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Select item 110066921.

CaMKⅡγ和CaMKⅡδ通过PI3K/Akt/Erk信号通路减轻小鼠神经元缺血再灌注损伤

刘昊铭, 林子诗, 叶靖

Nan Fang Yi Ke Da Xue Xue Bao. 2024 Mar 20; 44(3): 563–570. Chinese. doi: 10.12122/j.issn.1673-4254.2024.03.18

PMCID:: PMC11006692

Abstract Article PDF–2.1M

Select item 107835752.

Using CRISPR-Cas9/phosphoproteomics to identify substrates of calcium/calmodulin-dependent kinase 2δ

Euijung Park, Chin-Rang Yang, Viswanathan Raghuram, Lihe Chen, Chung-Lin Chou, Mark A. Knepper

J Biol Chem. 2023 Dec; 299(12): 105371. Published online 2023 Oct 20. doi: 10.1016/j.jbc.2023.105371

PMCID:: PMC10783575

Abstract Article PDF–2.7M

Select item 96434383.

Oxidative stress–induced autonomous activation of the calcium/calmodulin-dependent kinase II involves disulfide formation in the regulatory domain

Nathália Rocco-Machado, Lo Lai, Geumsoo Kim, Yi He, Elizabeth D. Luczak, Mark E. Anderson, Rodney L. Levine

J Biol Chem. 2022 Nov; 298(11): 102579. Published online 2022 Oct 8. doi: 10.1016/j.jbc.2022.102579

PMCID:: PMC9643438

Abstract Article PDF–2.1M

Select item 96361504.

Lamin A/C-dependent chromatin architecture safeguards naïve pluripotency to prevent aberrant cardiovascular cell fate and function

Yinuo Wang, Adel Elsherbiny, Linda Kessler, Julio Cordero, Haojie Shi, Heike Serke, Olga Lityagina, Felix A. Trogisch, Mona Malek Mohammadi, Ibrahim El-Battrawy, Johannes Backs, Thomas Wieland, Joerg Heineke, Gergana Dobreva

Nat Commun. 2022; 13: 6663. Published online 2022 Nov 4. doi: 10.1038/s41467-022-34366-7

PMCID:: PMC9636150

Abstract Article PDF–8.9M

Select item 96038605.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 89831436.

Dendritic cell immunoreceptor drives atopic dermatitis by modulating oxidized CaMKII-involved mast cell activation

Xiaoyan Luo, Jingsi Chen, Huan Yang, Xinyue Hu, Martin P. Alphonse, Yingchun Shen, Yuko Kawakami, Xiaoying Zhou, Wei Tu, Toshiaki Kawakami, Mei Wan, Nathan K. Archer, Hua Wang, Peisong Gao

JCI Insight. 2022 Mar 8; 7(5): e152559. Published online 2022 Mar 8. doi: 10.1172/jci.insight.152559

PMCID:: PMC8983143

Abstract Article PDF–16M

Select item 86938637.

ERK1/2 inhibition promotes robust myotube growth via CaMKII activation resulting in myoblast-to-myotube fusion

Tamar Eigler, Giulia Zarfati, Emmanuel Amzallag, Sansrity Sinha, Nadav Segev, Yishaia Zabary, Assaf Zaritsky, Avraham Shakked, Kfir-Baruch Umansky, Eyal D. Schejter, Douglas P. Millay, Eldad Tzahor, Ori Avinoam

Dev Cell. 2021 Dec 20; 56(24): 3349–3363.e6. doi: 10.1016/j.devcel.2021.11.022

PMCID:: PMC8693863

Abstract Article

Select item 84610298.

The oxidation‐resistant CaMKII‐MM281/282VV mutation does not prevent arrhythmias in CPVT1

Mani Sadredini, Ravinea Manotheepan, Stephan E. Lehnart, Mark E. Anderson, Ivar Sjaastad, Mathis K. Stokke

Physiol Rep. 2021 Sep; 9(18): e15030. Published online 2021 Sep 23. doi: 10.14814/phy2.15030

PMCID:: PMC8461029

Abstract Article PDF–1.5M

Select item 83655269.

Adipocyte CAMK2 deficiency improves obesity-associated glucose intolerance

Wen Dai, Mayank Choubey, Sonal Patel, Harold A. Singer, Lale Ozcan

Mol Metab. 2021 Nov; 53: 101300. Published online 2021 Jul 22. doi: 10.1016/j.molmet.2021.101300

PMCID:: PMC8365526

Abstract Article PDF–2.9M

Select item 834924510.

Hyperglycemia regulates cardiac K⁺ channels via O-GlcNAc-CaMKII and NOX2-ROS-PKC pathways

Bence Hegyi, Johanna M. Borst, Logan R. J. Bailey, Erin Y. Shen, Austen J. Lucena, Manuel F. Navedo, Julie Bossuyt, Donald M. Bers

Basic Res Cardiol. Author manuscript; available in PMC 2021 Nov 25.

Published in final edited form as: Basic Res Cardiol. 2020 Nov 25; 115(6): 71. Published online 2020 Nov 25. doi: 10.1007/s00395-020-00834-8

PMCID:: PMC8349245

Abstract Article PDF–5.4M

Select item 822373911.

