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Select item 111862871.

TFAP2A downregulation mediates tumor-suppressive effect of miR-8072 in triple-negative breast cancer via inhibiting SNAI1 transcription

Yujie Fang, Yali Wang, Hongning Ma, Yuqi Guo, Rongrong Xu, Xixi Chen, Xuehua Chen, Ye Lv, Pu Li, Yujing Gao

Breast Cancer Res. 2024; 26: 103. Published online 2024 Jun 18. doi: 10.1186/s13058-024-01858-x

PMCID:: PMC11186287

Abstract Article PDF–12M

Select item 110079092.

Endomucin selectively regulates vascular endothelial growth factor receptor-2 endocytosis through its interaction with AP2

Issahy Cano, Melissa Wild, Urvi Gupta, Suman Chaudhary, Yin Shan Eric Ng, Magali Saint-Geniez, Patricia A. D’Amore, Zhengping Hu

Cell Commun Signal. 2024; 22: 225. Published online 2024 Apr 11. doi: 10.1186/s12964-024-01606-w

Correction in:: Cell Commun Signal. 2024; 22: 311.

PMCID:: PMC11007909

Abstract Article PDF–8.8M

Select item 108664413.

Potential prognosis and immunotherapy predictor TFAP2A in pan-cancer

Chenxi Niu, Haixuan Wen, Shutong Wang, Guang Shu, Maonan Wang, Hanxi Yi, Ke Guo, Qiong Pan, Gang Yin

Aging (Albany NY) 2024 Jan 31; 16(2): 1021–1048. Published online 2024 Jan 23. doi: 10.18632/aging.205225

PMCID:: PMC10866441

Abstract Article PDF–4.7M

Select item 104501644.

Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors

Ke Liu, Yuqing Xiao, Linyao Gan, Weifang Li, Jin Zhang, Jinrong Min

Nucleic Acids Res. 2023 Aug 25; 51(15): 8270–8282. Published online 2023 Jul 6. doi: 10.1093/nar/gkad583

PMCID:: PMC10450164

Abstract Article PDF–1.6M

Select item 102768775.

Epigenetically modified AP-2α by DNA methyltransferase facilitates glioma immune evasion by upregulating PD-L1 expression

Shengwen Long, Guixiang Huang, Mi Ouyang, Kai Xiao, Hao Zhou, Anyi Hou, Zhiwei Li, Zhe Zhong, Dongmei Zhong, Qinghao Wang, Shuanglin Xiang, Xiaofeng Ding

Cell Death Dis. 2023 Jun; 14(6): 365. Published online 2023 Jun 17. doi: 10.1038/s41419-023-05878-x

PMCID:: PMC10276877

Abstract Article PDF–6.1M

Select item 101704876.

TFAP2A promotes cervical cancer via a positive feedback pathway with PD‑L1

Junyuan Yang, Yang Gao, Sinjie Yao, Shimeng Wan, Hongbing Cai

Oncol Rep. 2023 Jun; 49(6): 114. Published online 2023 Apr 20. doi: 10.3892/or.2023.8551

PMCID:: PMC10170487

Abstract Article PDF–13M

Select item 99992357.

Transcription factor AP-2α activates RNA polymerase III–directed transcription and tumor cell proliferation by controlling expression of c-MYC and p53

Juan Wang, Qiyue Chen, Feixia Peng, Shasha Zhao, Cheng Zhang, Xiaoye Song, Deen Yu, Zhongyu Wu, Jiannan Du, Hongwei Ni, Huan Deng, Wensheng Deng

J Biol Chem. 2023 Mar; 299(3): 102945. Published online 2023 Jan 25. doi: 10.1016/j.jbc.2023.102945

PMCID:: PMC9999235

Abstract Article PDF–1.9M

Select item 97979888.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Abstract Article PDF–6.9M

Select item 97080869.

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

Martina Oravcová, Minghua Nie, Nicola Zilio, Shintaro Maeda, Yasaman Jami-Alahmadi, Eros Lazzerini-Denchi, James A Wohlschlegel, Helle D Ulrich, Takanori Otomo, Michael N Boddy

eLife. 2022; 11: e79676. Published online 2022 Nov 14. doi: 10.7554/eLife.79676

PMCID:: PMC9708086

Abstract Article PDF–8.5M

Select item 956995510.

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation

Yulemi Gonzalez Quesada, Luc DesGroseillers

Int J Mol Sci. 2022 Oct; 23(19): 11588. Published online 2022 Sep 30. doi: 10.3390/ijms231911588

PMCID:: PMC9569955

Abstract Article PDF–2.1M

Select item 954034511.

