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Select item 114154911.

CYP1B1-RMDN2 Alzheimer’s disease endophenotype locus identified for cerebral tau PET

Kwangsik Nho, Shannon L. Risacher, Liana G. Apostolova, Paula J. Bice, Jared R. Brosch, Rachael Deardorff, Kelley Faber, Martin R. Farlow, Tatiana Foroud, Sujuan Gao, Thea Rosewood, Jun Pyo Kim, Kelly Nudelman, Meichen Yu, Paul Aisen, Reisa Sperling, Basavaraj Hooli, Sergey Shcherbinin, Diana Svaldi, Clifford R. Jack, Jr., William J. Jagust, Susan Landau, Aparna Vasanthakumar, Jeffrey F. Waring, Vincent Doré, Simon M. Laws, Colin L. Masters, Tenielle Porter, Christopher C. Rowe, Victor L. Villemagne, Logan Dumitrescu, Timothy J. Hohman, Julia B. Libby, Elizabeth Mormino, Rachel F. Buckley, Keith Johnson, Hyun-Sik Yang, Ronald C. Petersen, Vijay K. Ramanan, Nilüfer Ertekin-Taner, Prashanthi Vemuri, Ann D. Cohen, Kang-Hsien Fan, M. Ilyas Kamboh, Oscar L. Lopez, David A. Bennett, Muhammad Ali, Tammie Benzinger, Carlos Cruchaga, Diana Hobbs, Philip L. De Jager, Masashi Fujita, Vaishnavi Jadhav, Bruce T. Lamb, Andy P. Tsai, Isabel Castanho, Jonathan Mill, Michael W. Weiner, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI), the Department of Defense Alzheimer’s Disease Neuroimaging Initiative (DoD-ADNI), the Anti-Amyloid Treatment in Asymptomatic Alzheimer’s Study (A4 Study) and Longitudinal Evaluation of Amyloid Risk and Neurodegeneration (LEARN), the Australian Imaging, Biomarker & Lifestyle Study (AIBL), Andrew J. Saykin

Nat Commun. 2024; 15: 8251. Published online 2024 Sep 20. doi: 10.1038/s41467-024-52298-2

PMCID:: PMC11415491

Abstract Article PDF–4.7M

Select item 109078252.

CYP1B1 affects the integrity of the blood–brain barrier and oxidative stress in the striatum: An investigation of manganese‐induced neurotoxicity

Juan Wu, Yueran Li, Shuwei Tian, Shufang Na, Hongyan Wei, Yafei Wu, Yafei Yang, Zixia Shen, Jiayue Ding, Shenglan Bao, Siqi Liu, Lingyun Li, Rongling Feng, Yong Zhu, Chunyan He, Jiang Yue

CNS Neurosci Ther. 2024 Mar; 30(3): e14633. Published online 2024 Mar 1. doi: 10.1111/cns.14633

PMCID:: PMC10907825

Abstract Article PDF–12M

Select item 105129663.

Genotyping of the rs1800440 Polymorphism in CYP1B1 Gene and the rs9258883 Polymorphism in HLA-B Gene in a Spanish Cohort of 223 Patients with Frontal Fibrosing Alopecia

David SACEDA-CORRALO, Daniel ORTEGA-QUIJANO, Gloria MUÑOZ-MARTÍN, Óscar M. MORENO-ARRONES, Cristina PINDADO-ORTEGA, Tuntas RAYINDA, Ana MELIÁN-OLIVERA, Carlos AZCÁRRAGA-LLOBET, Patricia BURGOS-BLASCO, María Elena CASTAÑEDA-BERMÚDEZ, Francisco J. DEL CASTILLO, Sergio VAÑÓ-GALVÁN

Acta Derm Venereol. 2023; 103: 9604. Published online 2023 Sep 18. doi: 10.2340/actadv.v103.9604

PMCID:: PMC10512966

Abstract Article PDF–1.0M

Select item 104742884.

