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Items: 1 to 20 of 101

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis
Pengfei Guo, Rebecca C Lim, Keshari Rajawasam, Tiffany Trinh, Hong Sun, Hui Zhang
eLife. 2024; 13: e86168. Published online 2024 Feb 12. doi: 10.7554/eLife.86168
PMCID:
PMC10901513
AbstractArticlePDF–9.2M
3.
Biglycan regulated colorectal cancer progress by modulating enteric neuron-derived IL-10 and abundance of Bacteroides thetaiotaomicron
Yuyu Xu, Fei Wang, Kai Mi, Xinyuan Wang, Danlei Wang, Qing Zhao, Jingjing Wang, Zhi Liu, Qingqing Zhang, Yang Liu, Xuemei Zhang, Xingyin Liu
iScience. 2023 Sep 15; 26(9): 107515. Published online 2023 Aug 2. doi: 10.1016/j.isci.2023.107515
PMCID:
PMC10469580
AbstractArticlePDF–6.1M
4.
Toll-like receptor 3 mediates aortic stenosis via a conserved mechanism of calcification
Can Gollmann-Tepeköylü, Michael Graber, Jakob Hirsch, Sophia Mair, Andreas Naschberger, Leo Pölzl, Felix Nägele, Elke Kirchmair, Gerald Degenhart, Egon Demetz, Richard Hilbe, Hao-Yu Chen, James C. Engert, Anna Böhm, Nadja Franz, Daniela Lobenwein, Daniela Lener, Christiane Fuchs, Anna Weihs, Sonja Töchterle, Georg F. Vogel, Victor Schweiger, Jonas Eder, Peter Pietschmann, Markus Seifert, Florian Kronenberg, Stefan Coassin, Michael Blumer, Hubert Hackl, Dirk Meyer, Gudrun Feuchtner, Rudolf Kirchmair, Jakob Troppmair, Markus Krane, Günther Weiss, Sotirios Tsimikas, George Thanassoulis, Michael Grimm, Bernhard Rupp, Lukas A. Huber, Shen-Ying Zhang, Jean-Laurent Casanova, Ivan Tancevski, Johannes Holfeld
Circulation. Author manuscript; available in PMC 2024 May 16.
Published in final edited form as: Circulation. 2023 May 16; 147(20): 1518–1533. Published online 2023 Apr 4. doi: 10.1161/CIRCULATIONAHA.122.063481
PMCID:
PMC10192061
AbstractArticlePDF–3.0M
5.
Biglycan regulates bone development and regeneration
Reut Shainer, Vardit Kram, Tina M. Kilts, Li Li, Andrew D. Doyle, Inbal Shainer, Daniel Martin, Carl G. Simon, Jr., Jinyang Zeng-Brouwers, Liliana Schaefer, Marian F. Young, Genomics and Computational Biology Core
Front Physiol. 2023; 14: 1119368. Published online 2023 Feb 16. doi: 10.3389/fphys.2023.1119368
PMCID:
PMC9979216
AbstractArticlePDF–4.5M
6.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
7.
Inhibition of stromal biglycan promotes normalization of the tumor microenvironment and enhances chemotherapeutic efficacy
Li Cong, Nako Maishi, Dorcas A. Annan, Marian F. Young, Hirofumi Morimoto, Masahiro Morimoto, Jin-Min Nam, Yasuhiro Hida, Kyoko Hida
Breast Cancer Res. 2021; 23: 51. Published online 2021 May 10. doi: 10.1186/s13058-021-01423-w
PMCID:
PMC8108358
AbstractArticlePDF–3.4M
8.
Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease
Scott E. Youlten, John P. Kemp, John G. Logan, Elena J. Ghirardello, Claudio M. Sergio, Michael R. G. Dack, Siobhan E. Guilfoyle, Victoria D. Leitch, Natalie C. Butterfield, Davide Komla-Ebri, Ryan C. Chai, Alexander P. Corr, James T. Smith, Sindhu T. Mohanty, John A. Morris, Michelle M. McDonald, Julian M. W. Quinn, Amelia R. McGlade, Nenad Bartonicek, Matt Jansson, Konstantinos Hatzikotoulas, Melita D. Irving, Ana Beleza-Meireles, Fernando Rivadeneira, Emma Duncan, J. Brent Richards, David J. Adams, Christopher J. Lelliott, Robert Brink, Tri Giang Phan, John A. Eisman, David M. Evans, Eleftheria Zeggini, Paul A. Baldock, J. H. Duncan Bassett, Graham R. Williams, Peter I. Croucher
Nat Commun. 2021; 12: 2444. Published online 2021 May 5. doi: 10.1038/s41467-021-22517-1
PMCID:
PMC8100170
AbstractArticlePDF–11M
9.
Transcriptomic profiling of fetal membranes of mice deficient in biglycan and decorin as a model of preterm birth
Priyadarshini Pantham, Don L Armstrong, Jonathan Bodnariuc, Owen Haupt, Amy Wagoner Johnson, Lori Underhill, Renato V Iozzo, Beatrice E Lechner, Derek E Wildman
Biol Reprod. 2021 Mar; 104(3): 611–623. Published online 2020 Nov 9. doi: 10.1093/biolre/ioaa205
PMCID:
PMC7962763
AbstractArticlePDF–443K
10.
OPG-Fc treatment partially rescues low bone mass phenotype in mature Bgn/Fmod deficient mice but is deleterious to the young mouse skeleton
Vardit Kram, Priyam Jani, Tina M. Kilts, Li Li, Emily Y. Chu, Marian F. Young
J Struct Biol. Author manuscript; available in PMC 2021 Dec 1.
Published in final edited form as: J Struct Biol. 2020 Dec 1; 212(3): 107627. Published online 2020 Sep 17. doi: 10.1016/j.jsb.2020.107627
PMCID:
PMC7744403
AbstractArticlePDF–2.3M
11.
Biglycan and chondroitin sulfate play pivotal roles in bone toughness via retaining bound water in bone mineral matrix
Rui Hua, Qingwen Ni, Travis D. Eliason, Yan Han, Sumin Gu, Daniel P. Nicolella, Xiaodu Wang, Jean X. Jiang
Matrix Biol. Author manuscript; available in PMC 2020 Dec 8.
Published in final edited form as: Matrix Biol. 2020 Dec; 94: 95–109. Published online 2020 Sep 28. doi: 10.1016/j.matbio.2020.09.002
PMCID:
PMC7722036
AbstractArticlePDF–1.6M
12.
Serum amyloid A–containing HDL binds adipocyte-derived versican and macrophage-derived biglycan, reducing its antiinflammatory properties
Chang Yeop Han, Inkyung Kang, Mohamed Omer, Shari Wang, Tomasz Wietecha, Thomas N. Wight, Alan Chait
JCI Insight. 2020 Oct 15; 5(20): e142635. Published online 2020 Sep 24. doi: 10.1172/jci.insight.142635
PMCID:
PMC7605543
AbstractArticlePDF–7.4M
13.
Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity
Chang Yeop Han, Inkyung Kang, Ingrid A. Harten, John A. Gebe, Christina K. Chan, Mohamed Omer, Kimberly M. Alonge, Laura J. den Hartigh, Diego Gomes Kjerulf, Leela Goodspeed, Savitha Subramanian, Shari Wang, Francis Kim, David E. Birk, Thomas N. Wight, Alan Chait
Cell Rep. Author manuscript; available in PMC 2020 Jul 27.
Published in final edited form as: Cell Rep. 2020 Jun 30; 31(13): 107818. doi: 10.1016/j.celrep.2020.107818
PMCID:
PMC7384517
AbstractArticlePDF–2.1M
14.
The Spatiotemporal Expression Pattern of Syndecans in Murine Embryonic Teeth
Jingyi Wu, Hong Li, Lu Han, Tianyu Sun, Ye Tian, Xiaofang Wang
Gene Expr Patterns. Author manuscript; available in PMC 2021 Jun 1.
