PMC Links for GEO Profiles (Select 87911783) - PMC

Anthony C. Varca, Dominick Casalena, Wai Cheung Chan, Bin Hu, Robert S. Magin, Rebekka M. Roberts, Xiaoxi Liu, He Zhu, Hyuk-Soo Seo, Sirano Dhe-Paganon, Jarrod A. Marto, Douglas Auld, Sara J. Buhrlage

Cell Chem Biol. Author manuscript; available in PMC 2022 Dec 16.

Published in final edited form as: Cell Chem Biol. 2021 Dec 16; 28(12): 1758–1771.e13. Published online 2021 Jun 14. doi: 10.1016/j.chembiol.2021.05.012

PMCID:: PMC9473745

Abstract Article PDF–2.3M

Select item 90565254.

Deubiquitylase OTUD3 prevents Parkinson’s disease through stabilizing iron regulatory protein 2

Fengju Jia, Hongchang Li, Qian Jiao, Chaonan Li, Lin Fu, Chunping Cui, Hong Jiang, Lingqiang Zhang

Cell Death Dis. 2022 Apr; 13(4): 418. Published online 2022 Apr 30. doi: 10.1038/s41419-022-04704-0

PMCID:: PMC9056525

Abstract Article PDF–6.3M

Select item 86366405.

Nicotine-mediated OTUD3 downregulation inhibits VEGF-C mRNA decay to promote lymphatic metastasis of human esophageal cancer

Meng Wang, Yue Li, Yunyun Xiao, Muwen Yang, Jinxin Chen, Yunting Jian, Xin Chen, Dongni Shi, Xiangfu Chen, Ying Ouyang, Lingzhi Kong, Xinjian Huang, Jiewen Bai, Chuyong Lin, Libing Song

Nat Commun. 2021; 12: 7006. Published online 2021 Dec 1. doi: 10.1038/s41467-021-27348-8

PMCID:: PMC8636640

Abstract Article PDF–7.4M

Select item 83865236.

The deubiquitinase OTUD3 stabilizes ACTN4 to drive growth and metastasis of hepatocellular carcinoma

Peiyi Xie, Yanglin Chen, Hongfei Zhang, Guichao Zhou, Qing Chao, Jiangwen Wang, Yue Liu, Jiayu Fang, Jing Xie, Jing Zhen, Zhiyuan Wang, Liang Hao, Da Huang

Aging (Albany NY) 2021 Aug 15; 13(15): 19317–19338. Published online 2021 Aug 10. doi: 10.18632/aging.203293

PMCID:: PMC8386523

Abstract Article PDF–3.0M

Select item 82929097.

SPOP and OTUD7A Control EWS–FLI1 Protein Stability to Govern Ewing Sarcoma Growth

Siyuan Su, Jianfeng Chen, Yao Jiang, Ying Wang, Tamara Vital, Jiaming Zhang, Christian Laggner, Kong T. Nguyen, Zhichuan Zhu, Alex W. Prevatte, Natalie K. Barker, Laura E. Herring, Ian J. Davis, Pengda Liu

Adv Sci (Weinh) 2021 Jul; 8(14): 2004846. Published online 2021 Jun 1. doi: 10.1002/advs.202004846

PMCID:: PMC8292909

Abstract Article PDF–4.0M

Select item 81650308.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 81202279.

KAT6A, a novel regulator of β-catenin, promotes tumorigenicity and chemoresistance in ovarian cancer by acetylating COP1

Wenxue Liu, Zhiyan Zhan, Meiying Zhang, Bowen Sun, Qiqi Shi, Fei Luo, Mingda Zhang, Weiwei Zhang, Yanli Hou, Xiuying Xiao, Yanxin Li, Haizhong Feng

Theranostics. 2021; 11(13): 6278–6292. Published online 2021 Apr 15. doi: 10.7150/thno.57455

PMCID:: PMC8120227

Abstract Article PDF–2.7M

Select item 791983610.

OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase

Hyo Jin Kim, Jongchan Kim

Int J Mol Sci. 2021 Feb; 22(4): 1936. Published online 2021 Feb 16. doi: 10.3390/ijms22041936

PMCID:: PMC7919836

Abstract Article PDF–5.0M

Select item 756062711.

