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Items: 1 to 20 of 51

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Type 2 diabetes susceptibility gene GRK5 regulates physiological pancreatic β-cell proliferation via phosphorylation of HDAC5
Shugo Sasaki, Cuilan Nian, Eric E. Xu, Daniel J. Pasula, Helena Winata, Sanya Grover, Dan S. Luciani, Francis C. Lynn
iScience. 2023 Aug 18; 26(8): 107311. Published online 2023 Jul 10. doi: 10.1016/j.isci.2023.107311
PMCID:
PMC10382860
AbstractArticlePDF–2.0M
3.
GRK5‐mediated inflammation and fibrosis exert cardioprotective effects during the acute phase of myocardial infarction
Akiomi Nagasaka, Tsuyoshi Terawaki, Makoto Noda, Miyuki Takashima, Mika Fujino, Yuto Yamauchi, Shigeki Arawaka, Takeo Kato, Michio Nakaya
FEBS Open Bio. 2023 Feb; 13(2): 380–391. Published online 2023 Jan 20. doi: 10.1002/2211-5463.13551
PMCID:
PMC9900089
AbstractArticlePDF–1.3M
4.
Combinatorial depletions of G-protein coupled receptor kinases in immune cells identify pleiotropic and cell type-specific functions
Katharina M. Glaser, Teresa K. Tarrant, Tim Lämmermann
Front Immunol. 2022; 13: 1039803. Published online 2022 Nov 14. doi: 10.3389/fimmu.2022.1039803
PMCID:
PMC9703078
AbstractArticlePDF–20M
5.
G protein-coupled receptor kinase 5 (GRK5) contributes to impaired cardiac function and immune cell recruitment in post-ischemic heart failure
Claudio de Lucia, Laurel A Grisanti, Giulia Borghetti, Michela Piedepalumbo, Jessica Ibetti, Anna Maria Lucchese, Eric W Barr, Rajika Roy, Ama Dedo Okyere, Haley Christine Murphy, Erhe Gao, Giuseppe Rengo, Steven R Houser, Douglas G Tilley, Walter J Koch
Cardiovasc Res. 2022 Jan; 118(1): 169–183. Published online 2021 Feb 9. doi: 10.1093/cvr/cvab044
PMCID:
PMC8752360
AbstractArticlePDF–2.3M
6.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
7.
A peptide of the N-terminus of GRK5 attenuates pressure-overload hypertrophy and heart failure
Ryan C. Coleman, Akito Eguchi, Melissa Lieu, Rajika Roy, Eric W. Barr, Jessica Ibetti, Anna-Maria Lucchese, Amanda M. Peluzzo, Kenneth Gresham, J. Kurt Chuprun, Walter J. Koch
Sci Signal. Author manuscript; available in PMC 2021 Sep 30.
Published in final edited form as: Sci Signal. 2021 Mar 30; 14(676): eabb5968. Published online 2021 Mar 30. doi: 10.1126/scisignal.abb5968
PMCID:
PMC8092419
AbstractArticlePDF–1.6M
8.
GRK5 is a regulator of fibroblast activation and cardiac fibrosis
Akito Eguchi, Ryan Coleman, Kenneth Gresham, Erhe Gao, Jessica Ibetti, J. Kurt Chuprun, Walter J. Koch
Proc Natl Acad Sci U S A. 2021 Feb 2; 118(5): e2012854118. Published online 2021 Jan 26. doi: 10.1073/pnas.2012854118
PMCID:
PMC7865138
AbstractArticlePDF–3.5M
9.
GRK5 Controls SAP97-Dependent Cardiotoxic β1 Adrenergic Receptor-CaMKII Signaling in Heart Failure
Bing Xu, Minghui Li, Ying Wang, Meimi Zhao, Stefano Morotti, Qian Shi, Qingtong Wang, Federica Barbagallo, Jian-Peng Teoh, Gopireddy R. Reddy, Elizabeth F. Bayne, Yongming Liu, Ao Shen, Jose L. Puglisi, Ying Ge, Ji Li, Eleonora Grandi, Madeline Nieves-Cintron, Yang K. Xiang
Circ Res. Author manuscript; available in PMC 2021 Aug 28.
Published in final edited form as: Circ Res. 2020 Aug 28; 127(6): 796–810. Published online 2020 Jun 8. doi: 10.1161/CIRCRESAHA.119.316319
PMCID:
PMC7484403
AbstractArticlePDF–2.7M
10.
Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics
Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea
Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253
PMCID:
PMC6692770
AbstractArticlePDF–7.7M
11.
ATG5 is required for B cell polarization and presentation of particulate antigens
Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros
Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327
PMCID:
PMC6333460
AbstractArticlePDF–2.7M
12.
G-protein receptor kinases 2, 5 and 6 redundantly modulate Smoothened-GATA transcriptional crosstalk in fetal mouse hearts
Antonietta Franco, Lihong Zhang, Scot J. Matkovich, Attila Kovacs, Gerald W Dorn, II
J Mol Cell Cardiol. Author manuscript; available in PMC 2019 Aug 1.
