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Select item 100355241.

Loss of Dok-3 in Non-tumor Cells Induces Malignant Transformation of Benign Epithelial Tumor Cells of the Intestine

Sumimasa Arimura, Akane Inoue-Yamauchi, Kotoe Katayama, Tatsuo Kanno, Hiroki Jozawa, Seiya Imoto, Yuji Yamanashi

Cancer Res Commun. 2022 Dec; 2(12): 1590–1600. Published online 2022 Dec 8. doi: 10.1158/2767-9764.CRC-22-0347

PMCID:: PMC10035524

Abstract Article PDF–12M

Select item 95107822.

Dok3 restrains neutrophil production of calprotectin during TLR4 sensing of SARS-CoV-2 spike protein

Jia Tong Loh, Joey Kay Hui Teo, Kong-Peng Lam

Front Immunol. 2022; 13: 996637. Published online 2022 Sep 12. doi: 10.3389/fimmu.2022.996637

PMCID:: PMC9510782

Abstract Article PDF–6.9M

Select item 85722823.

DOK3 maintains intestinal homeostasis by suppressing JAK2/STAT3 signaling and S100a8/9 production in neutrophils

Jia Tong Loh, Koon-Guan Lee, Alison P. Lee, Joey Kay Hui Teo, Hsueh Lee Lim, Susana Soo-Yeon Kim, Andy Hee-Meng Tan, Kong-Peng Lam

Cell Death Dis. 2021 Nov; 12(11): 1054. Published online 2021 Nov 6. doi: 10.1038/s41419-021-04357-5

PMCID:: PMC8572282

Abstract Article PDF–2.9M

Select item 78350114.

DOK3 is involved in microglial cell activation in neuropathic pain by interacting with GPR84

Wen-Shuang Gao, Yu-Juan Qu, Juan Huai, Hui Wei, Yang Zhang, Shou-Wei Yue

Aging (Albany NY) 2021 Jan 15; 13(1): 389–410. Published online 2020 Dec 3. doi: 10.18632/aging.202144

PMCID:: PMC7835011

Abstract Article PDF–2.5M

Select item 74159915.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 70775946.

Vitamin B6 inhibits macrophage activation to prevent lipopolysaccharide‐induced acute pneumonia in mice

Mei‐Rong Shan, Sheng‐Nan Zhou, Chang‐Ning Fu, Jia‐Wen Song, Xue‐Qing Wang, Wen‐Wu Bai, Peng Li, Ping Song, Mo‐Li Zhu, Zhi‐Min Ma, Zhan Liu, Jian Xu, Bo Dong, Chao Liu, Tao Guo, Cheng Zhang, Shuang‐Xi Wang

J Cell Mol Med. 2020 Mar; 24(5): 3139–3148. Published online 2020 Jan 22. doi: 10.1111/jcmm.14983

PMCID:: PMC7077594

Abstract Article PDF–1.1M

Select item 66606557.

Dok-3 deficient mice display different immune clustering and Tim-3 expression

Wenjiang Yan, Yijia Tian, Peng Sun, Jingjing Yang, Na Li, Yuanyuan Sun, Shuangxi Wang, Cheng Zhang

Eur J Med Res. 2019; 24: 26. Published online 2019 Jul 27. doi: 10.1186/s40001-019-0384-7

PMCID:: PMC6660655

Abstract Article PDF–2.8M

Select item 65972448.

Dok3–protein phosphatase 1 interaction attenuates Card9 signaling and neutrophil-dependent antifungal immunity

Jia Tong Loh, Shengli Xu, Jian Xin Huo, Susana Soo-Yeon Kim, Yue Wang, Kong-Peng Lam

J Clin Invest. 2019 Jul 1; 129(7): 2717–2729. Published online 2019 Jun 10. doi: 10.1172/JCI126341

PMCID:: PMC6597244

Abstract Article PDF–10M

Select item 56858779.

DOK3 Modulates Bone Remodeling by Negatively Regulating Osteoclastogenesis and Positively Regulating Osteoblastogenesis

Xiaofeng Cai, Junjie Xing, Courtney L Long, Qisheng Peng, Mary Beth Humphrey

J Bone Miner Res. Author manuscript; available in PMC 2017 Nov 15.

Published in final edited form as: J Bone Miner Res. 2017 Nov; 32(11): 2207–2218. Published online 2017 Aug 2. doi: 10.1002/jbmr.3205

PMCID:: PMC5685877

Abstract Article PDF–1.1M

Select item 566060710.

