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Items: 1 to 20 of 195

1.
Interaction between Staphylococcus Agr virulence and neutrophils regulates pathogen expansion and skin inflammation
Masanori Matsumoto, Seitaro Nakagawa, Lingzhi Zhang, Yuumi Nakamura, Amer E. Villaruz, Michael Otto, Christiane Wolz, Naohiro Inohara, Gabriel Núnez
Cell Host Microbe. Author manuscript; available in PMC 2024 Apr 18.
Published in final edited form as: Cell Host Microbe. 2021 Jun 9; 29(6): 930–940.e4. Published online 2021 Apr 13. doi: 10.1016/j.chom.2021.03.007
PMCID:
PMC11024063
AbstractArticlePDF–2.2M
2.
Neutrophils and NADPH Oxidases Are Major Contributors to Mild but Not Severe Ischemic Acute Kidney Injury in Mice
Csaba Révész, Tamás Kaucsár, Mária Godó, Krisztián Bocskai, Tibor Krenács, Attila Mócsai, Gábor Szénási, Péter Hamar
Int J Mol Sci. 2024 Mar; 25(5): 2948. Published online 2024 Mar 3. doi: 10.3390/ijms25052948
PMCID:
PMC10932292
AbstractArticlePDF–8.1M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
Mitochondrial IRG1 traps MCL-1 to induce hepatocyte apoptosis and promote carcinogenesis
Liyuan Zhang, Yue Dong, Luxin Zhang, Minjun Wang, Ye Zhou, Kaiwei Jia, Suyuan Wang, Mu Wang, Yunhui Li, Shudan Luo, Shan Lu, Yiwen Fan, Dingji Zhang, Yingyun Yang, Nan Li, Yizhi Yu, Xuetao Cao, Jin Hou
Cell Death Dis. 2023 Sep; 14(9): 625. Published online 2023 Sep 22. doi: 10.1038/s41419-023-06155-7
PMCID:
PMC10517141
AbstractArticlePDF–5.9M
5.
The RNA binding proteins TIA1 and TIAL1 promote Mcl1 mRNA translation to protect germinal center responses from apoptosis
Ines C. Osma-Garcia, Mailys Mouysset, Dunja Capitan-Sobrino, Yann Aubert, Martin Turner, Manuel D. Diaz-Muñoz
Cell Mol Immunol. 2023 Sep; 20(9): 1063–1076. Published online 2023 Jul 20. doi: 10.1038/s41423-023-01063-4
PMCID:
PMC10469172
AbstractArticlePDF–5.7M
6.
Steroidogenic factor 1 (SF-1; Nr5a1) regulates the formation of the ovarian reserve
Camilla H. K. Hughes, Olivia E. Smith, Marie-Charlotte Meinsohn, Mylène Brunelle, Nicolas Gévry, Bruce D. Murphy
Proc Natl Acad Sci U S A. 2023 Aug 8; 120(32): e2220849120. Published online 2023 Jul 26. doi: 10.1073/pnas.2220849120
PMCID:
PMC10410717
AbstractArticlePDF–3.9M
7.
SARS-CoV-2 N protein enhances the anti-apoptotic activity of MCL-1 to promote viral replication
Pan Pan, Weiwei Ge, Zhiwei Lei, Wei luo, Yuqing Liu, Zhanwen Guan, Lumiao Chen, Zhenyang Yu, Miaomiao Shen, Dingwen Hu, Qi Xiang, Wenbiao Wang, Pin Wan, Mingfu Tian, Yang Yu, Zhen Luo, Xulin Chen, Heng Xiao, Qiwei Zhang, Xujing Liang, Xin Chen, Yongkui Li, Jianguo Wu
Signal Transduct Target Ther. 2023; 8: 194. Published online 2023 May 9. doi: 10.1038/s41392-023-01459-8
PMCID:
PMC10169150
AbstractArticlePDF–6.6M
8.
