edited form as: Gastroenterology. 2020 Nov; 159(5): 1778–1792.e13. Published online 2020 Jul 23. doi: 10.1053/j.gastro.2020.07.035
PMCID:
PMC7726704
AbstractArticlePDF–2.1M
13.
Redesigning HVEM interface for selective binding to LIGHT, BTLA, and CD160
Rojan Shrestha, Sarah Garrett-Thomson, Weifeng Liu, Steven C. Almo, Andras Fiser
Structure. Author manuscript; available in PMC 2021 Nov 3.
Published in final edited form as: Structure. 2020 Nov 3; 28(11): 1197–1205.e2. Published online 2020 Aug 13. doi: 10.1016/j.str.2020.07.013
PMCID:
PMC7642093
AbstractArticlePDF–1.9M
14.
LIGHT aggravates sepsis‐associated acute kidney injury via TLR4‐MyD88‐NF‐κB pathway
Yu Zhong, Shun Wu, Yan Yang, Gui‐qing Li, Li Meng, Quan‐you Zheng, You Li, Gui‐lian Xu, Ke‐qin Zhang, Kan‐fu Peng
J Cell Mol Med. 2020 Oct; 24(20): 11936–11948. Published online 2020 Sep 3. doi: 10.1111/jcmm.15815
PMCID:
PMC7579683
AbstractArticlePDF–2.7M
15.
Levels of the TNF-Related Cytokine LIGHT Increase in Hospitalized COVID-19 Patients with Cytokine Release Syndrome and ARDS
David S. Perlin, Inbal Zafir-Lavie, Lori Roadcap, Shane Raines, Carl F. Ware, Garry A. Neil
mSphere. 2020 Jul-Aug; 5(4): e00699-20. Published online 2020 Aug 12. doi: 10.1128/mSphere.00699-20
PMCID:
PMC7426176
AbstractArticlePDF–270K
16.
Shedding “LIGHT” on the Link between Bone and Fat in Obese Children and Adolescents
Giacomina Brunetti, Maria Felicia Faienza, Laura Piacente, Giuseppina Storlino, Angela Oranger, Gabriele D’Amato, Gianpaolo De Filippo, Silvia Colucci, Maria Grano
Int J Mol Sci. 2020 Jul; 21(13): 4739. Published online 2020 Jul 3. doi: 10.3390/ijms21134739
PMCID:
PMC7370129
AbstractArticlePDF–1.3M
17.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
18.
Increased LIGHT leading to sFlt-1 elevation underlies the pathogenic link between hydatidiform mole and preeclampsia
Takayuki Iriyama, Guan Wang, Midori Yoshikawa, Nobuko Mimura, Haruka Matsui, Seisuke Sayama, Keiichi Kumasawa, Takeshi Nagamatsu, Kaori Koga, Tomomi Kotani, Kaoru Niimi, Eiko Yamamoto, Rodney E. Kellems, Yang Xia, Yutaka Osuga, Tomoyuki Fujii
Sci Rep. 2019; 9: 10107. Published online 2019 Jul 12. doi: 10.1038/s41598-019-46660-4
PMCID:
PMC6625991
AbstractArticlePDF–1.3M
19.
LIGHT/TNFSF14 as a New Biomarker of Bone Disease in Multiple Myeloma Patients Experiencing Therapeutic Regimens
Giacomina Brunetti, Rita Rizzi, Giuseppina Storlino, Sara Bortolotti, Graziana Colaianni, Lorenzo Sanesi, Luciana Lippo, Maria Felicia Faienza, Anna Mestice, Paola Curci, Giorgina Specchia, Maria Grano, Silvia Colucci
Front Immunol. 2018; 9: 2459. Published online 2018 Oct 23. doi: 10.3389/fimmu.2018.02459
PMCID:
PMC6206078
AbstractArticlePDF–1.9M
20.
LIGHT–HVEM signaling in keratinocytes controls development of dermatitis
Rana Herro, Jr-Wen Shui, Sonja Zahner, Daniel Sidler, Yuko Kawakami, Toshiaki Kawakami, Koji Tamada, Mitchell Kronenberg, Michael Croft
J Exp Med. 2018 Feb 5; 215(2): 415–422. doi: 10.1084/jem.20170536
PMCID:
PMC5789407
AbstractArticlePDF–1.4M

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