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Items: 1 to 20 of 137

1.
Loss of TRPM8 Exacerbate Herpes Simplex Keratitis Infection in Mice by Promoting the Infiltration of CD11b+ Ly6G+ Cells and Increasing the Viral Load in the Cornea
Jing Feng, Lingling Yang, Lili Ran, Xia Qi, Xiaolei Wang, Yangyang Zhang, Zongzheng Zou, Ting Liu, Xiaochuan Wang, Yang Yu, Xiaodong Sun, Qingjun Zhou
Invest Ophthalmol Vis Sci. 2023 Dec; 64(15): 24. Published online 2023 Dec 20. doi: 10.1167/iovs.64.15.24
PMCID:
PMC10741096
AbstractArticlePDF–4.0M
2.
Neuronal loss of TRPM8 leads to obesity and glucose intolerance in male mice
D. Liskiewicz, Q. Zhang, C.S. Barthem, M. Jastroch, A. Liskiewicz, N. Khajavi, G. Grandl, C. Coupland, M. Kleinert, C. Garcia-Caceres, A. Novikoff, G. Maity, U. Boehm, M.H. Tschöp, T.D. Müller
Mol Metab. 2023 Jun; 72: 101714. Published online 2023 Mar 24. doi: 10.1016/j.molmet.2023.101714
PMCID:
PMC10106965
AbstractArticlePDF–2.3M
3.
TRPM8 indicates poor prognosis in colorectal cancer patients and its pharmacological targeting reduces tumour growth in mice by inhibiting Wnt/β‐catenin signalling
Ester Pagano, Barbara Romano, Donatella Cicia, Fabio A. Iannotti, Tommaso Venneri, Giuseppe Lucariello, Maria Francesca Nanì, Fabio Cattaneo, Paola De Cicco, Maria D'Armiento, Marcello De Luca, Ruggiero Lionetti, Stefania Lama, Paola Stiuso, Pietro Zoppoli, Geppino Falco, Silvia Marchianò, Stefano Fiorucci, Raffaele Capasso, Vincenzo Di Marzo, Francesca Borrelli, Angelo A. Izzo
Br J Pharmacol. 2023 Jan; 180(2): 235–251. Published online 2022 Oct 17. doi: 10.1111/bph.15960
PMCID:
PMC10092658
AbstractArticlePDF–2.8M
4.
Endogenous Inflammatory Mediators Produced by Injury Activate TRPV1 and TRPA1 Nociceptors to Induce Sexually Dimorphic Cold Pain That Is Dependent on TRPM8 and GFRα3
Chenyu Yang, Shanni Yamaki, Tyler Jung, Brian Kim, Ryan Huyhn, David D. McKemy
J Neurosci. 2023 Apr 12; 43(15): 2803–2814. doi: 10.1523/JNEUROSCI.2303-22.2023
PMCID:
PMC10089246
AbstractArticlePDF–2.4M
5.
Suppressive effects of a transient receptor potential melastatin 8 (TRPM8) agonist on hyperthermia-induced febrile seizures in infant mice
Hiroshi Moriyama, Sadahiro Nomura, Hirochika Imoto, Fumiaki Oka, Yuichi Maruta, Naomasa Mori, Natsumi Fujii, Michiyasu Suzuki, Hideyuki Ishihara
Front Pharmacol. 2023; 14: 1138673. Published online 2023 Mar 9. doi: 10.3389/fphar.2023.1138673
PMCID:
PMC10033885
AbstractArticlePDF–2.5M
6.
Effect of TRPM8 Functional Loss on Corneal Epithelial Wound Healing in Mice
Lili Ran, Jing Feng, Xia Qi, Ting Liu, Benxiang Qi, Kai Jiang, Zhenzhen Zhang, Yang Yu, Qingjun Zhou, Lixin Xie
Invest Ophthalmol Vis Sci. 2023 Jan; 64(1): 19. Published online 2023 Jan 24. doi: 10.1167/iovs.64.1.19
PMCID:
PMC9896868
AbstractArticlePDF–18M
7.