The in vivo Interaction Landscape of Histones H3.1 and H3.3

Robert Siddaway, Scott Milos, Étienne Coyaud, Hwa Young Yun, Shahir M. Morcos, Sanja Pajovic, Eric I. Campos, Brian Raught, Cynthia Hawkins

Mol Cell Proteomics. 2022 Oct; 21(10): 100411. Published online 2022 Sep 9. doi: 10.1016/j.mcpro.2022.100411

PMCID:: PMC9540345

Abstract Article PDF–3.9M

Select item 949171312.

FBXO42 facilitates Notch signaling activation and global chromatin relaxation by promoting K63-linked polyubiquitination of RBPJ

Hua Jiang, Weixiang Bian, Yue Sui, Huanle Li, Han Zhao, Wenqi Wang, Xu Li

Sci Adv. 2022 Sep; 8(38): eabq4831. Published online 2022 Sep 21. doi: 10.1126/sciadv.abq4831

PMCID:: PMC9491713

Abstract Article PDF–12M

Select item 948418613.

Transcription factor AP2 enhances malignancy of non-small cell lung cancer through upregulation of USP22 gene expression

Ting Sun, Keqiang Zhang, Wendong Li, Yunze Liu, Rajendra P. Pangeni, Aimin Li, Leonidas Arvanitis, Dan J. Raz

Cell Commun Signal. 2022; 20: 147. Published online 2022 Sep 19. doi: 10.1186/s12964-022-00946-9

PMCID:: PMC9484186

Abstract Article PDF–2.4M

Select item 929024114.

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer

Annamaria Salvati, Viola Melone, Assunta Sellitto, Francesca Rizzo, Roberta Tarallo, Tuula A. Nyman, Giorgio Giurato, Giovanni Nassa, Alessandro Weisz

Breast Cancer Res. 2022; 24: 52. Published online 2022 Jul 18. doi: 10.1186/s13058-022-01547-7

PMCID:: PMC9290241

Abstract Article PDF–8.2M

Select item 927928515.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 911973616.

OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization

Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti

Science. Author manuscript; available in PMC 2022 Sep 11.

Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983

PMCID:: PMC9119736

Abstract Article PDF–3.3M

Select item 884482717.

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase

Zhifen Zhou, Yujing Li, Huimin Xu, Xiaowei Xie, Zibin He, Song Lin, Ruofei Li, Shouheng Jin, Jun Cui, Hai Hu, Feng Liu, Su Wu, Wenbin Ma, Zhou Songyang

iScience. 2022 Feb 18; 25(2): 103813. Published online 2022 Jan 25. doi: 10.1016/j.isci.2022.103813

PMCID:: PMC8844827

Abstract Article PDF–6.0M

Select item 862939018.

ATRX proximal protein associations boast roles beyond histone deposition

William A. Scott, Erum Z. Dhanji, Boris J. A. Dyakov, Ema S. Dreseris, Jonathon S. Asa, Laura J. Grange, Mila Mirceta, Christopher E. Pearson, Grant S. Stewart, Anne-Claude Gingras, Eric I. Campos

PLoS Genet. 2021 Nov; 17(11): e1009909. Published online 2021 Nov 15. doi: 10.1371/journal.pgen.1009909

PMCID:: PMC8629390

Abstract Article PDF–4.0M

Select item 845768919.

Family based and case–control designs reveal an association of TFAP2A in nonsyndromic cleft lip only among Vietnamese population

Duc Minh Nguyen, Satoshi Suzuki, Hideto Imura, Teruyuki Niimi, Hiroo Furukawa, Thanh‐Van Ta, Son Minh Tong, Tra Thu Nguyen, Loc Nguyen Gia Pham, Duy Le Tran, Nagato Natsume

Mol Genet Genomic Med. 2021 Sep; 9(9): e1754. Published online 2021 Jul 26. doi: 10.1002/mgg3.1754

PMCID:: PMC8457689

Abstract Article PDF–488K

Select item 841679820.

AP-2α-mediated Activation of E2F and EZH2 Drives Melanoma Metastasis

Jeffrey R. White, Dakota T. Thompson, Kelsey E. Koch, Boris S. Kiriazov, Anna C. Beck, Dana M. van der Heide, Benjamin G. Grimm, Mikhail V. Kulak, Ronald J. Weigel

Cancer Res. Author manuscript; available in PMC 2022 Mar 1.

Published in final edited form as: Cancer Res. 2021 Sep 1; 81(17): 4455–4470. Published online 2021 Jul 1. doi: 10.1158/0008-5472.CAN-21-0772

PMCID:: PMC8416798

Abstract Article PDF–3.5M

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