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Items: 1 to 20 of 171

1.
Protein translation rate determines neocortical neuron fate
Ekaterina Borisova, Andrew G. Newman, Marta Couce Iglesias, Rike Dannenberg, Theres Schaub, Bo Qin, Alexandra Rusanova, Marisa Brockmann, Janina Koch, Marieatou Daniels, Paul Turko, Olaf Jahn, David R. Kaplan, Marta Rosário, Takao Iwawaki, Christian M. T. Spahn, Christian Rosenmund, David Meierhofer, Matthew L. Kraushar, Victor Tarabykin, Mateusz C. Ambrozkiewicz
Nat Commun. 2024; 15: 4879. Published online 2024 Jun 7. doi: 10.1038/s41467-024-49198-w
PMCID:
PMC11161512
AbstractArticlePDF–17M
2.
Vinculin-mediated axon growth requires interaction with actin but not talin in mouse neocortical neurons
Pranay Mandal, Vivek Belapurkar, Deepak Nair, Narendrakumar Ramanan
Cell Mol Life Sci. 2021 Aug; 78(15): 5807–5826. Published online 2021 Jun 20. doi: 10.1007/s00018-021-03879-7
PMCID:
PMC11071915
AbstractArticlePDF–17M
3.
CDCA7-associated global aberrant DNA hypomethylation translates to localized, tissue-specific transcriptional responses
Maja Vukic, Jihed Chouaref, Veronica Della Chiara, Serkan Dogan, Fallon Ratner, Jenna Z. M. Hogenboom, Trevor A. Epp, Kallayanee Chawengsaksophak, Kelly K. D. Vonk, Cor Breukel, Yavuz Ariyurek, David San Leon Granado, Susan L. Kloet, Lucia Daxinger
Sci Adv. 2024 Feb 9; 10(6): eadk3384. Published online 2024 Feb 9. doi: 10.1126/sciadv.adk3384
PMCID:
PMC10857554
AbstractArticlePDF–9.3M
4.
Cleft palate and minor metabolic disturbances in a mouse global Arl15 gene knockout
Ying Bai, Liz Bentley, Chao Ma, Navaratnam Naveenan, James Cleak, Yixing Wu, Michelle M Simon, Henrik Westerberg, Ramón Casero Cañas, Neil Horner, Rajesh Pandey, Keanu Paphiti, Ulrike Schulze, Joffrey Mianné, Tertius Hough, Lydia Teboul, Jeroen H.F. de Baaij, Roger D. Cox
FASEB J. Author manuscript; available in PMC 2024 Nov 1.
Published in final edited form as: FASEB J. 2023 Nov; 37(11): e23211. doi: 10.1096/fj.202201918R
PMCID:
PMC10631251
AbstractArticlePDF–3.1M
5.
Opposing gene regulatory programs governing myofiber development and maturation revealed at single nucleus resolution
Matthieu Dos Santos, Akansha M. Shah, Yichi Zhang, Svetlana Bezprozvannaya, Kenian Chen, Lin Xu, Weichun Lin, John R. McAnally, Rhonda Bassel-Duby, Ning Liu, Eric N. Olson
Nat Commun. 2023; 14: 4333. Published online 2023 Jul 19. doi: 10.1038/s41467-023-40073-8
PMCID:
PMC10356771
AbstractArticlePDF–4.9M
6.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
7.
Vinculin phosphorylation impairs vascular endothelial junctions promoting atherosclerosis
Yu-Tsung Shih, Shu-Yi Wei, Jin-Hua Chen, Wei-Li Wang, Hsin-Yi Wu, Mei-Cun Wang, Chia-Yu Lin, Pei-Lin Lee, Chih-Yuan Lin, Hung-Che Chiang, Yu-Ju Chen, Shu Chien, Jeng-Jiann Chiu
Eur Heart J. 2023 Jan 21; 44(4): 304–318. Published online 2022 Nov 16. doi: 10.1093/eurheartj/ehac647
PMCID:
PMC10202442
AbstractArticlePDF–23M
8.