Published in final edited form as: J Mol Cell Cardiol. 2018 Aug; 121: 60–68. Published online 2018 Jun 30. doi: 10.1016/j.yjmcc.2018.06.009
PMCID:
PMC6178805
AbstractArticlePDF–1.1M
13.
β-arrestin-biased agonism of β-adrenergic receptor regulates Dicer-mediated microRNA maturation to promote cardioprotective signaling
Jian-peng Teoh, Ahmed S. Bayoumi, Tatsuya Aonuma, Yanyan Xu, John A. Johnson, Huabo Su, Neal L. Weintraub, Yaoliang Tang, Il-man Kim
J Mol Cell Cardiol. Author manuscript; available in PMC 2019 May 1.
Published in final edited form as: J Mol Cell Cardiol. 2018 May; 118: 225–236. Published online 2018 Apr 6. doi: 10.1016/j.yjmcc.2018.04.001
PMCID:
PMC5940519
AbstractArticlePDF–1.3M
14.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
15.
GRK5 deficiency leads to susceptibility to intermittent hypoxia-induced cognitive impairment
Prabhakar Singh, Wei Peng, Qiang Zhang, XueFeng Ding, William Z. Suo
Behav Brain Res. Author manuscript; available in PMC 2017 Apr 1.
Published in final edited form as: Behav Brain Res. 2016 Apr 1; 302: 29–34. Published online 2016 Jan 8. doi: 10.1016/j.bbr.2016.01.019
PMCID:
PMC5068244
AbstractArticlePDF–1.3M
16.
GRK5 Deficiency Leads to Selective Basal Forebrain Cholinergic Neuronal Vulnerability
Minchao He, Prabhakar Singh, Shaowu Cheng, Qiang Zhang, Wei Peng, XueFeng Ding, Longxuan Li, Jun Liu, Richard T. Premont, Dave Morgan, Jeffery M. Burns, Russell H. Swerdlow, William Z. Suo
Sci Rep. 2016; 6: 26116. Published online 2016 May 19. doi: 10.1038/srep26116
PMCID:
PMC4872166
AbstractArticlePDF–2.1M
17.
Bacterial Dose-Dependent Role of G Protein-Coupled Receptor Kinase 5 in Escherichia coli-Induced Pneumonia
Nandakumar Packiriswamy, Michael Steury, Ian C. McCabe, Scott D. Fitzgerald, Narayanan Parameswaran
Infect Immun. 2016 May; 84(5): 1633–1641. Prepublished online 2016 Mar 14. Published online 2016 Apr 22. doi: 10.1128/IAI.00051-16
PMCID:
PMC4862718
AbstractArticlePDF–1.7M
18.
Differential Role of G Protein-Coupled Receptor Kinase 5 in Physiological Versus Pathological Cardiac Hypertrophy
Christopher J. Traynham, Alessandro Cannavo, Yan Zhou, Alexandre G. Vouga, Benjamin P. Woodall, Jonathan Hullmann, Jessica Ibetti, Jessica I. Gold, J. Kurt Chuprun, Erhe Gao, Walter J. Koch
Circ Res. Author manuscript; available in PMC 2016 Dec 4.
Published in final edited form as: Circ Res. 2015 Dec 4; 117(12): 1001–1012. Published online 2015 Oct 29. doi: 10.1161/CIRCRESAHA.115.306961
PMCID:
PMC4825669
AbstractArticlePDF–706K
19.
GRK5-Mediated Exacerbation of Pathological Cardiac Hypertrophy Involves Facilitation of Nuclear NFAT Activity
Jonathan E. Hullmann, Laurel A. Grisanti, Catherine A. Makarewich, Erhe Gao, Jessica I. Gold, J. Kurt Chuprun, Douglass G. Tilley, Steven R. Houser, Walter J. Koch
Circ Res. Author manuscript; available in PMC 2015 Dec 5.
Published in final edited form as: Circ Res. 2014 Dec 5; 115(12): 976–985. Published online 2014 Oct 20. doi: 10.1161/CIRCRESAHA.116.304475
PMCID:
PMC4258119
AbstractArticlePDF–1.3M
20.
Loss of Morphine Reward and Dependence in Mice Lacking G Protein-Coupled Receptor Kinase 5
Laura Glück, Anastasia Loktev, Lionel Moulédous, Catherine Mollereau, Ping-Yee Law, Stefan Schulz
Biol Psychiatry. Author manuscript; available in PMC 2015 Nov 15.
Published in final edited form as: Biol Psychiatry. 2014 Nov 15; 76(10): 767–774. Published online 2014 Feb 3. doi: 10.1016/j.biopsych.2014.01.021
PMCID:
PMC4119866
AbstractArticlePDF–644K

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