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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 96658852.

Mapping Brain Gene Coexpression in Daytime Transcriptomes Unveils Diurnal Molecular Networks and Deciphers Perturbation Gene Signatures

Nan Wang, Peter Langfelder, Matthew Stricos, Lalini Ramanathan, Jeffrey B. Richman, Raymond Vaca, Mary Plascencia, Xiaofeng Gu, Shasha Zhang, T. Katherine Tamai, Liguo Zhang, Fuying Gao, Koliane Ouk, Xiang Lu, Leonya Ivanov, Tom Vogt, Qing Richard Lu, A. Jennifer Morton, Christopher Colwell, Jeffrey S. Aaronson, Jim Rosinski, Steve Horvath, X. William Yang

Neuron. Author manuscript; available in PMC 2023 Oct 19.

Published in final edited form as: Neuron. 2022 Oct 19; 110(20): 3318–3338.e9. doi: 10.1016/j.neuron.2022.09.028

PMCID:: PMC9665885

Abstract Article PDF–4.5M

Select item 90714033.

Histone H3.3 phosphorylation promotes heterochromatin formation by inhibiting H3K9/K36 histone demethylase

Maheshi Udugama, Benjamin Vinod, F Lyn Chan, Linda Hii, Andrew Garvie, Philippe Collas, Paul Kalitsis, David Steer, Partha P Das, Pratibha Tripathi, Jeffrey R Mann, Hsiao P J Voon, Lee H Wong

Nucleic Acids Res. 2022 May 6; 50(8): 4500–4514. Published online 2022 Apr 22. doi: 10.1093/nar/gkac259

PMCID:: PMC9071403

Abstract Article PDF–17M

Select item 83338714.

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice

Feng Zhang, Xiong Zhao, Runmin Jiang, Yuying Wang, Xinli Wang, Yu Gu, Longyong Xu, Jing Ye, Charlie Degui Chen, Shuangping Guo, Dawei Zhang, Daqing Zhao

Front Cell Dev Biol. 2021; 9: 642931. Published online 2021 Jul 21. doi: 10.3389/fcell.2021.642931

PMCID:: PMC8333871

Abstract Article PDF–1.4M

Select item 83132395.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 81105566.

Mutations inhibiting KDM4B drive ALT activation in ATRX-mutated glioblastomas

M. Udugama, L. Hii, A. Garvie, M. Cervini, B. Vinod, F.-L. Chan, P. P. Das, J. R. Mann, P. Collas, H. P. J. Voon, L. H. Wong

Nat Commun. 2021; 12: 2584. Published online 2021 May 10. doi: 10.1038/s41467-021-22543-z

PMCID:: PMC8110556

Abstract Article PDF–5.3M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78206208.

Heterozygous Variants in KDM4B Lead to Global Developmental Delay and Neuroanatomical Defects

Anna R. Duncan, Antonio Vitobello, Stephan C. Collins, Valerie E. Vancollie, Christopher J. Lelliott, Lance Rodan, Jiahai Shi, Ann R. Seman, Emanuele Agolini, Antonio Novelli, Paolo Prontera, Maria J. Guillen Sacoto, Teresa Santiago-Sim, Aurélien Trimouille, Cyril Goizet, Mathilde Nizon, Ange-Line Bruel, Christophe Philippe, Patricia E. Grant, Monica H. Wojcik, Joan Stoler, Casie A. Genetti, Marieke F. van Dooren, Saskia M. Maas, Marielle Alders, Laurence Faivre, Arthur Sorlin, Grace Yoon, Binnaz Yalcin, Pankaj B. Agrawal

Am J Hum Genet. 2020 Dec 3; 107(6): 1170–1177. Published online 2020 Nov 23. doi: 10.1016/j.ajhg.2020.11.001

PMCID:: PMC7820620

Abstract Article PDF–1.6M

Select item 78067429.

Histone demethylase JMJD2B/KDM4B regulates transcriptional program via distinctive epigenetic targets and protein interactors for the maintenance of trophoblast stem cells

Kylie Hin-Man Mak, Yuk Man Lam, Ray Kit Ng

Sci Rep. 2021; 11: 884. Published online 2021 Jan 13. doi: 10.1038/s41598-020-79601-7

PMCID:: PMC7806742

Abstract Article PDF–8.7M

Select item 766420210.

