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Select item 110730131.

NSun2 regulates aneurysm formation by promoting autotaxin expression and T cell recruitment

Yutong Miao, Yang Zhao, Lulu Han, Xiaolong Ma, Jiacheng Deng, Juan Yang, Silin Lü, Fangyu Shao, Wei Kong, Wengong Wang, Qingbo Xu, Xian Wang, Juan Feng

Cell Mol Life Sci. 2021 Feb; 78(4): 1709–1727. Published online 2020 Jul 30. doi: 10.1007/s00018-020-03607-7

PMCID:: PMC11073013

Abstract Article PDF–2.5M

Select item 107924272.

Autotaxin–lysophosphatidic acid receptor 5 axis evokes endothelial dysfunction via reactive oxygen species signaling

Anna Janovicz, Aliz Majer, Mónika Kosztelnik, Miklós Geiszt, Jerold Chun, Satoshi Ishii, Gábor József Tigyi, Zoltán Benyó, Éva Ruisanchez

Exp Biol Med (Maywood) 2023 Oct; 248(20): 1887–1894. Published online 2023 Oct 14. doi: 10.1177/15353702231199081

PMCID:: PMC10792427

Abstract Article PDF–1.0M

Select item 106294993.

The autotaxin-LPA axis promotes membrane trafficking and secretion in yolk sac visceral endoderm cells

Seiichi Koike, Kazuko Keino-Masu, Yoko Tanimoto, Satoru Takahashi, Masayuki Masu

Biol Open. 2023 Nov 15; 12(11): bio060081. Published online 2023 Oct 30. doi: 10.1242/bio.060081

PMCID:: PMC10629499

Abstract Article PDF–3.4M

Select item 103640774.

E2F7 drives Autotaxin/Enpp2 transcription via chromosome looping: Repression by p53 in murine but not human carcinomas

Kuan-Hung Lin, Sue Chin Lee, Mélanie A. Dacheux, Derek D. Norman, Andrea Balogh, Mitul Bavaria, Hsinyu Lee, Gabor Tigyi

FASEB J. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: FASEB J. 2023 Jul; 37(7): e23058. doi: 10.1096/fj.202300838R

PMCID:: PMC10364077

Abstract Article PDF–2.6M

Select item 99141075.

Endothelial Specific Deletion of Autotaxin Improves Stroke Outcomes

Susmita Bhattarai, Utsab Subedi, Shrivats Manikandan, Sudha Sharma, Papori Sharma, Chloe Miller, Md Shenuarin Bhuiyan, Srivatsan Kidambi, Vassilis Aidinis, Hong Sun, Sumitra Miriyala, Manikandan Panchatcharam

Cells. 2023 Feb; 12(3): 511. Published online 2023 Feb 3. doi: 10.3390/cells12030511

PMCID:: PMC9914107

Abstract Article PDF–3.5M

Select item 94901006.

Hepatocyte-Secreted Autotaxin Exacerbates Nonalcoholic Fatty Liver Disease Through Autocrine Inhibition of the PPARα/FGF21 Axis

Han Qiu, Erfei Song, Yue Hu, Tengfei Li, Kam Ching Ku, Cunchuan Wang, Bernard M.Y. Cheung, Lai Yee Cheong, Qin Wang, Xiaoping Wu, Ruby L.C. Hoo, Yong Wang, Aimin Xu

Cell Mol Gastroenterol Hepatol. 2022; 14(5): 1003–1023. Published online 2022 Aug 2. doi: 10.1016/j.jcmgh.2022.07.012

PMCID:: PMC9490100

Abstract Article PDF–5.2M

Select item 94211777.

Dach1 transcription factor regulates the expression of peripheral node addressin and lymphocyte trafficking in lymph nodes

Arisa Shintani, Shoko Fukai, Reika Nobusawa, Kanako Taniguchi, Tomohiro Hatatani, Hayato Nagai, Tomohiro Sakai, Takuji Yoshimura, Masayuki Miyasaka, Haruko Hayasaka

Curr Res Immunol. 2022; 3: 175–185. Published online 2022 Aug 21. doi: 10.1016/j.crimmu.2022.08.008

PMCID:: PMC9421177

Abstract Article PDF–13M

Select item 83951748.

Inhibition of Autotaxin and Lysophosphatidic Acid Receptor 5 Attenuates Neuroinflammation in LPS-Activated BV-2 Microglia and a Mouse Endotoxemia Model

Lisha Joshi, Ioanna Plastira, Eva Bernhart, Helga Reicher, Alexander Triebl, Harald C. Köfeler, Wolfgang Sattler

Int J Mol Sci. 2021 Aug; 22(16): 8519. Published online 2021 Aug 7. doi: 10.3390/ijms22168519

PMCID:: PMC8395174

Abstract Article PDF–3.4M

Select item 83132399.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 784364610.

LPA signaling acts as a cell-extrinsic mechanism to initiate cilia disassembly and promote neurogenesis

Huai-Bin Hu, Zeng-Qing Song, Guang-Ping Song, Sen Li, Hai-Qing Tu, Min Wu, Yu-Cheng Zhang, Jin-Feng Yuan, Ting-Ting Li, Pei-Yao Li, Yu-Ling Xu, Xiao-Lin Shen, Qiu-Ying Han, Ai-Ling Li, Tao Zhou, Jerold Chun, Xue-Min Zhang, Hui-Yan Li

Nat Commun. 2021; 12: 662. Published online 2021 Jan 28. doi: 10.1038/s41467-021-20986-y

PMCID:: PMC7843646

Abstract Article PDF–5.3M

Select item 777409411.

