PMC Links for GEO Profiles (Select 88526074) - PMC

Yo Fujii, Masayoshi Yada, Masaaki Nishiyama, Takumi Kamura, Hidehisa Takahashi, Ryosuke Tsunematsu, Etsuo Susaki, Tadashi Nakagawa, Akinobu Matsumoto, Keiichi I. Nakayama

Cancer Sci. 2006 Aug; 97(8): 729–736. Published online 2006 Jul 4. doi: 10.1111/j.1349-7006.2006.00239.x

PMCID:: PMC11159495

Abstract Article PDF–359K

Select item 110720946.

AUF1 protects against ferroptosis to alleviate sepsis-induced acute lung injury by regulating NRF2 and ATF3

Yichun Wang, Diyu Chen, Han Xie, Mingwang Jia, Xiaofang Sun, Fang Peng, Feifei Guo, Daolin Tang

Cell Mol Life Sci. 2022 May; 79(5): 228. Published online 2022 Apr 7. doi: 10.1007/s00018-022-04248-8

PMCID:: PMC11072094

Abstract Article PDF–11M

Select item 110720127.

E3-ubiquitin ligase, FBXW7 regulates mitotic progression by targeting BubR1 for ubiquitin-mediated degradation

Vishnu M. Nair, Amit Santhu Sabu, Ahmed Hussain, Delvin P. Kombarakkaran, R. Bhagya Lakshmi, Tapas K. Manna

Cell Mol Life Sci. 2023 Dec; 80(12): 374. Published online 2023 Nov 26. doi: 10.1007/s00018-023-05019-9

PMCID:: PMC11072012

Abstract Article PDF–11M

Select item 110267298.

The SCF-FBW7β E3 ligase mediates ubiquitination and degradation of the serine/threonine protein kinase PINK1

Seo Jeong Jeon, Kwang Chul Chung

J Biol Chem. 2024 Apr; 300(4): 107198. Published online 2024 Mar 18. doi: 10.1016/j.jbc.2024.107198

PMCID:: PMC11026729

Abstract Article PDF–4.8M

Select item 109629679.

Epidermal growth factor receptor (EGFR) is a target of the tumor-suppressor E3 ligase FBXW7

Matteo Boretto, Maarten H. Geurts, Shashank Gandhi, Ziliang Ma, Nadzeya Staliarova, Martina Celotti, Sangho Lim, Gui-Wei He, Rosemary Millen, Else Driehuis, Harry Begthel, Lidwien Smabers, Jeanine Roodhart, Johan van Es, Wei Wu, Hans Clevers

Proc Natl Acad Sci U S A. 2024 Mar 19; 121(12): e2309902121. Published online 2024 Mar 14. doi: 10.1073/pnas.2309902121

PMCID:: PMC10962967

Abstract Article PDF–5.5M

Select item 1092008610.

ASPM stabilizes the NOTCH intracellular domain 1 and promotes oncogenesis by blocking FBXW7 binding in hepatocellular carcinoma cells

Tze‐Sian Chan, Li‐Hsin Cheng, Chung‐Chi Hsu, Pei‐Ming Yang, Tai‐Yan Liao, Hsiao‐Yen Hsieh, Pei‐Chun Lin, Wei‐Chun HuangFu, Chih‐Pin Chuu, Kelvin K. Tsai

Mol Oncol. 2024 Mar; 18(3): 562–579. Published online 2024 Jan 26. doi: 10.1002/1878-0261.13589

PMCID:: PMC10920086

Abstract Article PDF–6.1M

Select item 1085081811.

Cancer‐associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7

Joseph S. Baxter, Rachel Brough, Dragomir B. Krastev, Feifei Song, Sandhya Sridhar, Aditi Gulati, John Alexander, Theodoros I. Roumeliotis, Zuza Kozik, Jyoti S. Choudhary, Syed Haider, Stephen J. Pettitt, Andrew N. J. Tutt, Christopher J. Lord

Mol Oncol. 2024 Feb; 18(2): 369–385. Published online 2023 Oct 22. doi: 10.1002/1878-0261.13537

PMCID:: PMC10850818

Abstract Article PDF–2.7M

Select item 1080976812.

Fbxw7 suppresses carcinogenesis and stemness in triple-negative breast cancer through CHD4 degradation and Wnt/β-catenin pathway inhibition

Guodong Xiao, Weiping Lu, Jing Yuan, Zuyue Liu, Peili Wang, Huijie Fan

J Transl Med. 2024; 22: 99. Published online 2024 Jan 24. doi: 10.1186/s12967-024-04897-2

PMCID:: PMC10809768

Abstract Article PDF–6.6M

Select item 1073438913.

