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Items: 1 to 20 of 79

1.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
2.
Identification of an FMNL2 Interactome by Quantitative Mass Spectrometry
Sarah Fox, Antoine Gaudreau-LaPierre, Ryan Reshke, Irina Podinic, Derrick J. Gibbings, Laura Trinkle-Mulcahy, John W. Copeland
Int J Mol Sci. 2024 Jun; 25(11): 5686. Published online 2024 May 23. doi: 10.3390/ijms25115686
PMCID:
PMC11171801
AbstractArticlePDF–3.1M
3.
Mechanism of human PINK1 activation at the TOM complex in a reconstituted system
Olawale G. Raimi, Hina Ojha, Kenneth Ehses, Verena Dederer, Sven M. Lange, Cristian Polo Rivera, Tom D. Deegan, Yinchen Chen, Melanie Wightman, Rachel Toth, Karim P. M. Labib, Sebastian Mathea, Neil Ranson, Rubén Fernández-Busnadiego, Miratul M. K. Muqit
Sci Adv. 2024 Jun 7; 10(23): eadn7191. Published online 2024 Jun 7. doi: 10.1126/sciadv.adn7191
PMCID:
PMC11160474
AbstractArticlePDF–1.8M
4.
Hyperubiquitylation of DNA helicase RECQL4 by E3 ligase MITOL prevents mitochondrial entry and potentiates mitophagy
Mansoor Hussain, Aftab Mohammed, Shabnam Saifi, Swati Priya, Sagar Sengupta
J Biol Chem. 2023 Sep; 299(9): 105087. Published online 2023 Jul 24. doi: 10.1016/j.jbc.2023.105087
PMCID:
PMC10470078
AbstractArticlePDF–5.1M
5.
AR antagonists develop drug resistance through TOMM20 autophagic degradation-promoted transformation to neuroendocrine prostate cancer
Linglong Yin, Yubing Ye, Ling Zou, Jinli Lin, Yi Dai, Yongming Fu, Youhong Liu, Yuchong Peng, Yingxue Gao, Yuxin Fu, Xuli Qi, Tanggang Deng, Songwei Zhang, Xiong Li
J Exp Clin Cancer Res. 2023; 42: 204. Published online 2023 Aug 10. doi: 10.1186/s13046-023-02776-0
PMCID:
PMC10413764
AbstractArticlePDF–8.9M
6.
Iron induces B cell pyroptosis through Tom20–Bax–caspase–gasdermin E signaling to promote inflammation post-spinal cord injury
Chengjie Wu, Lining Wang, Sixian Chen, Lei Shi, Mengmin Liu, Pengcheng Tu, Jie Sun, Ruihua Zhao, Yafeng Zhang, Jianwei Wang, Yalan Pan, Yong Ma, Yang Guo
J Neuroinflammation. 2023; 20: 171. Published online 2023 Jul 22. doi: 10.1186/s12974-023-02848-0
PMCID:
PMC10362643
AbstractArticlePDF–17M
7.
LncRNA ZNNT1 induces p53 degradation by interfering with the interaction between p53 and the SART3-USP15 complex
Kenzui Taniue, Takeaki Oda, Tomoatsu Hayashi, Yuki Kamoshida, Yasuko Takeda, Anzu Sugawara, Yuki Shimoura, Lumi Negishi, Takeshi Nagashima, Mariko Okada-Hatakeyama, Yoshifumi Kawamura, Naoki Goshima, Nobuyoshi Akimitsu, Tetsu Akiyama
PNAS Nexus. 2023 Jul; 2(7): pgad220. Published online 2023 Jul 4. doi: 10.1093/pnasnexus/pgad220
PMCID:
PMC10337854
AbstractArticlePDF–851K
8.
Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell
Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low
Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120
PMCID:
PMC10151615
AbstractArticlePDF–2.9M
9.
Elucidation of ubiquitin-conjugating enzymes that interact with RBR-type ubiquitin ligases using a liquid–liquid phase separation–based method
Ryota Hayashida, Reika Kikuchi, Kenichiro Imai, Waka Kojima, Tatsuya Yamada, Miho Iijima, Hiromi Sesaki, Keiji Tanaka, Noriyuki Matsuda, Koji Yamano
J Biol Chem. 2023 Feb; 299(2): 102822. Published online 2022 Dec 21. doi: 10.1016/j.jbc.2022.102822
PMCID:
PMC9860496
AbstractArticlePDF–6.6M
10.
LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF‐κB to the nucleus
Zhixiao Wu, Lena A Berlemann, Verian Bader, Dominik A Sehr, Eva Dawin, Alberto Covallero, Jens Meschede, Lena Angersbach, Cathrin Showkat, Jonas B Michaelis, Christian Münch, Bettina Rieger, Dmitry Namgaladze, Maria Georgina Herrera, Fabienne C Fiesel, Wolfdieter Springer, Marta Mendes, Jennifer Stepien, Katalin Barkovits, Katrin Marcus, Albert Sickmann, Gunnar Dittmar, Karin B Busch, Dietmar Riedel, Marisa Brini, Jörg Tatzelt, Tito Cali, Konstanze F Winklhofer
EMBO J. 2022 Dec; 41(24): e112006. Published online 2022 Nov 18. doi: 10.15252/embj.2022112006
PMCID:
PMC9753471
AbstractArticlePDF–4.3M
11.
ATP13A2 modifies mitochondrial localization of overexpressed TOM20 to autolysosomal pathway
Yuta Hatori, Yukina Kanda, Saori Nonaka, Hiroshi Nakanishi, Takeo Kitazawa
PLoS One. 2022; 17(11): e0276823. Published online 2022 Nov 29. doi: 10.1371/journal.pone.0276823
PMCID:
PMC9707766
AbstractArticlePDF–2.0M
12.
Structural basis of Tom20 and Tom22 cytosolic domains as the human TOM complex receptors
Jiayue Su, Desheng Liu, Fan Yang, Mei-Qing Zuo, Chang Li, Meng-Qiu Dong, Shan Sun, Sen-Fang Sui
Proc Natl Acad Sci U S A. 2022 Jun 28; 119(26): e2200158119. Published online 2022 Jun 22. doi: 10.1073/pnas.2200158119
PMCID:
PMC9245660
AbstractArticlePDF–3.2M
13.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
14.
Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis
Fenglong Jiao, Clinton Yu, Andrew Wheat, Xiaorong Wang, Scott D. Rychnovsky, Lan Huang
Anal Chem. Author manuscript; available in PMC 2022 Apr 30.
Published in final edited form as: Anal Chem. 2022 Mar 15; 94(10): 4236–4242. Published online 2022 Mar 2. doi: 10.1021/acs.analchem.1c04485
PMCID:
PMC9056026
AbstractArticlePDF–1.0M
15.
C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy
Bing-Ru Yan, Taoyingnan Li, Etienne Coyaud, Estelle M. N. Laurent, Jonathan St-Germain, Yuhuan Zhou, Peter K. Kim, Brian Raught, John H. Brumell
Autophagy. 2022; 18(4): 829–840. Published online 2021 Aug 25. doi: 10.1080/15548627.2021.1960116
PMCID:
PMC9037554
AbstractArticlePDF–4.1M
16.
EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation
Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing
Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6
PMCID:
PMC8748958
AbstractArticlePDF–3.0M
17.
The receptor subunit Tom20 is dynamically associated with the TOM complex in mitochondria of human cells
Maniraj Bhagawati, Tasnim Arroum, Niklas Webeling, Ayelén González Montoro, Henning D. Mootz, Karin B. Busch
Mol Biol Cell. 2021 Oct 1; 32(20): br1. doi: 10.1091/mbc.E21-01-0042
PMCID:
PMC8684756
AbstractArticlePDF–1.7M
18.
Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context
Marcel Morgenstern, Christian D. Peikert, Philipp Lübbert, Ida Suppanz, Cinzia Klemm, Oliver Alka, Conny Steiert, Nataliia Naumenko, Alexander Schendzielorz, Laura Melchionda, Wignand W.D. Mühlhäuser, Bettina Knapp, Jakob D. Busch, Sebastian B. Stiller, Stefan Dannenmaier, Caroline Lindau, Mariya Licheva, Christopher Eickhorst, Riccardo Galbusera, Ralf M. Zerbes, Michael T. Ryan, Claudine Kraft, Vera Kozjak-Pavlovic, Friedel Drepper, Sven Dennerlein, Silke Oeljeklaus, Nikolaus Pfanner, Nils Wiedemann, Bettina Warscheid
Cell Metab. 2021 Dec 7; 33(12): 2464–2483.e18. doi: 10.1016/j.cmet.2021.11.001
PMCID:
PMC8664129
AbstractArticle
19.
Integrative Multi-omics Landscape of Non-structural Protein 3 of Severe Acute Respiratory Syndrome Coronaviruses
Ruona Shi, Zhenhuan Feng, Xiaofei Zhang
Genomics Proteomics Bioinformatics. 2021 Oct; 19(5): 707–726. Published online 2021 Nov 10. doi: 10.1016/j.gpb.2021.09.007
PMCID:
PMC8578027
AbstractArticlePDF–4.1M
20.
Protein interaction landscapes revealed by advanced in vivo cross-linking–mass spectrometry
Andrew Wheat, Clinton Yu, Xiaorong Wang, Anthony M. Burke, Ilan E. Chemmama, Robyn M. Kaake, Peter Baker, Scott D. Rychnovsky, Jing Yang, Lan Huang
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2023360118. Published online 2021 Aug 4. doi: 10.1073/pnas.2023360118
PMCID:
PMC8364181
AbstractArticlePDF–3.0M

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