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Items: 1 to 20 of 42

1.
Disruption of the autism gene and chromatin regulator KDM5A alters hippocampal cell identity
Lauretta El Hayek, Darlene DeVries, Ashlesha Gogate, Ariel Aiken, Kiran Kaur, Maria H. Chahrour
Sci Adv. 2023 Nov 24; 9(47): eadi0074. Published online 2023 Nov 22. doi: 10.1126/sciadv.adi0074
PMCID:
PMC10664992
AbstractArticlePDF–1.4M
2.
Aβ-induced mitochondrial dysfunction in neural progenitors controls KDM5A to influence neuronal differentiation
Dong Kyu Kim, Hyobin Jeong, Jingi Bae, Moon-Yong Cha, Moonkyung Kang, Dongjin Shin, Shinwon Ha, Seung Jae Hyeon, Hokeun Kim, Kyujin Suh, Mi-Sun Choi, Hoon Ryu, Seong-Woon Yu, Jong-Il Kim, Yeon-Soo Kim, Sang-Won Lee, Daehee Hwang, Inhee Mook-Jung
Exp Mol Med. 2022 Sep; 54(9): 1461–1471. Published online 2022 Sep 2. doi: 10.1038/s12276-022-00841-w
PMCID:
PMC9534996
AbstractArticlePDF–3.5M
3.
Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation
Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley
Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h
PMCID:
PMC8763317
AbstractArticle
4.
Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice
Feng Zhang, Xiong Zhao, Runmin Jiang, Yuying Wang, Xinli Wang, Yu Gu, Longyong Xu, Jing Ye, Charlie Degui Chen, Shuangping Guo, Dawei Zhang, Daqing Zhao
Front Cell Dev Biol. 2021; 9: 642931. Published online 2021 Jul 21. doi: 10.3389/fcell.2021.642931
PMCID:
PMC8333871
AbstractArticlePDF–1.4M
5.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
KDM5A mutations identified in autism spectrum disorder using forward genetics
Lauretta El Hayek, Islam Oguz Tuncay, Nadine Nijem, Jamie Russell, Sara Ludwig, Kiran Kaur, Xiaohong Li, Priscilla Anderton, Miao Tang, Amanda Gerard, Anja Heinze, Pia Zacher, Hessa S Alsaif, Aboulfazl Rad, Kazem Hassanpour, Mohammad Reza Abbaszadegan, Camerun Washington, Barbara R DuPont, Raymond J Louie, CAUSES Study, Madeline Couse, Maha Faden, R Curtis Rogers, Rami Abou Jamra, Ellen R Elias, Reza Maroofian, Henry Houlden, Anna Lehman, Bruce Beutler, Maria H Chahrour
eLife. 2020; 9: e56883. Published online 2020 Dec 22. doi: 10.7554/eLife.56883
PMCID:
PMC7755391
AbstractArticlePDF–1.3M
8.
JARID1a Ablation in the Liver Alters Systemic Metabolism and Adaptation to Feeding
Kacee Ann DiTacchio, Diana Kalinowska, Anand Rajamani Saran, Ashley Byrne, Christopher Vollmers, Luciano DiTacchio
Cell Rep. Author manuscript; available in PMC 2020 Jun 20.
Published in final edited form as: Cell Rep. 2020 May 26; 31(8): 107668. doi: 10.1016/j.celrep.2020.107668
PMCID:
PMC7305793
AbstractArticlePDF–2.1M
9.
Histone demethylase KDM5A is transactivated by the transcription factor C/EBPβ and promotes preadipocyte differentiation by inhibiting Wnt/β-catenin signaling
Liang Guo, Ying-Ying Guo, Bai-Yu Li, Wan-Qiu Peng, Qi-Qun Tang
J Biol Chem. 2019 Jun 14; 294(24): 9642–9654. Published online 2019 May 6. doi: 10.1074/jbc.RA119.008419
PMCID:
PMC6579482
AbstractArticlePDF–2.2M
10.
HDAC1 negatively regulates selective mitotic chromatin binding of the Notch effector RBPJ in a KDM5A-dependent manner
Kostiantyn Dreval, Robert J Lake, Hua-Ying Fan
Nucleic Acids Res. 2019 May 21; 47(9): 4521–4538. Published online 2019 Mar 27. doi: 10.1093/nar/gkz178
PMCID:
PMC6511865
AbstractArticlePDF–2.0M
11.
