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Items: 1 to 20 of 40

1.
Inhibition of the MALT1-LPCAT3 axis protects cartilage degeneration and osteoarthritis
Vijay Kondreddy, Rajkumar Banerjee, B. L. A. Prabhavathi Devi, Kathirvel Muralidharan, Selvakumar Piramanayagam
Cell Commun Signal. 2024; 22: 189. Published online 2024 Mar 22. doi: 10.1186/s12964-024-01547-4
PMCID:
PMC10960471
AbstractArticlePDF–2.4M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Targeting phospholipid remodeling pathway improves insulin resistance in diabetic mouse models
Ye Tian, Wei Lu, Ruicheng Shi, Reagan McGuffee, Richard Lee, David A. Ford, Bo Wang
FASEB J. Author manuscript; available in PMC 2024 Nov 1.
Published in final edited form as: FASEB J. 2023 Nov; 37(11): e23251. doi: 10.1096/fj.202301122RR
PMCID:
PMC10575708
AbstractArticlePDF–3.0M
4.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
5.
Lysophospholipid acylation modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle
Patrick J. Ferrara, Xin Rong, J. Alan Maschek, Anthony R.P. Verkerke, Piyarat Siripoksup, Haowei Song, Thomas D. Green, Karthickeyan C. Krishnan, Jordan M. Johnson, John Turk, Joseph A. Houmard, Aldons J. Lusis, Micah J. Drummond, Joseph M. McClung, James E. Cox, Saame Raza Shaikh, Peter Tontonoz, William L. Holland, Katsuhiko Funai
J Clin Invest. 2021 Apr 15; 131(8): e135963. Published online 2021 Apr 15. doi: 10.1172/JCI135963
PMCID:
PMC8262507
AbstractArticlePDF–6.0M
6.
Lysophosphatidylcholine acyltransferase 3 deficiency activates the Wnt/β-catenin pathway and thereby impairs adipogenesis in preadipocytes
Chunyan Feng, Bin Lou, Jibin Dong, Zhiqiang Li, Yunqin Chen, Yue Li, Xuemei Zhang, Xian-Cheng Jiang, Tingbo Ding
Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2021 Mar 29.
Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2018 Aug; 1863(8): 834–843. Published online 2018 Apr 17. doi: 10.1016/j.bbalip.2018.04.008
PMCID:
PMC8006744
AbstractArticlePDF–817K
7.
Deletion of lysophosphatidylcholine acyltransferase 3 in myeloid cells worsens hepatic steatosis after a high-fat diet
Thibaut Bourgeois, Antoine Jalil, Charles Thomas, Charlène Magnani, Naig Le Guern, Thomas Gautier, Jean-Paul Pais de Barros, Victoria Bergas, Hélène Choubley, Loïc Mazzeo, Louise Menegaut, Lorène Josiane Lebrun, Kévin Van Dongen, Marion Xolin, Tony Jourdan, Chloé Buch, Jérome Labbé, Philippe Saas, Laurent Lagrost, David Masson, Jacques Grober
J Lipid Res. 2021; 62: 100013. Published online 2020 Dec 17. doi: 10.1194/jlr.RA120000737
PMCID:
PMC7859853
AbstractArticlePDF–3.8M
8.
ABHD12 and LPCAT3 interplay regulates a lyso-phosphatidylserine-C20:4 phosphatidylserine lipid network implicated in neurological disease
Taka-Aki Ichu, Alex Reed, Daisuke Ogasawara, Olesya Ulanovskaya, Amanda Roberts, Carlos A. Aguirre, Liron Bar-Peled, Jie Gao, Jason Germain, Sabrina Barbas, Kim Masuda, Bruno Conti, Peter Tontonoz, Benjamin F. Cravatt
Biochemistry. Author manuscript; available in PMC 2021 May 19.
Published in final edited form as: Biochemistry. 2020 May 19; 59(19): 1793–1799. Published online 2020 May 4. doi: 10.1021/acs.biochem.0c00292
PMCID:
PMC7394188
AbstractArticlePDF–1.2M
9.
The role of the small intestine in modulating metabolism and inflammation in atherosclerosis and cancer
Pallavi Mukherjee, Arnab Chattopadhyay, Alan M. Fogelman
Curr Opin Lipidol. Author manuscript; available in PMC 2020 Oct 1.
Published in final edited form as: Curr Opin Lipidol. 2019 Oct; 30(5): 383–387. doi: 10.1097/MOL.0000000000000629
PMCID:
PMC6953609
AbstractArticlePDF–302K
10.
