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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 101513592.

Adenylyl cyclase 6 plays a minor role in the mouse inner ear and retina

Pranav Dinesh Mathur, Junhuang Zou, Grace Neiswanger, Daniel Zhu, Yong Wang, Ali A. Almishaal, Deepti Vashist, H. Kirk Hammond, Albert H. Park, Jun Yang

Sci Rep. 2023; 13: 7075. Published online 2023 May 1. doi: 10.1038/s41598-023-34361-y

PMCID:: PMC10151359

Abstract Article PDF–6.2M

Select item 90427083.

Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling

Bandarigoda Nipunika Somatilaka, Sun-Hee Hwang, Vivek Reddy Palicharla, Kevin Andrew White, Hemant Badgandi, John Michael Shelton, Saikat Mukhopadhyay

Dev Cell. Author manuscript; available in PMC 2022 Apr 27.

Published in final edited form as: Dev Cell. 2020 Sep 28; 54(6): 710–726.e8. Published online 2020 Jul 22. doi: 10.1016/j.devcel.2020.06.034

PMCID:: PMC9042708

Abstract Article PDF–3.9M

Select item 75732754.

AC6 regulates the microtubule-depolymerizing kinesin KIF19A to control ciliary length in mammals

Kavisha Arora, John R. Lund, Nevin A. Naren, Basilia Zingarelli, Anjaparavanda P. Naren

J Biol Chem. 2020 Oct 16; 295(42): 14250–14259. Published online 2020 Jul 18. doi: 10.1074/jbc.RA120.013703

PMCID:: PMC7573275

Abstract Article PDF–2.4M

Select item 69414995.

Adenylyl Cyclase 6 Expression Is Essential for Cholera Toxin–Induced Diarrhea

Robert A Fenton, Sathish K Murali, Izumi Kaji, Yasutada Akiba, Jonathan D Kaunitz, Tina B Kristensen, Søren B Poulsen, Jessica A Dominguez Rieg, Timo Rieg

J Infect Dis. 2019 Dec 1; 220(11): 1719–1728. Published online 2019 Jan 8. doi: 10.1093/infdis/jiz013

PMCID:: PMC6941499

Abstract Article PDF–5.4M

Select item 69201946.

Purβ promotes hepatic glucose production by increasing Adcy6 transcription

Linna Jia, Yunfeng Jiang, Xinzhi Li, Zheng Chen

Mol Metab. 2020 Jan; 31: 85–97. Published online 2019 Nov 16. doi: 10.1016/j.molmet.2019.11.008

PMCID:: PMC6920194

Abstract Article PDF–2.9M

Select item 66724407.

Molecular Characterization of the Ankle-Link Complex in Cochlear Hair Cells and Its Role in the Hair Bundle Functioning

Nicolas Michalski, Vincent Michel, Amel Bahloul, Gaëlle Lefèvre, Jérémie Barral, Hideshi Yagi, Sébastien Chardenoux, Dominique Weil, Pascal Martin, Jean-Pierre Hardelin, Makoto Sato, Christine Petit

J Neurosci. 2007 Jun 13; 27(24): 6478–6488. doi: 10.1523/JNEUROSCI.0342-07.2007

PMCID:: PMC6672440

Abstract Article PDF–1.0M

Select item 66686798.

Adenylyl cyclase 5–generated cAMP controls cerebral vascular reactivity during diabetic hyperglycemia

Arsalan U. Syed, Gopireddy R. Reddy, Debapriya Ghosh, Maria Paz Prada, Matthew A. Nystoriak, Stefano Morotti, Eleonora Grandi, Padmini Sirish, Nipavan Chiamvimonvat, Johannes W. Hell, Luis F. Santana, Yang K. Xiang, Madeline Nieves-Cintrón, Manuel F. Navedo

J Clin Invest. 2019 Aug 1; 129(8): 3140–3152. Published online 2019 Jul 2. doi: 10.1172/JCI124705

PMCID:: PMC6668679

Abstract Article PDF–7.1M

Select item 65569819.

Constitutive inhibitory G protein activity upon adenylyl cyclase-dependent cardiac contractility is limited to adenylyl cyclase type 6

Caroline Bull Melsom, Marie-Victoire Cosson, Øivind Ørstavik, Ngai Chin Lai, H. Kirk Hammond, Jan-Bjørn Osnes, Tor Skomedal, Viacheslav Nikolaev, Finn Olav Levy, Kurt Allen Krobert

PLoS One. 2019; 14(6): e0218110. Published online 2019 Jun 7. doi: 10.1371/journal.pone.0218110

PMCID:: PMC6556981

Abstract Article PDF–2.3M

Select item 651297010.

Adenylyl cyclase 6 is required for maintaining acid–base homeostasis

Søren Brandt Poulsen, Caralina Marin De Evsikova, Sathish Kumar Murali, Jeppe Praetorius, Yijuang Chern, Robert A. Fenton, Timo Rieg

Clin Sci (Lond) Author manuscript; available in PMC 2019 Aug 31.

Published in final edited form as: Clin Sci (Lond). 2018 Aug 31; 132(16): 1779–1796. Published online 2018 Aug 30. doi: 10.1042/CS20180060

PMCID:: PMC6512970

Abstract Article PDF–2.1M

Select item 610215211.

