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Items: 18

1.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
2.
HITS-CLIP analysis of human ALKBH8 reveals interactions with fully processed substrate tRNAs and with specific noncoding RNAs
Ivana Cavallin, Marek Bartosovic, Tomas Skalicky, Praveenkumar Rengaraj, Martin Demko, Martina Christina Schmidt-Dengler, Aleksej Drino, Mark Helm, Stepanka Vanacova
RNA. 2022 Dec; 28(12): 1568–1581. doi: 10.1261/rna.079421.122
PMCID:
PMC9670814
AbstractArticlePDF–7.1M
3.
Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery
Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili
Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z
PMCID:
PMC9279285
AbstractArticlePDF–2.5M
4.
Human TRMT112-Methyltransferase Network Consists of Seven Partners Interacting with a Common Co-Factor
Baiba Brūmele, Margit Mutso, Lilian Telanne, Kadri Õunap, Karīna Spunde, Aare Abroi, Reet Kurg
Int J Mol Sci. 2021 Dec; 22(24): 13593. Published online 2021 Dec 18. doi: 10.3390/ijms222413593
PMCID:
PMC8708615
AbstractArticlePDF–2.7M
5.
Neurodevelopmental disorder in an Egyptian family with a biallelic ALKBH8 variant
Ahmed K. Saad, Dana Marafi, Tadahiro Mitani, Haowei Du, Karima Rafat, Jawid M. Fatih, Shalini N. Jhangiani, Zeynep Coban-Akdemir, Baylor-Hopkins Center for Mendelian Genomics, Richard A. Gibbs, Davut Pehlivan, Jill V. Hunter, Jennifer E. Posey, Maha S. Zaki, James R. Lupski
Am J Med Genet A. Author manuscript; available in PMC 2021 Sep 20.
Published in final edited form as: Am J Med Genet A. 2021 Apr; 185(4): 1288–1293. Published online 2021 Feb 5. doi: 10.1002/ajmg.a.62100
PMCID:
PMC8450764
AbstractArticlePDF–506K
6.
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
Michael Aregger, Keith A. Lawson, Maximillian Billmann, Michael Costanzo, Amy H. Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Usaj, Lucy Nedyalkova, Olga Sizova, Andrea Habsid, Judy Pawling, Zhen-Yuan Lin, Hala Abdouni, Cassandra J. Wong, Alexander Weiss, Patricia Mero, James W. Dennis, Anne-Claude Gingras, Chad L. Myers, Brenda J. Andrews, Charles Boone, Jason Moffat
Nat Metab. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: Nat Metab. 2020 Jun; 2(6): 499–513. Published online 2020 Jun 1. doi: 10.1038/s42255-020-0211-z
PMCID:
PMC7566881
AbstractArticlePDF–4.8M
7.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
8.
Loss of epitranscriptomic control of selenocysteine utilization engages senescence and mitochondrial reprogramming
May Y. Lee, Andrea Leonardi, Thomas J. Begley, J. Andrés Melendez
Redox Biol. 2020 Jan; 28: 101375. Published online 2019 Nov 11. doi: 10.1016/j.redox.2019.101375
PMCID:
PMC6904832
AbstractArticlePDF–1.8M
9.
Recessive Truncating Mutations in ALKBH8 Cause Intellectual Disability and Severe Impairment of Wobble Uridine Modification
Dorota Monies, Cathrine Broberg Vågbø, Mohammad Al-Owain, Suzan Alhomaidi, Fowzan S. Alkuraya
Am J Hum Genet. 2019 Jun 6; 104(6): 1202–1209. Published online 2019 May 9. doi: 10.1016/j.ajhg.2019.03.026
PMCID:
PMC6556876
AbstractArticlePDF–1.2M
10.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
11.
