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Select item 108587451.

Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss

Maarja A. Mäe, Liqun He, Sofia Nordling, Elisa Vazquez-Liebanas, Khayrun Nahar, Bongnam Jung, Xidan Li, Bryan C. Tan, Juat Chin Foo, Amaury Cazenave-Gassiot, Markus R. Wenk, Yvette Zarb, Barbara Lavina, Susan E. Quaggin, Marie Jeansson, Chengua Gu, David L. Silver, Michael Vanlandewijck, Eugene C. Butcher, Annika Keller, Christer Betsholtz

Circ Res. Author manuscript; available in PMC 2024 Feb 10.

Published in final edited form as: Circ Res. 2021 Feb 19; 128(4): e46–e62. Published online 2020 Dec 30. doi: 10.1161/CIRCRESAHA.120.317473

PMCID:: PMC10858745

Abstract Article PDF–2.1M

Select item 106453752.

Breaking the feed forward inflammatory cytokine loop in the tumor microenvironment of PDGFB-driven glioblastomas

C. Ryan Miller, Anita B. Hjelmeland

J Clin Invest. 2023 Nov 15; 133(22): e175127. Published online 2023 Nov 15. doi: 10.1172/JCI175127

PMCID:: PMC10645375

Abstract Article PDF–678K

Select item 103693013.

Elevated PDGF‐BB from Bone Impairs Hippocampal Vasculature by Inducing PDGFRβ Shedding from Pericytes

Guanqiao Liu, Jiekang Wang, Zhiliang Wei, Ching‐Lien Fang, Ke Shen, Cheng Qian, Cheng Qi, Tong Li, Peisong Gao, Philip C. Wong, Hanzhang Lu, Xu Cao, Mei Wan

Adv Sci (Weinh) 2023 Jul; 10(20): 2206938. Published online 2023 Apr 27. doi: 10.1002/advs.202206938

PMCID:: PMC10369301

Abstract Article PDF–11M

Select item 102596684.

Perivascular localized cells commit erythropoiesis in PDGF‐B‐expressing solid tumors

Kayoko Hosaka, Chenchen Wang, Shiyue Zhang, Xue Lv, Takahiro Seki, Yin Zhang, Xu Jing, Jieyu Wu, Qiqiao Du, Xingkang He, Yulong Fan, Xuan Li, Makoto Kondo, Masahito Yoshihara, Hong Qian, Lihong Shi, Ping Zhu, Yuanfu Xu, Yunlong Yang, Tao Cheng, Yihai Cao

Cancer Commun (Lond) 2023 Jun; 43(6): 637–660. Published online 2023 Apr 29. doi: 10.1002/cac2.12423

PMCID:: PMC10259668

Abstract Article PDF–8.4M

Select item 101081845.

Altered hemodynamics and vascular reactivity in a mouse model with severe pericyte deficiency

Jillian L Stobart, Eva Erlebach, Chaim Glück, Sheng-Fu Huang, Matthew JP Barrett, Max Li, Sergei A Vinogradov, Jan Klohs, Yvette Zarb, Annika Keller, Bruno Weber

J Cereb Blood Flow Metab. 2023 May; 43(5): 763–777. Published online 2022 Dec 22. doi: 10.1177/0271678X221147366

PMCID:: PMC10108184

Abstract Article PDF–1.8M

Select item 101030896.

The Role of Platelet-Derived Growth Factor in Focal Segmental Glomerulosclerosis

Ting Jia, Tong Xu, Bart Smeets, Eva Miriam Buhl, Marcus Johannes Moeller, Jürgen Floege, Barbara Mara Klinkhammer, Peter Boor

J Am Soc Nephrol. 2023 Feb; 34(2): 241–257. Published online 2022 Nov 9. doi: 10.1681/ASN.2022040491

PMCID:: PMC10103089

Abstract Article

Select item 97137167.

