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Items: 1 to 20 of 53

1.
Vascular endothelial-derived SPARCL1 exacerbates viral pneumonia through pro-inflammatory macrophage activation
Gan Zhao, Maria E. Gentile, Lulu Xue, Christopher V. Cosgriff, Aaron I. Weiner, Stephanie Adams-Tzivelekidis, Joanna Wong, Xinyuan Li, Sara Kass-Gergi, Nicolas P. Holcomb, Maria C. Basal, Kathleen M. Stewart, Joseph D. Planer, Edward Cantu, Jason D. Christie, Maria M. Crespo, Michael J. Mitchell, Nuala J. Meyer, Andrew E. Vaughan
Nat Commun. 2024; 15: 4235. Published online 2024 May 18. doi: 10.1038/s41467-024-48589-3
PMCID:
PMC11102455
AbstractArticlePDF–4.2M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Single cell RNA analysis of the left–right organizer transcriptome reveals potential novel heterotaxy genes
Helen M. Bellchambers, Amruta R. Phatak, Mardi J. Nenni, Maria B. Padua, Hongyu Gao, Yunlong Liu, Stephanie M. Ware
Sci Rep. 2023; 13: 10688. Published online 2023 Jul 1. doi: 10.1038/s41598-023-36862-2
PMCID:
PMC10314903
AbstractArticlePDF–3.5M
4.
The Matricellular Protein Hevin Is Involved in Alcohol Use Disorder
Amaia Nuñez-delMoral, Paula C. Bianchi, Iria Brocos-Mosquera, Augusto Anesio, Paola Palombo, Rosana Camarini, Fabio C. Cruz, Luis F. Callado, Vincent Vialou, Amaia M. Erdozain
Biomolecules. 2023 Feb; 13(2): 234. Published online 2023 Jan 25. doi: 10.3390/biom13020234
PMCID:
PMC9953008
AbstractArticlePDF–2.0M
5.
Hevin/Sparcl1 drives pathological pain through spinal cord astrocyte and NMDA receptor signaling
Gang Chen, Jing Xu, Hao Luo, Xin Luo, Sandeep K. Singh, Juan J. Ramirez, Michael L. James, Joseph P. Mathew, Miles Berger, Cagla Eroglu, Ru-Rong Ji
JCI Insight. 2022 Dec 8; 7(23): e161028. Published online 2022 Dec 8. doi: 10.1172/jci.insight.161028
PMCID:
PMC9746899
AbstractArticlePDF–2.2M
6.
Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex
Xiaoping Wu, Alexander A. Sosunov, Wudu Lado, Jia Jie Teoh, Ahrom Ham, Hongyu Li, Osama Al-Dalahmah, Brian J.A. Gill, Ottavio Arancio, Catherine A. Schevon, Wayne N. Frankel, Guy M. McKhann, II, David Sulzer, James E. Goldman, Guomei Tang
Cell Rep. Author manuscript; available in PMC 2022 Aug 14.
Published in final edited form as: Cell Rep. 2022 Jul 19; 40(3): 111085. doi: 10.1016/j.celrep.2022.111085
PMCID:
PMC9376014
AbstractArticlePDF–4.2M
7.
Autism-associated mutation in Hevin/Sparcl1 induces endoplasmic reticulum stress through structural instability
Takumi Taketomi, Takunori Yasuda, Rikuri Morita, Jaehyun Kim, Yasuteru Shigeta, Cagla Eroglu, Ryuhei Harada, Fuminori Tsuruta
Sci Rep. 2022; 12: 11891. Published online 2022 Jul 13. doi: 10.1038/s41598-022-15784-5
PMCID:
PMC9279342
AbstractArticlePDF–6.5M
8.
Molecular divergence of mammalian astrocyte progenitor cells at early gliogenesis
Jiancheng Liu, Xiwei Wu, Qiang Lu
Development. 2022 Mar 1; 149(5): dev199985. Published online 2022 Mar 7. doi: 10.1242/dev.199985
PMCID:
PMC8959143
AbstractArticle
9.
Integration of single-cell transcriptomes and chromatin landscapes reveals regulatory programs driving pharyngeal organ development
Margaret E. Magaletta, Macrina Lobo, Eric M. Kernfeld, Hananeh Aliee, Jack D. Huey, Teagan J. Parsons, Fabian J. Theis, René Maehr
Nat Commun. 2022; 13: 457. Published online 2022 Jan 24. doi: 10.1038/s41467-022-28067-4
PMCID:
PMC8786836
AbstractArticlePDF–5.6M
10.
Sparcl1 promotes nonalcoholic steatohepatitis progression in mice through upregulation of CCL2
Bin Liu, Liping Xiang, Jing Ji, Wei Liu, Ying Chen, Mingfeng Xia, Yuejun Liu, Wenyue Liu, Peiwu Zhu, Yi Jin, Yu Han, Jieli Lu, Xiaoying Li, Minghua Zheng, Yan Lu
J Clin Invest. 2021 Oct 15; 131(20): e144801. Published online 2021 Oct 15. doi: 10.1172/JCI144801
PMCID:
PMC8516465
AbstractArticlePDF–12M
11.