Klf14 is an imprinted transcription factor that regulates placental growth

Erik Koppes, Ben Shaffer, Elena Sadovsky, Katherine Himes, Yaacov Barak, Yoel Sadovsky, J. Richard Chaillet

Placenta. Author manuscript; available in PMC 2020 Dec 31.

Published in final edited form as: Placenta. 2019 Dec; 88: 61–67. Published online 2019 Sep 27. doi: 10.1016/j.placenta.2019.09.013

PMCID:: PMC7774094

Abstract Article PDF–834K

Select item 774411212.

Autotaxin Inhibition Reduces Cardiac Inflammation and Mitigates Adverse Cardiac Remodeling After Myocardial Infarction

Himi Tripathi, Ahmed Al-Darraji, Mohamed Abo-Aly, Hsuan Peng, Elica Shokri, Lakshman Chelvarajan, Renee Donahue, Bryana M. Levitan, Erhe Gao, Gabriela Hernandez, Andrew J. Morris, Susan S. Smyth, Ahmed Abdel-Latif

J Mol Cell Cardiol. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: J Mol Cell Cardiol. 2020 Dec; 149: 95–114. Published online 2020 Oct 2. doi: 10.1016/j.yjmcc.2020.09.011

PMCID:: PMC7744112

Abstract Article PDF–3.2M

Select item 711766913.

Genetic deletion of Autotaxin from CD11b⁺ cells decreases the severity of experimental autoimmune encephalomyelitis

Ioanna Ninou, Ioanna Sevastou, Christiana Magkrioti, Eleanna Kaffe, George Stamatakis, Spyros Thivaios, George Panayotou, Junken Aoki, George Kollias, Vassilis Aidinis

PLoS One. 2020; 15(4): e0226050. Published online 2020 Apr 2. doi: 10.1371/journal.pone.0226050

PMCID:: PMC7117669

Abstract Article PDF–2.8M

Select item 681737514.

Osteoclast-derived Autotaxin, a distinguishing factor for inflammatory bone loss

Sacha FLAMMIER, Olivier PEYRUCHAUD, Fanny BOURGUILLAULT, François DUBOEUF, Jean-Luc DAVIGNON, Derek D NORMAN, Sylvie ISAAC, Hubert MAROTTE, Gabor TIGYI, Irma MACHUCA-GAYET, Fabienne COURY

Arthritis Rheumatol. Author manuscript; available in PMC 2020 Nov 1.

Published in final edited form as: Arthritis Rheumatol. 2019 Nov; 71(11): 1801–1811. Published online 2019 Sep 30. doi: 10.1002/art.41005

PMCID:: PMC6817375

Abstract Article

Select item 655639715.

Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST

Yoko Nakano, Susan Wiechert, Botond Bánfi

Cell Rep. Author manuscript; available in PMC 2019 Jun 9.

Published in final edited form as: Cell Rep. 2019 Apr 16; 27(3): 860–871.e8. doi: 10.1016/j.celrep.2019.03.072

PMCID:: PMC6556397

Abstract Article PDF–2.3M

Select item 640456516.

Autotaxin determines colitis severity in mice and is secreted by B cells in the colon

Songbai Lin, Abedul Haque, Reben Raeman, Leilei Guo, Peijian He, Timothy L. Denning, Bassel El-Rayes, Wouter H. Moolenaar, C. Chris Yun

FASEB J. 2019 Mar; 33(3): 3623–3635. Published online 2018 Nov 27. doi: 10.1096/fj.201801415RR

PMCID:: PMC6404565

Abstract Article

Select item 636687017.

Adipose-derived autotaxin regulates inflammation and steatosis associated with diet-induced obesity

J. Anthony Brandon, Maria Kraemer, Julia Vandra, Suchismita Halder, Margo Ubele, Andrew J. Morris, Susan S. Smyth

PLoS One. 2019; 14(2): e0208099. Published online 2019 Feb 7. doi: 10.1371/journal.pone.0208099

PMCID:: PMC6366870

Abstract Article PDF–3.1M

Select item 616831018.

Deficiency of alkaline SMase enhances dextran sulfate sodium-induced colitis in mice with upregulation of autotaxin

Ping Zhang, Ying Chen, Tao Zhang, Jiang Zhu, Lei Zhao, Jianshuang Li, Guangzhi Wang, Yongchun Li, Shuchang Xu, Åke Nilsson, Rui-Dong Duan

J Lipid Res. 2018 Oct; 59(10): 1841–1850. Published online 2018 Aug 7. doi: 10.1194/jlr.M084285

PMCID:: PMC6168310

Abstract Article PDF–2.0M

Select item 616830419.

Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism

Kenneth D’Souza, Carine Nzirorera, Andrew M. Cowie, Geena P. Varghese, Purvi Trivedi, Thomas O. Eichmann, Dipsikha Biswas, Mohamed Touaibia, Andrew J. Morris, Vassilis Aidinis, Daniel A. Kane, Thomas Pulinilkunnil, Petra C. Kienesberger

J Lipid Res. 2018 Oct; 59(10): 1805–1817. Published online 2018 Aug 2. doi: 10.1194/jlr.M082008