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Select item 111997101.

IGFBP2/ITGA5 promotes gefitinib resistance via activating STAT3/CXCL1 axis in non-small cell lung cancer

Hengxiao Lu, Jiangshan Ai, Yingying Zheng, Wolong Zhou, Liming Zhang, Jiebo Zhu, Heng Zhang, Shaoqiang Wang

Cell Death Dis. 2024 Jun; 15(6): 447. Published online 2024 Jun 25. doi: 10.1038/s41419-024-06843-y

PMCID:: PMC11199710

Abstract Article PDF–10M

Select item 110288132.

Integrin alphavbeta6 promotes tumor tolerance in colorectal cancer

Shao-Bo Yang, Yun Du, Ben-Yan Wu, Shi-Ping Xu, Jun-Bao Wen, Min Zhu, Chang-Hao Cai, Ping-Chang Yang

Cancer Immunol Immunother. 2012 Mar; 61(3): 335–342. Published online 2011 Sep 13. doi: 10.1007/s00262-011-1108-1

PMCID:: PMC11028813

Abstract Article PDF–396K

Select item 108365733.

A Continuous Extension of Gene Set Enrichment Analysis Using the Likelihood Ratio Test Statistics Identifies Vascular Endothelial Growth Factor as a Candidate Pathway for Alzheimer’s Disease via ITGA5

Ali Mahzarnia, Michael W. Lutz, Alexandra Badea

J Alzheimers Dis. 2024; 97(2): 635–648. Prepublished online 2023 Dec 23. Published online 2024 Jan 16. doi: 10.3233/JAD-230934

PMCID:: PMC10836573

Abstract Article PDF–1.2M

Select item 107652214.

Aldo-keto Reductase 1B10 Restrains Cell Migration, Invasion, and Adhesion of Gastric Cancer via Regulating Integrin Subunit Alpha 5

Haibo Yao, Junfeng Hu, Yanfei Shao, Qinshu Shao, Shusen Zheng

Turk J Gastroenterol. 2023 Dec; 34(12): 1197–1205. Published online 2023 Dec 1. doi: 10.5152/tjg.2023.22555

PMCID:: PMC10765221

Abstract Article PDF–3.6M

Select item 102423425.

ITGA5 promotes tumor angiogenesis in cervical cancer

Xiaohan Xu, Lulu Shen, Wenhan Li, Xiaoli Liu, Ping Yang, Jing Cai

Cancer Med. 2023 May; 12(10): 11983–11999. Published online 2023 Mar 31. doi: 10.1002/cam4.5873

PMCID:: PMC10242342

Abstract Article PDF–14M

Select item 102374226.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101307487.

The C-type lectin domain of CD62P (P-selectin) functions as an integrin ligand

Yoko K Takada, Scott I Simon, Yoshikazu Takada

Life Sci Alliance. 2023 Jul; 6(7): e202201747. Published online 2023 Apr 25. doi: 10.26508/lsa.202201747

PMCID:: PMC10130748

Abstract Article PDF–3.6M

Select item 99391398.

ITGA5 and ITGB1 contribute to Sorafenib resistance by promoting vasculogenic mimicry formation in hepatocellular carcinoma

Ying Shi, Jin Shang, Yan Li, Deyuan Zhong, Zilong Zhang, Qinyan Yang, Chunyou Lai, Tianhang Feng, Yutong Yao, Xiaolun Huang

Cancer Med. 2023 Feb; 12(3): 3786–3796. Published online 2022 Aug 10. doi: 10.1002/cam4.5110

PMCID:: PMC9939139

Abstract Article PDF–12M

Select item 99126489.

The members of the miR-148/152 family inhibit cancer stem cell-like properties in gastric cancer via negative regulation of ITGA5

Xiaoying Li, Lin Li, Jiangying Wu

J Transl Med. 2023; 21: 105. Published online 2023 Feb 10. doi: 10.1186/s12967-023-03894-1

PMCID:: PMC9912648

Abstract Article PDF–1.8M

Select item 983529610.