AC6 is the major adenylate cyclase forming a diarrheagenic protein complex with cystic fibrosis transmembrane conductance regulator in cholera

Andrew Thomas, Yashaswini Ramananda, KyuShik Mun, Anjaparavanda P. Naren, Kavisha Arora

J Biol Chem. 2018 Aug 17; 293(33): 12949–12959. Published online 2018 Jun 14. doi: 10.1074/jbc.RA118.003378

PMCID:: PMC6102152

Abstract Article PDF–2.2M

Select item 558404912.

The type VI adenylyl cyclase protects cardiomyocytes from β-adrenergic stress by a PKA/STAT3-dependent pathway

Yu-Shuo Wu, Chien-Chang Chen, Chen-Li Chien, Hsing-Lin Lai, Si-Tse Jiang, Yong-Cyuan Chen, Lin-Ping Lai, Wei-Fan Hsiao, Wen-Pin Chen, Yijuang Chern

J Biomed Sci. 2017; 24: 68. Published online 2017 Sep 4. doi: 10.1186/s12929-017-0367-3

PMCID:: PMC5584049

Abstract Article PDF–3.1M

Select item 554027513.

Cardiac-directed expression of a catalytically inactive adenylyl cyclase 6 protects the heart from sustained β-adrenergic stimulation

Mei Hua Gao, N. Chin Lai, Dimosthenis Giamouridis, Young Chul Kim, Tracy Guo, H. Kirk Hammond

PLoS One. 2017; 12(8): e0181282. Published online 2017 Aug 2. doi: 10.1371/journal.pone.0181282

PMCID:: PMC5540275

Abstract Article PDF–3.7M

Select item 541737714.

PPARγ-Dependent Regulation of Adenylate Cyclase 6 Amplifies the Stimulatory Effect of cAMP on Renin Gene Expression

Michael Desch, Thomas Schubert, Andrea Schreiber, Sandra Mayer, Björn Friedrich, Ferruh Artunc, Vladimir T. Todorov

Mol Endocrinol. November 1, 2010; 24(11): 2139–2151. doi: 10.1210/me.2010-0134

PMCID:: PMC5417377

Abstract Article

Select item 537407815.

Role of adenylyl cyclase 6 in the development of lithium-induced nephrogenic diabetes insipidus

Søren Brandt Poulsen, Tina Bøgelund Kristensen, Heddwen L. Brooks, Donald E. Kohan, Timo Rieg, Robert A. Fenton

JCI Insight. 2017 Apr 6; 2(7): e91042. Published online 2017 Apr 6. doi: 10.1172/jci.insight.91042

PMCID:: PMC5374078

Abstract Article PDF–1.8M

Select item 531649616.

Adenylyl Cyclase 5 links changes in calcium homeostasis to cAMP-dependent cyst growth in Polycystic Liver Disease

Carlo Spirli, Valeria Mariotti, Ambra Villani, Luca Fabris, Romina Fiorotto, Mario Strazzabosco

J Hepatol. Author manuscript; available in PMC 2018 Mar 1.

Published in final edited form as: J Hepatol. 2017 Mar; 66(3): 571–580. Published online 2016 Nov 5. doi: 10.1016/j.jhep.2016.10.032

PMCID:: PMC5316496

Abstract Article PDF–2.0M

Select item 477376517.

Type VI adenylyl cyclase negatively regulates GluN2B-mediated LTD and spatial reversal learning

Ching-Pang Chang, Cheng-Ta Lee, Wen-Hsien Hou, Meng-Syuan Lin, Hsing-Lin Lai, Chen-Li Chien, Chen Chang, Pei-Lin Cheng, Cheng-Chang Lien, Yijuang Chern

Sci Rep. 2016; 6: 22529. Published online 2016 Mar 2. doi: 10.1038/srep22529

PMCID:: PMC4773765

Abstract Article PDF–2.2M

Select item 461808618.

The Interleukin-2-mTORc1 Axis Defines the Reciprocal Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells

John P. Ray, Matthew M. Staron, Justin A. Shyer, Ping-Chih Ho, Heather D. Marshall, Simon M. Gray, Brian J. Laidlaw, Koichi Araki, Rafi Ahmed, Susan M. Kaech, Joe Craft

Immunity. Author manuscript; available in PMC 2016 Oct 20.

Published in final edited form as: Immunity. 2015 Oct 20; 43(4): 690–702. Published online 2015 Sep 22. doi: 10.1016/j.immuni.2015.08.017

PMCID:: PMC4618086

Abstract Article PDF–2.2M

Select item 428097319.

The role of adenylyl cyclase isoform 6 in β-adrenoceptor signalling in murine airways

Mark A Birrell, Sara J Bonvini, Michael A Wortley, James Buckley, Liang Yew-Booth, Sarah A Maher, Nicole Dale, Eric D Dubuis, Maria G Belvisi

Br J Pharmacol. 2015 Jan; 172(1): 131–141. Published online 2014 Nov 24. doi: 10.1111/bph.12905

PMCID:: PMC4280973

Abstract Article PDF–1.1M

Select item 427973820.

Tolvaptan plus Pasireotide Shows Enhanced Efficacy in a PKD1 Model

Katharina Hopp, Cynthia J. Hommerding, Xiaofang Wang, Hong Ye, Peter C. Harris, Vicente E. Torres

J Am Soc Nephrol. 2015 Jan; 26(1): 39–47. Published online 2014 Jul 3. doi: 10.1681/ASN.2013121312

PMCID:: PMC4279738

Abstract Article

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