A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy
Yasuhide Kuwabara, Allen J. York, Suh-Chin Lin, Michelle A. Sargent, Kelly M. Grimes, James P. Pirruccello, Jeffery D. Molkentin
Proc Natl Acad Sci U S A. 2023 May 9; 120(19): e2213696120. Published online 2023 May 1. doi: 10.1073/pnas.2213696120
PMCID:
PMC10175844
AbstractArticlePDF–1.3M
9.
TGFβ pathway is required for viable gestation of Fanconi anemia embryos
Alfredo Rodríguez, Michael Epperly, Jessica Filiatrault, Martha Velázquez, Chunyu Yang, Kelsey McQueen, Larissa A. Sambel, Huy Nguyen, Divya Ramalingam Iyer, Ulises Juárez, Cecilia Ayala-Zambrano, David B. Martignetti, Sara Frías, Renee Fisher, Kalindi Parmar, Joel S. Greenberger, Alan D. D’Andrea
PLoS Genet. 2022 Nov; 18(11): e1010459. Published online 2022 Nov 28. doi: 10.1371/journal.pgen.1010459
PMCID:
PMC9731498
AbstractArticlePDF–3.4M
10.
Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice
Mellissa C. Alcantara, Kentaro Suzuki, Alvin R. Acebedo, Daiki Kajioka, Satoshi Hirohata, Tsuneyasu Kaisho, Yu Hatano, Kazuo Yamagata, Satoru Takahashi, Gen Yamada
iScience. 2022 Dec 22; 25(12): 105609. Published online 2022 Nov 16. doi: 10.1016/j.isci.2022.105609
PMCID:
PMC9713376
AbstractArticlePDF–5.7M
11.
The cell surface hyaluronidase TMEM2 plays an essential role in mouse neural crest cell development and survival
Toshihiro Inubushi, Yuichiro Nakanishi, Makoto Abe, Yoshifumi Takahata, Riko Nishimura, Hiroshi Kurosaka, Fumitoshi Irie, Takashi Yamashiro, Yu Yamaguchi
PLoS Genet. 2022 Jul; 18(7): e1009765. Published online 2022 Jul 15. doi: 10.1371/journal.pgen.1009765
PMCID:
PMC9328550
AbstractArticlePDF–5.3M
12.
Fine-tuned KDM1A alternative splicing regulates human cardiomyogenesis through an enzymatic-independent mechanism
Veronica Astro, Gustavo Ramirez-Calderon, Roberta Pennucci, Jonatan Caroli, Alfonso Saera-Vila, Kelly Cardona-Londoño, Chiara Forastieri, Elisabetta Fiacco, Fatima Maksoud, Maryam Alowaysi, Elisa Sogne, Andrea Falqui, Federico Gonzàlez, Nuria Montserrat, Elena Battaglioli, Andrea Mattevi, Antonio Adamo
iScience. 2022 Jul 15; 25(7): 104665. Published online 2022 Jun 23. doi: 10.1016/j.isci.2022.104665
PMCID:
PMC9287196
AbstractArticlePDF–7.7M
13.
Focal Adhesion Protein Vinculin Is Required for Proper Meiotic Progression during Mouse Spermatogenesis
Jana Petrusová, Robert Havalda, Petr Flachs, Tomáš Venit, Alžběta Darášová, Lenka Hůlková, Martin Sztacho, Pavel Hozák
Cells. 2022 Jul; 11(13): 2013. Published online 2022 Jun 23. doi: 10.3390/cells11132013
PMCID:
PMC9265697
AbstractArticlePDF–6.6M
14.
Znhit1 Regulates p21Cip1 to Control Mouse Lens Differentiation
Juan Lu, Jianhong An, Jiawei Wang, Xiaowen Cao, Yuqing Cao, Chengjie Huang, Shiming Jiao, Dongsheng Yan, Xinhua Lin, Xiangtian Zhou
Invest Ophthalmol Vis Sci. 2022 Apr; 63(4): 18. Published online 2022 Apr 26. doi: 10.1167/iovs.63.4.18
PMCID:
PMC9055562
AbstractArticlePDF–46M
15.