Histone H3K9 Demethylase JMJD2B Plays a Role in LXRα-Dependent Lipogenesis

Ji-Hyun Kim, Dae Young Jung, Hye-Ran Kim, Myeong Ho Jung

Int J Mol Sci. 2020 Nov; 21(21): 8313. Published online 2020 Nov 5. doi: 10.3390/ijms21218313

PMCID:: PMC7664202

Abstract Article PDF–25M

Select item 752431311.

Enterotoxigenic Bacteroides fragilis induces the stemness in colorectal cancer via upregulating histone demethylase JMJD2B

Qian-Qian Liu, Chun-Min Li, Lin-Na Fu, Hao-Lian Wang, Juan Tan, Yun-Qian Wang, Dan-Feng Sun, Qin-Yan Gao, Ying-Xuan Chen, Jing-Yuan Fang

Gut Microbes. 2020; 12(1): 1788900. Published online 2020 Jul 20. doi: 10.1080/19490976.2020.1788900

PMCID:: PMC7524313

Abstract Article PDF–12M

Select item 704914712.

The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition

Simone F. Glaser, Andreas W. Heumüller, Lukas Tombor, Patrick Hofmann, Marion Muhly-Reinholz, Ariane Fischer, Stefan Günther, Karoline E. Kokot, Hitoshi Okada, David Hassel, Sandeep Kumar, Hanjoong Jo, Reinier A. Boon, Wesley Abplanalp, David John, Jes-Niels Boeckel, Stefanie Dimmeler

Proc Natl Acad Sci U S A. 2020 Feb 25; 117(8): 4180–4187. Published online 2020 Feb 7. doi: 10.1073/pnas.1913481117

Correction in:: Proc Natl Acad Sci U S A. 2020 Apr 14; 117(15): 8657.

PMCID:: PMC7049147

Abstract Article PDF–1.2M

Select item 677679413.

The KDM4/JMJD2 histone demethylases are required for hematopoietic stem cell maintenance

Karl Agger, Koutarou Nishimura, Satoru Miyagi, Jan-Erik Messling, Kasper Dindler Rasmussen, Kristian Helin

Blood. 2019 Oct 3; 134(14): 1154–1158. Prepublished online 2019 Aug 21. doi: 10.1182/blood.2019000855

PMCID:: PMC6776794

Abstract Article

Select item 645951014.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 628366315.

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition

John Arne Dahl, Inkyung Jung, Håvard Aanes, Gareth D. Greggains, Adeel Manaf, Mads Lerdrup, Guoqiang Li, Samantha Kuan, Bin Li, Ah Young Lee, Sebastian Preissl, Ingunn Jermstad, Mads Haugland Haugen, Rajikala Suganthan, Magnar Bjørås, Klaus Hansen, Knut Tomas Dalen, Peter Fedorcsak, Bing Ren, Arne Klungland

Nature. Author manuscript; available in PMC 2018 Dec 6.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 548–552. Published online 2016 Sep 14. doi: 10.1038/nature19360

PMCID:: PMC6283663

Abstract Article PDF–4.9M

Select item 613722116.

Histone H3K9 demethylase JMJD2B induces hepatic steatosis through upregulation of PPARγ2

Ji-Hyun Kim, Dae Young Jung, Arulkumar Nagappan, Myeong Ho Jung

Sci Rep. 2018; 8: 13734. Published online 2018 Sep 13. doi: 10.1038/s41598-018-31953-x

PMCID:: PMC6137221

Abstract Article PDF–1.8M

Select item 600448417.

KDM4B protects against obesity and metabolic dysfunction

Yingduan Cheng, Quan Yuan, Laurent Vergnes, Xin Rong, Ji Youn Youn, Jiong Li, Yongxin Yu, Wei Liu, Hua Cai, Jiandie D. Lin, Peter Tontonoz, Christine Hong, Karen Reue, Cun-Yu Wang

Proc Natl Acad Sci U S A. 2018 Jun 12; 115(24): E5566–E5575. Published online 2018 May 29. doi: 10.1073/pnas.1721814115