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Select item 108550401.

Effects of Bradykinin B2 Receptor Ablation from Tyrosine Hydroxylase Cells on Behavioral and Motor Aspects in Male and Female Mice

Thaina Maquedo Franco, Mariana R. Tavares, Leonardo S. Novaes, Carolina D. Munhoz, Jose Eduardo Peixoto-Santos, Ronaldo C. Araujo, Jose Donato, Jr., Michael Bader, Frederick Wasinski

Int J Mol Sci. 2024 Feb; 25(3): 1490. Published online 2024 Jan 25. doi: 10.3390/ijms25031490

PMCID:: PMC10855040

Abstract Article PDF–2.7M

Select item 104997062.

Kinin receptors regulate skeletal muscle regeneration: differential effects for B1 and B2 receptors

Leonardo Martins, Weslley Wallace Amorim, Marcos Fernandes Gregnani, Ronaldo de Carvalho Araújo, Fatimunnisa Qadri, Michael Bader, João Bosco Pesquero

Inflamm Res. 2023; 72(8): 1583–1601. Published online 2023 Jul 18. doi: 10.1007/s00011-023-01766-4

PMCID:: PMC10499706

Abstract Article PDF–8.9M

Select item 68054203.

Tibial post fracture pain is reduced in kinin receptors deficient mice and blunted by kinin receptor antagonists

Vincent Minville, Lionel Mouledous, Acil Jaafar, Réjean Couture, Anne Brouchet, Bernard Frances, Ivan Tack, Jean-Pierre Girolami

J Transl Med. 2019; 17: 346. Published online 2019 Oct 22. doi: 10.1186/s12967-019-2095-9

PMCID:: PMC6805420

Abstract Article PDF–1.4M

Select item 67254434.

Bradykinin Produces Pain Hypersensitivity by Potentiating Spinal Cord Glutamatergic Synaptic Transmission

Haibin Wang, Tatsuro Kohno, Fumimasa Amaya, Gary J. Brenner, Nobuko Ito, Andrew Allchorne, Ru-Rong Ji, Clifford J. Woolf

J Neurosci. 2005 Aug 31; 25(35): 7986–7992. doi: 10.1523/JNEUROSCI.2393-05.2005

PMCID:: PMC6725443

Abstract Article PDF–449K

Select item 66734055.

Bradykinin-Induced Microglial Migration Mediated by B₁-Bradykinin Receptors Depends on Ca²⁺ Influx via Reverse-Mode Activity of the Na⁺/Ca²⁺ Exchanger

Masataka Ifuku, Katrin Färber, Yuko Okuno, Yukiko Yamakawa, Taiki Miyamoto, Christiane Nolte, Vanessa F. Merrino, Satomi Kita, Takahiro Iwamoto, Issei Komuro, Bing Wang, Giselle Cheung, Eiichi Ishikawa, Hiroaki Ooboshi, Michael Bader, Keiji Wada, Helmut Kettenmann, Mami Noda

J Neurosci. 2007 Nov 28; 27(48): 13065–13073. doi: 10.1523/JNEUROSCI.3467-07.2007

PMCID:: PMC6673405

Abstract Article PDF–632K

Select item 66136346.

Kinin-B2 Receptor Activity in Skeletal Muscle Regeneration and Myoblast Differentiation

Janaina M. Alves, Antonio H. Martins, Claudiana Lameu, Talita Glaser, Nawal M. Boukli, Vinicius Bassaneze, Rafael Dariolli, Isis C. Nascimento, Poliana C. M. Martins, Héllio D. N. de Souza, José Eduardo Krieger, Dulce E. Casarini, Vicencia M. Sales, João B. Pesquero, Henning Ulrich

Stem Cell Rev. Author manuscript; available in PMC 2020 Feb 1.

Published in final edited form as: Stem Cell Rev. 2019 Feb; 15(1): 48–58. doi: 10.1007/s12015-018-9850-9

PMCID:: PMC6613634

Abstract Article PDF–1.7M

Select item 65919017.

Malaria infection promotes a selective expression of kinin receptors in murine liver

Priscilla D. S. Ventura, Carolina P. F. Carvalho, Nilana M. T. Barros, Leonardo Martins-Silva, Edilson O. Dantas, Carolina Martinez, Pollyana M. S. Melo, João B. Pesquero, Adriana K. Carmona, Marcia R. Nagaoka, Marcos L. Gazarini

Malar J. 2019; 18: 213. Published online 2019 Jun 24. doi: 10.1186/s12936-019-2846-3

PMCID:: PMC6591901

Abstract Article PDF–6.2M

Select item 64158208.

