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Select item 111481841.

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

YiQing Lü, Tiffany Cho, Saptaparna Mukherjee, Carmen Florencia Suarez, Nicolas S Gonzalez-Foutel, Ahmad Malik, Sebastien Martinez, Dzana Dervovic, Robin Hyunseo Oh, Ellen Langille, Khalid N Al-Zahrani, Lisa Hoeg, Zhen Yuan Lin, Ricky Tsai, Geraldine Mbamalu, Varda Rotter, Patricia Ashton-Prolla, Jason Moffat, Lucia Beatriz Chemes, Anne-Claude Gingras, Moshe Oren, Daniel Durocher, Daniel Schramek

Mol Syst Biol. 2024 Jun; 20(6): 719–740. Published online 2024 Apr 5. doi: 10.1038/s44320-024-00032-x

PMCID:: PMC11148184

Abstract Article PDF–8.1M

Select item 110916662.

Transcription Factor E2F7 Hampers the Killing Effect of NK Cells against Colorectal Cancer Cells via Activating RAD18 Transcription

Bingdong Jiang, Binghua Yan, Hengjin Yang, He Geng, Peng Li

J Microbiol Biotechnol. 2024 Apr 28; 34(4): 920–929. Published online 2023 Nov 17. doi: 10.4014/jmb.2308.08026

PMCID:: PMC11091666

Abstract Article PDF–5.0M

Select item 109216823.

p53/E2F7 axis promotes temozolomide chemoresistance in glioblastoma multiforme

Jiao Meng, Wei Qian, Zhenkun Yang, Lingli Gong, Daxing Xu, Hongbo Huang, Xinyi Jiang, Zhening Pu, Ying Yin, Jian Zou

BMC Cancer. 2024; 24: 317. Published online 2024 Mar 7. doi: 10.1186/s12885-024-12017-y

PMCID:: PMC10921682

Abstract Article PDF–4.9M

Select item 107987224.

E2F7 serves as a potential prognostic biomarker for lung adenocarcinoma

Shengcheng Lin, Xiangyang Yu, Haojie Yan, Yafei Xu, Kai Ma, Xiaoliang Wang, Yeqing Liu, Ahuan Xie, Zhentao Yu

Medicine (Baltimore) 2024 Jan 19; 103(3): e34342. Published online 2024 Jan 19. doi: 10.1097/MD.0000000000034342

PMCID:: PMC10798722

Abstract Article PDF–3.8M

Select item 103640775.

E2F7 drives Autotaxin/Enpp2 transcription via chromosome looping: Repression by p53 in murine but not human carcinomas

Kuan-Hung Lin, Sue Chin Lee, Mélanie A. Dacheux, Derek D. Norman, Andrea Balogh, Mitul Bavaria, Hsinyu Lee, Gabor Tigyi

FASEB J. Author manuscript; available in PMC 2024 Jul 1.

Published in final edited form as: FASEB J. 2023 Jul; 37(7): e23058. doi: 10.1096/fj.202300838R

PMCID:: PMC10364077

Abstract Article PDF–2.6M

Select item 103447436.

Circ_0010235 confers cisplatin resistance in lung cancer by upregulating E2F7 through absorbing miR‐379‐5p

Lifei Wang, Dongchang Wang, Zhen Xu, Yali Qiu, Gang Chen, Furong Tan

Thorac Cancer. 2023 Jul; 14(20): 1946–1957. Published online 2023 Jun 5. doi: 10.1111/1759-7714.14941

PMCID:: PMC10344743

Abstract Article PDF–4.4M

Select item 102354377.

VIRMA promotes nasopharyngeal carcinoma, tumorigenesis, and metastasis by upregulation of E2F7 in an m6A-dependent manner

Zi-Qi Zheng, Zhuo-Hui Huang, Ye-Lin Liang, Wei-Hong Zheng, Cheng Xu, Zhi-Xuan Li, Na Liu, Pan-Yang Yang, Ying-Qin Li, Jun Ma, Ying Sun, Ling-Long Tang, Denghui Wei

J Biol Chem. 2023 May; 299(5): 104677. Published online 2023 Apr 5. doi: 10.1016/j.jbc.2023.104677

PMCID:: PMC10235437

Abstract Article PDF–6.9M

Select item 99184588.

Adding pieces to the puzzle of differentiated-to-anaplastic thyroid cancer evolution: the oncogene E2F7

Mila Gugnoni, Eugenia Lorenzini, Italo Faria do Valle, Daniel Remondini, Gastone Castellani, Federica Torricelli, Elisabetta Sauta, Benedetta Donati, Moira Ragazzi, Francesco Ghini, Simonetta Piana, Alessia Ciarrocchi, Gloria Manzotti

Cell Death Dis. 2023 Feb; 14(2): 99. Published online 2023 Feb 10. doi: 10.1038/s41419-023-05603-8

PMCID:: PMC9918458

Abstract Article PDF–6.8M

Select item 98042699.

E2F7 enhances hepatocellular carcinoma growth by preserving the SP1/SOX4/Anillin axis via repressing miRNA‐383‐5p transcription

Fengjie Hao, Nan Wang, Yifan Zhang, Wen Xu, Yongjun Chen, Xiaochun Fei, Junqing Wang

Mol Carcinog. 2022 Nov; 61(11): 975–988. Published online 2022 Aug 4. doi: 10.1002/mc.23454

PMCID:: PMC9804269

Abstract Article PDF–8.8M

Select item 970599210.