AFAP1L1 promotes gastric cancer progression by interacting with VAV2 to facilitate CDC42-mediated activation of ITGA5 signaling pathway

Bo Sun, Bai Ding, Yu Chen, Chuang Peng, Xu Chen

J Transl Med. 2023; 21: 18. Published online 2023 Jan 11. doi: 10.1186/s12967-023-03871-8

PMCID:: PMC9835296

Abstract Article PDF–23M

Select item 969135811.

Elevated ITGA5 facilitates hyperactivated mTORC1-mediated progression of laryngeal squamous cell carcinoma via upregulation of EFNB2

Dapeng Li, Anjiang Sun, Liang Zhang, Zhao Ding, Fangzheng Yi, Xue Yang, Zixi Wang, Xu Chen, Weiwei Liu, Shixian Liu, Hailong Shen, Manli Miao, Ling Zhang, Ping Liu, Yuchen Liu, Shihong Su, Hailiang Huang, Can Huang, Zhongdong Hu, Hongbing Zhang, Xiaojun Zha, Yehai Liu

Theranostics. 2022; 12(17): 7431–7449. Published online 2022 Oct 24. doi: 10.7150/thno.76232

PMCID:: PMC9691358

Abstract Article PDF–5.4M

Select item 952661812.

ITGA5 Promotes Tumor Progression through the Activation of the FAK/AKT Signaling Pathway in Human Gastric Cancer

Jun-fu Wang, Ye-yang Chen, Si-wen Zhang, Kun Zhao, Yue Qiu, Ye Wang, Jian-cheng Wang, Zhu Yu, Bo-pei Li, Zheng Wang, Jun-qiang Chen

Oxid Med Cell Longev. 2022; 2022: 8611306. Published online 2022 Sep 24. doi: 10.1155/2022/8611306

PMCID:: PMC9526618

Abstract Article PDF–2.7M

Select item 938962613.

Targeting HIF1-alpha/miR-326/ITGA5 axis potentiates chemotherapy response in triple-negative breast cancer

Ridho Assidicky, Unal Metin Tokat, Ibrahim Oguzhan Tarman, Ozge Saatci, Pelin Gulizar Ersan, Umar Raza, Hasan Ogul, Yasser Riazalhosseini, Tolga Can, Ozgur Sahin

Breast Cancer Res Treat. Author manuscript; available in PMC 2022 Aug 19.

Published in final edited form as: Breast Cancer Res Treat. 2022 Jun; 193(2): 331–348. Published online 2022 Mar 25. doi: 10.1007/s10549-022-06569-5

PMCID:: PMC9389626

Abstract Article PDF–2.2M

Select item 926261414.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 923162315.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 903755416.

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy

Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell

Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116

PMCID:: PMC9037554

Abstract Article PDF–4.1M

Select item 849735417.

LncRNA NEAT1 Enhances Glioma Progression via Regulating the miR-128-3p/ITGA5 Axis

Jiakai Chen, Handong Wang, Junjun Wang, Wenhao Niu, Chulei Deng, Mengliang Zhou

Mol Neurobiol. 2021; 58(10): 5163–5177. Published online 2021 Jul 15. doi: 10.1007/s12035-021-02474-y

PMCID:: PMC8497354

Abstract Article PDF–7.7M

Select item 847109818.

Cellular Integrin α5β1 and Exosomal ADAM17 Mediate the Binding and Uptake of Exosomes Produced by Colorectal Carcinoma Cells

Beatriz Cardeñes, Irene Clares, Víctor Toribio, Lucía Pascual, Soraya López-Martín, Alvaro Torres-Gomez, Ricardo Sainz de la Cuesta, Esther M. Lafuente, Manuel López-Cabrera, María Yáñez-Mó, Carlos Cabañas

Int J Mol Sci. 2021 Sep; 22(18): 9938. Published online 2021 Sep 14. doi: 10.3390/ijms22189938