Validation of Six Commercial Antibodies for the Detection of Heterologous and Endogenous TRPM8 Ion Channel Expression
Pablo Hernández-Ortego, Remedios Torres-Montero, Elvira de la Peña, Félix Viana, Jorge Fernández-Trillo
Int J Mol Sci. 2022 Dec; 23(24): 16164. Published online 2022 Dec 18. doi: 10.3390/ijms232416164
PMCID:
PMC9784522
AbstractArticlePDF–4.2M
8.
TRPM8 contributes to liver regeneration via mitochondrial energy metabolism mediated by PGC1α
Xiaohua Lei, Qiang Liu, Wei Qin, Qing Tong, Zhenghao Li, Wendi Xu, Guoxing Liu, Jie Fu, Ju Zhang, Tao Kuang, Yaoli Shao, Chun Liu, Yu Fang, Zhenyu Cao, Likun Yan, Zhiqiang Liu, Siyuan Liu, Hirofumi Yamamoto, Masaki Mori, Xin M. Liang, Xundi Xu
Cell Death Dis. 2022 Dec; 13(12): 1050. Published online 2022 Dec 16. doi: 10.1038/s41419-022-05475-4
Correction in:
Cell Death Dis. 2023 Mar; 14(3): 204.
PMCID:
PMC9758188
AbstractArticlePDF–4.2M
9.
TRPM8 contributes to sex dimorphism by promoting recovery of normal sensitivity in a mouse model of chronic migraine
David Alarcón-Alarcón, David Cabañero, Jorge de Andrés-López, Magdalena Nikolaeva-Koleva, Simona Giorgi, Gregorio Fernández-Ballester, Asia Fernández-Carvajal, Antonio Ferrer-Montiel
Nat Commun. 2022; 13: 6304. Published online 2022 Oct 22. doi: 10.1038/s41467-022-33835-3
PMCID:
PMC9588003
AbstractArticlePDF–1.9M
10.
Transient receptor potential melastatin 8 (TRPM8) is required for nitroglycerin and calcitonin gene-related peptide induced migraine-like pain behaviors in mice
Chao Wei, Brian Kim, David D. McKemy
Pain. Author manuscript; available in PMC 2023 Dec 1.
Published in final edited form as: Pain. 2022 Dec 1; 163(12): 2380–2389. Published online 2022 Mar 29. doi: 10.1097/j.pain.0000000000002635
PMCID:
PMC9519811
ArticlePDF–1.6M
11.
Activation of peripheral TRPM8 mitigates ischemic stroke by topically applied menthol
Shiang-Suo Huang, Hsing-Hui Su, Szu-Yu Chien, Hsin-Yi Chung, Sih-Ting Luo, Yu-Ting Chu, Yi-Hsin Wang, Iona J. MacDonald, Hsun-Hua Lee, Yi-Hung Chen
J Neuroinflammation. 2022; 19: 192. Published online 2022 Jul 27. doi: 10.1186/s12974-022-02553-4
PMCID:
PMC9327358
AbstractArticlePDF–6.6M
12.
Structures of a mammalian TRPM8 in closed state
Cheng Zhao, Yuan Xie, Lizhen Xu, Fan Ye, Ximing Xu, Wei Yang, Fan Yang, Jiangtao Guo
Nat Commun. 2022; 13: 3113. Published online 2022 Jun 3. doi: 10.1038/s41467-022-30919-y
PMCID:
PMC9166780
AbstractArticlePDF–3.8M
13.
Trpm8 Expression in Human and Mouse Castration Resistant Prostate Adenocarcinoma Paves the Way for the Preclinical Development of TRPM8-Based Targeted Therapies
Sacha Genovesi, Riccardo Moro, Beatrice Vignoli, Dario De Felice, Marco Canossa, Rodolfo Montironi, Francesco Giuseppe Carbone, Mattia Barbareschi, Andrea Lunardi, Alessandro Alaimo
Biomolecules. 2022 Feb; 12(2): 193. Published online 2022 Jan 23. doi: 10.3390/biom12020193
PMCID:
PMC8961668
AbstractArticlePDF–63M
14.