LXR Suppresses Inflammatory Gene Expression and Neutrophil Migration through cis-Repression and Cholesterol Efflux
David G. Thomas, Amanda C. Doran, Panagiotis Fotakis, Marit Westerterp, Per Antonson, Hui Jiang, Xian-Cheng Jiang, Jan-Åke Gustafsson, Ira Tabas, Alan R. Tall
Cell Rep. Author manuscript; available in PMC 2019 Apr 3.
Published in final edited form as: Cell Rep. 2018 Dec 26; 25(13): 3774–3785.e4. doi: 10.1016/j.celrep.2018.11.100
PMCID:
PMC6446575
AbstractArticlePDF–2.8M
11.
Macrophage Lysophosphatidylcholine Acyltransferase 3 Deficiency-Mediated Inflammation Is Not Sufficient to Induce Atherosclerosis in a Mouse Model
Hui Jiang, Zhiqiang Li, Chongmin Huan, Xian-Cheng Jiang
Front Cardiovasc Med. 2018; 5: 192. Published online 2019 Jan 17. doi: 10.3389/fcvm.2018.00192
PMCID:
PMC6344406
AbstractArticlePDF–2.7M
12.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
13.
Phospholipid remodeling and cholesterol availability regulate intestinal stemness and tumorigenesis
Bo Wang, Xin Rong, Elisa N.D. Palladino, Jiafang Wang, Alan M. Fogelman, Martín G. Martín, Waddah A. Alrefai, David A. Ford, Peter Tontonoz
Cell Stem Cell. Author manuscript; available in PMC 2019 Feb 1.
Published in final edited form as: Cell Stem Cell. 2018 Feb 1; 22(2): 206–220.e4. doi: 10.1016/j.stem.2017.12.017
PMCID:
PMC5807072
AbstractArticlePDF–3.0M
14.
ER phospholipid composition modulates lipogenesis during feeding and in obesity
Xin Rong, Bo Wang, Elisa N.D. Palladino, Thomas Q. de Aguiar Vallim, David A. Ford, Peter Tontonoz
J Clin Invest. 2017 Oct 2; 127(10): 3640–3651. Published online 2017 Aug 28. doi: 10.1172/JCI93616
PMCID:
PMC5617651
AbstractArticlePDF–6.9M
15.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
16.
The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4WDTC1 E3 ligase
Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong
EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500
PMCID:
PMC5341520
AbstractArticlePDF–1.1M
17.
Intestinal NCoR1, a regulator of epithelial cell maturation, controls neonatal hyperbilirubinemia
Shujuan Chen, Wenqi Lu, Mei-Fei Yueh, Eva Rettenmeier, Miao Liu, Miles Paszek, Johan Auwerx, Ruth T. Yu, Ronald M. Evans, Kepeng Wang, Michael Karin, Robert H. Tukey
Proc Natl Acad Sci U S A. 2017 Feb 21; 114(8): E1432–E1440. Published online 2017 Feb 6. doi: 10.1073/pnas.1700232114
Correction in:
Proc Natl Acad Sci U S A. 2017 May 16; 114(20): E4115.
PMCID:
PMC5338369
AbstractArticlePDF–1.5M
18.
Identification of Hepatic Lysophosphatidylcholine Acyltransferase 3 as a Novel Target Gene Regulated by Peroxisome Proliferator-activated Receptor δ
Amar Bahadur Singh, Jingwen Liu
J Biol Chem. 2017 Jan 20; 292(3): 884–897. Published online 2016 Dec 2. doi: 10.1074/jbc.M116.743575
PMCID:
PMC5247661
AbstractArticlePDF–680K
19.
Small Intestine but Not Liver Lysophosphatidylcholine Acyltransferase 3 (Lpcat3) Deficiency Has a Dominant Effect on Plasma Lipid Metabolism
Inamul Kabir, Zhiqiang Li, Hai H. Bui, Ming-Shang Kuo, Guangping Gao, Xian-Cheng Jiang
J Biol Chem. 2016 Apr 1; 291(14): 7651–7660. Published online 2016 Jan 31. doi: 10.1074/jbc.M115.697011
PMCID:
PMC4817191
AbstractArticlePDF–2.4M
20.
Intestinal phospholipid remodeling is required for dietary lipid uptake and survival on a high-fat diet
Bo Wang, Xin Rong, Mark A. Duerr, Daniel J. Hermanson, Per Niklas Hedde, Jinny S. Wong, Thomas Q. de Aguiar Vallim, Benjamin F. Cravatt, Enrico Gratton, David A. Ford, Peter Tontonoz
Cell Metab. Author manuscript; available in PMC 2017 Mar 8.
Published in final edited form as: Cell Metab. 2016 Mar 8; 23(3): 492–504. Published online 2016 Jan 28. doi: 10.1016/j.cmet.2016.01.001
PMCID:
PMC4785086
AbstractArticlePDF–3.4M

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