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Items: 1 to 20 of 119

1.
Comparative interactome analysis of α-arrestin families in human and Drosophila
Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam
eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328
PMCID:
PMC10945707
AbstractArticlePDF–2.8M
2.
Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma
Suzannah G. Miller, Maria Hoh, Christopher C. Ebmeier, Jian Wei Tay, Natalie G. Ahn
Mol Biol Cell. 2024 Mar 1; 35(3): ar31. Published online 2024 Jan 29. doi: 10.1091/mbc.E23-06-0255
PMCID:
PMC10916866
AbstractArticlePDF–4.7M
3.
Divergent regulation of α-arrestin ARRDC3 function by ubiquitination
Helen Wedegaertner, Oye Bosompra, Irina Kufareva, JoAnn Trejo
Mol Biol Cell. 2023 Aug 1; 34(9): ar93. Published online 2023 Aug 1. doi: 10.1091/mbc.E23-02-0055
PMCID:
PMC10398895
AbstractArticlePDF–1.9M
4.
Palmitic acid negatively regulates tumor suppressor PTEN through T366 phosphorylation and protein degradation
Dongmei Bai, Yong Wu, Poonamjot Deol, Yumiko Nobumori, Qi Zhou, Frances M. Sladek, Xuan Liu
Cancer Lett. Author manuscript; available in PMC 2023 Jul 6.
Published in final edited form as: Cancer Lett. 2021 Jan 1; 496: 127–133. Published online 2020 Oct 9. doi: 10.1016/j.canlet.2020.10.007
PMCID:
PMC10325098
AbstractArticlePDF–1.2M
5.
Cytoplasmic YAP1‐mediated ESCRT‐III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer
Yan Guo, Yuqing Cui, Yangyang Li, Xiaoying Jin, Dandan Wang, Mengxia Lei, Fengzhi Chen, Yali Liu, Jinwen Xu, Guanyu Yao, Guangchun Zeng, Xuesong Chen
Cancer Commun (Lond) 2023 May; 43(5): 582–612. Published online 2023 Apr 2. doi: 10.1002/cac2.12417
PMCID:
PMC10174091
AbstractArticlePDF–22M
6.
Down-regulation of WWP2 aggravates Type 2 diabetes mellitus-induced vascular endothelial injury through modulating ubiquitination and degradation of DDX3X
Shilong You, Jiaqi Xu, Zeyu Yin, Boquan Wu, Pengbo Wang, Mingjun Hao, Cheng Cheng, Mengke Liu, Yuanhui Zhao, Pengyu Jia, Hongkun Jiang, Da Li, Liu Cao, Xingang Zhang, Ying Zhang, Yingxian Sun, Naijin Zhang
Cardiovasc Diabetol. 2023; 22: 107. Published online 2023 May 6. doi: 10.1186/s12933-023-01818-3
PMCID:
PMC10164326
AbstractArticlePDF–12M
7.
Avidity-Based Method for the Efficient Generation of Monoubiquitinated Recombinant Proteins
Spencer L. Nelson, Yunan Li, Yue Chen, Lalit Deshmukh
J Am Chem Soc. 2023 Apr 12; 145(14): 7748–7752. Published online 2023 Apr 3. doi: 10.1021/jacs.3c01943
PMCID:
PMC10103170
AbstractArticlePDF–6.4M
8.
A Semisynthetic Approach to the Analysis of Tumor Suppressor PTEN Ubiquitination
Reina Iwase, Daniel R. Dempsey, Samuel D. Whedon, Hanjie Jiang, Brad A. Palanski, Bedphiny Deng, Philip A. Cole
J Am Chem Soc. Author manuscript; available in PMC 2024 Mar 22.
Published in final edited form as: J Am Chem Soc. 2023 Mar 22; 145(11): 6039–6044. Published online 2023 Mar 10. doi: 10.1021/jacs.2c13871
PMCID:
PMC10071500
AbstractArticlePDF–1.2M
9.
lncRNA BREA2 promotes metastasis by disrupting the WWP2-mediated ubiquitination of Notch1
Zhen Zhang, Yun-xin Lu, Fangzhou Liu, Lingjie Sang, Chengyu Shi, Shaofang Xie, Weixiang Bian, Jie-cheng Yang, Zuozhen Yang, Lei Qu, Shi-yi Chen, Jun Li, Lu Yang, Qingfeng Yan, Wenqi Wang, Peifen Fu, Jianzhong Shao, Xu Li, Aifu Lin
Proc Natl Acad Sci U S A. 2023 Feb 21; 120(8): e2206694120. Published online 2023 Feb 16. doi: 10.1073/pnas.2206694120
PMCID:
PMC9974429
AbstractArticlePDF–9.9M
10.
WWP2 drives the progression of gastric cancer by facilitating the ubiquitination and degradation of LATS1 protein
Jianping Zou, Ling Zhou, Yi Le, Zhi Fang, Min Zhong, Fengting Nie, Xianpin Wei, Xiaomei Zhang, Zhen Chen, Lingling Cai, Heng Wang, Jianping Xiong, Ziling Fang, Xiaojun Xiang
Cell Commun Signal. 2023; 21: 38. Published online 2023 Feb 17. doi: 10.1186/s12964-023-01050-2
PMCID:
PMC9938551
AbstractArticlePDF–11M
11.