Cardioprotection via the skin: nociceptor-induced conditioning against cardiac MI in the NIC of time

Xiaoping Ren, Anne E. Roessler, Thomas L. Lynch, 4th, Lauren Haar, Faryal Mallick, Yong Lui, Michael Tranter, Michelle Huan Ren, Wen Rui Xie, Guo-Chang Fan, Jun-Ming Zhang, Evangelia G. Kranias, Ahmad Anjak, Sheryl Koch, Min Jiang, Qing Miao, Yang Wang, Albert Cohen, Jack Rubinstein, Neal L. Weintraub, W. Keith Jones

Am J Physiol Heart Circ Physiol. 2019 Mar 1; 316(3): H543–H553. Published online 2018 Dec 21. doi: 10.1152/ajpheart.00094.2018

PMCID:: PMC6415820

Abstract Article

Select item 63933429.

Increased Reactive Oxygen Species Generation Contributes to the Atherogenic Activity of the B2 Bradykinin Receptor

Alexander Perhal, Stefan Wolf, Yahya F. Jamous, Andreas Langer, Joshua Abd Alla, Ursula Quitterer

Front Med (Lausanne) 2019; 6: 32. Published online 2019 Feb 21. doi: 10.3389/fmed.2019.00032

PMCID:: PMC6393342

Abstract Article PDF–2.5M

Select item 582486910.

Factor XII and uPAR upregulate neutrophil functions to influence wound healing

Evi X. Stavrou, Chao Fang, Kara L. Bane, Andy T. Long, Clément Naudin, Erdem Kucukal, Agharnan Gandhi, Adina Brett-Morris, Michele M. Mumaw, Sudeh Izadmehr, Alona Merkulova, Cindy C. Reynolds, Omar Alhalabi, Lalitha Nayak, Wen-Mei Yu, Cheng-Kui Qu, Howard J. Meyerson, George R. Dubyak, Umut A. Gurkan, Marvin T. Nieman, Anirban Sen Gupta, Thomas Renné, Alvin H. Schmaier

J Clin Invest. 2018 Mar 1; 128(3): 944–959. Published online 2018 Jan 29. doi: 10.1172/JCI92880

PMCID:: PMC5824869

Abstract Article PDF–9.6M

Select item 540809311.

Vascular Kinin B₁ and B₂ Receptors Determine Endothelial Dysfunction through Neuronal Nitric Oxide Synthase

Thássio R. R. Mesquita, Gianne P. Campos-Mota, Virgínia S. Lemos, Jader S. Cruz, Itamar C. G. de Jesus, Enilton A. Camargo, Jorge L. Pesquero, João B. Pesquero, Luciano Dos Santos A. Capettini, Sandra Lauton-Santos

Front Physiol. 2017; 8: 228. Published online 2017 Apr 28. doi: 10.3389/fphys.2017.00228

PMCID:: PMC5408093

Abstract Article PDF–1.7M

Select item 505580812.

Conditional knockout of collecting duct bradykinin B₂ receptors exacerbates angiotensin II-induced hypertension during high salt intake

Libor Kopkan, Zuzana Husková, Šárka Jíchová, Lenka Červenková, Luděk Červenka, Zubaida Saifudeen, Samir S. El-Dahr

Clin Exp Hypertens. Author manuscript; available in PMC 2017 Jan 1.

Published in final edited form as: Clin Exp Hypertens. 2016; 38(1): 1–9. Published online 2015 Jul 7. doi: 10.3109/10641963.2015.1047945

PMCID:: PMC5055808

Abstract Article PDF–1.4M

Select item 487398213.

Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells

Kerstin Göbel, Susann Pankratz, Chloi-Magdalini Asaridou, Alexander M. Herrmann, Stefan Bittner, Monika Merker, Tobias Ruck, Sarah Glumm, Friederike Langhauser, Peter Kraft, Thorsten F. Krug, Johanna Breuer, Martin Herold, Catharina C. Gross, Denise Beckmann, Adelheid Korb-Pap, Michael K. Schuhmann, Stefanie Kuerten, Ioannis Mitroulis, Clemens Ruppert, Marc W. Nolte, Con Panousis, Luisa Klotz, Beate Kehrel, Thomas Korn, Harald F. Langer, Thomas Pap, Bernhard Nieswandt, Heinz Wiendl, Triantafyllos Chavakis, Christoph Kleinschnitz, Sven G. Meuth

Nat Commun. 2016; 7: 11626. Published online 2016 May 18. doi: 10.1038/ncomms11626

PMCID:: PMC4873982

Abstract Article PDF–1.5M

Select item 456681214.

