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Select item 108842401.

Loss of Neogenin alters branchial arch development and leads to craniofacial skeletal defects

Sabrina Quilez, Emilie Dumontier, Christopher Baim, Joseph Kam, Jean-François Cloutier

Front Cell Dev Biol. 2024; 12: 1256465. Published online 2024 Feb 9. doi: 10.3389/fcell.2024.1256465

PMCID:: PMC10884240

Abstract Article PDF–6.8M

Select item 104400342.

Rhinovirus infection induces secretion of endothelin-1 from airway epithelial cells in both in vitro and in vivo models

Alane Blythe C. Dy, Jason Girkin, Antonella Marrocco, Adam Collison, Chimwemwe Mwase, Michael J. O’Sullivan, Thien-Khoi N. Phung, Joerg Mattes, Cynthia Koziol-White, James E. Gern, Yury A. Bochkov, Nathan W. Bartlett, Jin-Ah Park

Respir Res. 2023; 24: 205. Published online 2023 Aug 19. doi: 10.1186/s12931-023-02510-6

PMCID:: PMC10440034

Abstract Article PDF–1.1M

Select item 103301963.

Loss of CEACAM1 in endothelial cells causes hepatic fibrosis

Harrison T. Muturi, Hilda E. Ghadieh, Raziyeh Abdolahipour, Hannah L. Stankus, Getachew Debas Belew, James K. Liu, Marziyeh Salehi Jahromi, Abraham D. Lee, Bernhard B. Singer, Isabella Angeli-Pahim, Tejasav S. Sehrawat, Harmeet Malhi, Stefaan Verhulst, Leo A. van Grunsven, Ali Zarrinpar, Sergio Duarte, Sonia M. Najjar

Metabolism. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: Metabolism. 2023 Jul; 144: 155562. Published online 2023 Apr 21. doi: 10.1016/j.metabol.2023.155562

PMCID:: PMC10330196

Abstract Article PDF–3.0M

Select item 99279364.

Mandibulofacial dysostosis with alopecia results from ET_AR gain-of-function mutations via allosteric effects on ligand binding

Yukiko Kurihara, Toru Ekimoto, Christopher T. Gordon, Yasunobu Uchijima, Ryo Sugiyama, Taro Kitazawa, Akiyasu Iwase, Risa Kotani, Rieko Asai, Véronique Pingault, Mitsunori Ikeguchi, Jeanne Amiel, Hiroki Kurihara

J Clin Invest. 2023 Feb 15; 133(4): e151536. Published online 2023 Feb 15. doi: 10.1172/JCI151536

PMCID:: PMC9927936

Abstract Article PDF–2.7M

Select item 90472995.

Functional interaction between endothelin-1 and ZEB1/YAP signaling regulates cellular plasticity and metastasis in high-grade serous ovarian cancer

Rosanna Sestito, Piera Tocci, Celia Roman, Valeriana Di Castro, Anna Bagnato

J Exp Clin Cancer Res. 2022; 41: 157. Published online 2022 Apr 28. doi: 10.1186/s13046-022-02317-1

PMCID:: PMC9047299

Abstract Article PDF–4.1M

Select item 86648296.

Ciliary Hedgehog signaling patterns the digestive system to generate mechanical forces driving elongation

Ying Yang, Pekka Paivinen, Chang Xie, Alexis Leigh Krup, Tomi P. Makela, Keith E. Mostov, Jeremy F. Reiter

Nat Commun. 2021; 12: 7186. Published online 2021 Dec 10. doi: 10.1038/s41467-021-27319-z

PMCID:: PMC8664829

Abstract Article PDF–5.2M

Select item 79215497.

Endothelin-1 mediated vasoconstriction leads to memory impairment and synaptic dysfunction

Latha Diwakar, Ruturaj Gowaikar, Keerthana Chithanathan, Barathan Gnanabharathi, Deepika Singh Tomar, Vijayalakshmi Ravindranath

Sci Rep. 2021; 11: 4868. Published online 2021 Mar 1. doi: 10.1038/s41598-021-84258-x

PMCID:: PMC7921549

Abstract Article PDF–5.0M

Select item 78171438.