WWP2 ameliorates oxidative stress and inflammation in atherosclerotic mice through regulation of PDCD4/HO-1 pathway: WWP2 interacted with PDCD4 ameliorates AS
Xingye Wang, Lu Ma, Songlin Zhang, Qiang Song, Xumei He, Jun Wang
Acta Biochim Biophys Sin (Shanghai) 2022 Aug; 54(8): 1057–1067. Published online 2022 Aug 16. doi: 10.3724/abbs.2022091
PMCID:
PMC9828489
AbstractArticlePDF–2.7M
12.
HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation
Jingsheng Yuan, Tao Lv, Jian Yang, Zhenru Wu, Lvnan Yan, Jiayin Yang, Yujun Shi, Li Jiang
Cell Mol Gastroenterol Hepatol. 2023; 15(2): 307–325. Published online 2022 Oct 14. doi: 10.1016/j.jcmgh.2022.10.005
PMCID:
PMC9772558
AbstractArticlePDF–8.2M
13.
The E3 ubiquitin ligase WWP2 regulates pro-fibrogenic monocyte infiltration and activity in heart fibrosis
Huimei Chen, Gabriel Chew, Nithya Devapragash, Jui Zhi Loh, Kevin Y. Huang, Jing Guo, Shiyang Liu, Elisabeth Li Sa Tan, Shuang Chen, Nicole Gui Zhen Tee, Masum M. Mia, Manvendra K. Singh, Aihua Zhang, Jacques Behmoaras, Enrico Petretto
Nat Commun. 2022; 13: 7375. Published online 2022 Nov 30. doi: 10.1038/s41467-022-34971-6
PMCID:
PMC9712659
AbstractArticlePDF–4.6M
14.
The role of E3 ubiquitin ligase WWP2 and the regulation of PARP1 by ubiquitinated degradation in acute lymphoblastic leukemia
Xinxin Lu, Xinyue Huang, Haiqi Xu, Saien Lu, Shilong You, Jiaqi Xu, Qianru Zhan, Chao Dong, Ning Zhang, Ying Zhang, Liu Cao, Xingang Zhang, Naijin Zhang, Lijun Zhang
Cell Death Discov. 2022; 8: 421. Published online 2022 Oct 18. doi: 10.1038/s41420-022-01209-9
PMCID:
PMC9579143
AbstractArticlePDF–4.5M
15.
miR-328-5p Induces Human Intervertebral Disc Degeneration by Targeting WWP2
Jing Yan, Lun-Gang Wu, Ming Zhang, Tao Fang, Wei Pan, Jia-Li Zhao, Quan Zhou
Oxid Med Cell Longev. 2022; 2022: 3511967. Published online 2022 Sep 29. doi: 10.1155/2022/3511967
PMCID:
PMC9537005
AbstractArticlePDF–1.6M
16.
A WWP2–PTEN–KLF5 signaling axis regulates odontoblast differentiation and dentinogenesis in mice
Jing Fu, Xiaobo Zhang, Huiwen Zheng, Guobin Yang, Zhi Chen, Guohua Yuan
J Biol Chem. 2022 Aug; 298(8): 102220. Published online 2022 Jul 1. doi: 10.1016/j.jbc.2022.102220
PMCID:
PMC9358474
AbstractArticlePDF–3.7M
17.
Lysosomal protein transmembrane 5 promotes lung-specific metastasis by regulating BMPR1A lysosomal degradation
Bo Jiang, Xiaozhi Zhao, Wei Chen, Wenli Diao, Meng Ding, Haixiang Qin, Binghua Li, Wenmin Cao, Wei Chen, Yao Fu, Kuiqiang He, Jie Gao, Mengxia Chen, Tingsheng Lin, Yongming Deng, Chao Yan, Hongqian Guo
Nat Commun. 2022; 13: 4141. Published online 2022 Jul 16. doi: 10.1038/s41467-022-31783-6
PMCID:
PMC9288479
AbstractArticlePDF–16M
18.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
19.
Enzymatic analysis of WWP2 E3 ubiquitin ligase using protein microarrays identifies autophagy-related substrates
Hanjie Jiang, Claire Y. Chiang, Zan Chen, Sara Nathan, Gabriel D’Agostino, Joao A. Paulo, Guang Song, Heng Zhu, Sandra B. Gabelli, Philip A. Cole
J Biol Chem. 2022 May; 298(5): 101854. Published online 2022 Mar 21. doi: 10.1016/j.jbc.2022.101854
PMCID:
PMC9034101
AbstractArticlePDF–3.7M
20.
CFTR interactome mapping using the mammalian membrane two‐hybrid high‐throughput screening system
Sang Hyun Lim, Jamie Snider, Liron Birimberg‐Schwartz, Wan Ip, Joana C Serralha, Hugo M Botelho, Miquéias Lopes‐Pacheco, Madalena C Pinto, Mohamed Taha Moutaoufik, Mara Zilocchi, Onofrio Laselva, Mohsen Esmaeili, Max Kotlyar, Anna Lyakisheva, Priscilla Tang, Lucía López Vázquez, Indira Akula, Farzaneh Aboualizadeh, Victoria Wong, Ingrid Grozavu, Teuta Opacak‐Bernardi, Zhong Yao, Meg Mendoza, Mohan Babu, Igor Jurisica, Tanja Gonska, Christine E Bear, Margarida D Amaral, Igor Stagljar
Mol Syst Biol. 2022 Feb; 18(2): e10629. Published online 2022 Feb 14. doi: 10.15252/msb.202110629
PMCID:
PMC8842165
AbstractArticlePDF–3.0M

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