Myeloid expression of the anti-apoptotic protein Mcl1 is required in anti-myeloperoxidase vasculitis but myeloperoxidase inhibition is not protective
Fernanda Florez-Barros, Siobhan Bearder, Bengt Kull, Adrian Freeman, Attila Mócsai, Michael G. Robson
Kidney Int. 2023 Jan; 103(1): 134–143. doi: 10.1016/j.kint.2022.08.028
PMCID:
PMC10166712
AbstractArticle
9.
Selective inhibition of MCL1 overcomes venetoclax resistance in a murine model of myelodysplastic syndromes
Melissa A. Fischer, Yuanbin Song, Maria P. Arrate, Rana Gbyli, Matthew T. Villaume, Brianna N. Smith, Merrida A. Childress, Thomas P. Stricker, Stephanie Halene, Michael R. Savona
Haematologica. 2023 Feb 1; 108(2): 522–531. Published online 2022 Aug 18. doi: 10.3324/haematol.2022.280631
PMCID:
PMC9890032
AbstractArticlePDF–2.2M
10.
Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death
Farrah El-Saafin, Maria I. Bergamasco, Yunshun Chen, Rose E. May, Prabagaran Esakky, Soroor Hediyeh-zadeh, Mathew Dixon, Stephen Wilcox, Melissa J. Davis, Andreas Strasser, Gordon K. Smyth, Tim Thomas, Anne K. Voss
Cell Death Differ. 2022 May; 29(5): 1013–1027. Published online 2022 Mar 31. doi: 10.1038/s41418-022-00982-5
PMCID:
PMC9091217
AbstractArticlePDF–7.2M
11.
miR-340-5p Mediates Cardiomyocyte Oxidative Stress in Diabetes-Induced Cardiac Dysfunction by Targeting Mcl-1
Yinghong Zhu, Xuewen Yang, Jing Zhou, Long Chen, Pengfei Zuo, Lin Chen, Lan Jiang, Ting Li, Dejiang Wang, Yingyi Xu, Qiushi Li, Yi Yan
Oxid Med Cell Longev. 2022; 2022: 3182931. Published online 2022 Jan 27. doi: 10.1155/2022/3182931
PMCID:
PMC8813269
AbstractArticlePDF–3.8M
12.
Oligodendrocytes depend on MCL-1 to prevent spontaneous apoptosis and white matter degeneration
Abigail H. Cleveland, Alejandra Romero-Morales, Laurent Alfonso Azcona, Melisa Herrero, Viktoriya D. Nikolova, Sheryl Moy, Orna Elroy-Stein, Vivian Gama, Timothy R. Gershon
Cell Death Dis. 2021 Dec; 12(12): 1133. Published online 2021 Dec 6. doi: 10.1038/s41419-021-04422-z
PMCID:
PMC8648801
AbstractArticlePDF–7.7M
13.
Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function
Kirsteen J. Campbell, Susan M. Mason, Matthew L. Winder, Rosalie B. E. Willemsen, Catherine Cloix, Hannah Lawson, Nicholas Rooney, Sandeep Dhayade, Andrew H. Sims, Karen Blyth, Stephen W. G. Tait
Cell Death Differ. 2021 Sep; 28(9): 2589–2600. Published online 2021 Mar 31. doi: 10.1038/s41418-021-00773-4
PMCID:
PMC8408186
AbstractArticlePDF–2.1M
14.
Impaired ribosome biogenesis checkpoint activation induces p53-dependent MCL-1 degradation and MYC-driven lymphoma death
Ana Domostegui, Suresh Peddigari, Carol A. Mercer, Flavia Iannizzotto, Marta L. Rodriguez, Marta Garcia-Cajide, Virginia Amador, Sarah T. Diepstraten, Gemma L. Kelly, Ramón Salazar, Sara C. Kozma, Eric P. Kusnadi, Jian Kang, Antonio Gentilella, Richard B. Pearson, George Thomas, Joffrey Pelletier
Blood. 2021 Jun 17; 137(24): 3351–3364. Prepublished online 2021 Jan 14. doi: 10.1182/blood.2020007452
PMCID:
PMC8212515
AbstractArticle
15.
