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Select item 100835841.

Structural insights into constitutive activity of 5-HT₆ receptor

Licong He, Qiaoyu Zhao, Jianzhong Qi, Yifan Wang, Wenyu Han, Zhangcheng Chen, Yao Cong, Sheng Wang

Proc Natl Acad Sci U S A. 2023 Apr 4; 120(14): e2209917120. Published online 2023 Mar 29. doi: 10.1073/pnas.2209917120

PMCID:: PMC10083584

Abstract Article PDF–2.3M

Select item 89609642.

Systematic Analysis of Neurotransmitter Receptors in Human Breast Cancer Reveals a Strong Association With Outcome and Uncovers HTR6 as a Survival-Associated Gene Potentially Regulating the Immune Microenvironment

Wei Zhang, Lintai Li, Jianxuan Li, Haiyan Yu, Fengping Zheng, Bin Yan, Wanxia Cai, Yumei Chen, Lianghong Yin, Donge Tang, Yong Xu, Yong Dai

Front Immunol. 2022; 13: 756928. Published online 2022 Mar 10. doi: 10.3389/fimmu.2022.756928

PMCID:: PMC8960964

Abstract Article PDF–18M

Select item 88970223.

Histone deacetylase inhibitors inhibit cervical cancer growth through Parkin acetylation-mediated mitophagy

Xin Sun, Yuhan Shu, Guiqin Ye, Caixia Wu, Mengting Xu, Ruilan Gao, Dongsheng Huang, Jianbin Zhang

Acta Pharm Sin B. 2022 Feb; 12(2): 838–852. Published online 2021 Jul 21. doi: 10.1016/j.apsb.2021.07.003

PMCID:: PMC8897022

Abstract Article PDF–3.0M

Select item 78159444.

Constitutive Activity of Serotonin Receptor 6 Regulates Human Cerebral Organoids Formation and Depression-like Behaviors

Qinying Wang, Xiaoxu Dong, Tingting Hu, Chao Qu, Jing Lu, Yue Zhou, Jinsong Li, Gang Pei

Stem Cell Reports. 2021 Jan 12; 16(1): 75–88. Published online 2020 Dec 23. doi: 10.1016/j.stemcr.2020.11.015

PMCID:: PMC7815944

Abstract Article PDF–3.8M

Select item 77727735.

HTR6 and SSTR3 ciliary targeting relies on both IC3 loops and C-terminal tails

Pablo Barbeito, Yuki Tachibana, Raquel Martin-Morales, Paula Moreno, Kirk Mykytyn, Tetsuo Kobayashi, Francesc R Garcia-Gonzalo

Life Sci Alliance. 2021 Mar; 4(3): e202000746. Published online 2020 Dec 28. doi: 10.26508/lsa.202000746

PMCID:: PMC7772773

Abstract Article PDF–5.6M

Select item 70315426.

Correlation of 5‐HTR6 gene polymorphism with vestibular migraine

Xia Wu, Feng Qiu, Zhiwei Wang, Bing Liu, Xiaokun Qi

J Clin Lab Anal. 2020 Feb; 34(2): e23042. Published online 2019 Oct 6. doi: 10.1002/jcla.23042

Correction in:: J Clin Lab Anal. 2020 Jun; 34(6): 10.1002/jcla.23432.

PMCID:: PMC7031542

Abstract Article PDF–275K

Select item 64015467.

Physical and Functional Interaction between 5-HT₆ Receptor and Nova-1

Soon-Hee Kim, Misun Seo, Hongik Hwang, Dong-Min Moon, Gi Hoon Son, Kyungjin Kim, Hyewhon Rhim

Exp Neurobiol. 2019 Feb; 28(1): 17–29. Published online 2019 Jan 21. doi: 10.5607/en.2019.28.1.17

PMCID:: PMC6401546

Abstract Article PDF–2.8M

Select item 53717308.

Systematic protein–protein interaction mapping for clinically relevant human GPCRs

Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar

Mol Syst Biol. 2017 Mar; 13(3): 918. Published online 2017 Mar 15. doi: 10.15252/msb.20167430

PMCID:: PMC5371730

Abstract Article PDF–4.1M

Select item 50870179.

Physical interaction between neurofibromin and serotonin 5-HT₆ receptor promotes receptor constitutive activity

Wissem Deraredj Nadim, Séverine Chaumont-Dubel, Fahima Madouri, Laetitia Cobret, Marie-Ludivine De Tauzia, Pawel Zajdel, Hélène Bénédetti, Philippe Marin, Séverine Morisset-Lopez

Proc Natl Acad Sci U S A. 2016 Oct 25; 113(43): 12310–12315. Published online 2016 Oct 10. doi: 10.1073/pnas.1600914113

PMCID:: PMC5087017

Abstract Article PDF–1.0M

Select item 469494710.

Serotonin 6 receptor controls alzheimer’s disease and depression

Hyung-Mun Yun, Kyung-Ran Park, Eun-Cheol Kim, Sanghyeon Kim, Jin Tae Hong

Oncotarget. 2015 Sep 29; 6(29): 26716–26728. Published online 2015 Sep 22. doi: 10.18632/oncotarget.5777

PMCID:: PMC4694947

Abstract Article PDF–5.4M

Select item 394886011.

