PMC Links for GEO Profiles (Select 87632403) - PMC

Jessica Petiti, Ymera Pignochino, Aurora Schiavon, Emilia Giugliano, Enrico Berrino, Giorgia Giordano, Federico Itri, Matteo Dragani, Daniela Cilloni, Marco Lo Iacono

Int J Mol Sci. 2024 Apr; 25(7): 3631. Published online 2024 Mar 24. doi: 10.3390/ijms25073631

PMCID:: PMC11011776

Abstract Article PDF–785K

Select item 109560464.

ZNF692 regulates nucleolar morphology by interacting with NPM1 and modifying its self-assembly properties

Isabella N. Brown, Arlene Levario, Chunhui Jiang, Weronika Stachera, Enrique Rodriguez, Yi-Heng Hao, Jeffrey B. Woodruff, M.Carmen Lafita-Navarro, Maralice Conacci-Sorrell

J Biol Chem. 2024 Mar; 300(3): 105773. Published online 2024 Feb 19. doi: 10.1016/j.jbc.2024.105773

PMCID:: PMC10956046

Abstract Article PDF–3.5M

Select item 109073895.

Mutations highly specific for secondary AML are associated with poor outcomes in ELN favorable risk NPM1-mutated AML

Onyee Chan, Najla Al Ali, Hammad Tashkandi, Austin Ellis, Somedeb Ball, Justin Grenet, Caroline Hana, Yehuda Deutsch, Ling Zhang, Mohammad Hussaini, Jinming Song, Seongseok Yun, Chetasi Talati, Andrew Kuykendall, Eric Padron, Alison Walker, Gail Roboz, Pinkal Desai, David Sallman, Kendra Sweet, Rami Komrokji, Jeffrey Lancet

Blood Adv. 2024 Mar 12; 8(5): 1075–1083. Published online 2024 Jan 5. doi: 10.1182/bloodadvances.2023011173

PMCID:: PMC10907389

Abstract Article PDF–1.7M

Select item 108578046.

NPM1-Mutated Acute Myeloid Leukemia: Recent Developments and Open Questions

Sanjay S. Patel

Pathobiology. 2024 Feb; 91(1): 18–29. Published online 2023 Mar 21. doi: 10.1159/000530253

PMCID:: PMC10857804

Abstract Article

Select item 108252077.

AURKA inhibition induces Ewing’s sarcoma apoptosis and ferroptosis through NPM1/YAP1 axis

Huimou Chen, Jing Hu, Xilin Xiong, Hongling Chen, Biaojun Lin, Yusong Chen, Yang Li, Di Cheng, Zhihua Li

Cell Death Dis. 2024 Jan; 15(1): 99. Published online 2024 Jan 29. doi: 10.1038/s41419-024-06485-0

PMCID:: PMC10825207

Abstract Article PDF–6.1M

Select item 107649588.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 107502949.

MANF Promotes Unexplained Recurrent Miscarriages by Interacting with NPM1 and Downregulating Trophoblast Cell Migration and Invasion

Yuan Fang, Junhui Zhang, Damin Zhu, Qiong Mei, Ting Liao, Huiru Cheng, Ye He, Yunxia Cao, Zhaolian Wei

Int J Biol Sci. 2024; 20(1): 296–311. Published online 2024 Jan 1. doi: 10.7150/ijbs.85378

PMCID:: PMC10750294

Abstract Article PDF–9.1M

Select item 1061767310.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 1056587611.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 1054764712.

Immortalization-upregulated protein promotes pancreatic cancer progression by regulating NPM1/FHL1-mediated cell-cycle-checkpoint protein activity

Qiankun Luo, Yanfeng Pan, Qiang Fu, Xu Zhang, Shuai Zhou, Pengfei Yu, Huiyuan Tian, Pan Liu, Song Chen, Hongwei Zhang, Tao Qin

Cell Biol Toxicol. 2023; 39(5): 2069–2087. Published online 2022 Feb 10. doi: 10.1007/s10565-022-09695-4

PMCID:: PMC10547647

Abstract Article PDF–9.5M

Select item 1049649413.

DDX24 Mutation Alters NPM1 Phase Behavior and Disrupts Nucleolar Homeostasis in Vascular Malformations

Haopei Zhang, Qiuyue Chen, Qianqian Zhang, Hairun Gan, Hanjie Li, Shoudeng Chen, Hong Shan, Pengfei Pang, Huanhuan He

Int J Biol Sci. 2023; 19(13): 4123–4138. Published online 2023 Aug 6. doi: 10.7150/ijbs.84097

PMCID:: PMC10496494

Abstract Article PDF–7.9M

Select item 1047646614.

Nuclear PLD1 combined with NPM1 induces gemcitabine resistance through tumorigenic IL7R in pancreatic adenocarcinoma

Danqi Fu, Jingrui Yan, Zhaoyu Zhang, Yang Liu, Xiaoqing Ma, Jinsheng Ding, Shengyu Yang, Ran Zhao, Antao Chang, Chuntao Gao, Jing Liu, Tiansuo Zhao, Xiuchao Wang, Chongbiao Huang, Song Gao, Ying Ma, Bo Tang, Yukuan Feng, Hongwei Wang, Jihui Hao

Cancer Biol Med. 2023 Aug 15; 20(8): 599–626. Published online 2023 Jun 27. doi: 10.20892/j.issn.2095-3941.2023.0039

PMCID:: PMC10476466

Abstract Article PDF–4.1M

Select item 1033388415.

Large‐scale phosphomimetic screening identifies phospho‐modulated motif‐based protein interactions

Johanna Kliche, Dimitriya Hristoforova Garvanska, Leandro Simonetti, Dilip Badgujar, Doreen Dobritzsch, Jakob Nilsson, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2023 Jul; 19(7): e11164. Published online 2023 May 23. doi: 10.15252/msb.202211164

PMCID:: PMC10333884

Abstract Article PDF–5.0M

Select item 1028411716.

Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry

Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang

Anal Chem. Author manuscript; available in PMC 2023 Jun 21.

Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986

PMCID:: PMC10284117

Abstract Article PDF–2.5M

Select item 1023742217.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1016456418.

The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing

Yingxiao Chen, Yanping Li, Roselyn S Dai, Jonathan C Savage, Ujwal Shinde, John Klimek, Larry L David, Emma A Young, Markus Hafner, Rosalie C Sears, Xiao-Xin Sun, Mu-Shui Dai

Nucleic Acids Res. 2023 May 8; 51(8): 3934–3949. Published online 2023 Mar 13. doi: 10.1093/nar/gkad140

PMCID:: PMC10164564

Abstract Article PDF–3.8M

Select item 1016023219.

Long noncoding RNA LINC01088 inhibits esophageal squamous cell carcinoma progression by targeting the NPM1-HDM2-p53 axis: LINC01088 inhibits esophageal squamous cell carcinoma progression

Fan Liang, Qiuli Luo, Haibo Han, Jianzhi Zhang, Yue Yang, Jinfeng Chen

Acta Biochim Biophys Sin (Shanghai) 2023 Mar; 55(3): 367–381. Published online 2023 Mar 17. doi: 10.3724/abbs.2023021

PMCID:: PMC10160232

Abstract Article PDF–2.9M

Select item 1015161520.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120