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Items: 1 to 20 of 50

1.
Adenovirus vector‐mediated upregulation of spermidine /spermine N1‐acetyltransferase impairs human gastric cancer growth in  vitro and in vivo
Bin Liu, Hui Sun, Wei Wang, Wei Li, Yun‐Fei Yan, Shi‐Min Chen, Ya‐Pei Yang, Chun‐Xiao Xu, Jia‐Xuan Xin, Xian‐Xi Liu
Cancer Sci. 2009 Nov; 100(11): 2126–2132. Published online 2009 Jul 21. doi: 10.1111/j.1349-7006.2009.01290.x
PMCID:
PMC11159126
AbstractArticlePDF–472K
2.
MNT inhibits lung adenocarcinoma ferroptosis and chemosensitivity by suppressing SAT1
Guangyin Zhao, Jiaqi Liang, Yuchen Zhang, Guangyao Shan, Yunyi Bian, Jie Gu, Cheng Zhan, Di Ge
Commun Biol. 2024; 7: 680. Published online 2024 Jun 3. doi: 10.1038/s42003-024-06373-5
PMCID:
PMC11148173
AbstractArticlePDF–2.9M
3.
Loss-of-function variants in SAT1 cause X-linked Childhood-onset Systemic Lupus Erythematosus
Lingxiao Xu, Jian Zhao, Qing Sun, Xue Xu, Lei Wang, Ting Liu, Yunjuan Wu, Jingfeng Zhu, Linyu Geng, Yun Deng, Alexander Awgulewitsch, Diane L. Kamen, Jim C. Oates, Prithvi Raj, Edward K. Wakeland, R. Hal Scofield, Joel M. Guthridge, Judith A. James, Bevra H Hahn, Deborah K. McCurdy, Fang Wang, Miaojia Zhang, Wenfeng Tan, Gary S. Gilkeson, Betty P. Tsao
Ann Rheum Dis. Author manuscript; available in PMC 2023 Dec 1.
Published in final edited form as: Ann Rheum Dis. 2022 Dec; 81(12): 1712–1721. Published online 2022 Aug 17. doi: 10.1136/ard-2022-222795
PMCID:
PMC10394691
AbstractArticlePDF–1.8M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Dengue virus targets RBM10 deregulating host cell splicing and innate immune response
Berta Pozzi, Laureano Bragado, Pablo Mammi, María Florencia Torti, Nicolás Gaioli, Leopoldo G Gebhard, Martín E García Solá, Rita Vaz-Drago, Néstor G Iglesias, Cybele C García, Andrea V Gamarnik, Anabella Srebrow
Nucleic Acids Res. 2020 Jul 9; 48(12): 6824–6838. Published online 2020 May 20. doi: 10.1093/nar/gkaa340
PMCID:
PMC7337517
AbstractArticlePDF–3.5M
6.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
7.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
8.
Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity
Jae Jin Kim, Seo Yun Lee, Fade Gong, Anna M. Battenhouse, Daniel R. Boutz, Aarti Bashyal, Samantha T. Refvik, Cheng-Ming Chiang, Blerta Xhemalce, Tanya T. Paull, Jennifer S. Brodbelt, Edward M. Marcotte, Kyle M. Miller
Genes Dev. 2019 Dec 1; 33(23-24): 1751–1774. doi: 10.1101/gad.331231.119
PMCID:
PMC6942044
AbstractArticlePDF–10M
9.
Spermidine/spermine N1-acetyltransferase 1 is a gene-specific transcriptional regulator that drives brain tumor aggressiveness
Vijay S. Thakur, Brittany Aguila, Adina Brett-Morris, Chad J. Creighton, Scott M. Welford
Oncogene. Author manuscript; available in PMC 2020 Feb 9.
Published in final edited form as: Oncogene. 2019 Oct; 38(41): 6794–6800. Published online 2019 Aug 9. doi: 10.1038/s41388-019-0917-0
PMCID:
PMC6786946
AbstractArticlePDF–2.4M
10.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
11.
Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance
Matthew F Pech, Linda E Fong, Jacqueline E Villalta, Leanne JG Chan, Samir Kharbanda, Jonathon J O'Brien, Fiona E McAllister, Ari J Firestone, Calvin H Jan, Jeffrey Settleman
eLife. 2019; 8: e47362. Published online 2019 Aug 27. doi: 10.7554/eLife.47362
PMCID:
PMC6713475
AbstractArticlePDF–4.6M
12.
An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders
Siwei Chen, Robert Fragoza, Lambertus Klei, Yuan Liu, Jiebiao Wang, Kathryn Roeder, Bernie Devlin, Haiyuan Yu
Nat Genet. Author manuscript; available in PMC 2019 Jul 1.