Roles of the synaptic molecules Hevin and SPARC in mouse neuromuscular junction development and repair
Vanessa L. Brayman, Thomas Taetzsch, MacKenzie Miko, Shreyaska Dahal, W. Christopher Risher, Gregorio Valdez
Neurosci Lett. Author manuscript; available in PMC 2022 Feb 16.
Published in final edited form as: Neurosci Lett. 2021 Feb 16; 746: 135663. Published online 2021 Jan 22. doi: 10.1016/j.neulet.2021.135663
PMCID:
PMC8418192
AbstractArticlePDF–939K
12.
Matricellular Protein SPARCL1 Regulates Blood Vessel Integrity and Antagonizes Inflammatory Bowel Disease
Daniela Regensburger, Clara Tenkerian, Victoria Pürzer, Benjamin Schmid, Thomas Wohlfahrt, Iris Stolzer, Rocío López-Posadas, Claudia Günther, Maximilian J Waldner, Christoph Becker, Heinrich Sticht, Katja Petter, Christian Flierl, Tobias Gass, Tim Thoenissen, Carol I Geppert, Nathalie Britzen-Laurent, Valérie S Méniel, Andreas Ramming, Michael Stürzl, Elisabeth Naschberger
Inflamm Bowel Dis. 2021 Sep; 27(9): 1491–1502. Published online 2021 Jan 4. doi: 10.1093/ibd/izaa346
PMCID:
PMC8376124
AbstractArticlePDF–11M
13.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
14.
SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins
Kathlyn J. Gan, Thomas C. Südhof
J Neurosci. 2020 Oct 14; 40(42): 8088–8102. doi: 10.1523/JNEUROSCI.0454-20.2020
PMCID:
PMC7574652
AbstractArticlePDF–6.0M
15.
A chromatin modulator sustains self-renewal and enables differentiation of postnatal neural stem and progenitor cells
Kushani Shah, Gwendalyn D King, Hao Jiang
J Mol Cell Biol. 2020 Jan; 12(1): 4–16. Published online 2019 Aug 23. doi: 10.1093/jmcb/mjz036
PMCID:
PMC7052987
AbstractArticlePDF–1.4M
16.
Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment
Kathlyn J. Gan, Thomas C. Südhof
Proc Natl Acad Sci U S A. 2019 Jun 18; 116(25): 12524–12533. Published online 2019 Jun 3. doi: 10.1073/pnas.1902672116
PMCID:
PMC6589664
AbstractArticlePDF–2.6M
17.
Spatiotemporal differences in otoconial gene expression
Yinfang Xu, Yan Zhang, Yunxia Wang Lundberg
Genesis. Author manuscript; available in PMC 2018 Apr 24.
Published in final edited form as: Genesis. 2016 Dec; 54(12): 613–625. Published online 2016 Nov 12. doi: 10.1002/dvg.22990
PMCID:
PMC5914167
AbstractArticlePDF–1.6M
18.
SPARCL1 suppresses osteosarcoma metastasis and recruits macrophages by activation of canonical WNT/β-catenin signaling through stabilization of the WNT–receptor complex
S-J Zhao, Y-Q Jiang, N-W Xu, Q Li, Q Zhang, S-Y Wang, J Li, Y-H Wang, Y-L Zhang, S-H Jiang, Y-J Wang, Y-J Huang, X-X Zhang, G-A Tian, C-C Zhang, Y-Y Lv, M Dai, F Liu, R Zhang, D Zhou, Z-G Zhang
Oncogene. 2018 Feb 22; 37(8): 1049–1061. Published online 2017 Oct 30. doi: 10.1038/onc.2017.403
PMCID:
PMC5851113
AbstractArticlePDF–4.8M
19.
Matricellular protein SPARCL1 regulates tumor microenvironment–dependent endothelial cell heterogeneity in colorectal carcinoma
Elisabeth Naschberger, Andrea Liebl, Vera S. Schellerer, Manuela Schütz, Nathalie Britzen-Laurent, Patrick Kölbel, Ute Schaal, Lisa Haep, Daniela Regensburger, Thomas Wittmann, Ludger Klein-Hitpass, Tilman T. Rau, Barbara Dietel, Valérie S. Méniel, Alan R. Clarke, Susanne Merkel, Roland S. Croner, Werner Hohenberger, Michael Stürzl
J Clin Invest. 2016 Nov 1; 126(11): 4187–4204. Published online 2016 Oct 10. doi: 10.1172/JCI78260
PMCID:
PMC5096916
AbstractArticlePDF–6.6M
20.
Gene expression analysis of the embryonic subplate
Franziska M. Oeschger, Wei-Zhi Wang, Sheena Lee, Fernando García-Moreno, André M. Goffinet, Mariona Arbones, Sonia Rakic, Zoltán Molnár
Cereb Cortex. Author manuscript; available in PMC 2016 Aug 3.
Published in final edited form as: Cereb Cortex. 2012 Jun; 22(6): 1343–1359. Published online 2011 Aug 22. doi: 10.1093/cercor/bhr197
PMCID:
PMC4972418
AbstractArticlePDF–7.1M

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