A functional genomics predictive network model identifies regulators of inflammatory bowel disease

Lauren A Peters, Jacqueline Perrigoue, Arthur Mortha, Alina Iuga, Won-min Song, Eric M Neiman, Sean R Llewellyn, Antonio Di Narzo, Brian A Kidd, Shannon E Telesco, Yongzhong Zhao, Aleksandar Stojmirovic, Jocelyn Sendecki, Khader Shameer, Riccardo Miotto, Bojan Losic, Hardik Shah, Eunjee Lee, Minghui Wang, Jeremiah J Faith, Andrew Kasarskis, Carrie Brodmerkel, Mark Curran, Anuk Das, Joshua R Friedman, Yoshinori Fukui, Mary Beth Humphrey, Brian M Iritani, Nicholas Sibinga, Teresa K Tarrant, Carmen Argmann, Ke Hao, Panos Roussos, Jun Zhu, Bin Zhang, Radu Dobrin, Lloyd F Mayer, Eric E Schadt

Nat Genet. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: Nat Genet. 2017 Oct; 49(10): 1437–1449. Published online 2017 Sep 11. doi: 10.1038/ng.3947

PMCID:: PMC5660607

Abstract Article PDF–1.6M

Select item 412813611.

Adaptor protein DOK3 promotes plasma cell differentiation by regulating the expression of programmed cell death 1 ligands

Xijun Ou, Shengli Xu, Yan-Feng Li, Kong-Peng Lam

Proc Natl Acad Sci U S A. 2014 Aug 5; 111(31): 11431–11436. Published online 2014 Jul 22. doi: 10.1073/pnas.1400539111

PMCID:: PMC4128136

Abstract Article PDF–1.4M

Select item 392330812.

A Physical Interaction Between the Adaptor Proteins DOK3 and DAP12 Is Required to Inhibit Lipopolysaccharide Signaling in Macrophages

Qisheng Peng, Courtney L. Long, Shikha Malhotra, Mary Beth Humphrey

Sci Signal. Author manuscript; available in PMC 2014 Feb 13.

Published in final edited form as: Sci Signal. 2013 Aug 20; 6(289): ra72. Published online 2013 Aug 20. doi: 10.1126/scisignal.2003801

PMCID:: PMC3923308

Abstract Article PDF–3.7M

Select item 338462913.

DOK3 Negatively Regulates LPS Responses and Endotoxin Tolerance

Qisheng Peng, Jason L. O’Loughlin, Mary Beth Humphrey

PLoS One. 2012; 7(6): e39967. Published online 2012 Jun 27. doi: 10.1371/journal.pone.0039967

PMCID:: PMC3384629

Abstract Article PDF–4.5M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253415.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 295644316.

Identification of DOK family genes as lung tumor suppressors

Alice H. Berger, Masaru Niki, Alessandro Morotti, Barry S. Taylor, Nicholas D. Socci, Agnes Viale, Cameron Brennan, Janos Szoke, Noriko Motoi, Paul B. Rothman, Julie Teruya-Feldstein, William L. Gerald, Marc Ladanyi, Pier Paolo Pandolfi

Nat Genet. Author manuscript; available in PMC 2010 Oct 18.

Published in final edited form as: Nat Genet. 2010 Mar; 42(3): 216–223. Published online 2010 Feb 7. doi: 10.1038/ng.527

PMCID:: PMC2956443

Abstract Article PDF–3.5M

Select item 215077017.

Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation

Jan Grimm, Martin Sachs, Stefan Britsch, Silvana Di Cesare, Thomas Schwarz-Romond, Kari Alitalo, Walter Birchmeier

J Cell Biol. 2001 Jul 23; 154(2): 345–354. doi: 10.1083/jcb.200102032

PMCID:: PMC2150770

Abstract Article PDF–545K

Select item 185282918.

Subcellular localization of Grb2 by the adaptor protein Dok-3 restricts the intensity of Ca²⁺ signaling in B cells

Björn Stork, Konstantin Neumann, Ingo Goldbeck, Sebastian Alers, Thilo Kähne, Michael Naumann, Michael Engelke, Jürgen Wienands

EMBO J. 2007 Feb 21; 26(4): 1140–1149. Published online 2007 Feb 8. doi: 10.1038/sj.emboj.7601557

PMCID:: PMC1852829

Abstract Article PDF–396K

Select item 146298719.

Interaction of Moloney murine leukemia virus matrix protein with IQGAP

Juliana Leung, Andrew Yueh, Frank S K Appah, Jr, Bing Yuan, Kenia de los Santos, Stephen P Goff

EMBO J. 2006 May 17; 25(10): 2155–2166. Published online 2006 Apr 20. doi: 10.1038/sj.emboj.7601097

PMCID:: PMC1462987

Abstract Article PDF–231K

Select item 141356820.

BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System

Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran

PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086

PMCID:: PMC1413568

Article PDF–99K

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