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition
John Arne Dahl, Inkyung Jung, Håvard Aanes, Gareth D. Greggains, Adeel Manaf, Mads Lerdrup, Guoqiang Li, Samantha Kuan, Bin Li, Ah Young Lee, Sebastian Preissl, Ingunn Jermstad, Mads Haugland Haugen, Rajikala Suganthan, Magnar Bjørås, Klaus Hansen, Knut Tomas Dalen, Peter Fedorcsak, Bing Ren, Arne Klungland
Nature. Author manuscript; available in PMC 2018 Dec 6.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 548–552. Published online 2016 Sep 14. doi: 10.1038/nature19360
PMCID:
PMC6283663
AbstractArticlePDF–4.9M
12.
The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1
Gina E. Elsen, Francesco Bedogni, Rebecca D. Hodge, Theo K. Bammler, James W. MacDonald, Susan Lindtner, John L. R. Rubenstein, Robert F. Hevner
Front Neurosci. 2018; 12: 571. Published online 2018 Aug 22. doi: 10.3389/fnins.2018.00571
PMCID:
PMC6113890
AbstractArticlePDF–4.8M
13.
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase
Samuel K. McBrayer, Benjamin A. Olenchock, Gabriel J. DiNatale, Diana D. Shi, Januka Khanal, Rebecca B. Jennings, Jesse S. Novak, Matthew G. Oser, Alissa K. Robbins, Rebecca Modiste, Dennis Bonal, Javid Moslehi, Roderick T. Bronson, Donna Neuberg, Quang-De Nguyen, Sabina Signoretti, Julie-Aurore Losman, William G. Kaelin, Jr.
Proc Natl Acad Sci U S A. 2018 Apr 17; 115(16): E3741–E3748. Published online 2018 Apr 2. doi: 10.1073/pnas.1716029115
PMCID:
PMC5910822
AbstractArticlePDF–1.9M
14.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
15.
KDM5A controls bone morphogenic protein 2-induced osteogenic differentiation of bone mesenchymal stem cells during osteoporosis
Chuandong Wang, Jing Wang, Jiao Li, Guoli Hu, Shengzhou Shan, Qingfeng Li, Xiaoling Zhang
Cell Death Dis. 2016 Aug; 7(8): e2335. Published online 2016 Aug 11. doi: 10.1038/cddis.2016.238
PMCID:
PMC5108323
AbstractArticlePDF–4.1M
16.
Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression
Lori Borgal, Markus M. Rinschen, Claudia Dafinger, Valérie I. Liebrecht, Hinrich Abken, Thomas Benzing, Bernhard Schermer
Cell Cycle. 2016; 15(8): 1034–1045. Published online 2016 Feb 26. doi: 10.1080/15384101.2016.1152429
PMCID:
PMC4889251
AbstractArticlePDF–1.1M
17.
Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells
Renáta Váraljai, Abul B.M.M.K. Islam, Michael L. Beshiri, Jalees Rehman, Nuria Lopez-Bigas, Elizaveta V. Benevolenskaya
Genes Dev. 2015 Sep 1; 29(17): 1817–1834. doi: 10.1101/gad.264036.115
PMCID:
PMC4573855
AbstractArticlePDF–2.5M
18.
Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells
Paulina A. Latos, Angela Goncalves, David Oxley, Hisham Mohammed, Ernest Turro, Myriam Hemberger
Nat Commun. 2015; 6: 7776. Published online 2015 Jul 24. doi: 10.1038/ncomms8776
PMCID:
PMC4525203
AbstractArticlePDF–1.9M
19.
NUP98-PHF23 is a chromatin modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD domain histone reader function
Sheryl M Gough, Fan Lee, Fan Yang, Robert L Walker, Yeulin J Zhu, Marbin Pineda, Masahiro Onozawa, Yang Jo Chung, Sven Bilke, Elise K Wagner, John M Denu, Yi Ning, Bowen Xu, Gang Greg Wang, Paul S Meltzer, Peter D Aplan
Cancer Discov. Author manuscript; available in PMC 2014 Nov 1.
Published in final edited form as: Cancer Discov. 2014 May; 4(5): 564–577. Published online 2014 Feb 17. doi: 10.1158/2159-8290.CD-13-0419
PMCID:
PMC4018760
AbstractArticlePDF–1.4M
20.
Epigenetic regulator RBP2 is critical for breast cancer progression and metastasis
Jian Cao, Zongzhi Liu, William K.C. Cheung, Minghui Zhao, Sophia Y. Chen, Siew Wee Chan, Carmen J. Booth, Don X. Nguyen, Qin Yan
Cell Rep. Author manuscript; available in PMC 2015 Mar 13.
Published in final edited form as: Cell Rep. 2014 Mar 13; 6(5): 868–877. Published online 2014 Feb 27. doi: 10.1016/j.celrep.2014.02.004
PMCID:
PMC4014129
AbstractArticlePDF–2.4M

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