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Select item 106650021.

RGMa collapses the neuronal actin barrier against disease-implicated protein and exacerbates ALS

Mikito Shimizu, Naoyuki Shiraishi, Satoru Tada, Tsutomu Sasaki, Goichi Beck, Seiichi Nagano, Makoto Kinoshita, Hisae Sumi, Tomoyuki Sugimoto, Yoko Ishida, Toru Koda, Teruyuki Ishikura, Yasuko Sugiyama, Keigo Kihara, Minami Kanakura, Tsuneo Nakajima, Shuko Takeda, Masanori P. Takahashi, Toshihide Yamashita, Tatsusada Okuno, Hideki Mochizuki

Sci Adv. 2023 Nov 24; 9(47): eadg3193. Published online 2023 Nov 22. doi: 10.1126/sciadv.adg3193

PMCID:: PMC10665002

Abstract Article PDF–1.7M

Select item 95874112.

RGMa promotes dedifferentiation of vascular smooth muscle cells into a macrophage-like phenotype in vivo and in vitro

Xiaofan Yuan, Hongmei Xiao, Qingzhe Hu, Guanru Shen, Xinyue Qin

J Lipid Res. 2022 Oct; 63(10): 100276. Published online 2022 Sep 9. doi: 10.1016/j.jlr.2022.100276

Correction in:: J Lipid Res. 2023 Feb; 64(2): 100331.

PMCID:: PMC9587411

Abstract Article PDF–7.1M

Select item 88091203.

RGMa regulates CCL5 expression via the BMP receptor in experimental autoimmune encephalomyelitis mice and endothelial cells

Shi Tang, Bao Su, Tao Tao, Weiping Yan, Rongrong Zhang, Xinyue Qin, Jinzhou Feng

Mol Med Rep. 2022 Mar; 25(3): 85. Published online 2022 Jan 13. doi: 10.3892/mmr.2022.12601

PMCID:: PMC8809120

Abstract Article PDF–2.2M

Select item 80630884.

Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling

Ross A. Robinson, Samuel C. Griffiths, Lieke L. van de Haar, Tomas Malinauskas, Eljo Y. van Battum, Pavol Zelina, Rebekka A. Schwab, Dimple Karia, Lina Malinauskaite, Sara Brignani, Marleen H. van den Munkhof, Özge Düdükcü, Anna A. De Ruiter, Dianne M.A. Van den Heuvel, Benjamin Bishop, Jonathan Elegheert, A. Radu Aricescu, R. Jeroen Pasterkamp, Christian Siebold

Cell. 2021 Apr 15; 184(8): 2103–2120.e31. doi: 10.1016/j.cell.2021.02.045

PMCID:: PMC8063088

Abstract Article

Select item 71603745.

Repulsive Guidance Molecule A Suppresses Adult Neurogenesis

Toke Jost Isaksen, Yuki Fujita, Toshihide Yamashita

Stem Cell Reports. 2020 Apr 14; 14(4): 677–691. Published online 2020 Apr 2. doi: 10.1016/j.stemcr.2020.03.003

PMCID:: PMC7160374

Abstract Article PDF–4.4M

Select item 67544176.

Effect of expression alteration in flanking genes on phenotypes of St8sia2-deficient mice

Keisuke Ikegami, Kazumasa Saigoh, Atsuko Fujioka, Mamoru Nagano, Ken Kitajima, Chihiro Sato, Satoru Masubuchi, Susumu Kusunoki, Yasufumi Shigeyoshi

Sci Rep. 2019; 9: 13634. Published online 2019 Sep 20. doi: 10.1038/s41598-019-50006-5

PMCID:: PMC6754417

Abstract Article PDF–4.4M

Select item 67303857.

DRAGON: A Member of the Repulsive Guidance Molecule-Related Family of Neuronal- and Muscle-Expressed Membrane Proteins Is Regulated by DRG11 and Has Neuronal Adhesive Properties

Tarek A. Samad, Ashok Srinivasan, Laurie A. Karchewski, Sung-Jin Jeong, Jason A. Campagna, Ru-Rong Ji, David A. Fabrizio, Ying Zhang, Herbert Y. Lin, Esther Bell, Clifford J. Woolf

J Neurosci. 2004 Feb 25; 24(8): 2027–2036. doi: 10.1523/JNEUROSCI.4115-03.2004

PMCID:: PMC6730385

Abstract Article PDF–873K

Select item 67298178.

Repulsive Guidance Molecule (RGM) Gene Function Is Required for Neural Tube Closure But Not Retinal Topography in the Mouse Visual System

Vera Niederkofler, Rishard Salie, Markus Sigrist, Silvia Arber

J Neurosci. 2004 Jan 28; 24(4): 808–818. doi: 10.1523/JNEUROSCI.4610-03.2004

PMCID:: PMC6729817

Abstract Article PDF–1.4M

Select item 67293539.