Dependence of Human Colorectal Cells Lacking the FBW7 Tumor Suppressor on the Spindle Assembly Checkpoint
Melanie L. Bailey, Tejomayee Singh, Patricia Mero, Jason Moffat, Philip Hieter
Genetics. 2015 Nov; 201(3): 885–895. Published online 2015 Sep 8. doi: 10.1534/genetics.115.180653
PMCID:
PMC4649658
AbstractArticlePDF–1.8M
12.
hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes
Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal
Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012
PMCID:
PMC4647941
AbstractArticle
13.
Shared genetic susceptibility to ischemic stroke and coronary artery disease – a genome-wide analysis of common variants
Martin Dichgans, Rainer Malik, Inke R. König, Jonathan Rosand, Robert Clarke, Solveig Gretarsdottir, Gudmar Thorleifsson, Braxton D. Mitchell, Themistocles L. Assimes, Christopher Levi, Christopher J. O′Donnell, Myriam Fornage, Unnur Thorsteinsdottir, Bruce M. Psaty, Christian Hengstenberg, Sudha Seshadri, Jeanette Erdmann, Joshua C. Bis, Annette Peters, Giorgio B. Boncoraglio, Winfried März, James F. Meschia, Sekar Kathiresan, M. Arfan Ikram, Ruth McPherson, Kari Stefansson, Cathie Sudlow, Muredach P. Reilly, John R. Thompson, Pankaj Sharma, Jemma C. Hopewell, John C. Chambers, Hugh Watkins, Peter M. Rothwell, Robert Roberts, the METASTROKE Consortium, the CARDIoGRAM consortium, the C4D consortium, the International Stroke Genetics Consortium, Hugh S. Markus, Nilesh J. Samani, Martin Farrall, Heribert Schunkert
Stroke. Author manuscript; available in PMC 2015 Jan 1.
Published in final edited form as: Stroke. 2014 Jan; 45(1): 24–36. Published online 2013 Nov 21. doi: 10.1161/STROKEAHA.113.002707
PMCID:
PMC4112102
AbstractArticlePDF–979K
14.
Crystal Structure and RNA Binding Properties of the RNA Recognition Motif (RRM) and AlkB Domains in Human AlkB Homolog 8 (ABH8), an Enzyme Catalyzing tRNA Hypermodification
Chiara Pastore, Irini Topalidou, Farhad Forouhar, Amy C. Yan, Matthew Levy, John F. Hunt
J Biol Chem. 2012 Jan 13; 287(3): 2130–2143. Published online 2011 Nov 7. doi: 10.1074/jbc.M111.286187
PMCID:
PMC3265892
AbstractArticlePDF–4.1M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
Human AlkB Homolog ABH8 Is a tRNA Methyltransferase Required for Wobble Uridine Modification and DNA Damage Survival
Dragony Fu, Jennifer A. N. Brophy, Clement T. Y. Chan, Kyle A. Atmore, Ulrike Begley, Richard S. Paules, Peter C. Dedon, Thomas J. Begley, Leona D. Samson
Mol Cell Biol. 2010 May; 30(10): 2449–2459. Published online 2010 Mar 22. doi: 10.1128/MCB.01604-09
PMCID:
PMC2863699
AbstractArticlePDF–2.0M
17.
Mammalian ALKBH8 Possesses tRNA Methyltransferase Activity Required for the Biogenesis of Multiple Wobble Uridine Modifications Implicated in Translational Decoding
Lene Songe-Møller, Erwin van den Born, Vibeke Leihne, Cathrine B. Vågbø, Terese Kristoffersen, Hans E. Krokan, Finn Kirpekar, Pål Ø. Falnes, Arne Klungland
Mol Cell Biol. 2010 Apr; 30(7): 1814–1827. Published online 2010 Feb 1. doi: 10.1128/MCB.01602-09
PMCID:
PMC2838068
AbstractArticlePDF–3.4M
18.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
Mammalian Gene Collection (MGC) Program Team
Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899
PMCID:
PMC139241
AbstractArticlePDF–118K

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