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Items: 1 to 20 of 34

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
IFN-λ3 is induced by Leishmania donovani and can inhibit parasite growth in cell line models but not in the mouse model, while it shows a significant association with leishmaniasis in humans
Manjarika De, Soumi Sukla, Seema Bharatiya, Sagar Keshri, Debarati Guha Roy, Sutopa Roy, Debrupa Dutta, Shriya Saha, Sarfaraz Ahmad Ejazi, V. Ravichandiran, Nahid Ali, Mitali Chatterjee, Sreedhar Chinnaswamy
Infect Immun. 2024 Feb; 92(2): e00504-23. Published online 2024 Jan 9. doi: 10.1128/iai.00504-23
PMCID:
PMC10863405
AbstractArticlePDF–1.1M
3.
IFN-λ derived from nonsusceptible enterocytes acts on tuft cells to limit persistent norovirus
Harshad Ingle, Heyde Makimaa, Somya Aggarwal, Hongju Deng, Lynne Foster, Yuhao Li, Elizabeth A. Kennedy, Stefan T. Peterson, Craig B. Wilen, Sanghyun Lee, Mehul S. Suthar, Megan T. Baldridge
Sci Adv. 2023 Sep; 9(37): eadi2562. Published online 2023 Sep 13. doi: 10.1126/sciadv.adi2562
PMCID:
PMC10499323
AbstractArticlePDF–1.4M
4.
Nasally delivered interferon-λ protects mice against infection by SARS-CoV-2 variants including Omicron
Zhenlu Chong, Courtney E. Karl, Peter J. Halfmann, Yoshihiro Kawaoka, Emma S. Winkler, Shamus P. Keeler, Michael J. Holtzman, Jinsheng Yu, Michael S. Diamond
Cell Rep. 2022 May 10; 39(6): 110799. Published online 2022 Apr 21. doi: 10.1016/j.celrep.2022.110799
PMCID:
PMC9021357
AbstractArticlePDF–6.2M
5.
Murine Type III interferons are functionally redundant and correlate with bacterial burden during influenza/bacterial super-infection
Helen E. Rich, Danielle Antos, Collin C. McCourt, Wen Quan Zheng, Louis J. Devito, Kevin J. McHugh, Radha Gopal, Jieru Wang, John F. Alcorn
PLoS One. 2021; 16(10): e0255309. Published online 2021 Oct 7. doi: 10.1371/journal.pone.0255309
PMCID:
PMC8496871
AbstractArticlePDF–1.4M
6.
Protective cellular and mucosal immune responses following nasal administration of a whole gamma-irradiated influenza A (subtype H1N1) vaccine adjuvanted with interleukin-28B in a mouse model
Ailar Sabbaghi, Mohsen Zargar, Mohammad Reza Zolfaghari, Farahnaz Motamedi-Sedeh, Amir Ghaemi
Arch Virol. 2021; 166(2): 545–557. Published online 2021 Jan 6. doi: 10.1007/s00705-020-04900-3
PMCID:
PMC7787640
AbstractArticlePDF–1.2M
7.
Interleukin-28B dampens protease-induced lung inflammation via IL-25 and TSLP inhibition in epithelial cells
Bailing Yan, Jinying Gao, Jia Guo, Dong Yang, Dan Li
Sci Rep. 2020; 10: 20973. Published online 2020 Dec 1. doi: 10.1038/s41598-020-77844-y
PMCID:
PMC7708501
AbstractArticlePDF–3.0M
8.
Selective Interferon Responses of Intestinal Epithelial Cells Minimize Tumor Necrosis Factor Alpha Cytotoxicity
Jacob A. Van Winkle, David A. Constant, Lena Li, Timothy J. Nice
J Virol. 2020 Nov; 94(21): e00603-20. Prepublished online 2020 Aug 26. Published online 2020 Oct 14. doi: 10.1128/JVI.00603-20
PMCID:
PMC7565621
AbstractArticlePDF–4.2M
9.
Type I and III interferons disrupt lung epithelial repair during recovery from viral infection
Jack Major, Stefania Crotta, Miriam Llorian, Teresa M. McCabe, Hans Henrik Gad, Simon L. Priestnall, Rune Hartmann, Andreas Wack
Science. 2020 Aug 7; 369(6504): 712–717. Published online 2020 Jun 11. doi: 10.1126/science.abc2061
PMCID:
PMC7292500
AbstractArticlePDF–591K
10.
Type III interferons disrupt the lung epithelial barrier upon viral recognition
Achille Broggi, Sreya Ghosh, Benedetta Sposito, Roberto Spreafico, Fabio Balzarini, Antonino Lo Cascio, Nicola Clementi, Maria De Santis, Nicasio Mancini, Francesca Granucci, Ivan Zanoni
Science. 2020 Aug 7; 369(6504): 706–712. Published online 2020 Jun 11. doi: 10.1126/science.abc3545
PMCID:
PMC7292499
AbstractArticlePDF–913K
11.
