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Items: 1 to 20 of 63

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Probing protein ubiquitination in live cells
Weihua Qin, Clemens Steinek, Ksenia Kolobynina, Ignasi Forné, Axel Imhof, M Cristina Cardoso, Heinrich Leonhardt
Nucleic Acids Res. 2022 Nov 28; 50(21): e125. Published online 2022 Oct 3. doi: 10.1093/nar/gkac805
PMCID:
PMC9757074
AbstractArticlePDF–8.2M
3.
Phosphorylation of the HP1β hinge region sequesters KAP1 in heterochromatin and promotes the exit from naïve pluripotency
Weihua Qin, Enes Ugur, Christopher B Mulholland, Sebastian Bultmann, Irina Solovei, Miha Modic, Martha Smets, Michael Wierer, Ignasi Forné, Axel Imhof, M Cristina Cardoso, Heinrich Leonhardt
Nucleic Acids Res. 2021 Jul 21; 49(13): 7406–7423. Published online 2021 Jul 2. doi: 10.1093/nar/gkab548
PMCID:
PMC8287961
AbstractArticlePDF–5.6M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
5.
Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells
Samudyata, Paulo P. Amaral, Pär G. Engström, Samuel C. Robson, Michael L. Nielsen, Tony Kouzarides, Gonçalo Castelo-Branco
Exp Cell Res. Author manuscript; available in PMC 2020 Aug 1.
Published in final edited form as: Exp Cell Res. 2019 Aug 1; 381(1): 129–138. Published online 2019 May 9. doi: 10.1016/j.yexcr.2019.05.006
PMCID:
PMC6994247
AbstractArticlePDF–1.6M
6.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
7.
An atlas of genetic influences on osteoporosis in humans and mice
John A. Morris, John P. Kemp, Scott E. Youlten, Laetitia Laurent, John G. Logan, Ryan C. Chai, Nicholas A. Vulpescu, Vincenzo Forgetta, Aaron Kleinman, Sindhu T. Mohanty, C. Marcelo Sergio, Julian Quinn, Loan Nguyen-Yamamoto, Aimee-Lee Luco, Jinchu Vijay, Marie-Michelle Simon, Albena Pramatarova, Carolina Medina-Gomez, Katerina Trajanoska, Elena J. Ghirardello, Natalie C. Butterfield, Katharine F. Curry, Victoria D. Leitch, Penny C. Sparkes, Anne-Tounsia Adoum, Naila S. Mannan, Davide S.K. Komla-Ebri, Andrea S. Pollard, Hannah F. Dewhurst, Thomas A.D. Hassall, Michael-John G. Beltejar, 23andMe Research Team, Douglas J. Adams, Suzanne M. Vaillancourt, Stephen Kaptoge, Paul Baldock, Cyrus Cooper, Jonathan Reeve, Evangelia E. Ntzani, Evangelos Evangelou, Claes Ohlsson, David Karasik, Fernando Rivadeneira, Douglas P. Kiel, Jonathan H. Tobias, Celia L. Gregson, Nicholas C. Harvey, Elin Grundberg, David Goltzman, David J. Adams, Christopher J. Lelliott, David A. Hinds, Cheryl L. Ackert-Bicknell, Yi-Hsiang Hsu, Matthew T. Maurano, Peter I. Croucher, Graham R. Williams, J. H. Duncan Bassett, David M. Evans, J. Brent Richards
Nat Genet. Author manuscript; available in PMC 2019 Jun 30.
Published in final edited form as: Nat Genet. 2019 Feb; 51(2): 258–266. Published online 2018 Dec 31. doi: 10.1038/s41588-018-0302-x
PMCID:
PMC6358485
AbstractArticlePDF–1.8M
8.
An efficient method for generation of bi-allelic null mutant mouse embryonic stem cells and its application for investigating epigenetic modifiers
Cynthia L. Fisher, Hendrik Marks, Lily Ting-yin Cho, Robert Andrews, Sam Wormald, Thomas Carroll, Vivek Iyer, Peri Tate, Barry Rosen, Hendrik G. Stunnenberg, Amanda G. Fisher, William C. Skarnes
Nucleic Acids Res. 2017 Dec 1; 45(21): e174. Published online 2017 Sep 13. doi: 10.1093/nar/gkx811
PMCID:
PMC5716182
AbstractArticlePDF–3.8M
9.
A staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5)
Stefan H. Geyer, Lukas Reissig, Julia Rose, Robert Wilson, Fabrice Prin, Dorota Szumska, Ramiro Ramirez‐Solis, Catherine Tudor, Jacqui White, Timothy J. Mohun, Wolfgang J. Weninger
J Anat. 2017 May; 230(5): 710–719. Published online 2017 Feb 9. doi: 10.1111/joa.12590
PMCID:
PMC5382591
AbstractArticlePDF–1.5M
10.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
11.
An HP1 isoform-specific feedback mechanism regulates Suv39h1 activity under stress conditions
Helena Raurell-Vila, Laia Bosch-Presegue, Jessica Gonzalez, Noriko Kane-Goldsmith, Carmen Casal, Jeremy P. Brown, Anna Marazuela-Duque, Prim B. Singh, Lourdes Serrano, Alejandro Vaquero
Epigenetics. 2017; 12(2): 166–175. Published online 2017 Jan 6. doi: 10.1080/15592294.2016.1278096
PMCID:
PMC5330444
AbstractArticlePDF–1.3M
12.
Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome
Ronghui Li, Qiping Dong, Xinni Yuan, Xin Zeng, Yu Gao, Cassandra Chiao, Hongda Li, Xinyu Zhao, Sunduz Keles, Zefeng Wang, Qiang Chang
PLoS Genet. 2016 Jun; 12(6): e1006129. Published online 2016 Jun 28. doi: 10.1371/journal.pgen.1006129
PMCID:
PMC4924826
AbstractArticlePDF–1.9M
13.
Systematic Identification of Factors for Provirus Silencing in Embryonic Stem Cells
Bin Xia Yang, Chadi A. EL Farran, Hong Chao Guo, Tao Yu, Hai Tong Fang, Hao Fei Wang, Sharon Schlesinger, Yu Fen Samantha Seah, Germaine Yen Lin Goh, Suat Peng Neo, Yinghui Li, Matthew C. Lorincz, Vinay Tergaonkar, Tit-Meng Lim, Lingyi Chen, Jayantha Gunaratne, James J. Collins, Stephen P. Goff, George Q. Daley, Hu Li, Frederic A. Bard, Yuin-Han Loh
Cell. Author manuscript; available in PMC 2015 Dec 21.
Published in final edited form as: Cell. 2015 Sep 24; 163(1): 230–245. Published online 2015 Sep 10. doi: 10.1016/j.cell.2015.08.037
PMCID:
PMC4686136
AbstractArticlePDF–1.2M
14.
Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells
Anna Mattout, Yair Aaronson, Badi Sri Sailaja, Edupuganti V. Raghu Ram, Arigela Harikumar, Jan-Philipp Mallm, Kae Hwan Sim, Malka Nissim-Rafinia, Emmanuelle Supper, Prim B. Singh, Siu Kwan Sze, Susan M. Gasser, Karsten Rippe, Eran Meshorer
Genome Biol. 2015; 16: 213. Published online 2015 Sep 28. doi: 10.1186/s13059-015-0760-8
PMCID:
PMC4587738
AbstractArticlePDF–4.5M
15.
Functional Proteomic Analysis of Repressive Histone Methyltransferase Complexes Reveals ZNF518B as a G9A Regulator
Verena K. Maier, Caitlin M. Feeney, Jordan E. Taylor, Amanda L. Creech, Jana W. Qiao, Attila Szanto, Partha P. Das, Nicholas Chevrier, Catherine Cifuentes-Rojas, Stuart H. Orkin, Steven A. Carr, Jacob D. Jaffe, Philipp Mertins, Jeannie T. Lee
Mol Cell Proteomics. 2015 Jun; 14(6): 1435–1446. Published online 2015 Feb 13. doi: 10.1074/mcp.M114.044586
PMCID:
PMC4458711
AbstractArticlePDF–2.6M
16.
Proteomic and genomic approaches reveal critical functions of H3K9 methylation and Heterochromatin Protein-1? in reprogramming to pluripotency
Rupa Sridharan, Michelle Gonzales-Cope, Constantinos Chronis, Giancarlo Bonora, Robin McKee, Chengyang Huang, Sanjeet Patel, David Lopez, Nilamadhab Mishra, Matteo Pellegrini, Michael Carey, Benjamin A. Garcia, Kathrin Plath
Nat Cell Biol. Author manuscript; available in PMC 2014 Jan 1.
Published in final edited form as: Nat Cell Biol. 2013 Jul; 15(7): 872–882. Published online 2013 Jun 9. doi: 10.1038/ncb2768
PMCID:
PMC3733997
AbstractArticlePDF–1.6M
17.
Developmentally Regulated Linker Histone H1c Promotes Heterochromatin Condensation and Mediates Structural Integrity of Rod Photoreceptors in Mouse Retina
Evgenya Y. Popova, Sergei A. Grigoryev, Yuhong Fan, Arthur I. Skoultchi, Samuel S. Zhang, Colin J. Barnstable
J Biol Chem. 2013 Jun 14; 288(24): 17895–17907. Published online 2013 May 3. doi: 10.1074/jbc.M113.452144
PMCID:
PMC3682587
AbstractArticlePDF–3.6M
18.
The Polycomb Group Protein L3mbtl2 Assembles an Atypical PRC1-Family Complex that Is Essential in Pluripotent Stem Cells and Early Development
Jinzhong Qin, Warren A. Whyte, Endre Anderssen, Effie Apostolou, Hsu-Hsin Chen, Schahram Akbarian, Roderick T. Bronson, Konrad Hochedlinger, Sridhar Ramaswamy, Richard A. Young, Hanno Hock
Cell Stem Cell. Author manuscript; available in PMC 2013 May 8.
Published in final edited form as: Cell Stem Cell. 2012 Sep 7; 11(3): 319–332. Published online 2012 Jul 5. doi: 10.1016/j.stem.2012.06.002
PMCID:
PMC3647456
AbstractArticlePDF–5.1M
19.
Heterochromatin protein 1 promotes self-renewal and triggers regenerative proliferation in adult stem cells
An Zeng, Yong-Qin Li, Chen Wang, Xiao-Shuai Han, Ge Li, Jian-Yong Wang, Dang-Sheng Li, Yong-Wen Qin, Yufang Shi, Gary Brewer, Qing Jing
J Cell Biol. 2013 Apr 29; 201(3): 409–425. doi: 10.1083/jcb.201207172
PMCID:
PMC3639387
AbstractArticlePDF–6.4M
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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