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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 105775532.

Downregulation of Krüppel‐like factor 14 accelerated cellular senescence and aging

Yuli Hou, Qiao Song, Yaqi Wang, Jing Liu, Yuting Cui, Xiaomin Zhang, Jingjing Zhang, Jingxuan Fu, Min Cao, Chi Zhang, Congcong Liu, Xiaoling Wang, Huanli Duan, Peichang Wang

Aging Cell. 2023 Oct; 22(10): e13950. Published online 2023 Aug 8. doi: 10.1111/acel.13950

PMCID:: PMC10577553

Abstract Article PDF–18M

Select item 89760553.

The transcription factor KLF14 regulates macrophage glycolysis and immune function by inhibiting HK2 in sepsis

Yuan Yuan, Guangjian Fan, Yuqi Liu, Lu Liu, Tong Zhang, Pengfei Liu, Qing Tu, Xinyi Zhang, Shiyuan Luo, Liangfang Yao, Feng Chen, Jingbao Li

Cell Mol Immunol. 2022 Apr; 19(4): 504–515. Published online 2022 Jan 4. doi: 10.1038/s41423-021-00806-5

Correction in:: Cell Mol Immunol. 2022 May; 19(5): 650.

PMCID:: PMC8976055

Abstract Article PDF–4.9M

Select item 89656854.

Adipocyte-Specific Modulation of KLF14 Expression in Mice Leads to Sex-Dependent Impacts on Adiposity and Lipid Metabolism

Qianyi Yang, Jameson Hinkle, Jordan N. Reed, Redouane Aherrahrou, Zhiwen Xu, Thurl E. Harris, Erin J. Stephenson, Kiran Musunuru, Susanna R. Keller, Mete Civelek

Diabetes. 2022 Apr; 71(4): 677–693. Published online 2022 Jan 26. doi: 10.2337/db21-0674

PMCID:: PMC8965685

Abstract Article PDF–35M

Select item 88030765.

Krüppel-like factor 14 deletion in myeloid cells accelerates atherosclerotic lesion development

Huilun Wang, Yanhong Guo, Haocheng Lu, Yonghong Luo, Wenting Hu, Wenying Liang, Minerva T Garcia-Barrio, Lin Chang, Anna Schwendeman, Jifeng Zhang, Y Eugene Chen

Cardiovasc Res. 2022 Feb; 118(2): 475–488. Published online 2021 Feb 4. doi: 10.1093/cvr/cvab027

PMCID:: PMC8803076

Abstract Article PDF–2.1M

Select item 86073546.

Germline deletion of Krüppel-like factor 14 does not increase risk of diet induced metabolic syndrome in male C57BL/6 mice

Carmen A. Argmann, Sara Violante, Tetyana Dodatko, Mariana P. Amaro, Jacob Hagen, Virginia L. Gillespie, Christoph Buettner, Eric E. Schadt, Sander M. Houten

Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2021 Nov 22.

Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2017 Dec; 1863(12): 3277–3285. Published online 2017 Sep 28. doi: 10.1016/j.bbadis.2017.09.021

PMCID:: PMC8607354

Abstract Article PDF–1.5M

Select item 77740947.

Klf14 is an imprinted transcription factor that regulates placental growth

Erik Koppes, Ben Shaffer, Elena Sadovsky, Katherine Himes, Yaacov Barak, Yoel Sadovsky, J. Richard Chaillet

Placenta. Author manuscript; available in PMC 2020 Dec 31.

Published in final edited form as: Placenta. 2019 Dec; 88: 61–67. Published online 2019 Sep 27. doi: 10.1016/j.placenta.2019.09.013

PMCID:: PMC7774094

Abstract Article PDF–834K

Select item 64412798.

Krüppel-like factor 14, a coronary artery disease associated transcription factor, inhibits endothelial inflammation via NF-κB signaling pathway

Wenting Hu, Haocheng Lu, Jifeng Zhang, Yanbo Fan, Ziyi Chang, Wenying Liang, Huilun Wang, Tianqing Zhu, Minerva T. Garcia-Barrio, Daoquan Peng, Y. Eugene Chen, Yanhong Guo

Atherosclerosis. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Atherosclerosis. 2018 Nov; 278: 39–48. Published online 2018 Sep 15. doi: 10.1016/j.atherosclerosis.2018.09.018

PMCID:: PMC6441279

Abstract Article PDF–1.8M

Select item 59352359.

Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition

Kerrin S. Small, Marijana Todorcevic, Mete Civelek, Julia S. El-Sayed Moustafa, Xiao Wang, Michelle M. Simon, Juan Fernandez-Tajes, Anubha Mahajan, Momoko Horikoshi, Alison Hugill, Craig A. Glastonbury, Lydia Quaye, Matt J. Neville, Siddharth Sethi, Marianne Yon, Calvin Pan, Nam Che, Ana Viñuela, Pei-Chien Tsai, Abhishek Nag, Alfonso Buil, Gudmar Thorleifsson, Avanthi Raghavan, Qiurong Ding, Andrew P. Morris, Jordana T. Bell, Unnur Thorsteinsdottir, Kari Stefansson, Markku Laakso, Ingrid Dahlman, Peter Arner, Anna L. Gloyn, Kiran Musunuru, Aldons J. Lusis, Roger Cox, Fredrik Karpe, Mark I. McCarthy

Nat Genet. Author manuscript; available in PMC 2018 Oct 9.

Published in final edited form as: Nat Genet. 2018 Apr; 50(4): 572–580. Published online 2018 Apr 9. doi: 10.1038/s41588-018-0088-x

Correction in:: Nat Genet. 2018 Aug 7

PMCID:: PMC5935235

Abstract Article PDF–2.2M

Select item 529582110.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 473971911.

Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression

David B. West, Eric K. Engelhard, Michael Adkisson, A. J. Nava, Julia V. Kirov, Andreanna Cipollone, Brandon Willis, Jared Rapp, Pieter J. de Jong, Kent C. Lloyd

PLoS Genet. 2016 Feb; 12(2): e1005691. Published online 2016 Feb 3. doi: 10.1371/journal.pgen.1005691

PMCID:: PMC4739719

Abstract Article PDF–1.5M

Select item 460713712.

Perhexiline activates KLF14 and reduces atherosclerosis by modulating ApoA-I production

Yanhong Guo, Yanbo Fan, Jifeng Zhang, Gwen A. Lomberk, Zhou Zhou, Lijie Sun, Angela J. Mathison, Minerva T. Garcia-Barrio, Ji Zhang, Lixia Zeng, Lei Li, Subramaniam Pennathur, Cristen J. Willer, Daniel J. Rader, Raul Urrutia, Y. Eugene Chen

J Clin Invest. 2015 Oct 1; 125(10): 3819–3830. Published online 2015 Sep 14. doi: 10.1172/JCI79048

PMCID:: PMC4607137

Abstract Article PDF–1.7M

Select item 460075413.

Loss of KLF14 triggers centrosome amplification and tumorigenesis

Guangjian Fan, Lianhui Sun, Peipei Shan, Xianying Zhang, Jinliang Huan, Xiaohong Zhang, Dali Li, Tingting Wang, Tingting Wei, Xiaohong Zhang, Xiaoyang Gu, Liangfang Yao, Yang Xuan, Zhaoyuan Hou, Yongping Cui, Liu Cao, Xiaotao Li, Shengping Zhang, Chuangui Wang

Nat Commun. 2015; 6: 8450. Published online 2015 Oct 6. doi: 10.1038/ncomms9450

PMCID:: PMC4600754

Abstract Article PDF–1.9M

Select item 414093414.

New Role for Kruppel-like Factor 14 as a Transcriptional Activator Involved in the Generation of Signaling Lipids

Thiago M. de Assuncao, Gwen Lomberk, Sheng Cao, Usman Yaqoob, Angela Mathison, Douglas A. Simonetto, Robert C. Huebert, Raul A. Urrutia, Vijay H. Shah

J Biol Chem. 2014 May 30; 289(22): 15798–15809. Published online 2014 Apr 23. doi: 10.1074/jbc.M113.544346

PMCID:: PMC4140934

Abstract Article PDF–2.3M

Select item 396495515.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 350814016.

Generalized disruption of inherited genomic imprints leads to wide-ranging placental defects and dysregulated fetal growth

K. P. Himes, E. Koppes, J. Richard Chaillet

Dev Biol. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Dev Biol. 2013 Jan 1; 373(1): 72–82. Published online 2012 Oct 17. doi: 10.1016/j.ydbio.2012.10.010

PMCID:: PMC3508140

Abstract Article PDF–7.3M

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253418.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 186556119.

Identification of the Imprinted KLF14 Transcription Factor Undergoing Human-Specific Accelerated Evolution

Layla Parker-Katiraee, Andrew R Carson, Takahiro Yamada, Philippe Arnaud, Robert Feil, Sayeda N Abu-Amero, Gudrun E Moore, Masahiro Kaneda, George H Perry, Anne C Stone, Charles Lee, Makiko Meguro-Horike, Hiroyuki Sasaki, Keiko Kobayashi, Kazuhiko Nakabayashi, Stephen W Scherer

PLoS Genet. 2007 May; 3(5): e65. Prepublished online 2007 Mar 12. Published online 2007 May 4. doi: 10.1371/journal.pgen.0030065

PMCID:: PMC1865561

Abstract Article PDF–880K

Select item 31099220.

RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer

Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki

Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600