LINC00174 Facilitates Proliferation and Migration of Colorectal Cancer Cells via MiR-3127-5p/ E2F7 Axis

Yuhong Ma, Yuzhen Li, Yuanyuan Tang, Ning Tang, Dengke Wang, Xiaofei Li

J Microbiol Biotechnol. 2021 Aug 28; 31(8): 1098–1108. Published online 2021 Jun 14. doi: 10.4014/jmb.2103.03001

PMCID:: PMC9705992

Abstract Article PDF–20M

Select item 938803211.

High expression of E2F transcription factors 7: An independent predictor of poor prognosis in patients with lung adenocarcinoma

Yu Zhang, Lan Lyu, Wei Wang, Liwei Zhang

Medicine (Baltimore) 2022 Aug 19; 101(33): e29253. Published online 2022 Aug 19. doi: 10.1097/MD.0000000000029253

PMCID:: PMC9388032

Abstract Article PDF–2.8M

Select item 936044312.

Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner

Lucía García-Gutiérrez, Emma Fallahi, Nourhan Aboud, Niall Quinn, David Matallanas

Cell Death Dis. 2022 Aug; 13(8): 692. Published online 2022 Aug 8. doi: 10.1038/s41419-022-05147-3

PMCID:: PMC9360443

Abstract Article PDF–5.8M

Select item 886646113.

SAPCD2 promotes neuroblastoma progression by altering the subcellular distribution of E2F7

Zi-Mu Zhang, Hai-Bo Cao, Zhi-Heng Li, Ran Zhuo, Yan-Fang Tao, Xiao-Lu Li, Gen Li, Xin-Mei Liao, Fang Fang, Yi Xie, Di Wu, Hai-Rong Wang, Jian-Wei Wang, Yan-Ling Chen, Juan-Juan Yu, Si-Qi Jia, Ran-Dong Yang, Xin-Yi Guo, Yang Yang, Chen-Xi Feng, Yun-Yun Xu, Guang-Hui Qian, Jian Pan

Cell Death Dis. 2022 Feb; 13(2): 174. Published online 2022 Feb 23. doi: 10.1038/s41419-022-04624-z

PMCID:: PMC8866461

Abstract Article PDF–6.6M

Select item 875541914.

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation

Yuzheng Zhou, Rong Zheng, Sixu Liu, Cyrollah Disoma, Ashuai Du, Shiqin Li, Zongpeng Chen, Zijun Dong, Yongxing Zhang, Sijia Li, Pinjia Liu, Aroona Razzaq, Xuan Chen, Yujie Liao, Siyi Tao, Yuxin Liu, Lunan Xu, Qianjun Zhang, Jian Peng, Xu Deng, Shanni Li, Taijiao Jiang, Zanxian Xia

J Biol Chem. 2022 Feb; 298(2): 101584. Published online 2022 Jan 13. doi: 10.1016/j.jbc.2022.101584

PMCID:: PMC8755419

Abstract Article PDF–3.5M

Select item 856452015.

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair

Maria Pilar Sanchez-Bailon, Soo-Youn Choi, Elizabeth R. Dufficy, Karan Sharma, Gavin S. McNee, Emma Gunnell, Kelly Chiang, Debashish Sahay, Sarah Maslen, Grant S. Stewart, J. Mark Skehel, Ingrid Dreveny, Clare C. Davies

Nat Commun. 2021; 12: 6313. Published online 2021 Nov 2. doi: 10.1038/s41467-021-26413-6

PMCID:: PMC8564520

Abstract Article PDF–2.3M

Select item 831454716.

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation

Ruona Shi, Xue Shi, Dajiang Qin, Shibing Tang, Michiel Vermeulen, Xiaofei Zhang

Cell Biosci. 2021; 11: 146. Published online 2021 Jul 27. doi: 10.1186/s13578-021-00659-5

PMCID:: PMC8314547

Abstract Article PDF–3.7M

Select item 816503017.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 800904818.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 790864019.

Identification of E2F transcription factor 7 as a novel potential biomarker for oral squamous cell carcinoma

Ping Zhou, Lei Xiao, Xiaonan Xu

Head Face Med. 2021; 17: 7. Published online 2021 Feb 26. doi: 10.1186/s13005-021-00258-2

PMCID:: PMC7908640

Abstract Article PDF–3.4M

Select item 767151320.

MiR-424-5p regulates cell cycle and inhibits proliferation of hepatocellular carcinoma cells by targeting E2F7

Yichao Zhao, Chaoqian Zhu, Qing Chang, Peng Peng, Jie Yang, Chunmei Liu, Yang Liu, Xiaonan Chen, Yuanguang Liu, Ran Cheng, Yijie Wu, Xiaotang Wu, Liang Hu, Jun Yin

PLoS One. 2020; 15(11): e0242179. Published online 2020 Nov 17. doi: 10.1371/journal.pone.0242179

PMCID:: PMC7671513

Abstract Article PDF–1.7M

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