The Repulsive Guidance Molecule RGMa Is Involved in the Formation of Afferent Connections in the Dentate Gyrus

Henriette Brinks, Sabine Conrad, Johannes Vogt, Judit Oldekamp, Ana Sierra, Lutz Deitinghoff, Ingo Bechmann, Gonzalo Alvarez-Bolado, Bernd Heimrich, Philippe P. Monnier, Bernhard K. Mueller, Thomas Skutella

J Neurosci. 2004 Apr 14; 24(15): 3862–3869. doi: 10.1523/JNEUROSCI.5296-03.2004

PMCID:: PMC6729353

Abstract Article PDF–1.0M

Select item 636741310.

Sympathetic nervous system controls resolution of inflammation via regulation of repulsive guidance molecule A

Andreas Körner, Martin Schlegel, Torsten Kaussen, Verena Gudernatsch, Georg Hansmann, Timo Schumacher, Martin Giera, Valbona Mirakaj

Nat Commun. 2019; 10: 633. Published online 2019 Feb 7. doi: 10.1038/s41467-019-08328-5

PMCID:: PMC6367413

Abstract Article PDF–1.7M

Select item 619304411.

Inhibiting repulsive guidance molecule-a suppresses secondary progression in mouse models of multiple sclerosis

Shogo Tanabe, Yuki Fujita, Kaori Ikuma, Toshihide Yamashita

Cell Death Dis. 2018 Nov; 9(11): 1061. Published online 2018 Oct 17. doi: 10.1038/s41419-018-1118-4

PMCID:: PMC6193044

Abstract Article PDF–3.0M

Select item 604118012.

Genome-wide association study identifies a regulatory variant of RGMA associated with opioid dependence in European Americans

Zhongshan Cheng, Hang Zhou, Richard Sherva, Lindsay Farrer, Henry R. Kranzler, Joel Gelernter

Biol Psychiatry. Author manuscript; available in PMC 2019 Nov 15.

Published in final edited form as: Biol Psychiatry. 2018 Nov 15; 84(10): 762–770. Published online 2018 Jan 11. doi: 10.1016/j.biopsych.2017.12.016

PMCID:: PMC6041180

Abstract Article PDF–549K

Select item 554037613.

Inhibition of Repulsive Guidance Molecule, RGMa, Increases Afferent Synapse Formation with Auditory Hair Cells

Aurore Brugeaud, Mingjie Tong, Li Luo, Albert S.B. Edge

Dev Neurobiol. Author manuscript; available in PMC 2017 Aug 2.

Published in final edited form as: Dev Neurobiol. 2014 Apr; 74(4): 457–466. Published online 2013 Nov 20. doi: 10.1002/dneu.22136

PMCID:: PMC5540376

Abstract Article PDF–1.6M

Select item 484486314.

Transcriptome of the inner circular smooth muscle of the developing mouse intestine: evidence for regulation of visceral smooth muscle genes by the Hedgehog target gene, cJun

Katherine Gurdziel, Kyle R. Vogt, Katherine D. Walton, Gary K. Schneider, Deborah L. Gumucio

Dev Dyn. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Dev Dyn. 2016 May; 245(5): 614–626. Published online 2016 Mar 17. doi: 10.1002/dvdy.24399

PMCID:: PMC4844863

Abstract Article PDF–2.1M

Select item 476456515.

Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons

Sebastian Poliak, Daniel Morales, Louis-Philippe Croteau, Dayana Krawchuk, Elena Palmesino, Susan Morton, Jean-François Cloutier, Frederic Charron, Matthew B Dalva, Susan L Ackerman, Tzu-Jen Kao, Artur Kania

eLife. 2015; 4: e10841. Published online 2015 Dec 3. doi: 10.7554/eLife.10841

PMCID:: PMC4764565

Abstract Article PDF–5.0M

Select item 466194416.

Collaborative cross mice in a genetic association study reveal new candidate genes for bone microarchitecture

Roei Levy, Richard F. Mott, Fuad A. Iraqi, Yankel Gabet

BMC Genomics. 2015; 16: 1013. Published online 2015 Nov 26. doi: 10.1186/s12864-015-2213-x

PMCID:: PMC4661944

Abstract Article PDF–1.6M

Select item 384242417.

RGMa Regulates Cortical Interneuron Migration and Differentiation

Conor O'Leary, Stacey J. Cole, Michael Langford, Jayani Hewage, Amanda White, Helen M. Cooper

PLoS One. 2013; 8(11): e81711. Published online 2013 Nov 27. doi: 10.1371/journal.pone.0081711

PMCID:: PMC3842424

Abstract Article PDF–957K

Select item 367058518.

Dragon (RGMb) inhibits interleukin (IL)-6 expression in macrophages

Yin Xia, Virna Cortez-Retamozo, Vera Niederkofler, Rishard Salie, Shanzhuo Chen, Tarek Samad, Charles C. Hong, Silvia Arber, Jatin M. Vyas, Ralph Weissleder, Mikael J. Pittet, Herbert Y. Lin

J Immunol. Author manuscript; available in PMC 2013 Jun 3.

Published in final edited form as: J Immunol. 2011 Feb 1; 186(3): 1369–1376. Published online 2010 Dec 27. doi: 10.4049/jimmunol.1002047