The Role of Mcl-1 in Embryonic Neural Precursor Cell Apoptosis
Robert T. Flemmer, Sarah P. Connolly, Brittany A. Geizer, Joseph T. Opferman, Jacqueline L. Vanderluit
Front Cell Dev Biol. 2021; 9: 659531. Published online 2021 Apr 20. doi: 10.3389/fcell.2021.659531
PMCID:
PMC8093775
AbstractArticlePDF–1.3M
16.
RORγt limits the amount of the cytokine receptor γc through the prosurvival factor Bcl-xL in developing thymocytes
Davinna L. Ligons, SuJin Hwang, Adam T. Waickman, Joo-Young Park, Megan A. Luckey, Jung-Hyun Park
Sci Signal. Author manuscript; available in PMC 2021 Apr 21.
Published in final edited form as: Sci Signal. 2018 Aug 28; 11(545): eaam8939. Published online 2018 Aug 28. doi: 10.1126/scisignal.aam8939
PMCID:
PMC8058635
AbstractArticlePDF–1.5M
17.
Requirement for antiapoptotic MCL-1 during early erythropoiesis
Meghan E. Turnis, Ewa Kaminska, Kaitlyn H. Smith, Brittany J. Kartchner, Peter Vogel, Jonathan D. Laxton, Richard A. Ashmun, Paul A. Ney, Joseph T. Opferman
Blood. 2021 Apr 8; 137(14): 1945–1958. Prepublished online 2021 Jan 11. doi: 10.1182/blood.2020006916
PMCID:
PMC8033457
AbstractArticle
18.
MCT1 Deletion in Oligodendrocyte Lineage Cells Causes Late-Onset Hypomyelination and Axonal Degeneration
Thomas Philips, Yevgeniya A. Mironova, Yan Jouroukhin, Jeannie Chew, Svetlana Vidensky, Mohamed H. Farah, Mikhail V. Pletnikov, Dwight E. Bergles, Brett M. Morrison, Jeffrey D. Rothstein
Cell Rep. Author manuscript; available in PMC 2021 Apr 5.
Published in final edited form as: Cell Rep. 2021 Jan 12; 34(2): 108610. doi: 10.1016/j.celrep.2020.108610
PMCID:
PMC8020895
AbstractArticlePDF–3.2M
19.
Immunotherapy for breast cancer using EpCAM aptamer tumor-targeted gene knockdown
Ying Zhang, Xuemei Xie, Pourya Naderi Yeganeh, Dian-Jang Lee, David Valle-Garcia, Karla F. Meza-Sosa, Caroline Junqueira, Jiayu Su, Hongbo R. Luo, Winston Hide, Judy Lieberman
Proc Natl Acad Sci U S A. 2021 Mar 2; 118(9): e2022830118. Published online 2021 Feb 24. doi: 10.1073/pnas.2022830118
PMCID:
PMC7936362
AbstractArticlePDF–2.6M
20.
Persistent hepatocyte apoptosis promotes tumorigenesis from diethylnitrosamine-transformed hepatocytes through increased oxidative stress, independent of compensatory liver regeneration
Yasutoshi Nozaki, Hayato Hikita, Satoshi Tanaka, Kenji Fukumoto, Makiko Urabe, Katsuhiko Sato, Yuta Myojin, Akira Doi, Kazuhiro Murai, Sadatsugu Sakane, Yoshinobu Saito, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
Sci Rep. 2021; 11: 3363. Published online 2021 Feb 9. doi: 10.1038/s41598-021-83082-7
PMCID:
PMC7873060
AbstractArticlePDF–11M

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