ALKBH5 facilitates CYP1B1 mRNA degradation via m6A demethylation to alleviate MSC senescence and osteoarthritis progression

Guiwen Ye, Jinteng Li, Wenhui Yu, Zhongyu Xie, Guan Zheng, Wenjie Liu, Shan Wang, Qian Cao, Jiajie Lin, Zepeng Su, Dateng Li, Yunshu Che, Shuai Fan, Peng Wang, Yanfeng Wu, Huiyong Shen

Exp Mol Med. 2023 Aug; 55(8): 1743–1756. Published online 2023 Aug 1. doi: 10.1038/s12276-023-01059-0

PMCID:: PMC10474288

Abstract Article PDF–6.7M

Select item 104133565.

Mitochondrial cytochrome P450 1B1 is involved in pregnenolone synthesis in human brain cells

Yiqi Christina Lin, Garett Cheung, Zeyu Zhang, Vassilios Papadopoulos

J Biol Chem. 2023 Aug; 299(8): 105035. Published online 2023 Jul 11. doi: 10.1016/j.jbc.2023.105035

PMCID:: PMC10413356

Abstract Article PDF–2.3M

Select item 103802386.

Hydration and Structural Adaptations of the Human CYP1A1, CYP1A2, and CYP1B1 Active Sites by Molecular Dynamics Simulations

Zbigniew Dutkiewicz, Renata Mikstacka

Int J Mol Sci. 2023 Jul; 24(14): 11481. Published online 2023 Jul 14. doi: 10.3390/ijms241411481

PMCID:: PMC10380238

Abstract Article PDF–5.3M

Select item 102968417.

Human Adult Renal Progenitor Cells Prevent Cisplatin-Nephrotoxicity by Inducing CYP1B1 Overexpression and miR-27b-3p Down-Regulation through Extracellular Vesicles

Rossana Franzin, Alessandra Stasi, Giuseppe De Palma, Angela Picerno, Claudia Curci, Serena Sebastiano, Monica Campioni, Antonella Cicirelli, Alessandro Rizzo, Vito Francesco Di Lorenzo, Paola Pontrelli, Giovanni Battista Pertosa, Giuseppe Castellano, Loreto Gesualdo, Fabio Sallustio

Cells. 2023 Jun; 12(12): 1655. Published online 2023 Jun 17. doi: 10.3390/cells12121655

PMCID:: PMC10296841

Abstract Article PDF–5.4M

Select item 94628108.

Mutation screening of the CYP1B1 gene reveals thirteen novel disease-causing variants in consanguineous Pakistani families causing primary congenital glaucoma

Raeesa Tehreem, Anam Arooj, Sorath Noorani Siddiqui, Shagufta Naz, Kiran Afshan, Sabika Firasat

PLoS One. 2022; 17(9): e0274335. Published online 2022 Sep 9. doi: 10.1371/journal.pone.0274335

PMCID:: PMC9462810

Abstract Article PDF–2.7M

Select item 92316239.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 892293610.

CYP1B1-catalyzed 4-OHE2 promotes the castration resistance of prostate cancer stem cells by estrogen receptor α-mediated IL6 activation

Qimei Lin, Jiasong Cao, Xiaoling Du, Kuo Yang, Xu Yang, Zhixian Liang, Jiandang Shi, Ju Zhang

Cell Commun Signal. 2022; 20: 31. Published online 2022 Mar 15. doi: 10.1186/s12964-021-00807-x

PMCID:: PMC8922936

Abstract Article PDF–15M

Select item 876450811.

Novel compound heterozygous mutations in CYP1B1 identified in a Chinese family with developmental glaucoma

Suping Cai, Daren Zhang, Xiaodong Jiao, Tingting Wang, Mengjie Fan, Yun Wang, James Fielding Hejtmancik, Xuyang Liu

Mol Med Rep. 2021 Nov; 24(5): 803. Published online 2021 Sep 15. doi: 10.3892/mmr.2021.12443

PMCID:: PMC8764508

Abstract Article PDF–1.1M

Select item 873371212.