GATA6 is a regulator of sinus node development and heart rhythm

Lara Gharibeh, Abir Yamak, Jamieson Whitcomb, Aizhu Lu, Mathieu Joyal, Hiba Komati, Wenbin Liang, Céline Fiset, Mona Nemer

Proc Natl Acad Sci U S A. 2021 Jan 5; 118(1): e2007322118. Published online 2020 Dec 28. doi: 10.1073/pnas.2007322118

PMCID:: PMC7817143

Abstract Article PDF–2.6M

Select item 76719409.

Multi-layered Spatial Transcriptomics Identify Secretory Factors Promoting Human Hematopoietic Stem Cell Development

Edie I. Crosse, Sabrina Gordon-Keylock, Stanislav Rybtsov, Anahi Binagui-Casas, Hannah Felchle, Nneka C. Nnadi, Kristina Kirschner, Tamir Chandra, Sara Tamagno, David J. Webb, Fiona Rossi, Richard A. Anderson, Alexander Medvinsky

Cell Stem Cell. 2020 Nov 5; 27(5): 822–839.e8. doi: 10.1016/j.stem.2020.08.004

PMCID:: PMC7671940

Abstract Article

Select item 760517110.

Knockout of the Circadian Clock Protein PER1 Results in Sex-Dependent Alterations of ET-1 Production in Mice in Response to a High Salt Diet plus Mineralocorticoid Treatment

Lauren G. Douma, G. Ryan Crislip, Kit-Yan Cheng, Dominique Barral, Sarah Masten, Meaghan Holzworth, Emilio Roig, Krystal Glasford, Kevin Beguiristain, Wendy Li, Phillip Bratanatawira, I. Jeanette Lynch, Brian D. Cain, Charles S. Wingo, Michelle L. Gumz

Can J Physiol Pharmacol. Author manuscript; available in PMC 2021 Sep 11.

Published in final edited form as: Can J Physiol Pharmacol. 2020 Sep; 98(9): 579–586. Published online 2020 Sep 11. doi: 10.1139/cjpp-2019-0688

PMCID:: PMC7605171

Abstract Article PDF–928K

Select item 734345411.

Endothelin-1 induces cellular senescence and fibrosis in cultured myoblasts. A potential mechanism of aging-related sarcopenia

Elena Alcalde-Estévez, Ana Asenjo-Bueno, Patricia Sosa, Gemma Olmos, Patricia Plaza, María Ángeles Caballero-Mora, Diego Rodríguez-Puyol, María Piedad Ruíz-Torres, Susana López-Ongil

Aging (Albany NY) 2020 Jun 30; 12(12): 11200–11223. Published online 2020 Jun 22. doi: 10.18632/aging.103450

PMCID:: PMC7343454

Abstract Article PDF–2.5M

Select item 720007212.

Endothelin receptor-A mediates degradation of the glomerular endothelial surface layer via pathologic crosstalk between activated podocytes and glomerular endothelial cells.

Kerstin Ebefors, Robert J. Wiener, Liping Yu, Evren U. Azeloglu, Zhengzi Yi, Fu Jia, Weijia Zhang, Margaret H. Baron, John C. He, Börje Haraldsson, Ilse Daehn

Kidney Int. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Kidney Int. 2019 Oct; 96(4): 957–970. Published online 2019 May 22. doi: 10.1016/j.kint.2019.05.007

PMCID:: PMC7200072

Abstract Article PDF–1.9M

Select item 719536713.

Endothelin-1 signaling maintains glial progenitor proliferation in the postnatal subventricular zone

Katrina L. Adams, Giulia Riparini, Payal Banerjee, Marjolein Breur, Marianna Bugiani, Vittorio Gallo

Nat Commun. 2020; 11: 2138. Published online 2020 May 1. doi: 10.1038/s41467-020-16028-8

PMCID:: PMC7195367

Abstract Article PDF–6.9M

Select item 717635014.

