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Select item 111905731.

TBX3 is essential for establishment of the posterior boundary of anterior genes and upregulation of posterior genes together with HAND2 during the onset of limb bud development

Geoffrey Soussi, Ausra Girdziusaite, Shalu Jhanwar, Victorio Palacio, Marco Notaro, Rushikesh Sheth, Rolf Zeller, Aimée Zuniga

Development. 2024 Jun 1; 151(11): dev202722. Published online 2024 Jun 3. doi: 10.1242/dev.202722

PMCID:: PMC11190573

Abstract Article

Select item 105892972.

Hnrnpk is essential for embryonic limb bud development as a transcription activator and a collaborator of insulator protein Ctcf

Yuyu Chen, Taifeng Zhou, Zhiheng Liao, Wenjie Gao, Jinna Wu, Shun Zhang, Yongyong Li, Hengyu Liu, Hang Zhou, Caixia Xu, Peiqiang Su

Cell Death Differ. 2023 Oct; 30(10): 2293–2308. Published online 2023 Aug 22. doi: 10.1038/s41418-023-01207-z

PMCID:: PMC10589297

Abstract Article PDF–16M

Select item 103904923.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 99414694.

A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis

Lishan Zhang, Ziqi Fang, Guangdong Cheng, Mengting He, Yanliang Lin

Cell Death Dis. 2023 Feb; 14(2): 145. Published online 2023 Feb 20. doi: 10.1038/s41419-023-05681-8

PMCID:: PMC9941469

Abstract Article PDF–4.4M

Select item 93043415.

Etv2 regulates enhancer chromatin status to initiate Shh expression in the limb bud

Naoko Koyano-Nakagawa, Wuming Gong, Satyabrata Das, Joshua W. M. Theisen, Tran B. Swanholm, Daniel Van Ly, Nikita Dsouza, Bhairab N. Singh, Hiroko Kawakami, Samantha Young, Katherine Q. Chen, Yasuhiko Kawakami, Daniel J. Garry

Nat Commun. 2022; 13: 4221. Published online 2022 Jul 21. doi: 10.1038/s41467-022-31848-6

PMCID:: PMC9304341

Abstract Article PDF–5.7M

Select item 92497886.

DDX1 vesicles control calcium-dependent mitochondrial activity in mouse embryos

Yixiong Wang, Lubna Yasmin, Lei Li, Pinzhang Gao, Xia Xu, Xuejun Sun, Roseline Godbout

Nat Commun. 2022; 13: 3794. Published online 2022 Jul 1. doi: 10.1038/s41467-022-31497-9

PMCID:: PMC9249788

Abstract Article PDF–8.3M

Select item 92058577.

Context-dependent enhancer function revealed by targeted inter-TAD relocation

Christopher Chase Bolt, Lucille Lopez-Delisle, Aurélie Hintermann, Bénédicte Mascrez, Antonella Rauseo, Guillaume Andrey, Denis Duboule

Nat Commun. 2022; 13: 3488. Published online 2022 Jun 17. doi: 10.1038/s41467-022-31241-3

PMCID:: PMC9205857

Abstract Article PDF–2.3M

Select item 86129988.

Genetic basis for an evolutionary shift from ancestral preaxial to postaxial limb polarity in non-urodele vertebrates

Anna Trofka, Bau-Lin Huang, Jianjian Zhu, William F Heinz, Valentin Magidson, Yuki Shibata, Yun-Bo Shi, Basile Tarchini, H Scott Stadler, Mirindi Kabangu, Nour W Al Haj Baddar, S. Randal Voss, Susan Mackem

Curr Biol. Author manuscript; available in PMC 2022 Nov 22.

Published in final edited form as: Curr Biol. 2021 Nov 22; 31(22): 4923–4934.e5. Published online 2021 Oct 4. doi: 10.1016/j.cub.2021.09.010

PMCID:: PMC8612998

Abstract Article PDF–2.7M

Select item 85288199.

Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient

Satomi Yogosawa, Makiko Ohkido, Takuro Horii, Yasumasa Okazaki, Jun Nakayama, Saishu Yoshida, Shinya Toyokuni, Izuho Hatada, Mitsuru Morimoto, Kiyotsugu Yoshida

Commun Biol. 2021; 4: 1204. Published online 2021 Oct 20. doi: 10.1038/s42003-021-02734-6

PMCID:: PMC8528819

Abstract Article PDF–3.6M

Select item 847907110.

Conserved and species-specific chromatin remodeling and regulatory dynamics during mouse and chicken limb bud development

Shalu Jhanwar, Jonas Malkmus, Jens Stolte, Olga Romashkina, Aimée Zuniga, Rolf Zeller

Nat Commun. 2021; 12: 5685. Published online 2021 Sep 28. doi: 10.1038/s41467-021-25935-3

PMCID:: PMC8479071

Abstract Article PDF–3.9M

Select item 845176011.