Published in final edited form as: Nat Genet. 2018 Jul; 50(7): 1032–1040. Published online 2018 Jun 11. doi: 10.1038/s41588-018-0130-z
PMCID:
PMC6314957
AbstractArticlePDF–1.3M
13.
A genome-wide CRISPR screen identifies genes critical for resistance to FLT3 inhibitor AC220
Panpan Hou, Chao Wu, Yuchen Wang, Rui Qi, Dheeraj Bhavanasi, Zhixiang Zuo, Cedric Dos Santos, Shuliang Chen, Yu Chen, Hong Zheng, Hong Wang, Alexander Perl, Deyin Guo, Jian Huang
Cancer Res. Author manuscript; available in PMC 2018 Aug 15.
Published in final edited form as: Cancer Res. 2017 Aug 15; 77(16): 4402–4413. Published online 2017 Jun 16. doi: 10.1158/0008-5472.CAN-16-1627
PMCID:
PMC5559306
AbstractArticlePDF–885K
14.
Spermidine/spermine N1-acetyltransferase regulates cell growth and metastasis via AKT/β-catenin signaling pathways in hepatocellular and colorectal carcinoma cells
Cong Wang, Ping Ruan, Ying Zhao, Xiaomin Li, Jun Wang, Xiaoxiao Wu, Tong Liu, Shasha Wang, Jiuzhou Hou, Wei Li, Qian Li, Jinghua Li, Fujun Dai, Dong Fang, Chaojie Wang, Songqiang Xie
Oncotarget. 2017 Jan 3; 8(1): 1092–1109. Published online 2016 Nov 25. doi: 10.18632/oncotarget.13582
PMCID:
PMC5352037
AbstractArticlePDF–16M
15.
Activation of SAT1 engages polyamine metabolism with p53-mediated ferroptotic responses
Yang Ou, Shang-Jui Wang, Dawei Li, Bo Chu, Wei Gu
Proc Natl Acad Sci U S A. 2016 Nov 1; 113(44): E6806–E6812. Published online 2016 Oct 3. doi: 10.1073/pnas.1607152113
PMCID:
PMC5098629
AbstractArticlePDF–1.3M
16.
Isoform-level brain expression profiling of the spermidine/spermine N1-Acetyltransferase1 (SAT1) gene in major depression and suicide
Spiro P. Pantazatos, Stuart J. Andrews, Jane Dunning-Broadbent, Jiuhong Pang, Yung-yu Huang, Victoria Arango, Peter L. Nagy, J. John Mann
Neurobiol Dis. Author manuscript; available in PMC 2016 Apr 18.
Published in final edited form as: Neurobiol Dis. 2015 Jul; 79: 123–134. Published online 2015 May 8. doi: 10.1016/j.nbd.2015.04.014
PMCID:
PMC4834874
AbstractArticlePDF–673K
17.
Depletion of the Polyamines Spermidine and Spermine by Overexpression of Spermidine/spermine N1-Acetyltransferase1 (SAT1) Leads to Mitochondria-Mediated Apoptosis in Mammalian Cells
Swati Mandal, Ajeet Mandal, Myung Hee Park
Biochem J. Author manuscript; available in PMC 2015 Aug 26.
Published in final edited form as: Biochem J. 2015 Jun 15; 468(3): 435–447. Published online 2015 Apr 7. doi: 10.1042/BJ20150168
PMCID:
PMC4550555
AbstractArticlePDF–1.0M
18.
Expression of Spermidine/Spermine N1-Acetyl Transferase (SSAT) in Human Prostate Tissues is Related to Prostate Cancer Progression and Metastasis
Wei Huang, Jens C Eickhoff, Farideh Mehraein Ghomi, Dawn R. Church, George Wilding, Hirak S. Basu
Prostate. Author manuscript; available in PMC 2016 Aug 1.
Published in final edited form as: Prostate. 2015 Aug; 75(11): 1150–1159. Published online 2015 Apr 20. doi: 10.1002/pros.22996
PMCID:
PMC4475436
AbstractArticlePDF–1.7M
19.
The polyamine catabolic enzymeSAT1 modulates tumorigenesis and radiation response in GBM
Adina Brett-Morris, Bradley M. Wright, Yuji Seo, Vinay Pasupuleti, Junran Zhang, Jun Lu, Raffaella Spina, Eli E. Bar, Maneesh Gujrati, Rebecca Schur, Zheng-Rong Lu, Scott M. Welford
Cancer Res. Author manuscript; available in PMC 2015 Dec 1.
Published in final edited form as: Cancer Res. 2014 Dec 1; 74(23): 6925–6934. Published online 2014 Oct 2. doi: 10.1158/0008-5472.CAN-14-1249
PMCID:
PMC4423404
AbstractArticlePDF–1.3M
20.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M

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