Maternal immune activation leads to defective brain–blood vessels and intracerebral hemorrhages in male offspring

Marco Rasile, Eliana Lauranzano, Elisa Faggiani, Margherita M Ravanelli, Federico S Colombo, Filippo Mirabella, Irene Corradini, Maria L Malosio, Antonella Borreca, Elisa Focchi, Davide Pozzi, Toni Giorgino, Isabella Barajon, Michela Matteoli

EMBO J. 2022 Dec; 41(23): e111192. Published online 2022 Oct 31. doi: 10.15252/embj.2022111192

Correction in:: EMBO J. 2023 May; 42(10): e113890.

PMCID:: PMC9713716

Abstract Article PDF–3.2M

Select item 94214008.

Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development

Linh T. Trinh, Anna B. Osipovich, Leesa Sampson, Jonathan Wong, Chris V.E. Wright, Mark A. Magnuson

iScience. 2022 Sep 16; 25(9): 104905. Published online 2022 Aug 11. doi: 10.1016/j.isci.2022.104905

PMCID:: PMC9421400

Abstract Article PDF–4.7M

Select item 92794149.

A SOX17-PDGFB signaling axis regulates aortic root development

Pengfei Lu, Ping Wang, Bingruo Wu, Yidong Wang, Yang Liu, Wei Cheng, Xuhui Feng, Xinchun Yuan, Miriam M. Atteya, Haleigh Ferro, Yukiko Sugi, Grant Rydquist, Mahdi Esmaily, Jonathan T. Butcher, Ching-Pin Chang, Jack Lenz, Deyou Zheng, Bin Zhou

Nat Commun. 2022; 13: 4065. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31815-1

PMCID:: PMC9279414

Abstract Article PDF–11M

Select item 902490610.

Platelet-Derived PDGFB Promotes Recruitment of Cancer-Associated Fibroblasts, Deposition of Extracellular Matrix and Tgfβ Signaling in the Tumor Microenvironment

Yanyu Zhang, Ehsan Manouchehri Doulabi, Melanie Herre, Jessica Cedervall, Qi Qiao, Zuoxiu Miao, Anahita Hamidi, Lars Hellman, Masood Kamali-Moghaddam, Anna-Karin Olsson

Cancers (Basel) 2022 Apr; 14(8): 1947. Published online 2022 Apr 12. doi: 10.3390/cancers14081947

PMCID:: PMC9024906

Abstract Article PDF–27M

Select item 879521811.

Adult-induced genetic ablation distinguishes PDGFB roles in blood-brain barrier maintenance and development

Elisa Vazquez-Liebanas, Khayrun Nahar, Giacomo Bertuzzi, Annika Keller, Christer Betsholtz, Maarja Andaloussi Mäe

J Cereb Blood Flow Metab. 2022 Feb; 42(2): 264–279. Published online 2021 Oct 25. doi: 10.1177/0271678X211056395

PMCID:: PMC8795218

Abstract Article PDF–2.7M

Select item 861645312.

Regulation of Transplanted Cell Homing by FGF1 and PDGFB after Doxorubicin Myocardial Injury

Mark Baguma-Nibasheka, Tiam Feridooni, Feixiong Zhang, Kishore B.S. Pasumarthi

Cells. 2021 Nov; 10(11): 2998. Published online 2021 Nov 3. doi: 10.3390/cells10112998

PMCID:: PMC8616453

Abstract Article PDF–3.3M

Select item 855468213.

Glucocorticoids Disrupt Skeletal Angiogenesis Through Transrepression of NF-κB–Mediated Preosteoclast Pdgfb Transcription in Young Mice

Yi Peng, Shan Lv, Yusheng Li, Jianxi Zhu, Shijie Chen, Gehua Zhen, Xu Cao, Song Wu, Janet L. Crane

J Bone Miner Res. Author manuscript; available in PMC 2021 Oct 29.

Published in final edited form as: J Bone Miner Res. 2020 Jun; 35(6): 1188–1202. Published online 2020 Mar 11. doi: 10.1002/jbmr.3987

PMCID:: PMC8554682

Abstract Article PDF–2.7M

Select item 855385714.

