PMC Links for GEO Profiles (Select 87308332) - PMC

Select item 75295581.

EEF1A2 and ERN2 could potentially discriminate metastatic status of mediastinal lymph node in lung adenocarcinomas harboring EGFR 19Del/L858R mutations

Lei Xia, Hui Wang, He Xiao, Baohua Lan, Jie Liu, Zhenzhou Yang

Thorac Cancer. 2020 Oct; 11(10): 2755–2766. Published online 2020 Sep 3. doi: 10.1111/1759-7714.13554

PMCID:: PMC7529558

Abstract Article PDF–1.3M

Select item 74273272.

Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases

Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger

Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001

PMCID:: PMC7427327

Abstract Article

Select item 70416863.

IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress

Michael J. Grey, Eva Cloots, Mariska S. Simpson, Nicole LeDuc, Yevgeniy V. Serebrenik, Heidi De Luca, Delphine De Sutter, Phi Luong, Jay R. Thiagarajah, Adrienne W. Paton, James C. Paton, Markus A. Seeliger, Sven Eyckerman, Sophie Janssens, Wayne I. Lencer

J Cell Biol. 2020 Feb 3; 219(2): e201904048. Published online 2020 Jan 27. doi: 10.1083/jcb.201904048

PMCID:: PMC7041686

Abstract Article PDF–3.7M

Select item 66357834.

XBP1S Regulates MUC5B in a Promoter Variant–Dependent Pathway in Idiopathic Pulmonary Fibrosis Airway Epithelia

Gang Chen, Carla M. P. Ribeiro, Ling Sun, Kenichi Okuda, Takafumi Kato, Rodney C. Gilmore, Mary B. Martino, Hong Dang, Aiman Abzhanova, Jennifer M. Lin, Emily A. Hull-Ryde, Allison S. Volmer, Scott H. Randell, Alessandra Livraghi-Butrico, Yingfeng Deng, Philipp E. Scherer, Barry R. Stripp, Wanda K. O’Neal, Richard C. Boucher

Am J Respir Crit Care Med. 2019 Jul 15; 200(2): 220–234. Published online 2019 Jul 15. doi: 10.1164/rccm.201810-1972OC

Correction in:: Am J Respir Crit Care Med. 2019 Oct 15; 200(8): 1074.

PMCID:: PMC6635783

Abstract Article PDF–2.6M

Select item 65945515.

PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling

Adnan Shami Shah, Alex G. Batrouni, Dongsung Kim, Amith Punyala, Wendy Cao, Chun Han, Michael L. Goldberg, Marcus B. Smolka, Jeremy M. Baskin

Cell Rep. Author manuscript; available in PMC 2019 Jun 26.

Published in final edited form as: Cell Rep. 2019 May 14; 27(7): 2157–2170.e8. doi: 10.1016/j.celrep.2019.04.060

PMCID:: PMC6594551

Abstract Article PDF–1.4M

Select item 60777226.

Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy

Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115

PMCID:: PMC6077722

Abstract Article PDF–2.4M

Select item 50365277.

Panorama of ancient metazoan macromolecular complexes

Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Nature. Author manuscript; available in PMC 2016 Sep 26.

Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877

PMCID:: PMC5036527

Abstract Article PDF–4.7M

Select item 35174618.

Direct Association of Unfolded Proteins with Mammalian ER Stress Sensor, IRE1β

Daisuke Oikawa, Akira Kitamura, Masataka Kinjo, Takao Iwawaki

PLoS One. 2012; 7(12): e51290. Published online 2012 Dec 7. doi: 10.1371/journal.pone.0051290

PMCID:: PMC3517461

Abstract Article PDF–1.2M

Select item 31780599.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 294516810.

Variation at the NFATC2 Locus Increases the Risk of Thiazolidinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study

Swneke D. Bailey, Changchun Xie, Ron Do, Alexandre Montpetit, Rafael Diaz, Viswanathan Mohan, Bernard Keavney, Salim Yusuf, Hertzel C. Gerstein, James C. Engert, Sonia Anand, on behalf of the DREAM investigators

Diabetes Care. 2010 Oct; 33(10): 2250–2253. Published online 2010 Jul 13. doi: 10.2337/dc10-0452

PMCID:: PMC2945168

Abstract Article PDF–153K

Select item 289646411.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

Select item 277583212.

Gene-centric Association Signals for Lipids and Apolipoproteins Identified via the HumanCVD BeadChip

Philippa J. Talmud, Fotios Drenos, Sonia Shah, Tina Shah, Jutta Palmen, Claudio Verzilli, Tom R. Gaunt, Jacky Pallas, Ruth Lovering, Kawah Li, Juan Pablo Casas, Reecha Sofat, Meena Kumari, Santiago Rodriguez, Toby Johnson, Stephen J. Newhouse, Anna Dominiczak, Nilesh J. Samani, Mark Caulfield, Peter Sever, Alice Stanton, Denis C. Shields, on behalf of the ASCOT investigators, Sandosh Padmanabhan, Olle Melander, Claire Hastie, Christian Delles, on behalf of the NORDIL investigators, Shah Ebrahim, Michael G. Marmot, George Davey Smith, Debbie A. Lawlor, Patricia B. Munroe, for the BRIGHT Consortium, Ian N. Day, Mika Kivimaki, John Whittaker, Steve E. Humphries, Aroon D. Hingorani

Am J Hum Genet. 2009 Nov 13; 85(5): 628–642. doi: 10.1016/j.ajhg.2009.10.014

PMCID:: PMC2775832

Abstract Article PDF–2.8M

Select item 156619013.

The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response

Jiahai Zhou, Chuan Yin Liu, Sung Hoon Back, Robert L. Clark, Daniel Peisach, Zhaohui Xu, Randal J. Kaufman

Proc Natl Acad Sci U S A. 2006 Sep 26; 103(39): 14343–14348. Published online 2006 Sep 14. doi: 10.1073/pnas.0606480103

PMCID:: PMC1566190

Abstract Article PDF–1.9M

Select item 117089914.

Cloning of mammalian Ire1 reveals diversity in the ER stress responses.

X Z Wang, H P Harding, Y Zhang, E M Jolicoeur, M Kuroda, D Ron

EMBO J. 1998 Oct 1; 17(19): 5708–5717. doi: 10.1093/emboj/17.19.5708

PMCID:: PMC1170899

Summary PDF–540K

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