Dbx2 regulation in limbs suggests interTAD sharing of enhancers

Leonardo Beccari, Gabriel Jaquier, Lucille Lopez‐Delisle, Eddie Rodriguez‐Carballo, Bénédicte Mascrez, Sandra Gitto, Joost Woltering, Denis Duboule

Dev Dyn. 2021 Sep; 250(9): 1280–1299. Published online 2021 Mar 1. doi: 10.1002/dvdy.303

PMCID:: PMC8451760

Abstract Article PDF–16M

Select item 837884812.

Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner

Sun-Hee Hwang, Bandarigoda N Somatilaka, Kevin White, Saikat Mukhopadhyay

eLife. 2021; 10: e67121. Published online 2021 Aug 4. doi: 10.7554/eLife.67121

PMCID:: PMC8378848

Abstract Article PDF–9.0M

Select item 837393113.

Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations

Christopher Chase Bolt, Lucille Lopez-Delisle, Bénédicte Mascrez, Denis Duboule

Nat Commun. 2021; 12: 5013. Published online 2021 Aug 18. doi: 10.1038/s41467-021-25330-y

PMCID:: PMC8373931

Abstract Article PDF–3.1M

Select item 836229114.

Geminin is required for Hox gene regulation to pattern the developing limb

Emily M.A. Lewis, Savita Sankar, Caili Tong, Ethan Patterson, Laura E. Waller, Paul Gontarz, Bo Zhang, David M. Ornitz, Kristen L. Kroll

Dev Biol. Author manuscript; available in PMC 2021 Aug 13.

Published in final edited form as: Dev Biol. 2020 Aug 1; 464(1): 11–23. Published online 2020 May 23. doi: 10.1016/j.ydbio.2020.05.007

PMCID:: PMC8362291

Abstract Article PDF–2.6M

Select item 782316315.

Androgen action in cell fate and communication during prostate development at single-cell resolution

Dong-Hoon Lee, Adam W. Olson, Jinhui Wang, Won Kyung Kim, Jiaqi Mi, Hong Zeng, Vien Le, Joseph Aldahl, Alex Hiroto, Xiwei Wu, Zijie Sun

Development. 2021 Jan 1; 148(1): dev196048. Published online 2021 Jan 11. doi: 10.1242/dev.196048

PMCID:: PMC7823163

Abstract Article

Select item 771000316.

Atlas of Musculoskeletal Stem Cells with the Soft and Hard Tissue Differentiation Architecture

Zi Yin, Junxin Lin, Ruojin Yan, Richun Liu, Mengfei Liu, Bo Zhou, Wenyan Zhou, Chengrui An, Yangwu Chen, Yejun Hu, Chunmei Fan, Kun Zhao, Bingbing Wu, Xiaohui Zou, Jin Zhang, Ahmed H. El‐Hashash, Xiao Chen, Hongwei Ouyang

Adv Sci (Weinh) 2020 Dec; 7(23): 2000938. Published online 2020 Oct 22. doi: 10.1002/advs.202000938

PMCID:: PMC7710003

Abstract Article PDF–16M

Select item 770466617.

Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster

Yoshiki Higashijima, Nao Nagai, Masamichi Yamamoto, Taro Kitazawa, Yumiko K. Kawamura, Akashi Taguchi, Natsuko Nakada, Masaomi Nangaku, Tetsushi Furukawa, Hiroyuki Aburatani, Hiroki Kurihara, Youichiro Wada, Yasuharu Kanki

Commun Biol. 2020; 3: 725. Published online 2020 Nov 30. doi: 10.1038/s42003-020-01456-5

PMCID:: PMC7704666

Abstract Article PDF–1.3M

Select item 767365218.

TLR2/6 signaling promotes the expansion of premalignant hematopoietic stem and progenitor cells in the NUP98-HOXD13 mouse model of MDS

Darlene A. Monlish, Zev J. Greenberg, Sima T. Bhatt, Kathryn M. Leonard, Molly P. Romine, Qian Dong, Lauren Bendesky, Eric J. Duncavage, Jeffrey A. Magee, Laura G. Schuettpelz

Exp Hematol. Author manuscript; available in PMC 2020 Nov 18.

Published in final edited form as: Exp Hematol. 2020 Aug; 88: 42–55. Published online 2020 Jul 8. doi: 10.1016/j.exphem.2020.07.001

PMCID:: PMC7673652

Abstract Article PDF–2.1M

Select item 764037319.

Brief Report: Loss of p15Ink4b Accelerates Development of Myeloid Neoplasms in Nup98-HoxD13 Transgenic Mice

Rita Humeniuk, Richard Koller, Juraj Bies, Peter Aplan, Linda Wolff

Stem Cells. Author manuscript; available in PMC 2020 Nov 4.

Published in final edited form as: Stem Cells. 2014 May; 32(5): 1361–1366. doi: 10.1002/stem.1635

PMCID:: PMC7640373

Abstract Article PDF–1.0M

Select item 725995120.

Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates

Tempei Sato, Kensuke Kataoka, Yoshiaki Ito, Shigetoshi Yokoyama, Masafumi Inui, Masaki Mori, Satoru Takahashi, Keiichi Akita, Shuji Takada, Hiroe Ueno-Kudoh, Hiroshi Asahara

eLife. 2020; 9: e53608. Published online 2020 May 29. doi: 10.7554/eLife.53608