Quantitative 3D imaging of the cranial microvascular environment at single-cell resolution

Alexandra N. Rindone, Xiaonan Liu, Stephanie Farhat, Alexander Perdomo-Pantoja, Timothy F. Witham, Daniel L. Coutu, Mei Wan, Warren L. Grayson

Nat Commun. 2021; 12: 6219. Published online 2021 Oct 28. doi: 10.1038/s41467-021-26455-w

PMCID:: PMC8553857

Abstract Article PDF–8.5M

Select item 795824715.

Pericytes regulate vascular immune homeostasis in the CNS

Orsolya Török, Bettina Schreiner, Johanna Schaffenrath, Hsing-Chuan Tsai, Upasana Maheshwari, Sebastian A. Stifter, Christina Welsh, Ana Amorim, Sucheta Sridhar, Sebastian G. Utz, Wiebke Mildenberger, Sina Nassiri, Mauro Delorenzi, Adriano Aguzzi, May H. Han, Melanie Greter, Burkhard Becher, Annika Keller

Proc Natl Acad Sci U S A. 2021 Mar 9; 118(10): e2016587118. Published online 2021 Mar 2. doi: 10.1073/pnas.2016587118

PMCID:: PMC7958247

Abstract Article PDF–4.2M

Select item 790987916.

Microglia control small vessel calcification via TREM2

Yvette Zarb, Sucheta Sridhar, Sina Nassiri, Sebastian Guido Utz, Johanna Schaffenrath, Upasana Maheshwari, Elisabeth J. Rushing, K. Peter R. Nilsson, Mauro Delorenzi, Marco Colonna, Melanie Greter, Annika Keller

Sci Adv. 2021 Feb; 7(9): eabc4898. Published online 2021 Feb 26. doi: 10.1126/sciadv.abc4898

PMCID:: PMC7909879

Abstract Article PDF–4.7M

Select item 765391117.

Genetic analyses in mouse fibroblast and melanoma cells demonstrate novel roles for PDGF-AB ligand and PDGF receptor alpha

Julie L. Kadrmas, Mary C. Beckerle, Masaaki Yoshigi

Sci Rep. 2020; 10: 19303. Published online 2020 Nov 9. doi: 10.1038/s41598-020-75774-3

PMCID:: PMC7653911

Abstract Article PDF–5.2M

Select item 741459618.

Hepatic transferrin plays a role in systemic iron homeostasis and liver ferroptosis

Yingying Yu, Li Jiang, Hao Wang, Zhe Shen, Qi Cheng, Pan Zhang, Jiaming Wang, Qian Wu, Xuexian Fang, Lingyan Duan, Shufen Wang, Kai Wang, Peng An, Tuo Shao, Raymond T. Chung, Shusen Zheng, Junxia Min, Fudi Wang

Blood. 2020 Aug 6; 136(6): 726–739. Prepublished online 2020 May 6. doi: 10.1182/blood.2019002907

PMCID:: PMC7414596

Abstract Article

Select item 731759919.

Astrocyte–microglial association and matrix composition are common events in the natural history of primary familial brain calcification

Khayrun Nahar, Thibaud Lebouvier, Maarja Andaloussi Mäe, Anne Konzer, Jonas Bergquist, Yvette Zarb, Bengt Johansson, Christer Betsholtz, Michael Vanlandewijck

Brain Pathol. 2020 May; 30(3): 446–464. Published online 2019 Oct 10. doi: 10.1111/bpa.12787

PMCID:: PMC7317599

Abstract Article PDF–3.9M

Select item 730569220.

A systems genetics approach to revealing the Pdgfb molecular network of the retina

Shasha Li, Fuyi Xu, Lin Liu, Rong Ju, Jonas Bergquist, Qing Yin Zheng, Jia Mi, Lu Lu, Xuri Li, Geng Tian

Mol Vis. 2020; 26: 459–471. Published online 2020 Jun 19.

PMCID:: PMC7305692

Abstract Article PDF–3.0M

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