The polyphosphate–factor XII pathway drives coagulation in prostate cancer-associated thrombosis

Katrin F. Nickel, Göran Ronquist, Florian Langer, Linda Labberton, Tobias A. Fuchs, Carsten Bokemeyer, Guido Sauter, Markus Graefen, Nigel Mackman, Evi X. Stavrou, Gunnar Ronquist, Thomas Renné

Blood. 2015 Sep 10; 126(11): 1379–1389. Prepublished online 2015 Jul 7. doi: 10.1182/blood-2015-01-622811

PMCID:: PMC4566812

Abstract Article

Select item 455440915.

Kinin B1 and B2 receptor deficiency protects against obesity induced by a high-fat diet and improves glucose tolerance in mice

Rafael L Morais, Elton D Silva, Vicência M Sales, Rafael Filippelli-Silva, Marcelo A Mori, Michael Bader, João B Pesquero

Diabetes Metab Syndr Obes. 2015; 8: 399–407. Published online 2015 Aug 26. doi: 10.2147/DMSO.S87635

PMCID:: PMC4554409

Abstract Article PDF–1.3M

Select item 391137016.

G Proteins Gα_i1/3 Are Critical Targets for Bordetella pertussis Toxin-Induced Vasoactive Amine Sensitization

Sean A. Diehl, Benjamin McElvany, Rajkumar Noubade, Nathan Seeberger, Brock Harding, Karen Spach, Cory Teuscher

Infect Immun. 2014 Feb; 82(2): 773–782. doi: 10.1128/IAI.00971-13

PMCID:: PMC3911370

Abstract Article PDF–276K

Select item 365166517.

IL-4 and IL-13 inhibit IL-1β and TNF-α induced kinin B₁ and B₂ receptors through a STAT6-dependent mechanism

PPC Souza, AB Brechter, RI Reis, CAS Costa, P Lundberg, UH Lerner

Br J Pharmacol. 2013 May; 169(2): 400–412. Published online 2013 Apr 25. doi: 10.1111/bph.12116

PMCID:: PMC3651665

Abstract Article PDF–1.4M

Select item 362494518.

Angiotensin 1-7 and Mas decrease thrombosis in Bdkrb2^−/− mice by increasing NO and prostacyclin to reduce platelet spreading and glycoprotein VI activation

Chao Fang, Evi Stavrou, Alec A. Schmaier, Nadja Grobe, Mariana Morris, Andrew Chen, Marvin T. Nieman, Gregory N. Adams, Gretchen LaRusch, Yihua Zhou, Matthew L. Bilodeau, Fakhri Mahdi, Mark Warnock, Alvin H. Schmaier

Blood. 2013 Apr 11; 121(15): 3023–3032. Prepublished online 2013 Feb 5. doi: 10.1182/blood-2012-09-459156

Correction in:: Blood. 2014 Mar 6; 123(10): 1622.

PMCID:: PMC3624945

Abstract Article

Select item 362493519.

miR-21 mediates hematopoietic suppression in MDS by activating TGF-β signaling

Tushar D. Bhagat, Li Zhou, Lubomir Sokol, Rachel Kessel, Gisela Caceres, Krishna Gundabolu, Roni Tamari, Shanisha Gordon, Ioannis Mantzaris, Tomasz Jodlowski, Yiting Yu, Xiaohong Jing, Rahul Polineni, Kavi Bhatia, Andrea Pellagatti, Jacqueline Boultwood, Suman Kambhampati, Ulrich Steidl, Cy Stein, Wenjun Ju, Gang Liu, Paraic Kenny, Alan List, Markus Bitzer, Amit Verma

Blood. 2013 Apr 11; 121(15): 2875–2881. Prepublished online 2013 Feb 6. doi: 10.1182/blood-2011-12-397067

PMCID:: PMC3624935

Abstract Article

Select item 357256520.

Exacerbation of DSS-induced colitis in mice lacking kinin B₁ receptors through compensatory up-regulation of kinin B₂ receptors: the role of tight junctions and intestinal homeostasis

R Marcon, RF Claudino, RC Dutra, AF Bento, EC Schmidt, ZL Bouzon, R Sordi, RLT Morais, JB Pesquero, JB Calixto

Br J Pharmacol. 2013 Jan; 168(2): 389–402. Published online 2012 Dec 20. doi: 10.1111/j.1476-5381.2012.02136.x

PMCID:: PMC3572565

Abstract Article PDF–3.5M

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