CYP1B1-AS1 Is a Novel Biomarker in Glioblastoma by Comprehensive Analysis

Tao Ye, Lan-lan Li, Xue-mei Peng, Qin Li

Dis Markers. 2021; 2021: 8565943. Published online 2021 Dec 29. doi: 10.1155/2021/8565943

PMCID:: PMC8733712

Abstract Article PDF–1.7M

Select item 855961313.

Development of an in vitro model to screen CYP1B1-targeted anticancer prodrugs

Zhiying Wang, Yao Chen, Laura M. Drbohlav, Judy Qiju Wu, Michael Zhuo Wang

J Biomol Screen. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: J Biomol Screen. 2016 Dec; 21(10): 1090–1099. doi: 10.1177/1087057116675315

PMCID:: PMC8559613

Abstract Article PDF–1.1M

Select item 848707914.

Procaspase-1 patrolled to the nucleus of proatherogenic lipid LPC-activated human aortic endothelial cells induces ROS promoter CYP1B1 and strong inflammation

Yifan Lu, Gayani Nanayakkara, Yu Sun, Lu Liu, Keman Xu, Charles Drummer, IV, Ying Shao, Fatma Saaoud, Eric T. Choi, Xiaohua Jiang, Hong Wang, Xiaofeng Yang

Redox Biol. 2021 Nov; 47: 102142. Published online 2021 Sep 27. doi: 10.1016/j.redox.2021.102142

PMCID:: PMC8487079

Abstract Article PDF–9.2M

Select item 794690015.

Profiling of CYP4Z1 and CYP1B1 expression in bladder cancers

Yousef M. Al-saraireh, Fatemah O. F. O. Alshammari, Ahmed M. M. Youssef, Sameeh Al-Sarayreh, Ghadeer H. Almuhaisen, Nedal Alnawaiseh, Jehad M. Al Shuneigat, Hamzeh M. Alrawashdeh

Sci Rep. 2021; 11: 5581. Published online 2021 Mar 10. doi: 10.1038/s41598-021-85188-4

PMCID:: PMC7946900

Abstract Article PDF–1.6M

Select item 741471916.

Exome Sequencing in a Swiss Childhood Glaucoma Cohort Reveals CYP1B1 and FOXC1 Variants as Most Frequent Causes

Elena Lang, Samuel Koller, Luzy Bähr, Marc Töteberg-Harms, David Atac, Françoise Roulez, Angela Bahr, Katharina Steindl, Silke Feil, Wolfgang Berger, Christina Gerth-Kahlert

Transl Vis Sci Technol. 2020 Jun; 9(7): 47. Published online 2020 Jun 30. doi: 10.1167/tvst.9.7.47

PMCID:: PMC7414719

Abstract Article PDF–650K

Select item 732206717.

RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation

Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen

Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117

PMCID:: PMC7322067

Abstract Article PDF–2.7M

Select item 718616918.

Structure of an ancestral mammalian family 1B1 cytochrome P450 with increased thermostability

Aaron G. Bart, Kurt L. Harris, Elizabeth M. J. Gillam, Emily E. Scott

J Biol Chem. 2020 Apr 24; 295(17): 5640–5653. Published online 2020 Mar 10. doi: 10.1074/jbc.RA119.010727

PMCID:: PMC7186169

Abstract Article PDF–2.5M

Select item 698617819.

CYP1B1, VEGFA, BCL2, and CDKN1A Affect the Development of Chronic Obstructive Pulmonary Disease

Danlei Yang, Ying Yan, Fen Hu, Tao Wang

Int J Chron Obstruct Pulmon Dis. 2020; 15: 167–175. Published online 2020 Jan 23. doi: 10.2147/COPD.S220675

PMCID:: PMC6986178

Abstract Article PDF–1.8M

Select item 674682220.

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei

Giovanni Nassa, Giorgio Giurato, Annamaria Salvati, Valerio Gigantino, Giovanni Pecoraro, Jessica Lamberti, Francesca Rizzo, Tuula A. Nyman, Roberta Tarallo, Alessandro Weisz

Sci Data. 2019; 6: 173. Published online 2019 Sep 16. doi: 10.1038/s41597-019-0179-2

PMCID:: PMC6746822

Abstract Article PDF–2.0M

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