RBFOX2 is required for establishing RNA regulatory networks essential for heart development
Sunil K Verma, Vaibhav Deshmukh, Kaitlyn Thatcher, KarryAnne K Belanger, Alexander M Rhyner, Shu Meng, Richard Joshua Holcomb, Michael Bressan, James F Martin, John P Cooke, Joshua D Wythe, Steven G Widen, Joy Lincoln, Muge N Kuyumcu-Martinez
Nucleic Acids Res. 2022 Feb 28; 50(4): 2270–2286. Published online 2022 Feb 7. doi: 10.1093/nar/gkac055
PMCID:
PMC8881802
AbstractArticlePDF–16M
16.
Differential regulation of cranial and cardiac neural crest by serum response factor and its cofactors
Colin J Dinsmore, Philippe Soriano
eLife. 2022; 11: e75106. Published online 2022 Jan 19. doi: 10.7554/eLife.75106
PMCID:
PMC8806183
AbstractArticlePDF–9.5M
17.
NRF1 Association with AUTS2-Polycomb Mediates Specific Gene Activation in the Brain
Sanxiong Liu, Kimberly A. Aldinger, Chi Vicky Cheng, Takae Kiyama, Mitali Dave, Hanna K. McNamara, Wukui Zhao, James M. Stafford, Nicolas Descostes, Pedro Lee, Stefano G. Caraffi, Ivan Ivanovski, Edoardo Errichiello, Christiane Zweier, Orsetta Zuffardi, Michael Schneider, Antigone S. Papavasiliou, M. Scott Perry, Jennifer Humberson, Megan T. Cho, Astrid Weber, Andrew Swale, Tudor C. Badea, Chai-An Mao, Livia Garavelli, William B. Dobyns, Danny Reinberg
Mol Cell. Author manuscript; available in PMC 2022 Nov 18.
Published in final edited form as: Mol Cell. 2021 Nov 18; 81(22): 4663–4676.e8. Published online 2021 Oct 11. doi: 10.1016/j.molcel.2021.09.020
Correction in:
Mol Cell. 2021 Nov 18; 81(22): 4757.
PMCID:
PMC8604784
AbstractArticlePDF–2.8M
18.
MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus
Karol Kaiser, Ahram Jang, Petra Kompanikova, Melody P. Lun, Jan Prochazka, Ondrej Machon, Neil Dani, Michaela Prochazkova, Benoit Laurent, Daniel Gyllborg, Renee van Amerongen, Ryann M. Fame, Suhasini Gupta, Feizhen Wu, Roger A. Barker, Ivana Bukova, Radislav Sedlacek, Zbynek Kozmik, Ernest Arenas, Maria K. Lehtinen, Vitezslav Bryja
Development. 2021 May 15; 148(10): dev192054. Published online 2021 May 25. doi: 10.1242/dev.192054
Correction in:
Development. 2022 Feb 1; 149(3): dev200517.
PMCID:
PMC8180257
AbstractArticle
19.
Transgenic mice with an R342X mutation in Phf6 display clinical features of Börjeson–Forssman–Lehmann Syndrome
Raies Ahmed, Shihab Sarwar, Jinghua Hu, Valérie Cardin, Lily R Qiu, Gerardo Zapata, Lucianne Vandeleur, Keqin Yan, Jason P Lerch, Mark A Corbett, Jozef Gecz, David J Picketts
Hum Mol Genet. 2021 Apr 1; 30(7): 575–594. Published online 2021 Mar 26. doi: 10.1093/hmg/ddab081
PMCID:
PMC8120135
AbstractArticlePDF–2.4M
20.
NMRK2 Gene Is Upregulated in Dilated Cardiomyopathy and Required for Cardiac Function and NAD Levels during Aging
Cynthia Tannous, Robin Deloux, Ahmed Karoui, Nathalie Mougenot, Dean Burkin, Jocelyne Blanc, Dario Coletti, Gareth Lavery, Zhenlin Li, Mathias Mericskay
Int J Mol Sci. 2021 Apr; 22(7): 3534. Published online 2021 Mar 29. doi: 10.3390/ijms22073534
PMCID:
PMC8036583
AbstractArticlePDF–4.4M

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