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Select item 112370451.

Quantifiable and reproducible phenotypic assessment of a constitutive knockout mouse model for congenital nephrotic syndrome of the Finnish type

Katharina Lemberg, Nils D. Mertens, Kirollos Yousef, Ronen Schneider, Lea M. Merz, Bshara Mansour, Daanya Salmanullah, Caroline M. Kolvenbach, Ken Saida, Seyoung Yu, Selina Hölzel, Andrew Steinsapir, Kevin A. Goncalves, Camille Nicolas Frank, Gijs A. C. Franken, Shirlee Shril, Florian Buerger, Friedhelm Hildebrandt

Sci Rep. 2024; 14: 15916. Published online 2024 Jul 10. doi: 10.1038/s41598-024-64883-y

PMCID:: PMC11237045

Abstract Article PDF–2.3M

Select item 107180802.

Fgf8 promotes survival of nephron progenitors by regulating BAX/BAKmediated apoptosis.

Matthew J. Anderson, Salvia Misaghian, Nirmala Sharma, Alan O. Perantoni, Mark Lewandoski

Differentiation. Author manuscript; available in PMC 2024 Mar 1.

Published in final edited form as: Differentiation. 2023 Mar-Apr; 130: 7–15. Published online 2022 Dec 6. doi: 10.1016/j.diff.2022.12.001

PMCID:: PMC10718080

Abstract Article PDF–1.9M

Select item 101032623.

Tet2- and Tet3-Mediated Cytosine Hydroxymethylation in Six2 Progenitor Cells in Mice Is Critical for Nephron Progenitor Differentiation and Nephron Endowment

Xiujie Liang, Tamas Aranyi, Jianfu Zhou, Yuting Guan, Hailong Hu, Hongbo Liu, Katalin Susztak

J Am Soc Nephrol. 2023 Apr; 34(4): 572–589. Published online 2022 Dec 15. doi: 10.1681/ASN.2022040460

PMCID:: PMC10103262

Abstract Article

Select item 98700894.

ZEB2 controls kidney stromal progenitor differentiation and inhibits abnormal myofibroblast expansion and kidney fibrosis

Sudhir Kumar, Xueping Fan, Hila Milo Rasouly, Richa Sharma, David J. Salant, Weining Lu

JCI Insight. 2023 Jan 10; 8(1): e158418. Published online 2023 Jan 10. doi: 10.1172/jci.insight.158418

PMCID:: PMC9870089

Abstract Article PDF–8.1M

Select item 92329755.

Disruption of mitochondrial complex III in cap mesenchyme but not in ureteric progenitors results in defective nephrogenesis associated with amino acid deficiency

Nan Guan, Hanako Kobayashi, Ken Ishii, Olena Davidoff, Feng Sha, Talat A. Ikizler, Chuan-Ming Hao, Navdeep S. Chandel, Volker H. Haase

Kidney Int. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: Kidney Int. 2022 Jul; 102(1): 108–120. Published online 2022 Mar 24. doi: 10.1016/j.kint.2022.02.030

PMCID:: PMC9232975

Abstract Article PDF–1.7M

Select item 90576086.

Loss of the collagen IV modifier prolyl 3-hydroxylase 2 causes thin basement membrane nephropathy

Hande Aypek, Christoph Krisp, Shun Lu, Shuya Liu, Dominik Kylies, Oliver Kretz, Guochao Wu, Manuela Moritz, Kerstin Amann, Kerstin Benz, Ping Tong, Zheng-mao Hu, Sulaiman M. Alsulaiman, Arif O. Khan, Maik Grohmann, Timo Wagner, Janina Müller-Deile, Hartmut Schlüter, Victor G. Puelles, Carsten Bergmann, Tobias B. Huber, Florian Grahammer

J Clin Invest. 2022 May 2; 132(9): e147253. Published online 2022 May 2. doi: 10.1172/JCI147253

PMCID:: PMC9057608

Abstract Article PDF–17M

Select item 88794637.

Immunohistochemical Expression Pattern of FGFR1, FGFR2, RIP5, and HIP2 in Developing and Postnatal Kidneys of Dab1^−/− (yotari) Mice

Nela Kelam, Anita Racetin, Yu Katsuyama, Katarina Vukojević, Sandra Kostić

Int J Mol Sci. 2022 Feb; 23(4): 2025. Published online 2022 Feb 11. doi: 10.3390/ijms23042025

PMCID:: PMC8879463

Abstract Article PDF–10M

Select item 88075958.

Generation of the organotypic kidney structure by integrating pluripotent stem cell-derived renal stroma

Shunsuke Tanigawa, Etsuko Tanaka, Koichiro Miike, Tomoko Ohmori, Daisuke Inoue, Chen-Leng Cai, Atsuhiro Taguchi, Akio Kobayashi, Ryuichi Nishinakamura

Nat Commun. 2022; 13: 611. Published online 2022 Feb 1. doi: 10.1038/s41467-022-28226-7

Correction in:: Nat Commun. 2023; 14: 1874.

PMCID:: PMC8807595

Abstract Article PDF–5.4M

Select item 84299779.

Phosphorylation of slit diaphragm proteins NEPHRIN and NEPH1 upon binding of HGF promotes podocyte repair

Ashish K. Solanki, Ehtesham Arif, Pankaj Srivastava, Christopher M. Furcht, Bushra Rahman, Pei Wen, Avinash Singh, Lawrence B. Holzman, Wayne R. Fitzgibbon, Milos N. Budisavljevic, Glenn P. Lobo, Sang-Ho Kwon, Zhe Han, Matthew J. Lazzara, Joshua H. Lipschutz, Deepak Nihalani

J Biol Chem. 2021 Sep; 297(3): 101079. Published online 2021 Aug 13. doi: 10.1016/j.jbc.2021.101079

PMCID:: PMC8429977

Abstract Article PDF–4.8M

Select item 801189010.