CaMKIIδ is upregulated by proinflammatory cytokine IL-6 in a JAK/STAT3-dependent manner to promote angiogenesis

Brendan J. O’Brien, Harold A. Singer, Alejandro P. Adam, Roman G. Ginnan

FASEB J. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: FASEB J. 2021 Apr; 35(4): e21437. doi: 10.1096/fj.202002755R

PMCID:: PMC8223739

Abstract Article PDF–2.4M

Select item 793877012.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 773649013.

CaMKII exacerbates heart failure progression by activating class I HDACs

Manling Zhang, Xue Yang, Raymond J. Zimmerman, Qin Wang, Mark A. Ross, Jonathan M. Granger, Elizabeth D. Luczak, Djahida Bedja, Hong Jiang, Ning Feng

J Mol Cell Cardiol. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: J Mol Cell Cardiol. 2020 Dec; 149: 73–81. Published online 2020 Sep 22. doi: 10.1016/j.yjmcc.2020.09.007

PMCID:: PMC7736490

Abstract Article PDF–1.8M

Select item 771970814.

Sphingosine kinase 1 regulates HMGB1 translocation by directly interacting with calcium/calmodulin protein kinase II-δ in sepsis-associated liver injury

Tao Tian, Danhua Yao, Lei Zheng, Zhiyuan Zhou, Yantao Duan, Bin Liu, Pengfei Wang, Yousheng Li

Cell Death Dis. 2020 Dec; 11(12): 1037. Published online 2020 Dec 6. doi: 10.1038/s41419-020-03255-6

PMCID:: PMC7719708

Abstract Article PDF–2.6M

Select item 745624415.

MICAL1 constrains cardiac stress responses and protects against disease by oxidizing CaMKII

Klitos Konstantinidis, Vassilios J. Bezzerides, Lo Lai, Holly M. Isbell, An-Chi Wei, Yuejin Wu, Meera C. Viswanathan, Ian D. Blum, Jonathan M. Granger, Danielle Heims-Waldron, Donghui Zhang, Elizabeth D. Luczak, Kevin R. Murphy, Fujian Lu, Daniel H. Gratz, Bruno Manta, Qiang Wang, Qinchuan Wang, Alex L. Kolodkin, Vadim N. Gladyshev, Thomas J. Hund, William T. Pu, Mark N. Wu, Anthony Cammarato, Mario A. Bianchet, Madeline A. Shea, Rodney L. Levine, Mark E. Anderson

J Clin Invest. 2020 Sep 1; 130(9): 4663–4678. Published online 2020 Aug 4. doi: 10.1172/JCI133181

PMCID:: PMC7456244

Abstract Article PDF–5.9M

Select item 699392516.

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers

Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang

FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R

PMCID:: PMC6993925

Abstract Article

Select item 682526217.

CaM kinase II regulates cardiac hemoglobin expression through histone phosphorylation upon sympathetic activation

Ali Reza Saadatmand, Viviana Sramek, Silvio Weber, Daniel Finke, Matthias Dewenter, Carsten Sticht, Norbert Gretz, Till Wüstemann, Marco Hagenmueller, Stephan R. Kuenzel, Stefanie Meyer-Roxlau, Martin Kramer, Samuel Sossalla, Lorenz H. Lehmann, Susanne Kämmerer, Johannes Backs, Ali El-Armouche

Proc Natl Acad Sci U S A. 2019 Oct 29; 116(44): 22282–22287. Published online 2019 Oct 16. doi: 10.1073/pnas.1816521116

PMCID:: PMC6825262

Abstract Article PDF–1.0M

Select item 662276618.

Aberrant Calcium/Calmodulin-Dependent Protein Kinase II (CaMKII) Activity Is Associated with Abnormal Dendritic Spine Morphology in the ATRX Mutant Mouse Brain

Norifumi Shioda, Hideyuki Beppu, Takaichi Fukuda, En Li, Isao Kitajima, Kohji Fukunaga

J Neurosci. 2011 Jan 5; 31(1): 346–358. doi: 10.1523/JNEUROSCI.4816-10.2011

PMCID:: PMC6622766

Abstract Article PDF–3.2M

Select item 661435719.

Genetic deletion of calcium/calmodulin-dependent protein kinase type II delta does not mitigate adverse myocardial remodeling in volume-overloaded hearts

Belal A. Mohamed, Manar Elkenani, Joanna Jakubiczka-Smorag, Eric Buchholz, Sabrina Koszewa, Dawid Lbik, Moritz Schnelle, Gerd Hasenfuss, Karl Toischer

Sci Rep. 2019; 9: 9889. Published online 2019 Jul 8. doi: 10.1038/s41598-019-46332-3

PMCID:: PMC6614357

Abstract Article PDF–1.9M

Select item 659500120.

Myocardial death and dysfunction after ischemia-reperfusion injury require CaMKIIδ oxidation

Yuejin Wu, Qinchuan Wang, Ning Feng, Jonathan M. Granger, Mark E. Anderson

Sci Rep. 2019; 9: 9291. Published online 2019 Jun 26. doi: 10.1038/s41598-019-45743-6

PMCID:: PMC6595001

Abstract Article PDF–5.4M

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