Ubiquitin ligase CHIP regulates OTUD3 stability and suppresses tumour metastasis in lung cancer

Pengfei Zhang, Chaonan Li, Hongchang Li, Lin Yuan, Hongmiao Dai, Zhiqiang Peng, Zhikang Deng, Zhijie Chang, Chun-Ping Cui, Lingqiang Zhang

Cell Death Differ. 2020 Nov; 27(11): 3177–3195. Published online 2020 Jun 1. doi: 10.1038/s41418-020-0571-7

PMCID:: PMC7560627

Abstract Article PDF–6.1M

Select item 739109512.

miR-520h Stimulates Drug Resistance to Paclitaxel by Targeting the OTUD3-PTEN Axis in Breast Cancer

Wenwen Geng, Haiyun Song, Qianqian Zhao, Ke Dong, Qian Pu, Haidong Gao, Yanrong Lv

Biomed Res Int. 2020; 2020: 9512793. Published online 2020 May 9. doi: 10.1155/2020/9512793

PMCID:: PMC7391095

Abstract Article PDF–1.8M

Select item 731022813.

Tumor suppressor OTUD3 induces growth inhibition and apoptosis by directly deubiquitinating and stabilizing p53 in invasive breast carcinoma cells

Qian Pu, Yan-rong Lv, Ke Dong, Wen-wen Geng, Hai-dong Gao

BMC Cancer. 2020; 20: 583. Published online 2020 Jun 22. doi: 10.1186/s12885-020-07069-9

PMCID:: PMC7310228

Abstract Article PDF–2.0M

Select item 716998314.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 706433815.

Distinct regulatory ribosomal ubiquitylation events are reversible and hierarchically organized

Danielle M Garshott, Elayanambi Sundaramoorthy, Marilyn Leonard, Eric J Bennett

eLife. 2020; 9: e54023. Published online 2020 Feb 3. doi: 10.7554/eLife.54023

PMCID:: PMC7064338

Abstract Article PDF–4.5M

Select item 660664916.

The deubiquitylase OTUD3 stabilizes GRP78 and promotes lung tumorigenesis

Tongde Du, Hongchang Li, Yongsheng Fan, Lin Yuan, Xiaodan Guo, Qiong Zhu, Yuying Yao, Xin Li, Chunlei Liu, Xinhe Yu, Zhaofei Liu, Chun-Ping Cui, Chuanchun Han, Lingqiang Zhang

Nat Commun. 2019; 10: 2914. Published online 2019 Jul 2. doi: 10.1038/s41467-019-10824-7

PMCID:: PMC6606649

Abstract Article PDF–4.7M

Select item 589620217.

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability

Dominika Kwasna, Syed Arif Abdul Rehman, Jayaprakash Natarajan, Stephen Matthews, Ross Madden, Virginia De Cesare, Simone Weidlich, Satpal Virdee, Ivan Ahel, Ian Gibbs-Seymour, Yogesh Kulathu

Mol Cell. 2018 Apr 5; 70(1): 150–164.e6. doi: 10.1016/j.molcel.2018.02.023

PMCID:: PMC5896202

Abstract Article

Select item 567858118.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 485024719.

Non-hydrolyzable Diubiquitin Probes Reveal Linkage-Specific Reactivity of Deubiquitylating Enzymes Mediated by S2 Pockets

Dennis Flierman, Gerbrand J. van der Heden van Noort, Reggy Ekkebus, Paul P. Geurink, Tycho E.T. Mevissen, Manuela K. Hospenthal, David Komander, Huib Ovaa

Cell Chem Biol. 2016 Apr 21; 23(4): 472–482. Published online 2016 Apr 21. doi: 10.1016/j.chembiol.2016.03.009

PMCID:: PMC4850247

Abstract Article

Select item 417683420.

Assembly, analysis and architecture of atypical ubiquitin chains

Manuela K. Hospenthal, Stefan M.V. Freund, David Komander

Nat Struct Mol Biol. Author manuscript; available in PMC 2014 Sep 27.

Published in final edited form as: Nat Struct Mol Biol. 2013 May; 20(5): 555–565. Published online 2013 Apr 7. doi: 10.1038/nsmb.2547

PMCID:: PMC4176834

Abstract Article PDF–3.4M

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