Endothelin-1 Mediates the Systemic and Renal Hemodynamic Effects of GPR81 Activation

Natalie K. Jones, Kevin Stewart, Alicja Czopek, Robert I. Menzies, Adrian Thomson, Carmel M. Moran, Carolynn Cairns, Bryan R. Conway, Laura Denby, Dawn E.W. Livingstone, John Wiseman, Patrick W. Hadoke, David J. Webb, Neeraj Dhaun, James W. Dear, John J. Mullins, Matthew A. Bailey

Hypertension. 2020 May; 75(5): 1213–1222. Published online 2020 Mar 23. doi: 10.1161/HYPERTENSIONAHA.119.14308

PMCID:: PMC7176350

Abstract Article PDF–873K

Select item 700329715.

Loss of Histone H3 K79 Methyltransferase Dot1l Facilitates Kidney Fibrosis by Upregulating Endothelin 1 through Histone Deacetylase 2

Long Zhang, Lihe Chen, Chao Gao, Enuo Chen, Andrea R. Lightle, Llewellyn Foulke, Bihong Zhao, Paul J. Higgins, Wenzheng Zhang

J Am Soc Nephrol. 2020 Feb; 31(2): 337–349. Published online 2019 Dec 16. doi: 10.1681/ASN.2019070739

PMCID:: PMC7003297

Abstract Article

Select item 695148916.

Irreversible and sustained upregulation of endothelin axis during oncogene-associated pancreatic inflammation and cancer

Suprit Gupta, Avi Prajapati, Mansi Gulati, Shailendra K. Gautam, Sushil Kumar, Vipin Dalal, Geoffrey A. Talmon, Satyanarayana Rachagani, Maneesh Jain

Neoplasia. 2020 Feb; 22(2): 98–110. Published online 2020 Jan 7. doi: 10.1016/j.neo.2019.11.001

PMCID:: PMC6951489

Abstract Article PDF–5.9M

Select item 691267917.

The G Protein-Coupled Bile Acid Receptor TGR5 (Gpbar1) Modulates Endothelin-1 Signaling in Liver

Caroline Klindt, Maria Reich, Birte Hellwig, Jan Stindt, Jörg Rahnenführer, Jan G. Hengstler, Karl Köhrer, Kristina Schoonjans, Dieter Häussinger, Verena Keitel

Cells. 2019 Nov; 8(11): 1467. Published online 2019 Nov 19. doi: 10.3390/cells8111467

PMCID:: PMC6912679

Abstract Article PDF–4.8M

Select item 685870318.

Astrocytic endothelin-1 overexpression promotes neural progenitor cells proliferation and differentiation into astrocytes via the Jak2/Stat3 pathway after stroke

Xiao Cheng, Patrick K. K. Yeung, Ke Zhong, Prince L. M. Zilundu, Lihua Zhou, Sookja K. Chung

J Neuroinflammation. 2019; 16: 227. Published online 2019 Nov 16. doi: 10.1186/s12974-019-1597-y

PMCID:: PMC6858703

Abstract Article PDF–4.2M

Select item 683110419.

Endothelin signalling mediates experience-dependent myelination in the CNS

Matthew Swire, Yuri Kotelevtsev, David J Webb, David A Lyons, Charles ffrench-Constant

eLife. 2019; 8: e49493. Published online 2019 Oct 28. doi: 10.7554/eLife.49493

PMCID:: PMC6831104

Abstract Article PDF–7.9M

Select item 662924020.

Tie2 regulates endocardial sprouting and myocardial trabeculation

Xianghu Qu, Cristina Harmelink, H. Scott Baldwin

JCI Insight. 2019 Jul 11; 4(13): e96002. Published online 2019 Jul 11. doi: 10.1172/jci.insight.96002

PMCID:: PMC6629240

Abstract Article PDF–60M

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