Endoplasmic reticulum–associated degradation is required for nephrin maturation and kidney glomerular filtration function

Sei Yoshida, Xiaoqiong Wei, Gensheng Zhang, Christopher L. O’Connor, Mauricio Torres, Zhangsen Zhou, Liangguang Lin, Rajasree Menon, Xiaoxi Xu, Wenyue Zheng, Yi Xiong, Edgar Otto, Chih-Hang Anthony Tang, Rui Hua, Rakesh Verma, Hiroyuki Mori, Yang Zhang, Chih-Chi Andrew Hu, Ming Liu, Puneet Garg, Jeffrey B. Hodgin, Shengyi Sun, Markus Bitzer, Ling Qi

J Clin Invest. 2021 Apr 1; 131(7): e143988. Published online 2021 Apr 1. doi: 10.1172/JCI143988

PMCID:: PMC8011890

Abstract Article PDF–22M

Select item 793877011.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 792017612.

SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance

Manuel Rogg, Jasmin I. Maier, Robert Dotzauer, Nadine Artelt, Oliver Kretz, Martin Helmstädter, Ahmed Abed, Alena Sammarco, August Sigle, Dominik Sellung, Patrick Dinse, Karoline Reiche, Mako Yasuda-Yamahara, Martin L. Biniossek, Gerd Walz, Martin Werner, Nicole Endlich, Oliver Schilling, Tobias B. Huber, Christoph Schell

J Am Soc Nephrol. 2021 Mar; 32(3): 563–579. Published online 2021 Jan 29. doi: 10.1681/ASN.2020081126

PMCID:: PMC7920176

Abstract Article

Select item 722876613.

R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors

Valerie PI Vidal, Fariba Jian-Motamedi, Samah Rekima, Elodie P Gregoire, Emmanuelle Szenker-Ravi, Marc Leushacke, Bruno Reversade, Marie-Christine Chaboissier, Andreas Schedl

eLife. 2020; 9: e53895. Published online 2020 May 1. doi: 10.7554/eLife.53895

PMCID:: PMC7228766

Abstract Article PDF–10M

Select item 650301914.

Foxc2 is essential for podocyte function

Daniel Nilsson, Mikael Heglind, Zahra Arani, Sven Enerbäck

Physiol Rep. 2019 May; 7(9): e14083. Published online 2019 May 6. doi: 10.14814/phy2.14083

PMCID:: PMC6503019

Abstract Article PDF–15M

Select item 644239715.

Global polysome analysis of normal and injured podocytes

Masahiro Okabe, Masaru Motojima, Yoichi Miyazaki, Ira Pastan, Takashi Yokoo, Taiji Matsusaka

Am J Physiol Renal Physiol. 2019 Feb 1; 316(2): F241–F252. Published online 2018 Oct 31. doi: 10.1152/ajprenal.00115.2018

PMCID:: PMC6442397

Abstract Article

Select item 636204716.

Reconstitution of the embryonic kidney identifies a donor cell contribution to the renal vasculature upon transplantation

Yoichi Murakami, Hidekazu Naganuma, Shunsuke Tanigawa, Toshihiko Fujimori, Masatoshi Eto, Ryuichi Nishinakamura

Sci Rep. 2019; 9: 1172. Published online 2019 Feb 4. doi: 10.1038/s41598-018-37793-z

PMCID:: PMC6362047

Abstract Article PDF–2.2M

Select item 631760517.

DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation

Nicola Wanner, Julia Vornweg, Alexander Combes, Sean Wilson, Julia Plappert, Gesa Rafflenbeul, Victor G. Puelles, Raza-Ur Rahman, Timur Liwinski, Saskia Lindner, Florian Grahammer, Oliver Kretz, Mary E. Wlodek, Tania Romano, Karen M. Moritz, Melanie Boerries, Hauke Busch, Stefan Bonn, Melissa H. Little, Wibke Bechtel-Walz, Tobias B. Huber

J Am Soc Nephrol. 2019 Jan; 30(1): 63–78. Published online 2018 Dec 5. doi: 10.1681/ASN.2018070736

PMCID:: PMC6317605

Abstract Article

Select item 628838618.

WNT/β-catenin signaling plays a crucial role in myoblast fusion through regulation of nephrin expression during development

Akiko Suzuki, Ryohei Minamide, Junichi Iwata

Development. 2018 Dec 1; 145(23): dev168351. Published online 2018 Nov 27. doi: 10.1242/dev.168351

PMCID:: PMC6288386

Abstract Article

Select item 601021119.

Nephrin is necessary for podocyte recovery following injury in an adult mature glomerulus

Rakesh Verma, Madhusudan Venkatareddy, Anne Kalinowski, Theodore Li, Joanna Kukla, Ashomathi Mollin, Gabriel Cara-Fuentes, Sanjeevkumar R. Patel, Puneet Garg

PLoS One. 2018; 13(6): e0198013. Published online 2018 Jun 20. doi: 10.1371/journal.pone.0198013

PMCID:: PMC6010211

Abstract Article PDF–24M

Select item 581464420.

Glomerular mesangial cell recruitment and function require the co-receptor neuropilin-1

Christina S. Bartlett, Rizaldy P. Scott, Isabel Anna Carota, Monika L. Wnuk, Yashpal S. Kanwar, Jeffrey H. Miner, Susan E. Quaggin

Am J Physiol Renal Physiol. 2017 Dec 1; 313(6): F1232–F1242. Published online 2017 Aug 16. doi: 10.1152/ajprenal.00311.2017

PMCID:: PMC5814644

Abstract Article

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