Disruption of Type III Interferon (IFN) Genes Ifnl2 and Ifnl3 Recapitulates Loss of the Type III IFN Receptor in the Mucosal Antiviral Response
Stefan T. Peterson, Elizabeth A. Kennedy, Pamela H. Brigleb, Gwen M. Taylor, Kelly Urbanek, Traci L. Bricker, Sanghyun Lee, Haina Shin, Terence S. Dermody, Adrianus C. M. Boon, Megan T. Baldridge
J Virol. 2019 Nov 15; 93(22): e01073-19. Prepublished online 2019 Aug 28. Published online 2019 Oct 29. doi: 10.1128/JVI.01073-19
PMCID:
PMC6819914
AbstractArticlePDF–405K
12.
IFN-λ Decreases Murid Herpesvirus-4 Infection of the Olfactory Epithelium but Fails to Prevent Virus Reactivation in the Vaginal Mucosa
Sophie Jacobs, Caroline Zeippen, Fanny Wavreil, Laurent Gillet, Thomas Michiels
Viruses. 2019 Aug; 11(8): 757. Published online 2019 Aug 16. doi: 10.3390/v11080757
PMCID:
PMC6722623
AbstractArticlePDF–11M
13.
A secreted viral non-structural protein determines intestinal norovirus pathogenesis
Sanghyun Lee, Hejun Liu, Craig B. Wilen, Zoi E. Sychev, Chandni Desai, Barry L. Hykes, Jr, Robert C. Orchard, Broc T. McCune, Ki-Wook Kim, Timothy J. Nice, Scott A. Handley, Megan T. Baldridge, Gaya K. Amarasinghe, Herbert W. Virgin
Cell Host Microbe. Author manuscript; available in PMC 2020 Jun 12.
Published in final edited form as: Cell Host Microbe. 2019 Jun 12; 25(6): 845–857.e5. Published online 2019 May 23. doi: 10.1016/j.chom.2019.04.005
PMCID:
PMC6622463
AbstractArticlePDF–1.1M
14.
Interferon-λ3 Promotes Epithelial Defense and Barrier Function Against Cryptosporidium parvum Infection
Sylvia H. Ferguson, Derek M. Foster, Barbara Sherry, Scott T. Magness, Dahlia M. Nielsen, Jody L. Gookin
Cell Mol Gastroenterol Hepatol. 2019; 8(1): 1–20. Published online 2019 Mar 5. doi: 10.1016/j.jcmgh.2019.02.007
PMCID:
PMC6510929
AbstractArticlePDF–4.4M
15.
Gestational stage and IFN-λ signaling regulate ZIKV infection in utero
Brett W. Jagger, Jonathan J. Miner, Bin Cao, Nitin Arora, Amber M. Smith, Attila Kovacs, Indira U. Mysorekar, Carolyn B. Coyne, Michael S. Diamond
Cell Host Microbe. Author manuscript; available in PMC 2018 Sep 13.
Published in final edited form as: Cell Host Microbe. 2017 Sep 13; 22(3): 366–376.e3. doi: 10.1016/j.chom.2017.08.012
PMCID:
PMC5647680
AbstractArticlePDF–1.7M
16.
Interleukin-28B dampens airway inflammation through up-regulation of natural killer cell-derived IFN-γ
Bailing Yan, Feng Chen, Lijun Xu, Yanshi Wang, Xuefu Wang
Sci Rep. 2017; 7: 3556. Published online 2017 Jun 15. doi: 10.1038/s41598-017-03856-w
PMCID:
PMC5472588
AbstractArticlePDF–6.5M
17.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
18.
IL-28B down-regulates regulatory T cells but does not improve the protective immunity following tuberculosis subunit vaccine immunization
Yanping Luo, Xingming Ma, Xun Liu, Xiaoling Lu, Hongxia Niu, Hongjuan Yu, Chunxiang Bai, Jinxiu Peng, Qiaoyang Xian, Yong Wang, Bingdong Zhu
Int Immunol. 2016 Feb; 28(2): 77–85. Published online 2015 Oct 31. doi: 10.1093/intimm/dxv061
PMCID:
PMC4885220
AbstractArticle
19.
Interferon-? and interleukin-22 cooperate for the induction of interferon-stimulated genes and control of rotavirus infection
Pedro P. Hernández, Tanel Mahlakoiv, Ines Yang, Vera Schwierzeck, Nam Nguyen, Fabian Guendel, Konrad Gronke, Bernhard Ryffel, Christoph Hoelscher, Laure Dumoutier, Jean-Christophe Renauld, Sebastian Suerbaum, Peter Staeheli, Andreas Diefenbach
Nat Immunol. Author manuscript; available in PMC 2016 Jan 1.
Published in final edited form as: Nat Immunol. 2015 Jul; 16(7): 698–707. Published online 2015 May 25. doi: 10.1038/ni.3180
PMCID:
PMC4589158
AbstractArticlePDF–2.5M
20.
Interferon Lambda Upregulates IDO1 Expression in Respiratory Epithelial Cells After Influenza Virus Infection
Julie M. Fox, Jackelyn M. Crabtree, Leo K. Sage, S. Mark Tompkins, Ralph A. Tripp
J Interferon Cytokine Res. 2015 Jul 1; 35(7): 554–562. doi: 10.1089/jir.2014.0052
PMCID:
PMC4507134
AbstractArticlePDF–595K

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