Direct Interaction and Functional Coupling between Human 5-HT₆ Receptor and the Light Chain 1 Subunit of the Microtubule-Associated Protein 1B (MAP1B-LC1)

Soon-Hee Kim, Dong Hyuk Kim, Kang Ho Lee, Sun-Kyoung Im, Eun-Mi Hur, Kwang Chul Chung, Hyewhon Rhim

PLoS One. 2014; 9(3): e91402. Published online 2014 Mar 10. doi: 10.1371/journal.pone.0091402

PMCID:: PMC3948860

Abstract Article PDF–1.3M

Select item 349183512.

5-HT₆ receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia

Julie Meffre, Séverine Chaumont-Dubel, Clotilde Mannoury la Cour, Florence Loiseau, David J G Watson, Anne Dekeyne, Martial Séveno, Jean-Michel Rivet, Florence Gaven, Paul Déléris, Denis Hervé, Kevin C F Fone, Joël Bockaert, Mark J Millan, Philippe Marin

EMBO Mol Med. 2012 Oct; 4(10): 1043–1056. Published online 2012 Oct 2. doi: 10.1002/emmm.201201410

PMCID:: PMC3491835

Abstract Article PDF–1.1M

Select item 345218913.

Lack of association between five serotonin metabolism-related genes and medication overuse headache

Sabina Cevoli, Nadia Marzocchi, Sabina Capellari, Chiara Scapoli, Giulia Pierangeli, Daniela Grimaldi, Federica Naldi, L. Alberto Pini, Pasquale Montagna, Pietro Cortelli

J Headache Pain. 2010 Feb; 11(1): 53–58. Published online 2009 Nov 21. doi: 10.1007/s10194-009-0168-5

PMCID:: PMC3452189

Summary PDF–180K

Select item 330948614.

Excess of serotonin affects neocortical pyramidal neuron migration

O Riccio, M Jacobshagen, B Golding, L Vutskits, D Jabaudon, J P Hornung, A G Dayer

Transl Psychiatry. 2011 Oct; 1(10): e47. Published online 2011 Oct 11. doi: 10.1038/tp.2011.49

Correction in:: Transl Psychiatry. 2012 Mar; 2(3): e95.

PMCID:: PMC3309486

Abstract Article PDF–751K

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 314651316.

Serotonin Receptor Expression in Human Prefrontal Cortex: Balancing Excitation and Inhibition across Postnatal Development

Evelyn K. Lambe, Stu G. Fillman, Maree J. Webster, Cynthia Shannon Weickert

PLoS One. 2011; 6(7): e22799. Published online 2011 Jul 29. doi: 10.1371/journal.pone.0022799

PMCID:: PMC3146513

Abstract Article PDF–416K

Select item 298649917.

Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis

Anna C Need, Richard SE Keefe, Dongliang Ge, Iris Grossman, Sam Dickson, Joseph P McEvoy, David B Goldstein

Eur J Hum Genet. 2009 Jul; 17(7): 946–957. Published online 2009 Jan 21. doi: 10.1038/ejhg.2008.264

PMCID:: PMC2986499

Abstract Article PDF–172K

Select item 296315418.

Association Study of 182 Candidate Genes in Anorexia Nervosa

Andrea Poyastro Pinheiro, Cynthia M. Bulik, Laura M. Thornton, Patrick F. Sullivan, Tammy L. Root, Cinnamon S. Bloss, Wade H. Berrettini, Nicholas J. Schork, Walter H. Kaye, Andrew W. Bergen, Pierre Magistretti, Harry Brandt, Steve Crawford, Scott Crow, Manfred M. Fichter, David Goldman, Katherine A. Halmi, Craig Johnson, Allan S. Kaplan, Pamela K. Keel, Kelly L. Klump, Maria La Via, James E. Mitchell, Michael Strober, Alessandro Rotondo, Janet Treasure, D. Blake Woodside

Am J Med Genet B Neuropsychiatr Genet. Author manuscript; available in PMC 2010 Oct 25.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2010 Jul; 153B(5): 1070–1080. doi: 10.1002/ajmg.b.31082

PMCID:: PMC2963154

Abstract Article PDF–315K

Select item 292192019.

Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?

Gualberto Ruaño, Paul D Thompson, John P Kane, Clive R Pullinger, Andreas Windemuth, Richard L Seip, Mohan Kocherla, Theodore R Holford, Alan HB Wu

Pharmacogenomics. Author manuscript; available in PMC 2011 May 1.

Published in final edited form as: Pharmacogenomics. 2010 Jul; 11(7): 959–971. doi: 10.2217/pgs.10.58

PMCID:: PMC2921920

Abstract Article PDF–1.4M

Select item 284316520.

Physical Interaction of Jab1 with Human Serotonin 6 G-protein-coupled Receptor and Their Possible Roles in Cell Survival

Hyung-Mun Yun, Ja-Hyun Baik, Insug Kang, Changbae Jin, Hyewhon Rhim

J Biol Chem. 2010 Mar 26; 285(13): 10016–10029. Published online 2010 Jan 21. doi: 10.1074/jbc.M109.068759

PMCID:: PMC2843165

Abstract Article PDF–3.3M

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