Published in final edited form as: Gene Expr Patterns. 2020 Jun; 36: 119109. Published online 2020 Mar 24. doi: 10.1016/j.gep.2020.119109
PMCID:
PMC7293924
AbstractArticlePDF–1.2M
15.
Bimodal role of NADPH oxidases in the regulation of biglycan-triggered IL-1β synthesis
Louise Tzung-Harn Hsieh, Helena Frey, Madalina-Viviana Nastase, Claudia Tredup, Adrian Hoffmann, Chiara Poluzzi, Jinyang Zeng-Brouwers, Tina Manon-Jensen, Katrin Schröder, Ralf P. Brandes, Renato V. Iozzo, Liliana Schaefer
Matrix Biol. Author manuscript; available in PMC 2020 Jan 10.
Published in final edited form as: Matrix Biol. 2016 Jan; 49: 61–81. Published online 2015 Dec 12. doi: 10.1016/j.matbio.2015.12.005
PMCID:
PMC6953411
AbstractArticlePDF–2.6M
16.
Regulation of pre‐adipocyte proliferation and apoptosis by the small leucine‐rich proteoglycans, biglycan and decorin
M. Ward, K. M. Ajuwon
Cell Prolif. 2011 Aug; 44(4): 343–351. Published online 2011 Jun 27. doi: 10.1111/j.1365-2184.2011.00763.x
PMCID:
PMC6496550
AbstractArticlePDF–703K
17.
Biglycan gene connects metabolic dysfunction with brain disorder
Zhe Ying, Hyae Ran Byun, Qingying Meng, Emily Noble, Guanglin Zhang, Xia Yang, Fernando Gomez-Pinilla
Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2018 Dec 1.
Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2018 Dec; 1864(12): 3679–3687. Published online 2018 Oct 3. doi: 10.1016/j.bbadis.2018.10.002
PMCID:
PMC6239930
AbstractArticlePDF–1.8M
18.
The metalloproteinase-proteoglycans ADAMTS7 and ADAMTS12 provide an innate, tendon-specific protective mechanism against heterotopic ossification
Timothy J. Mead, Daniel R. McCulloch, Jason C. Ho, Yaoyao Du, Sheila M. Adams, David E. Birk, Suneel S. Apte
JCI Insight. 2018 Apr 5; 3(7): e92941. Published online 2018 Apr 5. doi: 10.1172/jci.insight.92941
PMCID:
PMC5928868
AbstractArticlePDF–3.2M
19.
Impaired proteoglycan glycosylation, elevated TGF-β signaling, and abnormal osteoblast differentiation as the basis for bone fragility in a mouse model for gerodermia osteodysplastica
Wing Lee Chan, Magdalena Steiner, Tomasz Witkos, Johannes Egerer, Björn Busse, Shuji Mizumoto, Jan M. Pestka, Haikuo Zhang, Ingrid Hausser, Layal Abo Khayal, Claus-Eric Ott, Mateusz Kolanczyk, Bettina Willie, Thorsten Schinke, Chiara Paganini, Antonio Rossi, Kazuyuki Sugahara, Michael Amling, Petra Knaus, Danny Chan, Martin Lowe, Stefan Mundlos, Uwe Kornak
PLoS Genet. 2018 Mar; 14(3): e1007242. Published online 2018 Mar 21. doi: 10.1371/journal.pgen.1007242
PMCID:
PMC5880397
AbstractArticlePDF–10M
20.
Elevated circulating TGF-β is not the cause of increased atherosclerosis development in biglycan deficient mice
Joel C. Thompson, Patricia G. Wilson, Alex P. Wyllie, Adrian K. Wyllie, Lisa R. Tannock
Atherosclerosis. Author manuscript; available in PMC 2019 Jan 1.
Published in final edited form as: Atherosclerosis. 2018 Jan; 268: 68–75. Published online 2017 Nov 10. doi: 10.1016/j.atherosclerosis.2017.11.005
PMCID:
PMC5750111
AbstractArticlePDF–784K

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