In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening
Nunzio Iraci, Carmine Ostacolo, Alicia Medina-Peris, Tania Ciaglia, Anton M. Novoselov, Andrea Altieri, David Cabañero, Asia Fernandez-Carvajal, Pietro Campiglia, Isabel Gomez-Monterrey, Alessia Bertamino, Alexander V. Kurkin
Int J Mol Sci. 2022 Feb; 23(4): 2070. Published online 2022 Feb 13. doi: 10.3390/ijms23042070
PMCID:
PMC8877448
AbstractArticlePDF–4.0M
15.
Rational Design of a Modality‐Specific Inhibitor of TRPM8 Channel against Oxaliplatin‐Induced Cold Allodynia
Aerziguli Aierken, Ya‐Kai Xie, Wenqi Dong, Abuliken Apaer, Jia‐Jia Lin, Zihan Zhao, Shilong Yang, Zhen‐Zhong Xu, Fan Yang
Adv Sci (Weinh) 2021 Nov; 8(22): 2101717. Published online 2021 Oct 17. doi: 10.1002/advs.202101717
PMCID:
PMC8596132
AbstractArticlePDF–6.4M
16.
Suppressive Effects of Transient Receptor Potential Melastatin 8 Agonist on Epileptiform Discharges and Epileptic Seizures
Hiroshi Moriyama, Sadahiro Nomura, Hirochika Imoto, Takao Inoue, Yuichi Fujiyama, Kohei Haji, Yuichi Maruta, Hideyuki Ishihara, Michiyasu Suzuki
Front Pharmacol. 2021; 12: 766782. Published online 2021 Oct 1. doi: 10.3389/fphar.2021.766782
PMCID:
PMC8517222
AbstractArticlePDF–1.5M
17.
Constitutive Phosphorylation as a Key Regulator of TRPM8 Channel Function
Bastián Rivera, Claudio Moreno, Boris Lavanderos, Ji Yeon Hwang, Jorge Fernández-Trillo, Kang-Sik Park, Patricio Orio, Félix Viana, Rodolfo Madrid, María Pertusa
J Neurosci. 2021 Oct 13; 41(41): 8475–8493. doi: 10.1523/JNEUROSCI.0345-21.2021
PMCID:
PMC8513697
AbstractArticlePDF–6.1M
18.
Mapping the expression of transient receptor potential channels across murine placental development
Katrien De Clercq, Vicente Pérez-García, Rieta Van Bree, Federica Pollastro, Karen Peeraer, Thomas Voets, Joris Vriens
Cell Mol Life Sci. 2021 Jun; 78(11): 4993–5014. Published online 2021 Apr 21. doi: 10.1007/s00018-021-03837-3
PMCID:
PMC8233283
AbstractArticlePDF–4.1M
19.
TRPM8 modulates temperature regulation in a sex-dependent manner without affecting cold-induced bone loss
Adriana Lelis Carvalho, Annika Treyball, Daniel J. Brooks, Samantha Costa, Ryan J. Neilson, Michaela R. Reagan, Mary L. Bouxsein, Katherine J. Motyl
PLoS One. 2021; 16(6): e0231060. Published online 2021 Jun 4. doi: 10.1371/journal.pone.0231060
PMCID:
PMC8177490
AbstractArticlePDF–3.9M
20.
Loss of Prdm12 during development, but not in mature nociceptors, causes defects in pain sensation
Mark A. Landy, Megan Goyal, Katherine M. Casey, Chen Liu, Helen C. Lai
Cell Rep. Author manuscript; available in PMC 2021 Apr 15.
Published in final edited form as: Cell Rep. 2021 Mar 30; 34(13): 108913. doi: 10.1016/j.celrep.2021.108913
PMCID:
PMC8048104
AbstractArticlePDF–1.5M

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