FBXW7-loss Sensitizes Cells to ATR Inhibition Through Induced Mitotic Catastrophe

Siobhan O'Brien, Tajinder Ubhi, Lucie Wolf, Krishna Gandhi, Sichun Lin, Naz Chaudary, Neesha C. Dhani, Michael Milosevic, Grant W. Brown, Stephane Angers

Cancer Res Commun. 2023 Dec; 3(12): 2596–2607. Published online 2023 Dec 21. doi: 10.1158/2767-9764.CRC-23-0306

PMCID:: PMC10734389

Abstract Article PDF–11M

Select item 1050940614.

FBXW7 Enhances Cisplatin-Induced Apoptosis in Oral Cancer Cell Lines

Qi Yang, Yang Sun, Bo Qiu, Huanhuan Zhao

Int Dent J. 2023 Oct; 73(5): 620–627. Published online 2022 Dec 5. doi: 10.1016/j.identj.2022.11.008

PMCID:: PMC10509406

Abstract Article PDF–1.4M

Select item 1049589915.

Epigenetic Status of FBXW7 Gene and Its Role in Ovarian Cancer Pathogenesis

Meerah Al Hinai, Shika Hanif Malgundkar, Ishita Gupta, Ritu Lakhtakia, Moza Al Kalbani, Ikram Burney, Mansour Al Moundhri, Aikou Okamoto, Yahya Tamimi

Asian Pac J Cancer Prev. 2023; 24(5): 1583–1590. doi: 10.31557/APJCP.2023.24.5.1583

PMCID:: PMC10495899

Abstract Article PDF–1.2M

Select item 1048680316.

The Highs and Lows of FBXW7: New Insights into Substrate Affinity in Disease and Development

Claire C. de la Cova

Cells. 2023 Sep; 12(17): 2141. Published online 2023 Aug 24. doi: 10.3390/cells12172141

PMCID:: PMC10486803

Abstract Article PDF–1.7M

Select item 1047466617.

FBXW7 in breast cancer: mechanism of action and therapeutic potential

Siyu Chen, Ping Leng, Jinlin Guo, Hao Zhou

J Exp Clin Cancer Res. 2023; 42: 226. Published online 2023 Sep 2. doi: 10.1186/s13046-023-02767-1

PMCID:: PMC10474666

Abstract Article PDF–2.6M

Select item 1035260518.

CCNB1IP1 prevents ubiquitination‐mediated destabilization of MYCN and potentiates tumourigenesis of MYCN‐amplificated neuroblastoma

Yang Zhou, Hui Yan, Qiang Zhou, Penggao Wang, Fang Yang, Ziqiao Yuan, Qianming Du, Bo Zhai

Clin Transl Med. 2023 Jul; 13(7): e1328. Published online 2023 Jul 17. doi: 10.1002/ctm2.1328

PMCID:: PMC10352605

Abstract Article PDF–6.2M

Select item 1031451919.

Enhancement of TKI sensitivity in lung adenocarcinoma through m6A-dependent translational repression of Wnt signaling by circ-FBXW7

Kai Li, Zi-Yang Peng, Rui Wang, Xiang Li, Ning Du, Da-Peng Liu, Jia Zhang, Yun-Feng Zhang, Lei Ma, Ye Sun, Shou-Ching Tang, Hong Ren, Yi-Ping Yang, Xin Sun

Mol Cancer. 2023; 22: 103. Published online 2023 Jul 1. doi: 10.1186/s12943-023-01811-0

PMCID:: PMC10314519

Abstract Article PDF–8.4M

Select item 1028094020.

CircNFATC3 promotes the proliferation of gastric cancer through binding to IGF2BP3 and restricting its ubiquitination to enhance CCND1 mRNA stability

Feifei Yang, Qiang Ma, Bo Huang, Xiaolin Wang, Xiaojuan Pan, Ting Yu, Lingyu Ran, Shan Jiang, Haiping Li, Ye Chen, Yuying Liu, Ce Liang, Junwu Ren, Yuying Zhang, Shimin Wang, Wei Li, Bin Xiao

J Transl Med. 2023; 21: 402. Published online 2023 Jun 20. doi: 10.1186/s12967-023-04235-y