PMC Links for GEO Profiles (Select 86633949) - PMC

Links from GEO Profiles

Items: 1 to 20 of 50

<< First< Prev

Page of 3

Select item 111709021.

Identification of RAD17 as a candidate cancer predisposition gene in families with histories of pancreatic and breast cancers

Sofie Joris, Philippe Giron, Catharina Olsen, Sara Seneca, Alexander Gheldof, Shula Staessens, Rajendra Bahadur Shahi, Sylvia De Brakeleer, Erik Teugels, Jacques De Grève, Frederik J. Hes

BMC Cancer. 2024; 24: 723. Published online 2024 Jun 13. doi: 10.1186/s12885-024-12442-z

PMCID:: PMC11170902

Abstract Article PDF–1.4M

Select item 91197362.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 90588363.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Abstract Article PDF–2.9M

Select item 87501864.

mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells

David A. Merle, Francesca Provenzano, Mohamed Ali Jarboui, Ellen Kilger, Simon J. Clark, Michela Deleidi, Angela Armento, Marius Ueffing

Antioxidants (Basel) 2021 Dec; 10(12): 1944. Published online 2021 Dec 3. doi: 10.3390/antiox10121944

PMCID:: PMC8750186

Abstract Article PDF–2.7M

Select item 83641815.

Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry

Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang

Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118

PMCID:: PMC8364181

Abstract Article PDF–3.0M

Select item 83529646.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 83188977.

Nuclear translocation promotes proteasomal degradation of human Rad17 protein through the N-terminal destruction boxes

Yasunori Fukumoto, Masayoshi Ikeuchi, Liang Qu, Tyuji Hoshino, Naoto Yamaguchi, Yuji Nakayama, Yasumitsu Ogra

J Biol Chem. 2021 Aug; 297(2): 100831. Published online 2021 Jun 24. doi: 10.1016/j.jbc.2021.100831

PMCID:: PMC8318897

Abstract Article PDF–4.2M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 70532409.

The noncoding function of NELFA mRNA promotes the development of oesophageal squamous cell carcinoma by regulating the Rad17‐RFC2‐5 complex

Jiancheng Xu, Guangchao Wang, Wei Gong, Shichao Guo, Dan Li, Qimin Zhan

Mol Oncol. 2020 Mar; 14(3): 611–624. Published online 2020 Jan 28. doi: 10.1002/1878-0261.12619

PMCID:: PMC7053240

Abstract Article PDF–2.4M

Select item 689239310.

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets

Kristen Mengwasser, Richard Adeyemi, Yumei Leng, Mei Yuk Choi, Connor Clairmont, Alan D’Andrea, Stephen J. Elledge

Mol Cell. Author manuscript; available in PMC 2019 Dec 4.

Published in final edited form as: Mol Cell. 2019 Mar 7; 73(5): 885–899.e6. Published online 2019 Jan 24. doi: 10.1016/j.molcel.2018.12.008

PMCID:: PMC6892393

Abstract Article PDF–1.7M

Select item 623895011.

The RAD17 promoter sequence contains a potential tail-dependent G-quadruplex that downregulates gene expression upon oxidative modification

Judy Zhu, Aaron M. Fleming, Cynthia J. Burrows

ACS Chem Biol. Author manuscript; available in PMC 2019 Sep 21.

Published in final edited form as: ACS Chem Biol. 2018 Sep 21; 13(9): 2577–2584. Published online 2018 Aug 15. doi: 10.1021/acschembio.8b00522

PMCID:: PMC6238950

Abstract Article PDF–995K

Select item 616668212.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 609984613.

Warsaw breakage syndrome DDX11 helicase acts jointly with RAD17 in the repair of bulky lesions and replication through abasic sites

Takuya Abe, Masato Ooka, Ryotaro Kawasumi, Keiji Miyata, Minoru Takata, Kouji Hirota, Dana Branzei

Proc Natl Acad Sci U S A. 2018 Aug 14; 115(33): 8412–8417. Published online 2018 Jul 30. doi: 10.1073/pnas.1803110115

PMCID:: PMC6099846

Abstract Article PDF–1.4M

Select item 553161114.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 520924515.

A network of conserved synthetic lethal interactions for exploration of precision cancer therapy

Rohith Srivas, John Paul Shen, Chih Cheng Yang, Su Ming Sun, Jianfeng Li, Andrew M. Gross, James Jensen, Katherine Licon, Ana Bojorquez-Gomez, Kristin Klepper, Justin Huang, Daniel Pekin, Jia L. Xu, Huwate Yeerna, Vignesh Sivaganesh, Leonie Kollenstart, Haico van Attikum, Pedro Aza-Blanc, Robert W. Sobol, Trey Ideker

Mol Cell. Author manuscript; available in PMC 2017 Aug 4.

Published in final edited form as: Mol Cell. 2016 Aug 4; 63(3): 514–525. Published online 2016 Jul 21. doi: 10.1016/j.molcel.2016.06.022

PMCID:: PMC5209245

Abstract Article PDF–1.6M

Select item 461721116.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 446738617.

Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expression

Fabio Valenti, Federica Ganci, Giulia Fontemaggi, Andrea Sacconi, Sabrina Strano, Giovanni Blandino, Silvia Di Agostino

Oncotarget. 2015 Mar 20; 6(8): 5547–5566. Published online 2015 Feb 5. doi: 10.18632/oncotarget.2587

PMCID:: PMC4467386

Abstract Article PDF–8.9M

Select item 419411118.

Rad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaks

Qinhong Wang, Michael Goldstein, Peter Alexander, Timothy P Wakeman, Tao Sun, Junjie Feng, Zhenkun Lou, Michael B Kastan, Xiao-Fan Wang

EMBO J. 2014 Apr 16; 33(8): 862–877. Published online 2014 Feb 17. doi: 10.1002/embj.201386064

PMCID:: PMC4194111

Abstract Article PDF–4.5M

Select item 413278019.

Ubiquitin-specific Peptidase 20 Regulates Rad17 Stability, Checkpoint Kinase 1 Phosphorylation and DNA Repair by Homologous Recombination

Ilanchezhian Shanmugam, Mohammad Abbas, Farhan Ayoub, Susan Mirabal, Manal Bsaili, Erin K. Caulder, David M. Weinstock, Alan E. Tomkinson, Robert Hromas, Monte Shaheen

J Biol Chem. 2014 Aug 15; 289(33): 22739–22748. Published online 2014 Jun 12. doi: 10.1074/jbc.M114.550459

PMCID:: PMC4132780

Abstract Article PDF–2.5M

Select item 368995720.

Regulation of Rad17 Protein Turnover Unveils an Impact of Rad17-APC Cascade in Breast Carcinogenesis and Treatment

Zhuan Zhou, Chao Jing, Liyong Zhang, Fujita Takeo, Hyun Kim, Yi Huang, Zhihua Liu, Yong Wan

J Biol Chem. 2013 Jun 21; 288(25): 18134–18145. Published online 2013 May 1. doi: 10.1074/jbc.M113.456962

PMCID:: PMC3689957

Abstract Article PDF–3.7M

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to:

Links from GEO Profiles

Items: 1 to 20 of 50

Display Settings:

Send to:

Supplemental Content

Find related data

Recent activity